This lesson describes how the structure of the heart and the circulatory system is related to its function. The PowerPoint lesson and accompanying resources have been designed to cover the detail of point 8.8 of the Edexcel GCSE Biology and Combined Science specifications and includes descriptions of the role of the major blood vessels, the heart valves, and the relative thickness of the chamber walls. The lesson starts with an extract from Friends and challenges the students to recognise that full sized aortic pumps is a thesaurus version of big hearts. This reiterates the basic function of the heart that was met at KS2 and KS3 and moving forwards, the students will learn that it is the contraction of the cardiac muscle in the walls of the four heart chambers that allows this to happen. Students are provided with a diagram throughout the lesson which will be annotated as new structures are encountered and they begin by labelling the two atria and ventricles. The focus of the lesson is the relationship between structure and function so time is taken to consider the different roles of the atria and ventricles, as well as the right ventricle versus the left ventricle. Students will be able to observe from their diagram that the left ventricle has the thickest wall and they will be challenged to explain why later in the lesson once more detailed knowledge has been added. The next part of the lesson introduces the pulmonary artery and vein and a task challenges the students to consider the relationship between the heart and the lungs, and their prior knowledge of the adaptations of the alveoli is also tested. The remainder of the lesson discusses the double circulatory system and the heart valves. Understanding checks are found throughout the lesson and mark schemes are embedded into the PowerPoint to allow the students to assess their progress.

This fully-resourced lesson describes the meaning of directional and stabilising selection and uses real-life examples to develop student understanding. The PowerPoint and accompanying resources are part of the 3rd lesson in a series of 4 that have been designed to cover the details of topic 4.4 (genetic diversity and adaptation) of the AQA A-level biology specification. As stated in the specification, antibiotic resistance is used as the key example to explain directional selection whereas human baby birth weight explains stabilising selection. The lesson is filled with current understanding checks so any misunderstandings can be immediately addressed, and also prior knowledge checks, where students are expected to recall key details from lessons in this topic so they can make important links. The lesson concludes with a short quiz called “SELECT that word” (shown on the cover image) where students have to identify the types of selection from clues to reveal a key biological word.

This lesson describes succession as the gradual, progressive changes that occur in a community over time. The PowerPoint and accompanying resources are part of lesson 3 in a series of 4 lessons which have been planned to cover the content included in topic 7.4 of the AQA A-level biology specification. In line with the specification, the lesson describes primary succession and explains how the community changes from the initial colonisation by the pioneer species to the establishment of a climax community. Time is taken to focus on the lichen as a pioneer species and to explain how their actions lead to the production of soil and the subsequent colonisation by more hardy species. The island of Surtsey is used as a real-world example to deepen student understanding. Understanding checks and prior knowledge checks are embedded throughout the lesson (along with the answers) so students can assess their progress on the current topic and also test their ability to link to previously covered topics. Due to the high mathematical content of the AQA assessments, a maths in a biology context question has also been included.

This revision lesson challenges students to explain the results of an osmosis investigation and to calculate accelerations using 2 equations. The PowerPoint and accompanying resources have been designed to check on the understanding of these two topics as detailed in the AQA GCSE biology, physics and combined specifications. The lesson contains a range of tasks including worked examples, exam questions and quizzes which will remind students that water molecules move across partially permeable membranes by osmosis and how changes in the mass of a potato can be used to compare water concentrations in the potato and solution. Students will also recall that acceleration can be calculated from velocity-time graphs using change in velocity/time as well as through the use of F=ma.

This fully-resourced revision lesson allows students to check on their understanding of Linnaeus’s and Woese’s classification systems. The engaging PowerPoint and accompanying resources have been designed to challenge the details of point B6.4 of the AQA GCSE biology and combined science specifications. The lesson contains a range of tasks including exam-questions and quizzes which provide opportunities for the students to assess their knowledge of kingdom, phylum, class, order, family, genus and species as the classification taxa and to recognise the binomial naming system. The lesson also reminds students that the three domain-system divides the Prokaryote kingdom into Archaea and Bacteria and describes how this system was developed once new evidence was discovered. As well as testing the content of B6.4, this lesson uses a series of questions to challenge understanding of linked topics which include eukaryotic and prokaryotic cell structures, microscopes, communicable diseases and ecological terms. This lesson has been planned for revision purposes in the lead up to the GCSE exams or before end of topic tests or mocks.

This lesson describes the biological meaning of species, populations, gene pool and allele frequency and explains how these terms are linked. The PowerPoint and accompanying resources are part of the 1st lesson in a series of 2 lessons that cover the detail of specification point 7.2 (Populations) of the AQA A-level biology. The two living species of the African elephant, the forest and bush elephant, are used as examples to demonstrate the meaning of species and to show how they exist as one or more populations. A quick quiz introduces the term gene pool in an engaging way and then the allele frequency of three versions of the GBA gene demonstrates how these frequencies can change in small populations. In doing so, students are briefly introduced to genetic drift which they will encounter in an upcoming topic. The students are challenged throughout the lesson with understanding checks and prior knowledge checks as well as exam-based questions where they have to comment on the validity of a scientist’s conclusion. The other lesson in topic 7.2 is the Hardy-Weinberg principle.

This lesson describes the pathway by which the translation of mRNA into proteins can be prevented by siRNA and miRNA molecules. The engaging and detailed PowerPoint and accompanying resources are part of the final lesson in a series of 4 lessons that cover the detail of point 8.2.2 of the AQA A-level biology specification. The lesson begins with an exisiting knowledge check, as the students are challenged to recognise the processes of DNA methylation and histone acetylation, before RNA interference is introduced as another way by which gene expression is controlled in eukaryotes. Moving forwards, a quick quiz round introduces small interfering RNA (siRNA) and students will learn how this double-stranded, non-coding RNA is normally just 21 base pairs long. A step by step guide then describes the action of siRNA in preventing translation, through the cutting of the target mRNA into fragments which are then degraded. Time is taken to consider the possible application of siRNA molecules in the treatment of HIV and then cystic fibrosis, and the latter involves a series of exam-style questions which challenge the students on their understanding of this topic as well as the recall of content from the other 7 AQA topics. The remainder of the lesson focuses on microRNA (miRNA) and students will understand how this molecule is produced and how its action differs to that of siRNA in mammalian cells.

This lesson describes how epigenetic changes like DNA methylation and histone modification can modify the activation of certain genes. The PowerPoint and accompanying resources have been planned to cover points 3.14 ii & iii of the Pearson Edexcel A-level biology (Salters-Nuffield) specification. The lesson begins by introducing the prefix epi- as meaning on or above in Greek to allow students to recognise that epigenetics refers to changes in gene function due to factors beyond the genetic code. Moving forwards, they will learn that DNA methylation involves the attachment of a methyl group to cytosine and will come to understand how this inhibits transcription. They are challenged to recognise the pathogenesis of atherosclerosis through a variety of tasks before reading through a source detailing the results of a study between this cardiovascular condition and DNA methylation. The remainder of the lesson considers how the acetylation of histone proteins affects the expression of genes. Understanding and prior knowledge checks are embedded throughout the lesson (along with the answers) to allow the students to assess their progress on this topic and to encourage them to make links to the content of topics 1 - 2.

This lesson describes how iPS cells are formed from fibroblasts and discusses why this method is less controversial than the use of embryonic stem cells. The PowerPoint and accompanying resources are part of the 2nd lesson in a series of 2 lessons which covers the content of point 7.3 (stem cells) of the Edexcel A-level biology B specification. The lesson begins with a SPOT THE ERRORS task, where students have to use their knowledge of pluripotent cells from the previous lesson to identify the 3 errors and make corrections. The aim of this task is to remind them that pluripotent cells are found in embryos and can divide in unlimited numbers before finally becoming fully differentiated somatic cells. Moving forwards, the students are introduced to fibroblasts as examples of these somatic cells and the opportunity is taken to challenge their knowledge of collagen as this is a substance produced by these cells. The answers are embedded into the PowerPoint to allow the students to assess their recall of this topic 1 content. A quick quiz is used to introduce the acronym iPS and students will learn that fibroblasts can be reprogrammed to form induced pluripotent cells using specific transcription factors. The remainder of the lesson challenges them to answer questions about the use of iPS cells in regenerative medicine after reading a passage about an example. This allows them to recognise that deriving these cells from adult tissues as opposed to embryonic stem cells raises less problems and the transplant into the same person reduces the risk of rejection.

At the end of topic 3, or in the lead up to mocks or final A-level exams, students can use this lesson to assess their understanding of topic 3 content. The lesson consists of 20 multiple-choice questions, which have been written to challenge the students on the detail of their knowledge, as well as a PowerPoint which contains the answers, explanations and key points related to the specification. The PowerPoint also contains other topic 3 knowledge checks on content which isn’t directly questioned in the multiple-choice assessment, and prior knowledge checks to encourage the students to recognise the links to topic 1 and 2. The following topics are challenged by the multiple-choice questions: Surface area to volume ratio Gas exchange (in animals and plants) Digestion and absorption Mass transport in animals Mass transport in plants

This revision lesson contains an assessment of 20 multiple-choice questions and a PowerPoint with the answers and related key points from the specification. The 20 questions have been written to cover the content of topic 4 of the AQA A-level biology specification, providing the students with an opportunity to assess their understanding and highlight those areas which need further attention. All 7 sub-topics of topic 4 are covered by at least one question and there are several questions which challenge mathematical skills, which aligns with the high mathematical content of the final assessments.

This lesson describes how only part of a cell’s DNA is translated and explains how the potency of a stem cell determines its ability to specialise. The engaging and detailed PowerPoint and accompanying resources have been planned to cover all of the content in point 8.2.1 of the AQA A-level biology specification. The lesson begins by challenging the students to recall any existing knowledge of stem cells, to check that they remember that these cells differentiate, before the concept of cell potency is introduced to allow them to recognise that not all cells can differentiate into the same amount of cell types. A quick quiz is used to introduce pluripotency, unipotency, totipotency and multipotency before they are challenged to use their understanding of language to order these along the potency continuum. Beginning with totipotency, time is taken to go through details of each of these cell types, including where these cells are located. During the section of the lesson considering pluripotency, induced pluripotent stem cells are discussed and their potential for use in regenerative medicine is explored. Understanding checks through exam-based questions are embedded throughout the lesson (as well as the answers) to allow students to assess their current understanding and to address any gaps immediately. There are also prior knowledge checks so students can link to other topics from the specification and there is a maths in biology question so their mathematical skills are challenged in line with that element of the course.

This fully-resourced lesson describes the stages of succession from colonisation to climax community. The PowerPoint and accompanying worksheets have been designed to cover the content of point 5.4 of the Edexcel A-level Biology A specification. As you can see from the cover image, this lesson uses a step-by-step method to guide the students through each stage of the process of succession, explaining each of the gradual, progressive changes that occur in a community over time. At each stage, time is taken to consider the organisms involved. There is a focus on lichens as examples of pioneer species and students will understand how colonisation by these organisms is critical to provide organic matter and to turn the bare ground into soil so it is habitable by other species. The island of Surtsey in Iceland is used as real-world example and shows how different parts of an area can be at different stages of succession. Understanding and prior knowledge checks are embedded into the PowerPoint (along with the answers) to allow students to assess their progress against the current topic and to encourage them to make links to previously-covered work.

This lesson describes how recombinant DNA can be produced, including the role of restriction endonucleases and DNA ligase. The PowerPoint and accompanying resources have been designed to cover the content of point 7.4 (i) of the Edexcel A-level Biology B specification. This lesson begins with the introduction of recombinant DNA technology as a process where fragments of DNA are transferred from one species to another. Over the course of the lesson, the students are guided through 5 steps in the production of the recombinant DNA, with a focus on the enzymes involved, which are reverse transcriptase, DNA polymerase, restriction endonuclease, and DNA ligase. Understanding checks and prior knowledge checks are used throughout the lesson and the answers are embedded into the PowerPoint to allow the students to assess their progress.

This detailed lesson describes the processes of PCR and electrophoresis to allow students to understand how gene sequencing can be used. The engaging PowerPoint and accompanying resource have been planned to cover the content of point 7.1 of the Edexcel A-level biology B specification. The lesson begins by comparing the number of genes in the genome with the number of base pairs, to allow students to learn that the bases in the genes only accounts for about 1.5% of the genome. This challenges them to recall that most is non-coding DNA, and the importance and usefulness of these sections are explored during the lesson. Moving forward, a step-by-step guide describes the key steps in the polymerase chain reaction, and time is taken at each step to qualify the fine details such as the use of Taq polymerase instead of human DNA polymerase. The remainder of the lesson focuses on the various uses of these DNA samples once they’ve been amplified by the PCR. The steps of the electrophoresis process are described and students will see how DNA profiling can be used in forensic science to identify criminals and for paternity tests. Understanding and prior knowledge checks are found throughout the lesson, along with the answers, to allow students to assess their grasp of the current topic as well as their ability to identify the links with previously covered topics.