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A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.

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A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
Chi-squared test (OCR A-level Biology)
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Chi-squared test (OCR A-level Biology)

(1)
This lesson guides students through the use of the chi-squared test to determine the significance of the difference between observed and expected results. It is fully-resourced with a detailed PowerPoint and differentiated worksheets that have been designed to cover point 6.1.2 © of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the test to compare the observed and expected results of a genetic cross The lesson has been written to include a step-by-step guide that demonstrates how to carry out the test in small sections. At each step, time is taken to explain any parts which could cause confusion and helpful hints are provided to increase the likelihood of success in exam questions on this topic. Students will understand how to use the phenotypic ratio to calculate the expected numbers and then how to find the critical value in order to compare it against the chi-squared value. A worked example is used to show the working which will be required to access the marks and then the main task challenges the students to apply their knowledge to a series of questions of increasing difficulty.
Allopatric and sympatric speciation (AQA A-level Biology)
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Allopatric and sympatric speciation (AQA A-level Biology)

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This fully-resourced lesson explores how new species arise when changes in the gene pool of two populations prevents members from interbreeding and producing fertile offspring. The engaging PowerPoint and accompanying resources have been designed to cover the fifth part of point 7.3 of the AQA A-level Biology specification which states that students should be able to describe allopatric and sympatric speciation. The lesson begins by using the example of a hinny, which is the hybrid offspring of a horse and a donkey, to challenge students to recall the biological classification of a species. Moving forwards, students are introduced to the idea of speciation and the key components of this process, such as isolation and selection pressures, are covered and discussed in detail. Understanding and prior knowledge checks are included throughout the lesson to allow the students to not only assess their progress against the current topic but also to make links to earlier topics in the specification. Time is taken to look at the details of allopatric speciation and how the different mutations that arise in the isolated populations and genetic drift will lead to genetic changes. The example of allopatric speciation in wrasse fish because of the isthmus of Panama is used to allow the students to visualise this process. The final part of the lesson considers sympatric speciation and again a wide variety of tasks are used to enable a deep understanding to be developed.
Topic 6.7: Response to infection (Edexcel A-level Biology B)
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Topic 6.7: Response to infection (Edexcel A-level Biology B)

4 Resources
All 4 of the lessons included in this bundle are highly-detailed to enable students to understand the sequence of events that occur during the body’s response to infection. Hours of planning have gone into the lesson PowerPoints and accompanying resources to ensure that the wide variety of tasks motivate and engage the students whilst challenging them to answer exam-style questions that cover the following specification points in topic 6.7 of the Edexcel A-level Biology B specification: The mode of action of macrophages, neutrophils and lymphocytes The development of the humoral immune response The development of the cell-mediated response The role of T and B memory cells in the secondary immune response Immunity can be natural, artificial, active or passive Vaccination can be used in the control of disease and the development of herd immunity This can be a difficult topic for students to grasp, so time is taken to go over the key details to ensure that these are emphasised and retained
Topic 5.3: Energy and ecosystems (AQA A-level biology)
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Topic 5.3: Energy and ecosystems (AQA A-level biology)

3 Resources
All 3 lessons included in this bundle are detailed and engaging and have been planned at length to cover the content of topic 5.3 of the AQA A-level biology specification, which is titled energy and ecosystems. The lessons contain a variety of tasks which introduce the biological content and then provide the students with opportunities to assess their understanding. There are also prior knowledge checks to make links to content from earlier in topic 5 and in topics 1 - 4. All the answers to the checks are embedded in the PowerPoint. If you would like to check the quality of these lessons, download the lesson titled “GPP, NPP & N” as this has been shared for free.
Aerobic respiration (Edexcel A-level Biology B)
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Aerobic respiration (Edexcel A-level Biology B)

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This detailed lesson describes each of the 4 stages of aerobic respiration and explains how this cellular reaction yields ATP and generates heat. The engaging PowerPoint and accompanying resource have been designed to cover points 5.1 (i) and (ii) of the Edexcel A-level Biology B specificaiton and acts as a clear introduction for the upcoming lessons where the finer details of glycolysis, the Link reaction and Krebs cycle and oxidative phosphorylation are described The lesson begins with an introduction to glycolysis and students will learn how this first stage of aerobic respiration is also the first stage when oxygen is not present. This stage involves 10 reactions and an opportunity is taken to explain how each of these reactions is catalysed by a different, specific intracellular enzyme. A version of “GUESS WHO” challenges students to use a series of structural clues to whittle the 6 organelles down to just the mitochondrion so that they can learn how the other three stages take place inside this organelle. Moving forwards, the key components of the organelle are identified on a diagram. Students are introduced to the stages of respiration so that they can make a link to the parts of the cell and the mitochondria where each stage occurs. Students will learn that the presence of decarboxylase and dehydrogenase enzymes in the matrix along with coenzymes and oxaloacetate allows the link reaction and the Krebs cycle to run and that these stages produce the waste product of carbon dioxide. Finally, time is taken to introduce the electron transport chain and the enzyme, ATP synthase, so that students can begin to understand how the flow of protons across the inner membrane results in the production of ATP and the the formation of water when oxygen acts as the final electron acceptor.
Topic 1: Cell structure (CIE A-level Biology)
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Topic 1: Cell structure (CIE A-level Biology)

7 Resources
As Biology is the study of living organisms which are built out of cells, a clear understanding of the topic of cell structure is critical for a student’s success in A-level Biology. Intricate planning has gone into all 7 of the lessons included in this bundle and the variety of tasks will engage and motivate the students whilst the details of the following specification points in topic 1 of the CIE A-level Biology course are covered: Topic 1.1: The microscope in cell studies Use an eyepiece graticule and stage micrometer to measure cells Use of the millimetre, micrometre and nanometre Distinguish between resolution and magnification The use of light and electron microscopes Calculate the actual sizes of specimens Topic 1.2: Cells as the basic units of living organisms Recognise eukaryotic cell structures and outline their functions State that ATP is produced in the mitochondria and the chloroplast and the role of this molecule in cells The structure of a typical prokaryotic cell The differences between eukaryotic and prokaryotic cells The key features of viruses If you would like to sample the quality of these lessons, download the magnification and resolution lesson, the eukaryotic cell structures lesson and the viruses lesson as these have been shared for free
Prokaryotic cell structure (Edexcel A-level Biology B)
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Prokaryotic cell structure (Edexcel A-level Biology B)

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This fully-resourced lesson describes the ultrastructure of a prokaryotic cell including the nucleoid, plasmid, 70S ribosomes and cell wall. The engaging PowerPoint and accompanying resources have been designed to cover specification point 2.1 (iii) of the Edexcel A-level Biology B specification but has been specifically designed to be taught after the lesson on the ultrastructure of eukaryotic cells, specification point 2.1 (v), so that comparisons can be drawn. A clear understanding of terminology is important for A-level Biology so this lesson begins with a challenge, where the students have to come up with a 3-letter prefix that they believe will translate as before or in front of . This leads into the discovery of the meaning of prokaryote as before nucleus which acts to remind students that these types of cell lack this cell structure. Links to the previous lessons on the eukaryotic cells are made throughout the lesson and at this particular point, the students are asked to work out why the DNA would be described as naked and to state where it will be found in the cell. Moving forwards, the students will discover that these cells also lack membrane bound organelles and a quick quiz competition challenges them to identify the specific structure that is absent from just a single word. In addition to the naked DNA, students will learn that there are also ribosomes in the cytoplasm and will discover that these are smaller than those found in the cytoplasm of an eukaryotic cell (but the same size as those in chloroplasts and mitochondria). The remainder of the lesson focuses on the composition of the cell wall, the additional features of prokaryotic cells such as plasmids and there is also the introduction of binary fission as the mechanism by which these organisms reproduce so that students can recognise that prokaryotic cells do not contain centrioles
Competitive & non-competitive inhibitors (AQA A-level Biology)
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Competitive & non-competitive inhibitors (AQA A-level Biology)

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This lesson describes and explains how increasing the concentration of inhibitors affects the rate of an enzyme-controlled reaction. The PowerPoint and accompanying resource are the last in a series of 5 lessons which cover the content detailed in point 1.4.2 of the AQA A-level Biology specification and describes the effect of both competitive and non-competitive inhibitors. The lesson begins with a made up round of the quiz show POINTLESS called “Biology opposites” and this will get the students to recognise that inhibition is the opposite of stimulation. This introduces inhibitors as substances that reduce the rate of a reaction and students are challenged to use their general knowledge of enzymes to identify that inhibitors prevent the formation of the enzyme-substrate complex. Moving forwards, a quick quiz competition generates the abbreviation EIC (representing enzyme-inhibitor complex) and this introduces competitive inhibitors as substances that occupy the active site. The students are asked to apply their knowledge to a new situation to work out that these inhibitors have a similar shape to the enzyme’s substrate molecule. A series of exam-style questions are used throughout the lesson and at this point, the students are challenged to work out that an increase in the substrate concentration would reduce the effect of a fixed concentration of a reversible competitive inhibitor. The rest of the lesson focuses on non-competitive inhibitors and time is taken to ensure that key details such as the disruption of the tertiary structure is understood and biological examples are used to increase the relevance. Again, students will learn that increasing the concentration of the inhibitor results in a greater inhibition and a reduced rate of reaction but that increasing the substrate concentration cannot reduce the effect as was observed with competitive inhibitors.
Topic 5: Energy Flow, Ecosystems and the Environment (Edexcel International A-level Biology)
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Topic 5: Energy Flow, Ecosystems and the Environment (Edexcel International A-level Biology)

11 Resources
As the first topic to be taught at the start at the second year of the Edexcel International A-level Biology course, topic 5 is very important and the content includes the key reaction of photosynthesis. All 11 lessons included in this bundle are highly detailed and have been filled with a wide variety of tasks which will engage and motivate the students whilst covering the following specification points: The overall reaction of photosynthesis The phosphorylation of ADP and the hydrolysis of ATP The light-dependent reactions of photosynthesis The light-independent reactions of photosynthesis The products of the Calvin cycle The structure of the chloroplasts and the role of this organelle in photosynthesis The absorption spectrum and action spectrum Separating chloroplast pigments using chromatography and identifying them using retention factor values Be able to calculate net primary productivity Know the relationship between NPP, GPP and R Understand the meaning of the terms ecosystem, community, population and habitat The numbers and distribution of organisms in a habitat are controlled by biotic and abiotic factors The concept of niche The effect of temperature on the rate of enzyme activity and the calculation of the Q10 Isolation reduces gene flow and leads to allopatric and sympatric speciation If you would like to sample the quality of the lessons in this bundle, then download the products of photosynthesis and succession lessons as these have been uploaded for free
Cell structure & biological molecules (OCR A-level Biology A)
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Cell structure & biological molecules (OCR A-level Biology A)

19 Resources
It’s fair to say that cell structure and biological molecules are two of the most important topics in the OCR A-level Biology A course and all 19 lessons that are included in this bundle have been planned at length to cover the module 2.1.1 & 2.1.2 specification points in the detail required at this level. The lesson PowerPoints and their accompanying resources contain a wide range of tasks as well as regular checks to allow students to assess their understanding of the current content as well as prior knowledge checks to emphasise the importance of making links to topics in other modules. The following specification points in modules 2.1.1 (cell structure) and 2.1.2 (biological molecules) are covered by the lessons in this bundle: 2.1.1 The use of microscopy to observe and investigate different types of cell and cell structure in a range of eukaryotic organisms The use of the eyepiece graticule and stage micrometer The use of staining in light microscopy The use and manipulation of the magnification formula The difference between magnification and resolution The ultrastructure of eukaryotic cells and the functions of the different cellular components The interrelationship between the organelles involved in the production and secretion of proteins The importance of the cytoskeleton The similarities and differences between the ultrastructure of prokaryotic and eukaryotic cells 2.1.2 The properties and roles of water in living organisms The concept of monomers and polymers and the importance of condensation and hydrolysis reactions The chemical elements that make up biological molecules The structure and properties of glucose and ribose The synthesis and breakdown of a disaccharide and a polysaccharide by the formation and breakage of glycosidic bonds The structure of starch, glycogen and cellulose molecules The relationship between the structure, function and roles of triglycerides, phospholipids and cholesterol in living organisms The general structure of an amino acid The synthesis and breakdown of dipeptides and polypeptides The levels of protein structure The structure and function of globular proteins The properties and functions of fibrous proteins The key inorganic ions involved in biological processes The chemical tests for proteins, reducing and non-reducing sugars, starch and lipids If you would like to sample the quality of the lessons included in this bundle, then download the following lessons as they have been uploaded for free: The use of microscopy The importance of the cytoskeleton Properties and roles of water Glucose & ribose General structure of an amino acid Dipeptides, polypeptides and protein structure
The main stages of MEIOSIS (OCR A-level Biology A)
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The main stages of MEIOSIS (OCR A-level Biology A)

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This lesson describes the main stages of meiosis, focusing on the events which contribute to genetic variation and explains its significance in life cycles. The detailed PowerPoint and accompanying resources have been designed to cover points 2.1.6 (f) & (g) of the OCR A-level Biology A specification and includes description of crossing over, independent assortment, independent segregation and the production of haploid gametes In order to understand how the events of meiosis like crossing over and independent assortment and independent segregation can lead to variation, students need to be clear in their understanding that DNA replication in interphase results in homologous chromosomes as pairs of sister chromatids. Therefore the beginning of the lesson focuses on the chromosomes in the parent cell and this first part of the cycle and students will be introduced to non-sister chromatids and the fact that they may contain different alleles which is important for the exchange that occurs during crossing over. Time is taken to go through this event in prophase I in a step by step guide so that the students can recognise that the result can be new combinations of alleles that were not present in the parent cell. Moving forwards, the lesson explores how the independent assortment and segregation of chromosomes and chromatids during metaphase I and II and anaphase I and II respectively results in genetically different gametes. The key events of all of the 8 phases are described and there is a focus on key terminology to ensure that students are able to describe genetic structures in the correct context. The final part of the lesson looks at the use of a mathematical expression to calculate the possible combinations of alleles in gametes as well as in a zygote following the random fertilisation of haploid gametes. Understanding and prior knowledge checks are interspersed throughout the lesson as well as a series of exam-style questions which challenge the students to apply their knowledge to potentially unfamiliar situations. This lesson has been specifically planned to lead on from the previous two lessons on the cell cycle and the main stages of mitosis and constant references are made throughout to encourage students to make links and also to highlight the differences between the two types of nuclear division
Enzymes, biological membranes & cell division (OCR A-level Biology A)
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Enzymes, biological membranes & cell division (OCR A-level Biology A)

13 Resources
This lesson bundle has been formed from the 13 detailed lesson PowerPoints and their accompanying resources that have been uploaded to cover a lot of the content in modules 2.1.4, 2.1.5 and 2.1.6 of the OCR A-level Biology A specification. Each lesson contains a wide range of tasks, which include exam-style questions (with mark schemes), guided discussion points, and quick quiz competitions, that will engage and motivate the students whilst covering the following specification points: Module 2.1.4: Enzymes The role of enzymes in catalysing reactions that affect metabolism at a cellular and whole organism level The role of enzymes in catalysing both intracellular and extracellular reactions The mechanism of enzyme action The effect of pH on enzyme activity The effect of temperature on enzyme activity The calculation of the temperature coefficient The effect of enzyme and substrate concentration on enzyme activity The need for coenzymes, cofactors and prosthetic groups in some enzyme-controlled reactions Module 2.1.5: Biological membranes The fluid mosaic model of membrane structure and the roles of its components Simple and facilitated diffusion as forms of passive transport Active transport, endocytosis and exocytosis as processes requiring ATP as an immediate source of energy The movement of water across membranes by osmosis and the effects that solutions of different water potential can have on plant and animal cells Module 2.1.6: Cell division, cell diversity and cellular organisation The cell cycle How the cell cycle is regulated The main stages of mitosis The significance of mitosis in life cycles The significance of meiosis in life cycles The main stages of meiosis How cells of multicellular organisms are specialised for particular functions The organisation of cells into tissues, organs and organ systems The production of erythrocytes and neutrophils from stem cells in bone marrow If you would like to sample the quality of the lessons in this bundle, then download the following lessons as they have been uploaded for free: The roles of enzymes and mechanism of action Simple and facilitated diffusion Cell specialisation and organisation
Chi-squared test (AQA A-level Biology)
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Chi-squared test (AQA A-level Biology)

(1)
This lesson guides students through the use of the chi-squared test to determine the significance of the difference between observed and expected results. It is fully-resourced with a detailed PowerPoint and differentiated task worksheets that have been designed to cover the part of point 7.1 of the AQA A-level Biology specification which states that students should be able to use the test to compare the goodness of fit between the observed phenotypic ratios and expected ratios. The lesson has been written to include a step-by-step guide that demonstrates how to carry out the test in small sections. At each step, time is taken to explain any parts which could cause confusion and helpful hints are provided to increase the likelihood of success in exam questions on this topic. Students will understand how to use the phenotypic ratio to calculate the expected numbers and then how to find the critical value in order to compare it against the chi-squared value. A worked example is used to show the working which will be required to access the marks and then the main task challenges the students to apply their knowledge to a series of questions of increasing difficulty. This is the final lesson of topic 7.1 (inheritance) and links are made throughout the lesson to earlier parts of this topic such as dihybrid inheritance as well as to earlier topics such as meiosis.
Topic 8: The control of gene expression (AQA A-level Biology)
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Topic 8: The control of gene expression (AQA A-level Biology)

12 Resources
Each of the 12 lessons included in this bundle have been written to specifically cover the content as detailed in topic 8 of the AQA A-level Biology specification (The control of gene expression). The wide range of activities will maintain engagement whilst supporting the explanations of the biological knowledge to allow the students to build a deep understanding of this potentially difficult topic! Lessons which cover the following specification points are included in this bundle: Gene mutations and their effect on the structure of proteins Most of a cell’s DNA is not translated Totipotent, pluripotent, multipotent and unipotent stem cells Regulation of transcription by transcription factors The role of oestrogen in initiating transcription Epigenetic control of gene expression in eukaryotes Inhibition of transcription by increased DNA methylation or decreased acetylation of histones Translation of mRNA can be inhibited by RNA interference The main characteristics of benign and malignant tumours Determining the genome of simpler organisms to determine the proteome and its applications The development of DNA sequencing methods The production of DNA fragments through use of enzymes or a gene machine The role of the PCR to amplify DNA fragments The transfer of DNA into a host cell The use of labelled DNA probes to screen patients for heritable conditions, drug responses and to identify health risks VNTRs The technique of genetic fingerprinting to analyse DNA fragments If you would like to see the quality of the lessons, download the producing DNA fragments and DNA methylation and acetylation lessons as these have been uploaded for free
Aerobic energy system (OCR A-level PE)
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Aerobic energy system (OCR A-level PE)

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This detailed lesson describes the specific stages of the aerobic energy system and has been designed for the OCR A-level PE course. In line with the specification content in “Energy systems and ATP resynthesis”, the lesson describes the type of reaction, the sites of the specific stages within the system, the fuel used, the controlling enzymes, the ATP yield and the bi-products. The lesson begins by introducing the aerobic system as the system that becomes the dominant energy provider after the ATP-PC and glycolytic system. Students are challenged to recognise that this system supports lower intensity exercise but that it will support exercise for a much longer duration than the others, suggesting that it produces a high yield of ATP. The main part of the lesson looks at how this high yield of ATP is produced during glycolysis, the Krebs cycle and the electron transport chain and students will learn the location of each of these stages in the cell. Questions, discussion points and quiz competitions are included throughout the lesson and act as understanding checks to ensure that any misconceptions are addressed immediately. The final tasks of the lesson are a series of multiple choice questions and a quiz round called “UNLOCK THE AEROBIC SYSTEM SAFE” where the teams of students compete to recall the quantitative values associated with this topic.
Non-specific immune responses (Edexcel A-level Biology A)
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Non-specific immune responses (Edexcel A-level Biology A)

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This fully-resourced lesson describes the non-specific responses of the body to infection and includes details of phagocytosis, inflammation and interferon release. The engaging and detailed PowerPoint and accompanying resources have been primarily designed to cover the content of point 6.7 of the Pearson Edexcel A-level Biology A specification but topics including antigen-presentation are also introduced to prepare students for upcoming lessons on the immune response (6.8 & 6.9). At the start of the lesson, the students are challenged to recall that cytosis is a suffix associated with transport mechanisms and this introduces phagocytosis as a form of endocytosis which takes in pathogens and foreign particles. This emphasis on key terminology runs throughout the course of the lesson and students are encouraged to consider how the start or end of a word can be used to determine meaning. The process of phagocytosis is then split into 5 key steps and time is taken to discuss the role of opsonins as well as the fusion of lysosomes and the release of lysozymes. A series of application questions are used to challenge the students on their ability to make links to related topics including an understanding of how the hydrolysis of the peptidoglycan wall of a bacteria results in lysis. Students will be able to distinguish between neutrophils and monocytes from a diagram and at this point, the role of macrophages and dendritic cells as antigen-presenting cells is described so that it can be used in the next lesson. The importance of cell signalling for an effective immune response is discussed and the rest of the lesson focuses on the release of two chemicals - interferons and histamine. During the interferon section, references are made to a previous lesson on HIV structure and action so students can understand how the release of these signalling proteins helps neighbouring cells to heighten their anti-viral defences. A step by step guide is used to describe the release of histamine in the inflammatory response and the final task challenges students to use this support to form a detailed answer regarding the steps in inflammation.
Module 2.1.1: Cell structure (OCR A-level Biology A)
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Module 2.1.1: Cell structure (OCR A-level Biology A)

6 Resources
As cells are the building blocks of living organisms, and Biology is the study of life, it’s fairly obvious that a clear understanding of cell structure is going to be critical for the success of an A-level student on the OCR A-level Biology A course. The 6 lessons included in this bundle are highly detailed and have been intricately planned to contain the detail needed at this level and to make links to topics in the other modules of the specification. The lesson PowerPoints and accompanying resources contain a wide range of tasks which will engage and motivate the students whilst covering the following specification points in module 2.1.1: The use of microscopy to observe and investigate different types of cell and cell structure in a range of eukaryotic organisms The use of the eyepiece graticule and stage micrometer The use of staining in light microscopy The use and manipulation of the magnification formula The difference between resolution and magnification The ultrastructure of eukaryotic cells and the functions of the different cellular components The interrelationship between the organelles involved in the production and secretion of proteins The importance of the cytoskeleton The similarities and differences in the structure and ultrastructure of prokaryotic and eukaryotic cells If you would like to sample the quality of the lessons included in this bundle, then download “The use of microscopy” and “cytoskeleton” lessons as these have been uploaded for free
CITES and global biodiversity (Edexcel A-level Biology B)
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CITES and global biodiversity (Edexcel A-level Biology B)

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This lesson describes the effect that treaties such as CITES have had on global diversity. The PowerPoint and accompanying worksheets have been primarily designed to cover point 10.4 (ii) of the Edexcel A-level Biology B specification but has been planned to constantly challenge them on their knowledge of topic 3.3 (biodiversity) as a local conservation agreement is also considered Many hours of research have gone into the planning of this lesson to ensure that a range of interesting biological examples are included, with the aim of fully engaging the students in the material to increase its relevance. The students will learn that the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) was first agreed in 1973 and that 35000 species are currently found in appendix I, II or III. Time is taken to go through the meaning of each appendix and then the following animal and plant species are used to explain the finer details of the agreement: Tree pangolin, eastern black rhino for CITES appendix I Darwin’s orchid for CITES appendix II Four-horned antelope for CITES appendix III Exam-style questions are used to check on their understanding of the current topic as well as to challenge their knowledge of previously-covered topics such as the functions of keratin, when considering the structure of the rhino horn. Each of these questions has its own markscheme which is embedded in the PowerPoint and this allows the students to constantly assess their progress. The final part of the lesson considers the Countryside Stewardship Scheme as a local conservation agreements and discusses the reasons behind some of the key points. Students are told that farmers, woodland owners, foresters and land managers can apply for funding for a range of options including hedgerow management, low input grassland, buffer strips, management plans and soil protection options. The importance of the hedgerows for multiple species is discussed, and again a real-life example is used with bats to increase the likelihood of retention. The last task challenges them to use their overall knowledge of biodiversity to explain why buffer strips consisting of multiple types of vegetation are used and to explain why these could help when a farmer is using continuous monoculture.
Autoimmune diseases (OCR A-level Biology)
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Autoimmune diseases (OCR A-level Biology)

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This lesson describes why a disease would be deemed to be an autoimmune disease and describes the mechanisms involved in a few examples. The PowerPoint and accompanying worksheets have been primarily designed to cover point 4.1.1 (k) of the OCR A-level Biology A specification, but this lesson can also be used to revise the content of modules 2 and 3 and the previous lessons in 4.1.1 through the range of activities included The lesson begins with a challenge, where the students have to recognise diseases from descriptions and use the first letters of their names to form the term, autoimmune. In doing so, the students will immediately learn that rheumatoid arthritis, ulcerative colitis, type I diabetes mellitus, multiple sclerosis and myasthenia gravis are all examples of autoimmune diseases. The next part of the lesson focuses on the mechanism of these diseases where the immune system cells do not recognise the antigens (self-antigens) on the outside of the healthy cells, and therefore treats them as foreign antigens, resulting in the production of autoantibodies against proteins on these healthy cells and tissues. Key details of the autoimmune diseases stated above and lupus are described and links to previously covered topics as well as to future topics such as the nervous system are made. The students will be challenged by numerous exam-style questions, all of which have mark schemes embedded into the PowerPoint to allow for immediate assessment of progress.
Antibiotics
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Antibiotics

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An engaging lesson presentation and associated worksheet that looks at the use of antibiotics to treat bacterial infections and the raises the issue of the potential over-use of these substances. The lesson begins by getting the students to recognise the difference between three key terms that begin with anti (antibiotics, antivirals, antiseptics). Students will be introduced to the idea that antibiotics are specific to a small range of bacteria and therefore the correct one has to be selected before being prescribed. Moving forwards, students will meet the idea of the zone of inhibition and will understand how the size of this zone can be used as an indicator to the effectiveness of the treatment. Students are shown how to calculate the size of the zone and then are tested on their ability to apply this mathemetical knowledge. Finally, time is taken to look at the links to the topic of natural selection to explain how some bacteria are resistant to certain antibiotics. There are regular progress checks throughout the lesson so that students can assess their understanding. This lesson has been designed for GCSE students but could be used as an introduction with A-level Biology students who are about to begin the topic of immunity.