This lesson outlines the need for energy in living organisms, and describes how ATP is formed by phosphorylation in respiration and photosynthesis. The engaging and detailed PowerPoint and accompanying resources have been primarily designed to cover points 12.1 (a, b, c & e) of the CIE A-level Biology specification but can be used as a revision of topics 1, 4 and 6 as the students knowledge of cell structure, membrane transport and ATP is constantly challenged. As this is the first lesson in topic 12 (respiration), it has been specifically planned to act as an introduction to this cellular reaction and provides important details about glycolysis, the Krebs cycle and oxidative phosphorylation that will support the students to make significant progress when these stages are covered during individual lessons. Photophosphorylation is also introduced so students are prepared for the light-dependent reaction of photosynthesis in topic 13. The main focus of the start of the lesson is the demonstration of the need for energy in a variety of reactions that occur in living organisms. Students met ATP in topics 1 and 6, so a spot the errors task is used to check on their recall of the structure and function of this molecule. This will act to remind them that the release of energy from the hydrolysis of ATP can be coupled to energy-driven reactions in the cell such as active transport and a series of exam-style questions are used to challenge them on their knowledge of this form of membrane transport. They will also see how energy is needed for protein synthesis and DNA replication and the maintenance of resting potential, before more questions challenge them to apply their knowledge of cell structure and transport to explain how it is needed during the events at a synapse. The rest of the lesson focuses on the production of ATP by substrate-level, oxidative and photophosphorylation and the students will learn when ATP is formed by each of these reactions and will see how the electron transport chain in the membranes in the mitochondria and chloroplast is involved

This lesson describes the processes that take place during interphase, mitosis and cytokinesis and outlines how checkpoints regulate the cell cycle. The PowerPoint and accompanying resources have been designed to cover points 2.1.6 (a & b) of the OCR A-level Biology specification and prepares the students for the upcoming lessons on the main stages of mitosis and its significance in life cycles The students were introduced to the cell cycle at GCSE so this lesson has been planned to build on that knowledge and to emphasise that the M phase which includes mitosis (nuclear division) only occupies a small part of the cycle. The students will learn that interphase is the main stage and that this is split into three phases, G1, S and G2. A range of tasks which include exam-style questions, guided discussion points and quick quiz competitions are used to introduce key terms and values and to describe the main processes that occur in a very specific order. There is also a focus on the checkpoints, such as the restriction point that occurs before the S phase to ensure that the cell is ready for DNA replication. Extra time is taken to ensure that key terminology is included and understood, such as sister chromatid and centromere, and this focus helps to show how it is possible for genetically identical daughter cells to be formed at the end of the cycle. Important details of mitosis are introduced so students are ready for the next lesson, before the differences in cytokinesis in animal and plant cells are described.

This lesson describes how to use the Spearman’s rank correlation coefficient to consider the relationship between two sets of data. The PowerPoint and accompanying exam-style question are part of the final lesson in a series of 3 which have been designed to cover point 4.2.2 (f) of the OCR A-level Biology A specification. The previous two lessons described the different types of variation and explained how to calculate the standard deviation and how to use the Student’s t-test to compare two means. As with the previous lesson, a step by step guide is used to walk the students through the use of the formula to generate the rank coefficient and to determine whether there is a positive correlation, no correlation or a negative correlation. The students are also reminded of the null hypothesis and will be shown how to accept or reject this hypothesis and to determine significance. The students will work through an example with the class and then are given the opportunity to apply their newly-acquired knowledge to an exam-style question. The mark scheme is displayed on the PowerPoint so they can assess their understanding

This lesson describes how biodiversity is generated through natural selection and leads to behavioural, anatomical and physiological adaptations. The PowerPoint and accompanying resources have been designed to cover specification points (m) & (n) in AS unit 2, topic 1 of the WJEC A-level Biology specification President Trump’s error ridden speech about antibiotics is used at the beginning of the lesson to remind students that this is a treatment for bacterial infections and not viruses as he stated. Moving forwards, 2 quick quiz competitions are used to introduce MRSA and then to get the students to recognise that they can use this abbreviation to remind them to use mutation, reproduce, selection (and survive) and allele in their descriptions of evolution through natural selection. The main task of the lesson challenges the students to form a description that explains how this strain of bacteria developed resistance to methicillin to enable them to see the principles of natural selection. This can then be used when describing how the anatomy of the modern-day giraffe has evolved over time. The concept of convergent evolution is introduced and links are made to the need for modern classification techniques as covered earlier in topic 1. Moving forwards, students will understand how natural selection leads to adaptations and a quick quiz competition introduces the different types of adaptation and a series of tasks are used to ensure that the students can distinguish between anatomical, behavioural and physiological adaptations. The Marram grass is used to test their understanding further, before a step by step guide describes how the lignified cells prevent a loss of turgidity. Moving forwards, the students are challenged to explain how the other adaptations of this grass help it to survive in its environment. A series of exam-style questions on the Mangrove family will challenge them to make links to other topics such as osmosis and the mark schemes are displayed to allow them to assess their understanding. The final part of the lesson focuses on the adaptations of the anteater but this time links back to the topic of taxonomy and students have to answer questions about species and classification hierarchy. Due to the extensiveness of this lesson and the detail contained within the resources, it is estimated that it will take in excess of 2 hours of allocated A-level teaching time to deliver this lesson.

This lesson describes the gross structure of the human gas exchange system, including the trachea, bronchi, bronchioles and lungs. The PowerPoint and accompanying resources are part of the third lesson in a series of 6 which have been designed to cover the detail of topic 3.2 in the AQA A-level Biology specification which is titled gas exchange and this lesson has been specifically planned to prepare students for the next lesson where the essential features of the alveoli are described. The lesson is filled with a range of activities such as guided discussion periods, exam-style questions (with markschemes) and quiz competitions and these run alongside the slides containing the detailed A-level Biology content to cover the following features: The incomplete rings of cartilage, ciliated pseudostratified columnar epithelium and goblet cells in the trachea The narrowing airways of the primary, secondary and tertiary bronchi The elastic fibres and smooth muscle in the terminal and respiratory bronchioles The pleural cavity and fluid of the lungs When describing the production of mucus by the goblet cells in the trachea, time is taken to consider cystic fibrosis and the inheritance of this autosomal recessive disorder. Students will be supported in working out genotypes from a pedigree tree to prepare them for the topic of inheritance (7.1)

This lesson explains the meaning of biodiversity and describes how it can be assessed in a habitat, in a species level at a genetic level and at a molecular level. The engaging PowerPoint and accompanying resources have been designed to cover points (h-l) in AS unit 2, topic 1 of the WJEC A-level Biology specification but as a lot of genetic content is covered when considering diversity within a species, this lesson can be used as an introduction to the upcoming topics of inheritance A quiz competition called BIOLOGICAL TERMINOLOGY SNAP runs over the course of the lesson and this will engage the students whilst challenging them to recognise key terms from their definitions. This quiz introduces biodiversity, loci, allele and recessive and each of these terms is put into context once introduced. Once biodiversity has been revealed, the students will learn that they are expected to be able to assess the biodiversity within a habitat and within a species and at a molecular level. The variety of alleles in the gene pool of a population increases the genetic diversity so a number of examples are used to demonstrate how the number of phenotypes increases with the number of alleles at a locus. The CFTR gene is used to demonstrate how 2 alleles results in 2 different phenotypes and therefore genetic diversity. Moving forwards, students will discover that more than 2 alleles can be found at a locus and they are challenged to work out genotypes and phenotypes for a loci with 3 alleles (shell colour in snails) and 4 alleles (coat colour in rabbits). Moving forwards, a step by step guide to complete a worked example to calculate a value of D using Simpson’s index of diversity. Students are challenged with a range of exam-style questions where they have to apply their knowledge and all mark schemes are displayed and clearly explained within the PowerPoint to allow students to assess their understanding and address any misconceptions if they arise. The final part of the lesson considers how DNA fingerprinting can be used to assess biodiversity at a molecular level and again a series of exam-style questions are used to challenge the students to apply their newly-acquired knowledge to an unfamiliar situation.

This lesson introduces the three-domain system and describes some of the biochemical methods used in classification to overcome the problems of morphological convergence. The PowerPoint and accompanying resources have been designed to cover points [c] and [e] in AS unit 2, topic 1 of the WJEC A-level Biology specification The lesson begins with an introduction of Carl Woese and goes on to describe how he is most famous for his definition of the Archaea as a new domain of life. Students were introduced to domains and the other classification taxa in a previous lesson, so their recall of this knowledge is continually tested and built upon as details are added. Students will discover the key differences between Archaea and Bacteria that led to the splitting of the prokaryotae kingdom and the addition of this higher classification rank. Moving forwards, the rest of the lesson considers other molecules that can be compared between species for classification purposes and the primary structure of cytochrome is described and discussed. At this point in the lesson, the students are also tested on their knowledge of the nature of the genetic code and have to explain how mutations to DNA can also be used for comparative purposes. The use of DNA genetic fingerprinting is briefly introduced and this is described in greater detail in a future lesson about assessing biodiversity at a molecular level

This lesson describes the adaptations of gas exchange surfaces in single-celled organisms, insects, bony fish and dicotyledonous plants. The PowerPoint and accompanying worksheets are part of the first lesson in a series of 6 lessons that have been designed to cover the detail of point 3.2 (Gas exchange) of the AQA A-level Biology specification. The lesson has been intricately planned to challenge the students on their understanding of the surface area to volume ratio (as covered in the previous lesson) and to make direct links to upcoming lessons on gas exchange and transport systems in humans. The lesson begins by explaining that single-celled organisms are able to diffuse oxygen and carbon dioxide across their body surface but that as organisms increase in size and their SA/V ratio decreases, they need adaptations at their gas exchange surfaces to be able to obtain the oxygen to meet their metabolic demands. This leads into the next part of the lesson which describes the roles of the following structures in insects and bony fish: spiracles, tracheae, tracheoles and tracheole fluid operculum, gill arch, gill filaments and lamellae The next task challenges the students to use their knowledge of topics 1 and 2 to come up with the letters that form the key term, countercurrent flow. This is a key element of the lesson and tends to be a principle that is poorly understood, so extra time is taken to explain the importance of this mechanism. Students are shown two diagrams, where one contains a countercurrent system and the other has the two fluids flowing in the same direction, and this is designed to support them in recognising that this type of system ensures that the concentration of oxygen is always higher in the oxygenated water than in the blood in the lamellae. The final part of the lesson describes the role of the stomata and the mesophyll cells in the gas exchange of a dicotyledonous plant. Students will learn that guard cells contain chloroplasts which generate ATP and then they are challenged to order a series of statements to form a description of the events that result in the opening of the stomata. The differing structures of the spongy mesophyll and palisade mesophyll cells are then considered before the students are challenged to explain how carbon dioxide moves through the leaf after entering via the stomata and then how water vapour and oxygen leave. Clear links are made to the loss of water vapour by transpiration so students are prepared for the lessons covering this biological process later in topic 3.

This lesson describes the in situ and ex situ methods of maintaining biodiversity, and discusses the advantages and disadvantages associated with both. The engaging PowerPoint and accompanying worksheets have been primarily designed to cover point 4.2.1 (h) of the OCR A-level Biology A specification but the lesson has been carefully planned to enable links to be made to some related topics which are found later in the course such as classification, evolution through natural selection and the Founder effect. Hours of research has gone into the planning of this lesson to source interesting examples that increase the relevance of the biological content concerning in situ conservation, and these include the Lizard National Nature Reserve in Cornwall, the Lake Télé Community reserve in the Republic of Congo and the marine conservation zone in the waters surrounding Tristan da Cunha. Students will learn how this form of active management conserves habitats and species in their natural environment, with the aim of minimising human impact whilst maintaining biodiversity. The main issues surrounding this method are discussed, including the fact that the impact of this conservation may not be significant if the population has lost much of its genetic diversity and that despite the management, the conditions that caused the species to become endangered may still be present. A number of quick quiz competitions are interspersed throughout the lesson to introduce key terms and values in a fun and memorable way and one of these challenges them to use their knowledge of famous scientists to reveal the surname, Fossey. Dian Fossey was an American conservationist and her years of study of the mountain gorillas is briefly discussed along with the issue that wildlife reserves can draw poachers and tourists to the area, potentially disturbing the natural habitat. To enrich their understanding of ex situ conservation, the better known examples of ZSL London zoo, Kew Gardens and the Millennium Seed Bank Project in Wakehurst are used. Students will understand how conserving animal species outside of their natural habitat enables human intervention that ensures the animals are fed and given medical assistance when needed as well as reproductive assistance to increase the likelihood of the successful breeding of endangered species. As with the in situ method, the disadvantages are also discussed and there is a focus on the susceptibility of captive populations to diseases as a result of their limited genetic diversity. The final part of the lesson considers how seed banks can be used to ensure that plant species avoid extinction and how the plants can be bred asexually to increase plant populations quickly. Due to the extensiveness of this lesson, it is estimated that it will take in excess of 2/3 hours of allocated A-level teaching time to cover the tasks and content that is included in the lesson.

This lesson describes the principles of ex situ conservation and discusses the advantages and issues surrounding this method. The PowerPoint and accompanying worksheet are part of the second lesson in a series of 2 which have been designed to cover the content of point 3.3 (iii) of the Edexcel A-level Biology B specification and it closely ties in with the previous lesson on in situ conservation. To enrich their understanding of ex situ conservation, the well-known examples of ZSL London zoo, Kew Gardens and the Millennium Seed Bank Project in Wakehurst are used. Students will understand how conserving animal species outside of their natural habitat enables human intervention that ensures the animals are fed and given medical assistance when needed as well as reproductive assistance to increase the likelihood of the successful breeding of endangered species. As with the in situ method in the previous lesson, the issues are also discussed and there is a focus on the susceptibility of captive populations to diseases as a result of their limited genetic diversity. The final part of the lesson considers how seed banks can be used to ensure that plant species avoid extinction and how the plants can be bred asexually to increase plant populations quickly.

This lesson describes the effect that treaties such as CITES have had on global diversity. The PowerPoint and accompanying worksheets have been primarily designed to cover point 10.4 (ii) of the Edexcel A-level Biology B specification but has been planned to constantly challenge them on their knowledge of topic 3.3 (biodiversity) as a local conservation agreement is also considered Many hours of research have gone into the planning of this lesson to ensure that a range of interesting biological examples are included, with the aim of fully engaging the students in the material to increase its relevance. The students will learn that the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) was first agreed in 1973 and that 35000 species are currently found in appendix I, II or III. Time is taken to go through the meaning of each appendix and then the following animal and plant species are used to explain the finer details of the agreement: Tree pangolin, eastern black rhino for CITES appendix I Darwin’s orchid for CITES appendix II Four-horned antelope for CITES appendix III Exam-style questions are used to check on their understanding of the current topic as well as to challenge their knowledge of previously-covered topics such as the functions of keratin, when considering the structure of the rhino horn. Each of these questions has its own markscheme which is embedded in the PowerPoint and this allows the students to constantly assess their progress. The final part of the lesson considers the Countryside Stewardship Scheme as a local conservation agreements and discusses the reasons behind some of the key points. Students are told that farmers, woodland owners, foresters and land managers can apply for funding for a range of options including hedgerow management, low input grassland, buffer strips, management plans and soil protection options. The importance of the hedgerows for multiple species is discussed, and again a real-life example is used with bats to increase the likelihood of retention. The last task challenges them to use their overall knowledge of biodiversity to explain why buffer strips consisting of multiple types of vegetation are used and to explain why these could help when a farmer is using continuous monoculture.

This lesson describes the action of bactericidal and bacteriostatic antibiotics, as illustrated by penicillin and tetracycline. The engaging PowerPoint and accompanying resources have been designed to cover point 6.3 (i) of the Edexcel A-level Biology B specification but it has been specifically planned to make continual links to earlier lessons in topic 6 and to protein synthesis as covered in topic 1 The lesson begins by challenging the students to use their general biological knowledge and any available sources to identify the suffixes cidal and static. Students will learn that when the prefix is added, these form the full names of two types of antibiotics. Their understanding of terminology is tested further as they have to recognise that Polymyxin B is an example of a bactericidal antibiotic as its actions would result in the death of the bacterial cell. Time is then taken to describe the action of penicillin and students will learn how inhibitors and modified versions of this antibiotic are used to overcome those bacteria who have resistance. Tetracycline is used as the example of a bacteriostatic antibiotic and students will discover that its prevention of the binding of tRNA that inhibits protein synthesis and this reduction and stopping of growth and reproduction is synonymous with these drugs. Students are challenged on their knowledge of translation and will also be given time for a class discussion to understand that these antibiotics encourage the body’s immune system to overcome the pathogen in natural, active immunity. The final part of the lesson uses a quick quiz competition and a series of exam-style questions to ensure that students can recognise these different types of antibiotics from descriptions.

This lesson outlines how penicillin acts on bacteria and why antibiotics do not affect viruses. The PowerPoint and accompanying resources have been designed to cover point 10.2 (a) of the CIE A-level Biology specification and also introduces the concept of bactericidal and bacteriostatic antibiotics, as illustrated by penicillin and tetracycline. The lesson begins with an engaging task, where the students have to identify the surnames of famous scientists from their descriptions to reveal the surname Fleming. This introduces Sir Alexander Fleming as the microbiologist who discovered penicillin in 1928. Time is taken to describe penicillin as a group of antibiotics that contain a beta-lactam ring in their molecular structure. Using this information and their knowledge of bacterial cell structure from topic 1, the students have to complete a passage describing how penicillin inhibits the formation of cross links in cell wall synthesis. A series of exam-style questions are then used to make links to the upcoming topic of antibiotic resistance. The next part of the lesson focuses on the differences between bactericidal and bacteriostatic antibiotics and the students will learn that penicillin is bactericidal as the weakening of the cell wall leads to lysis and death. Tetracycline is used as the example of a bacteriostatic antibiotic and students will discover that it is the prevention of the binding of tRNA that inhibits protein synthesis and that this reduction and prevention of growth and reproduction is synonymous with these antimicrobial agents. Students are challenged on their knowledge of translation and will also be given time for a class discussion to understand that these antibiotics work in tandem the body’s immune system to overcome the pathogen The final part of the lesson explains why antibiotics are ineffective against viruses.

This lesson describes the main stages of mitosis and explains the significance of this type of nuclear division for the daughter cells produced by the cycle. The PowerPoint and accompanying resources have been designed to cover points 6 (a & b) in topic 6 of AS unit 1 of the WJEC A-level Biology specification and the process of cytokinesis is also described. Depending upon the exam board taken at GCSE, the knowledge and understanding of mitosis will differ considerably between students and there may be a number of misconceptions. This was considered at all points during the planning of the lesson so that existing errors are addressed and key points are emphasised throughout. Their understanding of interphase is challenged at the start of the lesson to ensure that they realise that it is identical pairs of sister chromatids that enter the M phase. The main part of the lesson focuses on prophase, metaphase, anaphase and telophase and describes how the chromosomes behave in these stages. There is a focus on the centrioles and the spindle fibres that they produce which contract to drag one chromatid from each pair in opposite directions to the poles of the cell. The remainder of the lesson is a series of understanding and application questions where students have to identify the various roles of mitosis in living organisms as well as tackling a Maths in a Biology context question. The lesson concludes with a final quiz round of MITOSIS SNAP where they only shout out this word when a match is seen between the name of a phase, an event and a picture.

This lesson describes the effects of pH on enzyme activity. The PowerPoint and accompanying resources are part of the first lesson in a series of 3 lessons which have been designed to cover the content of point 2.1.4 (d)(i)of the OCR A-level Biology A specification. The lesson begins with a short discussion, where the students are challenged to identify how the stomach and the small intestine differ in terms of a particular condition and to explain why the conditions in these neighbouring digestive organs are so important. This introduces pepsin and trypsin and these protease enzymes play a key role throughout the lesson as they are good examples of how different extracellular enzymes have different optimum pH values (which are not necessarily 7.0). Moving forwards, students will discuss how the rate of an enzyme-controlled reaction will change if there are small or large changes in pH, and then time is taken to ensure that students can explain these changes with reference to tertiary structure bonds and the shape of the active site. Through the use of a quick quiz competition, the students will be reminded of the key term “buffer” and a series of questions are used to challenge their understanding of how these substances could be used in a practical investigation. They will also learn how buffers are found in blood plasma as well as in red blood cells in the form of haemoglobin. With there being such a considerable proportion of marks for Maths in a Biology context questions in the A-level assessments, the remainder of the lesson challenges the students to use a given formula to calculate the pH of blood when given the hydrogen ion concentration and to calculate percentage decrease. These questions have been differentiated to give assistance to those that need the support Please note that this is a lesson which describes the effect on enzyme activity, as described in 2.1.4 (d)(i), and not the details of the practical investigation which is covered in a later lesson

This lesson revisits the topic of random and systematic errors and also challenges students on other scientific skills such as identifying variables. Students tend to find this topic confusing, so the PowerPoint and accompanying resources have been designed to support them to identify whether an error is random or systematic and then to understand what to do next. The lesson guides the students through a series of real life examples and shows them how to spot each type of error. There is a considerable mathematical element to this lesson, including the calculation of means or missing values in a table. The lesson concludes with a series of exam-style questions where the students have to apply their understanding of identifying errors, variables and calculating means.