This fully-resourced lesson looks at the contribution of environmental and genetic factors to phenotypic variation. The engaging PowerPoint and accompanying worksheets have been designed to cover point 6.1.2 (a) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of how mutations and meiosis and the lack of availability of ions can cause variation within a species. Students are challenged at the start of the lesson to recognise the terms phenotype and species from their definitions in order to begin a discussion on the causes of the phenotypic variation within a species. Moving forwards, students will recall that mutations are the primary source of genetic variation and time is taken to look at the effect of gene and chromosome mutations. Gene mutations were covered earlier in module 6 so these tasks act as a prior knowledge check as students have to recognise the different types of gene mutations and explain their effects on the primary structure with reference to the genetic code. These prior knowledge checks are found throughout the lesson and challenge the knowledge of other topics that include photosynthesis and meiosis. The karyotype of an individual who has Down syndrome is used to introduce chromosome mutations and students will be introduced to the different types, with a focus on non-disjunction. The key events of meiosis that produce variation (crossing over and independent assortment) are explored and students will be given a mathematical formula to use to calculate the number of chromosome combinations in gametes and in the resulting zygote. The final part of the lesson looks at chlorosis and how an environmental factor can prevent the express of a gene. If you would like a lesson that goes into chromosome mutations in even greater detail, please search for the uploaded lesson on that topic which complements this lesson

This fully-resourced lesson has been designed to cover point 8.4 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification that states that students should know the structures and function of synapses in nerve impulse transmission. The majority of the lesson uses the cholinergic synapse as the example but other neurotransmitters are considered to provide the students with a wider view of this topic and to make links to specification point 8.15 The lesson begins by using a version of the WALL (as shown in the cover image) which asks the students to group 12 words into three groups of 4. Not only will this challenge their prior knowledge from topics earlier in this module but it will also lead to the discovery of four of the structures that are found in a synapse. Moving forwards, students are introduced to aectylcholine as the neurotransmitter involved at cholinergic synapses and they will start to add labels to the structures found in the pre-synaptic bulb. Time is taken to focus on certain structures such as the voltage gated channels as these types of channel were met previously when looking at the depolarisation of a neurone. There is plenty of challenge and discovery as students are pushed to explain why organelles like mitochondria would be found in large numbers in the bulb. With this process being a cascade of events, a bullet point format is used to ensure that the key content is taken in by the students and again key points like exocytosis and the action of acetylcholinesterase are discussed further. The final part of the lesson challenges the application aspect of the specification as students are introduced to unfamiliar situations in terms of synapses with new drugs like MDMA and are asked to work out and explain how these affect the nervous transmission. Understanding checks and prior knowledge checks are included throughout the lesson so that students can not only assess their progress against the current topic but also see whether they can make links to earlier topics.

This fully-resourced lesson guides students through the use of the Hardy-Weinberg equation to see whether a change in allele frequency is occurring in a population over time. The detailed PowerPoint and differentiated practice questions worksheets have been designed to cover point 4.5 (i) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification which expects students to be able to use this mathematical equation The lesson begins by looking at the equation and ensuring that students understand the meaning of each of the terms. The recessive condition, cystic fibrosis, is used as an example so that students can start to apply their knowledge and assess whether they understand which genotypes go with which term. Moving forwards, a step-by-step guide is used to show students how to answer a question. Tips are given during the guide so that common misconceptions and mistakes are addressed immediately. The rest of the lesson gives students the opportunity to apply their knowledge to a set of 3 questions, which have been differentiated so that all abilities are able to access the work and be challenged

This clear and concise lesson explores the importance of coenzymes in cellular respiration as detailed in point 5.2.2 (f) of the OCR A-level Biology A specification. Students encountered coenzymes in module 2.1.4 as well as looking at the roles of NAD, CoA and FAD whilst learning about glycolysis, the link reaction and Krebs cycle earlier in this module. Therefore this lesson was designed to check on their understanding of the importance of these roles and goes on to explain how the transport of the protons and electrons to the mitochondrial cristae is key for the production of ATP. This lesson has been written to tie in with the other uploaded lessons in module 5.2.2 which include the mitochondria, glycolysis, the link reaction and the Krebs cycle

This detailed lesson looks at each of the stages of aerobic respiration and explains how this reaction is a multi-stepped process where each step is controlled by an enzyme. The engaging PowerPoint and accompanying resource have been designed to cover points 7.3 (i) and (ii) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification. The lesson begins with an introduction to glycolysis and students will learn how this first stage of aerobic respiration is also the first stage when oxygen is not present. This stage involves 10 reactions and an opportunity is taken to explain how each of these reactions is catalysed by a different, specific intracellular enzyme. A version of “GUESS WHO” challenges students to use a series of structural clues to whittle the 6 organelles down to just the mitochondrion so that they can learn how the other three stages take place inside this organelle. Moving forwards, the key components of the organelle are identified on a diagram. Students are introduced to the stages of respiration so that they can make a link to the parts of the cell and the mitochondria where each stage occurs. Students will learn that the presence of decarboxylase and dehydrogenase enzymes in the matrix along with coenzymes and oxaloacetate allows the link reaction and the Krebs cycle to run and that these stages produce the waste product of carbon dioxide. Finally, time is taken to introduce the electron transport chain and the enzyme, ATP synthase, so that students can begin to understand how the flow of protons across the inner membrane results in the production of ATP and the atmospheric oxygen being reunited with hydrogen.

This fully-resourced lesson looks at the internal and external structure of the mammalian heart and uses the human heart to represent this anatomy. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 3.1.2 (e) (i) of the OCR A-level Biology A specification As this topic was covered at GCSE, the lesson has been planned to build on this prior knowledge whilst adding the key details which will enable students to provide A-level standard answers. The primary focus is the identification of the different structures of the heart but it also challenges their ability to recognise the important relationship to function. For example, time is taken to ensure that students can explain why the atrial walls are thinner than the ventricular walls and why the right ventricle has a thinner wall than the left ventricle. Opportunities are taken throughout the lesson to link this topic to the others found in topic 3.1.2 including those which have already been covered like circulatory systems as well as those which are upcoming such as the initiation of heart action. There is also an application question where students have to explain why a hole in the ventricular septum would need to be repaired if it doesn’t naturally close over time.

This fully-resourced REVISION lesson has been written to challenge the students on their knowledge of the content of topic 8 (Transport in mammals) of the CIE International A-level Biology specification. The engaging PowerPoint and accompanying resources will motivate the students whilst they assess their understanding of the content and identify any areas which may require further attention. The wide range of activities have been written to cover as much of the topic as possible but the following specification points have been given particular focus: The significance of the oxygen dissociation curves at different concentrations of carbon dioxide (The Bohr effect) The role of haemoglobin in carrying oxygen The role of haemoglobin in carrying carbon dioxide Draw the structures of red blood cells, neutrophils, monocytes and lymphocytes The relationship between the structure and function of a capillary The internal structure of the heart and its associated blood vessels Explain how heart action is initiated and controlled The pressure changes of the cardiac cycle The relationship between the structure and function of arteries and veins The double, closed circulatory system of a mammal Quiz rounds such as “Does this FLOW correctly” and “YOU DO THE MATH” are used to test the students on the finer details of their knowledge of the blood vessels and numerical facts

This fully-resourced revision lesson has been written to cover the major details of the electricity and circuits topic that can be assessed in the GCSE Physics and Combined Science (HT) exams. The engaging PowerPoint and accompanying resources contain a wide range of activities which include exam-style questions with clearly explained answers, differentiated tasks and quiz competitions to allow students to assess their understanding and to ultimately recognise those areas which need further consideration. The following points are covered in this revision lesson: The electrical symbols that represent the electrical components Describe the differences between series and parallel circuits Recall that a voltmeter is connected in parallel One volt is equal to one joule per coulomb Recall and use the equations that calculate energy transferred, charge, potential difference, power and electrical power Recall that an ammeter is connected in series Calculate the currents, potential differences and resistances in series and parallel circuits Explain how current varies with potential difference in resistors Know the functions of the wires in a plug and the safety features The main task of the lesson, which challenges the students to calculate the currents, potential differences and resistances in series and parallel circuits, is differentiated to allow students of differing abilities to access the work

This revision lesson is fully-resourced and differentiated to allow students of differing abilities to assess their understanding of topic 2.4 (Further motion concepts) of the WJEC GCSE Physics specification. The engaging and detailed PowerPoint and accompanying resources contain exam-style questions, quick tasks, discussion points and a quiz competition which check on the following specification points: The qualitative relationship between mass and velocity in the calculation of momentum Application of the law of the conservation of momentum to perform calculations involving collisions Applying the kinetic energy equation to compare the size of this energy store before and after an interaction Newton’s second law in the form force = change in momentum over time Using equations to model the motion of an object The principle of moments To fall in line with the specification, there is a big emphasis on mathematical skills in this lesson and students are given guidance and assistance to ensure that they can access the work

This fully-resourced lesson looks at the structure of genes and explores their role as a base sequence on DNA that codes for the amino acid sequence of a polypeptide. Both the PowerPoint and accompanying resource have been designed to cover the second part of point 4.1 of the AQA A-level Biology specification and has been written to specifically tie in with the previous lesson on DNA in prokaryotes and eukaryotes. The lesson begins with a prior knowledge check as the students have to recognise the key term chromosome from a description involving DNA and histones. This allows genes, as sections of a chromosome, to be introduced and the first of a number of quiz rounds is then used to get the students to meet the term locus so that they can understand how each gene has a specific location on a chromosome. Whenever possible, opportunities are taken to make links to the other parts of the AQA specification and this is utilised here as students are reminded that alternative versions of a gene (alleles) can be found at the locus. Moving forwards, students will learn that 3 DNA bases is a triplet and that each triplet codes for a specific amino acid. At this point, the genetic code is introduced and students are challenged to explain how the code contains 64 different triplets. By comparing this number against the number of different amino acids in proteins, students will see how each amino acid is encoded for by more than one triplet and how this explains the degenerate nature of the genetic code. Again, an opportunity is taken to link to gene mutations. Finally, the students are told that most of the nuclear DNA in a eukaryote doesn’t code for a polypetptide and that even within a gene, there are coding and non-coding regions known as exons and introns respectively. The last section of the lesson uses a quiz round to check on all of the key terms which have been met in the two lessons on DNA, genes and chromosomes.

This engaging lesson covers the biological classification of a species, phylogenetic classification and the use of the binomial naming system. The PowerPoint and accompanying resources have been designed to cover point 4.5 of the AQA A-level Biology specification which is titled species and taxonomy. The lesson begins by looking at the meaning of a population in Biology so that the term species can be introduced. A hinny, which is the hybrid offspring of a horse and a donkey, is used to explain how these two organisms must be members of different species because they are unable to produce fertile offspring. Although the art of courting might be lost on humans in the modern world, the marabou stork is used as an example to show how courtship behaviour is an essential precursor to successful mating in most organisms. Students are encouraged to discuss other examples of courtship behaviour, such as the release of pheromones and birdsong, so that their knowledge and understanding is broad. Moving forwards, students will learn that species is the lowest taxon in the modern-day classification hierarchy. A quiz runs throughout the lesson and this particular round will engage the students whilst they learn the names of the other 7 taxa and the horse and the donkey from the earlier example are used to complete the hierarchy. Students will understand that the binomial naming system was introduced by Carl Linnaeus to provide a universal name for each species and they will be challenged to apply their knowledge by completing a hierarchy for a modern-day human, by spotting the correct name for an unfamiliar organism and finally by suggesting advantages of this system. The final part of the lesson briefly looks at how advances in genome sequencing and the comparison of common biological molecules has allowed the relationships between organisms to be clarified. This is a detailed lesson and it is estimated that it will take around 2 hours of A-level teaching time to cover the content and therefore this specification point.

This lesson looks at the detailed structure of DNA and builds on the knowledge from topic 1 to explain how this nucleic acid differs in the nucleus, mitochondria and chloroplasts of eukaryotic cells and in prokaryotic cells. Both the engaging PowerPoint and accompanying resources have been designed to cover the first part of point 6.1 (b) of the CIE International A-level Biology specification. As well as focusing on the differences between the DNA found in these two types of cells which includes the length, shape and association with histones, the various tasks will ensure that students are confident to describe how this double-stranded polynucleotide is held together by hydrogen and phosphodiester bonds. These tasks include exam-style questions which challenge the application of knowledge as well as a few quiz competitions to maintain engagement.

This fully-resourced lesson explains how gel electrophoresis is used to analyse nucleic acids and proteins and explores its applications in forensic science and medical diagnosis. The engaging and detailed PowerPoint and accompanying resource have been written to cover point 19.1 (d) of the CIE International A-level Biology specification As a whole lesson, each step of the genetic fingerprinting process is covered but with the main focus on gel electrophoresis within this process. Students will be introduced to STRs and will come to recognise their usefulness in human identification as a result of the variability between individuals. Moving forwards, the involvement of the PCR and restriction enzymes are discussed and students are challenged on their knowledge of this process and these substances as they were encountered in a previous lesson. The main section of the lesson focuses on the use of gel electrophoresis to separate DNA fragments (as well as proteins) and the key ideas of separation due to differences in base pair length or molecular mass are discussed and explained. As well as current understanding checks, an application question involving Huntington’s disease is used to challenge their ability to apply their knowledge of the process to an unfamiliar situation. The remainder of the lesson describes how the DNA is transferred to a membrane and hybridisation probes are used to create a pattern on the X-ray film. Time has been taken to make continuous links to the previous lessons in topic 19.1 as well as those from topic 6 where DNA, RNA and protein synthesis were introduced.

This is a fully-resourced revision lesson that has been written to challenge students on their knowledge and understanding of the PAPER 2 topics. The range of tasks will prepare the students to answer the range of questions that they may encounter on topics B1 and B6 - B9 as detailed in the Pearson Edexcel GCSE Combined Science specification. The lesson has been designed to take place on the PAPER 2 HIGH STREET and the tasks include exam-style questions with displayed mark schemes, engaging quiz competitions and discussion points to allow the following points to be covered: Eukaryotic vs Prokaryotic cells Converting between units of size The structures of the animal and plant cells The structure of the human heart Calculating the surface area to volume ratio Adaptations of the gas exchange system The blood vessels associated with the human heart Calculating the cardiac output The features of the root hair cell to allow for absorption The nitrogen cycle The relationship between the rate of photosynthesis and light intensity and distance Using the inverse square law calculation Temperature and photosynthesis The regulation of blood glucose by the release of insulin and glucagon Diabetes type I and II Calculating the BMI The interaction of the reproductive hormones in the menstrual cycle IVF as assisted reproductive technology The hormonal and barrier methods of contraception Eutrophication as a negative human interaction in an ecosystem The carbon cycle In order to cater for the range of abilities that can be found in Combined Science classes, most of the tasks have been differentiated. There are also a number of step by step guides to demonstrate how to tackle some of the more difficult concepts including the mathemetical elements If you would like to see the quality of these revision lessons, download the PAPER 1 REVISION LESSON which has been shared for free

This fully-resourced lesson has been written to prepare students for the range of mathematical-based questions that they may face on the two OCR GCSE Chemistry papers. The lesson has been designed to contain a wide range of activities which includes 8 quiz competition rounds spread across the duration of the lesson to maintain engagement whilst the students assess their understanding. The mathematical skills covered in this lesson include: Calculating the number of sub-atomic particles in atoms and ions Writing chemical formulae for ionic compounds Identifying isotopes Using Avogadro’s constant to calculate the number of particles Calculating the relative formula mass Calculating amount in moles using the mass and the relative formula mass Balancing chemical symbol equations Calculating reacting masses Gas calculations using molar volume Calculating concentration of solutions Titration calculations Deducing the empirical formula Calculating energy changes in reactions Most of the resources have been differentiated two ways to allow students of differing abilities to access the work whilst still being challenged. In addition, step by step guides are used to demonstrate how to carry out some of the more difficult calculations such as the harder mole calculations and calculating masses in reactions This lesson could be used with higher ability students on the OCR GCSE Combined Science course by taking out the sections which are not applicable.

This detailed lesson describes how aerobic glycolysis, the Krebs cycle and the electron transport chain produce energy for sport and exercise. The engaging PowerPoint and accompanying resource have been designed to cover the 4th part of point A7 in UNIT 1 of the Pearson BTEC Level 3 National Diploma in Sport and Exercise Science specification which states that students should understand how these stages produce energy as well as the role of the mitochondria. The lesson has been written to include a wide range of tasks which include exam-style questions and discussion points to check on understanding and quiz competitions to introduce key terms and values in a memorable way and to maintain engagement and motivation. There is a focus on the link between each stage and the next and the location in a cell where each one occurs. Due to the extensiveness of this lesson, it is estimated that it will take in excess of 2 teaching hours to cover the detail within this resource