A detailed lesson presentation (37 slides) and associated worksheets that looks at the different pieces of evidence that scientists use to support evolution and discusses how these support the theory. The lesson begins by challenging students to decide which piece of evidence is the key piece in supporting evolution (fossils). Students will then have to arrange a number of statements to describe how a fossil is formed. Students are introduced to the fossil record and questions are used to check that they understand where the oldest fossils would be found. Moving forwards, students are given three pieces of evidence that would be observed in the fossil record and they are challenged to explain how each of these supports the theory of evolution. Quick competitions are then used to get the students to see some extinct organisms in the Dodo and Woolly Mammoth and again they are questioned on how extinct animals support the theory of evolution. Further evidence in rapid changes in species and molecular comparison is discussed. There are regular progress checks throughout the lesson so that students can assess their understanding and there is a set homework included.

This is a detailed, engaging and fully-resourced REVISION LESSON which allows students of all abilities to assess their understanding of the content in module 2.1.3 (Nucleotides and nucleic acids) of the OCR A-level Biology A specification. Considerable time has been taken to design the lesson to include a wide range of activities to motivate the students whilst they evaluate their knowledge of DNA, RNA and the roles of these nucleic acids in DNA replication and protein synthesis. Most of the tasks have been differentiated so that students of differing abilities can access the work and move forward as a result of the tasks at hand. This lesson has been planned to cover as much of the specification as possible but the following sub-topics have received particular attention: The structure of DNA Phosphorylated nucleotides DNA replication Transcription and translation Gene mutations and their affect on the primary structure of a polypeptide The structure of RNA In addition to a focus on the current topic, links are made throughout the lesson to other topics such as the journey of an extracellular protein following translation and the cell cycle. If you like the quality of this revision lesson, please look at the other uploaded revision lessons for this module and for this specification

An engaging lesson presentation (74 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within the Biology unit B6 (Inheritance, variation and evolution) of the AQA GCSE Combined Science specification (specification unit 4.6). The topics that are tested within the lesson include: Sexual and asexual reproduction Meiosis DNA and the genome Genetic inheritance and disorders Sex determination Variation Genetic engineering Resistant bacteria Classification of living organisms Students will be engaged through the numerous activities including quiz rounds like “From Numbers 2 LETTERS” and “This shouldn’t be too TAXing” whilst crucially being able to recognise those areas which need further attention

An engaging lesson presentation (61 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B2 (Organisation) of the AQA GCSE Biology specification (specification point 4.2) The topics that are tested within the lesson include: Principles of organisation The human digestive system The heart and blood vessels Blood Coronary heart disease The effect of lifestyle on some non-communicable diseases Plant organ systems Students will be engaged through the numerous activities including quiz rounds like “SPOT the SUBSTANCE" and “Where’s LENNY” whilst crucially being able to recognise those areas which need further attention

An engaging lesson presentation (56 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within Topic 6 (Plant structures and their function) of the EDEXCEL GCSE Biology specification The topics that are tested within the lesson include: Photosynthesis and producers The reaction of photosynthesis Limiting factors The structure of root hair cells The structure of the xylem and phloem The effect of environmental factors on the rate of transpiration Students will be engaged through the numerous activities including quiz rounds like “XYLEM vs PHLOEM" and “Shine the LIGHT on any ERRORS” whilst crucially being able to recognise those areas which need further attention

An engaging lesson presentation (68 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within the Biology topic B4 (Bioenergetics) of the AQA GCSE Combined Science specification (specification unit B4.4). The topics that are tested within the lesson include: Photosynthesis reaction Rate of photosynthesis Uses of glucose from photosynthesis Aerobic respiration Anaerobic respiration Response to exercise Students will be engaged through the numerous activities including quiz rounds like “Take a STEP back” and “Shine a LIGHT on the errors” whilst crucially being able to recognise those areas which need further attention

This fully-resourced REVISION LESSON has been designed to provide the students with numerous opportunities to assess their understanding of the content of module 5.2.2 (Respiration) of the OCR A-level Biology A specification. The importance of this metabolic reaction is obvious and this is reflected in the volume of questions in the terminal exams which require an in depth knowledge of the stages of both aerobic and anaerobic respiration. The lesson contains a wide range of activities that cover the following points of the specification: Glycolysis as a stage of aerobic and anaerobic respiration The use and production of ATP through respiration Anaerobic respiration in mammalian muscle tissue The stages of aerobic respiration that occur in the mitochondrial matrix Oxidative phosphorylation The use of respirometers Calculating the respiratory quotient value for different respiratory substrates Revision lessons which cover the other sub-modules of module 5 are uploaded and tie in well with this content

A whole lesson on the topic of active transport which includes a concise lesson presentation (20 slides) and a set of questions that are used to check on the students’ understanding. This lesson is designed for GCSE students (14 - 16 year olds in the UK) but could be used with A-level students who are covering the topic of movement across cell membranes. The main focus of the lesson is to get students to understand that this is an active process which moves substances against the concentration gradient and therefore needs energy for this process. The final part of the lesson looks at the different types of questions that can accompany this topic and a step-by-step guide is used to answer a difficult longer answer question as a class.

This is a fully-resourced revision lesson that includes a detailed and engaging powerpoint (81 slides) that uses a combination of exam questions, understanding checks, quick differentiated tasks and quiz competitions to enable students to assess their understanding of the content found within Topic 8 (Grey Matter) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification. The specification points that are tested within the lesson include: Know the structure and function of sensory, relay and motor neurones including the role of Schwann cells and myelination. Understand how the nervous systems of organisms can cause effectors to respond to a stimulus. Understand how the pupil dilates and contracts. Understand how a nerve impulse (action potential) is conducted along an axon including changes in membrane permeability to sodium and potassium ions and the role of the myelination in saltatory conduction. Know the structure and function of synapses in nerve impulse transmission, including the role of neurotransmitters, including acetylcholine. Understand how IAA bring about responses in plants to environmental cues Know the location and functions of the cerebral hemispheres, hypothalamus, cerebellum and medulla oblongata in the human brain. Understand how magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), positron emission tomography (PET) and computed tomography (CT) scans are used in medical diagnosis and the investigation of brain structure and function. Understand how imbalances in certain, naturally occurring brain chemicals can contribute to ill health, including dopamine in Parkinson’s disease and serotonin in depression, and to the development of new drugs. Understand the effects of drugs on synaptic transmissions, including the use of L-Dopa in the treatment of Parkinson’s disease and the action of MDMA in Ecstasy. Students will be engaged by the numerous quiz rounds such as “From NUMBERS 2 LETTERS” and “COMMUNICATE the WORD” whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual A-level terminal exams

This is a fully-resourced REVISION lesson that consists of an engaging PowerPoint (87 slides) and associated worksheets that challenge the students on their knowledge of the content of Topic 1 (Lifestyle, Health and Risk) of the Edexcel A-Level Biology A (Salters-Nuffield) specification. A wide range of activities have been written into the lesson to maintain motivation and these tasks include exam questions (with answers), understanding checks, differentiated tasks and quiz competitions. The lesson has been designed to include as much which of the content from topic 1, but the following specification points have been given particular attention: The differences between monosaccharides, disaccharides and polysaccharides, including glycogen and starch (amylose and amylopectin). Be able to relate the structures of monosaccharides, disaccharides and polysaccharides to their roles in providing and storing energy Know how monosaccharides join to form disaccharides (sucrose, lactose and maltose) and polysaccharides (glycogen and amylose) through condensation reactions forming glycosidic bonds, and how these can be split through hydrolysis reactions. Know how a triglyceride is synthesised by the formation of ester bonds during condensation reactions between glycerol and three fatty acids. Understand the course of events that leads to atherosclerosis Know how factors such as genetics, diet, age, gender, high blood pressure, smoking and inactivity increase the risk of cardiovascular disease Know the benefits and risks of treatments for CVD Understand the blood-clotting process and its role in CVD Understand how the structures of arteries and veins) relate to their functions. Understand the importance of water as a solvent in transport, including its dipole nature. This lesson can be used at numerous points over the duration of the course, as an end of topic revision aid, in the lead up to the mocks or in the lead up to the actual A-level exams.

This revision resource has been designed to include a range of activities such as exam questions, understanding checks and quiz competitions which will motivate the students whilst they assess their understanding of the content found in module 2.1.4 (Enzymes) of the OCR A-level Biology A specification. The resource includes a detailed and engaging Powerpoint (70 slides) and associated worksheets The range of activities have been designed to cover as much of the content as possible but the following sub-topics have been given particular attention: The role of enzymes as biological catalysts that lower the activation energy The lock and key theory and the induced fit hypotheses The mechanism of enzyme action to include the tertiary structure The effect of inhibitors on the rate of enzyme-controlled reactions The effect of pH on the rate of reaction Coenzymes and cofactors The idea of an optimum temperature and explaining the decrease in rate when temperatures increase or decrease Calculating the temperature coefficient In addition to these topics, some topics from other modules such as the PCR and precursor molecules are tested in order to challenge the students on their ability to make links between the modules.

This resource, which consists of an engaging and detailed PowerPoint and a differentiated worksheet, has been designed to cover the content in the supplement section of topic 14.4 in the CIE IGCSE Biology specification, specifically the control of blood glucose concentration and the symptoms and treatment of diabetes type I. A wide range of activities are found across the lesson which will engage and motivate the students whilst the important content is covered and understanding and previous knowledge checks are included at regular points so students can assess their progress. The following content is covered across this resource: The release of insulin by the pancreas when high glucose levels are detected The role of the liver and muscle cells in the conversion of glucose to glycogen Negative feedback in this homeostatic control mechanism Diagnosis and treatment of type I diabetes Type I diabetes as an autoimmune disease (link to topic 10) The release of glucagon and the role of the liver cells when blood glucose concentration is low As shown above, links are made to other topics where possible so students can recognise the importance of making connections between related subjects. This lesson has been designed for students studying on the CIE IGCSE Biology course but is suitable for older students who are looking at this topic at A-level and need to recall the key details

This lesson has been designed to cover the content of the 1st part of specification point 6.1.2 of the AQA A-level Biology specification which states that students should know the basic structure of a Pacinian corpuscle and be able to use its function as a representation of sensory receptors. By the end of the lesson students will understand that sensory receptors respond to specific stimuli and how a generator potential is established. The lesson begins by using a quiz to get the students to recognise the range of stimuli which can be detected by receptors. This leads into a task where the students have to form 4 sentences to detail the stimuli which are detected by certain receptors and the energy conversion that happen as a result. Students will be introduced to the idea of a transducer and learn that receptors always convert to electrical energy which is the generator potential. The remainder of the lesson focuses on the Pacinian corpuscle and how this responds to pressure on the skin. The involvement of sodium and potassium ions is introduced so discussions on how the membrane potential changes from resting potential in the establishment of a generator potential are encouraged. This lesson has been written for students studying on the AQA A-level Biology course and ties in nicely with other uploaded lessons which cover the content of topic 6

This concise lesson covers the content of specification point 5.1.5 (l) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of the action of neuromuscular junctions. Due to a number of similarities between these structures and cholinergic synapses, this lesson uses prior knowledge of these connections between neurones to build a good understanding of the junctions. Students will discover that the events that occur at an axon tip mirror those which happen at the pre-synaptic bulb and this is then developed to look at the differences in terms of the events once the acetylcholine has bound to its receptor sites. There is a focus on the structure of the sarcolemma and time is taken to explain how the action potential is passed from this membrane to the transverse tubules in order to stimulate the release of calcium ions from the sarcoplasmic reticulum. As a result, this lesson ties in nicely with the following lesson on the contraction of skeletal muscle and students will be able to link the binding to troponin in that lesson to the release of these ions from this lesson. Both of the main tasks of the lesson have been differentiated so that students of all abilities can access the work and make progress. This lesson has been designed for those students studying on the OCR A-level Biology course and ties in nicely with the other uploaded lessons on module 5.1.5 (Animal and plant responses)

This lesson has been written to cover the part of specification point 6.4.3 of the AQA A-level Biology specification which states that students should be able to describe how water and glucose are reabsorbed in the proximal convoluted tubule. It has specifically been designed to build on the knowledge gained in the previous lessons on the structure of the nephron and ultrafiltration. The lesson begins by challenging the students to recall the substances that are found in the glomerular filtrate so that each of them can be considered over the course of the rest of the lesson. Moving forwards, the first of the numerous discussion points which are included in the lesson is used to get students to predict the component of the filtrate which won’t be found in the urine when they are presented with pie charts from each of these situations. Upon learning that glucose is 100% reabsorbed, along with most of the ions and some of the water, the rest of the lesson focuses on describing the relationship between the structure of the PCT and the function of selective reabsorption. Again, this section begins by encouraging the students to discuss and to predict which structures they would expect to find in a section of the kidney if the function is to reabsorb. They are given the chance to see the structure (as shown in the cover image) before each feature is broken down to explain its importance. Time is taken to look at the role of the cotransporter proteins to explain how this allows glucose, along with sodium ions, to be reabsorbed from the lumen of the PCT into the epithelial cells. The final part of the lesson focuses on urea and how the concentration of this substance increases along the tubule as a result of the reabsorption of some of the water. This lesson has been designed for students studying on the AQA-A level Biology course and ties in nicely with the other lessons from 6.4.3 as well as the other uploaded lessons from topic 6

This engaging and fully-resourced lesson looks at the myogenic nature of cardiac muscle and explores the roles of the SAN, AVN and Purkyne tissue in the initiation and control of heart action. The PowerPoint and accompanying resources have been designed to cover points 8.2 (d) of the CIE International A-level Biology specification. The lesson begins with the introduction of the SAN as the natural pacemaker and then time is given to study each step of the conduction of the impulse as it spreads away from the myogenic tissue in a wave of excitation. The lesson has been written to make clear links to the cardiac cycle and the structure of the heart and students are challenged on their knowledge of this system from topic 8.1. Moving forwards, students are encouraged to consider why a delay would occur at the AVN and then they will learn that the impulse is conducted along the Bundle of His to the apex so that the contraction of the ventricles can happen from the bottom upwards. The structure of the cardiac muscle cells is discussed and the final task of the lesson challenges the students to describe the conducting tissue, with an emphasis on the use of key terminology Due to the detailed nature of this lesson, it is estimated that it will take about 2 hours of A-level teaching time to cover the detail

This fully-resourced lesson looks at the double, closed circulatory system as found in a mammal and considers how the pulmonary circulation differs from the systemic circulation. The engaging PowerPoint and accompanying resources have been designed to cover point 8.1 (a) of the CIE International A-level Biology specification The lesson begins with a focus on the meaning of a double circulatory system and checks that students are clear in the understanding that the blood passes through the heart twice per cycle of the body. Beginning with the pulmonary circulation, students will recall that the pulmonary artery carries the blood from the right ventricle to the lungs. An opportunity is taken at this point to check on their knowledge of inhalation and the respiratory system as well as the gas exchange between the alveoli and the capillary bed. A quick quiz is used to introduce arterioles and students will learn that these blood vessels play a crucial role in the changes in blood pressure that prevent the capillaries from damage. When looking at the systemic circulation, time is taken to look at the coronary arteries and renal artery as students have to be aware of these vessels in addition to the ones associated with the heart. In the final part of the lesson, students are challenged to explain how the structure of the heart generates a higher pressure in the systemic circulation and then to explain why the differing pressures are necessary. As a result of the constant reference to the heart, the blood vessels and the blood, students will be reminded that these are the components of the circulatory system

This fully-resourced looks at the phenomenon known as the Bohr effect and describes and explains how an increased carbon dioxide concentration effects the dissociation of adult oxyhaemoglobin. The PowerPoint and accompanying resources have been designed to cover point 8.1 (g) of the CIE International A-level Biology specification and continually ties in with the previous lesson on the role of haemoglobin in carrying oxygen. The lesson begins with a terminology check to ensure that the students can use the terms affinity, oxyhaemoglobin and dissociation. In line with this, they are challenged to draw the oxyhaemoglobin dissociation curve and are reminded that this shows how oxygen associates with haemoglobin but how it dissociates at low partial pressures. Moving forwards, a quick quiz is used to introduce Christian Bohr and the students are given some initial details of his described effect. This leads into a series of discussions where the outcome is the understanding that an increased concentration of carbon dioxide decreases the affinity of haemoglobin for oxygen. The students will learn that this reduction in affinity is a result of a decrease in the pH of the cell cytoplasm which alters the tertiary structure of the haemoglobin. Opportunities are taken at this point to challenge students on their prior knowledge of protein structures as well as the bonds in the tertiary structure. The lesson finishes with a series of questions where the understanding and application skills are tested as students have to explain the benefit of the Bohr effect for an exercising individual.