This lesson introduces the three-domain system and describes some of the biochemical methods used in classification to overcome the problems of morphological convergence. The PowerPoint and accompanying resources have been designed to cover points [c] and [e] in AS unit 2, topic 1 of the WJEC A-level Biology specification The lesson begins with an introduction of Carl Woese and goes on to describe how he is most famous for his definition of the Archaea as a new domain of life. Students were introduced to domains and the other classification taxa in a previous lesson, so their recall of this knowledge is continually tested and built upon as details are added. Students will discover the key differences between Archaea and Bacteria that led to the splitting of the prokaryotae kingdom and the addition of this higher classification rank. Moving forwards, the rest of the lesson considers other molecules that can be compared between species for classification purposes and the primary structure of cytochrome is described and discussed. At this point in the lesson, the students are also tested on their knowledge of the nature of the genetic code and have to explain how mutations to DNA can also be used for comparative purposes. The use of DNA genetic fingerprinting is briefly introduced and this is described in greater detail in a future lesson about assessing biodiversity at a molecular level

This lesson describes the international and local conservation agreements that are made to protect species and habitats. The detailed PowerPoint and accompanying worksheets have been designed to cover point 4.2.1 (i) of the OCR A-level Biology A specification and includes details of CITES, CBD and CSS. Many hours of research have gone into the planning of this lesson to ensure that a range of interesting biological examples are included, with the aim of fully engaging the students in the material to increase its relevance. Beginning with the Convention on International Trade in Endangered Species of Wild Fauna and Flora, the students will learn that this was first agreed in 1973 and that 35000 species are currently found in appendix I, II or III. Time is taken to go through the meaning of each appendix and then the following animal and plant species are used to explain the finer details of the agreement: Tree pangolin, eastern black rhino for CITES appendix I Darwin’s orchid for CITES appendix II Four-horned antelope for CITES appendix III Exam-style questions are used to check on their understanding of the current topic as well as to challenge their knowledge of previously-covered topics such as the functions of keratin, when considering the structure of the rhino horn. Each of these questions has its own markscheme which is embedded in the PowerPoint and this allows the students to constantly assess their progress. Moving forwards, the Rio Convention on Biological Diversity is introduced and students will understand that this is a key document regarding sustainable development. The final part of the lesson considers local conservation agreements, focusing on the Countryside Stewardship Scheme and its replacement, the Environmental Stewardship Scheme. Students are told that farmers, woodland owners, foresters and land managers can apply for funding for a range of options including hedgerow management, low input grassland, buffer strips, management plans and soil protection options. The importance of the hedgerows for multiple species is discussed, and again a real-life example is used with bats to increase the likelihood of retention. The last task challenges them to use their overall knowledge of module 4.2.1 (biodiversity) to explain why buffer strips consisting of multiple types of vegetation are used and to explain why these could help when a farmer is using continuous monoculture.

This lesson discusses how biodiversity may be considered at different levels and describes how to calculate Simpson’s Index of diversity. The PowerPoint and accompanying worksheets have primarily been designed to cover points 4.2.1 (a, c and d) of the OCR A-level Biology A specification but also make links to the upcoming topics of classification, natural selection and adaptations A quiz competition called BIOLOGICAL TERMINOLOGY SNAP runs over the course of the lesson and this will engage the students whilst challenging them to recognise species, population, biodiversity, community and natural selection from their respective definitions. Once biodiversity as the variety of living organisms in a habitat is revealed, the students will learn that this can relate to a range of habitats, from those in the local area to the Earth. Moving forwards, the students will begin to understand that biodiversity can be considered at a range of levels which include within a habitat, within a species and within different habitats so that they can be compared. Species richness as a measure of the number of different species in a community is met and a biological example in the rainforests of Madagascar is used to increase its relevance. However, students will also be introduced to species evenness and will learn that in order for a habitat to be deemed to be biodiverse, it must be both species rich and even. The students are introduced to an unfamiliar formula that calculates the heterozygosity index and are challenged to apply their knowledge to this situation, as well as linking a low H value to natural selection. The rest of the lesson focuses on the calculation of Simpson’s Index of diversity and a 4-step guide is used to walk students through each part of the calculation. This is done in combination with a worked example to allow students to visualise how the formula should be applied to actual figures. Using the method, they will then calculate a value of D for a comparable habitat to allow the two values to be considered and the significance of a higher value is explained. All of the exam-style questions have mark schemes embedded in the PowerPoint to allow students to continuously assess their progress and understanding.

This detailed lesson describes the absorption of water, the movement through the root and the role of the endodermis. Both the PowerPoint and accompanying resource have been designed to cover specification points (j, k & l) in topic 3 of AS unit 2 of the WJEC A-level Biology specification and includes descriptions of the apoplast, symplast and vacuolar pathways and the Casparian strip. The lesson begins by looking at the specialised features of the root hair cell so that students can understand how these epidermal cells absorb water and mineral ions from the soil. Moving forwards, students are introduced to key terminology such as epidermis and root cortex before time is taken to look at the different pathways that water and minerals use to transverse across the cortex. Discussion points are included throughout the lesson to encourage the students to think about each topic in depth and challenges them to think about important questions such as why the apoplast pathway is needed for the water carrying the ions. The main part of the lesson focuses on the role of the endodermis in the transport of the water and ions into the xylem. Students will be introduced to the Casparian strip and will learn how this layer of cells blocks the apoplast pathway. A step by step method using class questions and considered answers is used to guide them through the different steps and to support them when writing the detailed description. This lesson has been written to tie in with the next lesson on the pathways and mechanisms by which water and mineral ions are transported to the leaves.

This lesson describes the movement of water from the root to the leaf and includes the transpiration stream and the cohesion-tension theory. The PowerPoint and accompanying resources have been designed to cover point (n) of topic 3 in AS unit 2 of the WJEC A-level Biology specification This lesson has been written to follow on from a previous lesson, which finished with the description of the transport of the water and mineral ions from the endodermis to the xylem. Students are immediately challenged to use this knowledge to understand root pressure and the movement by mass flow down the pressure gradient. Moving forwards, time is taken to study the details of transpiration pull and the interaction between cohesion, tension and adhesion in capillary action is explained. Understanding is constantly checked through a range of tasks and prior knowledge checks are also written into the lesson to challenge the students to make links to previously covered topics such as the structure of the transport tissues. The final part of the lesson considers the journey of water through the leaf and ultimately out of the stomata in transpiration. A step by step guide using questions to discuss and answer as a class is used to support the students before the final task challenges them to summarise this movement out of the leaf.

A resourced lesson which looks at the chemical reaction that is aerobic respiration and ensures that students can apply their knowledge to application questions which challenge them to make links to related topics. The lesson includes an engaging lesson presentation (27 slides) and an associated worksheet containing questions. The lesson begins by challenging the students to recognise a definition for breathing and a definition for respiration. This is aimed at helping them to understand that these are different processes as this is a common misconception made by students. Moving forwards, key details about aerobic respiration are introduced to the students through a range of tasks which include competitions to maintain engagement. Time is taken to ensure that students become familiar with ATP and understand that this is the energy store which will be broken down to release energy for the activities that occur in a living organism. The remainder of the lesson challenges the students to take their new found knowledge of aerobic respiration and apply it to range of unfamiliar situations such as explaining why a root hair cell would have such a large number of mitochondria. There are regular progress checks throughout the lesson to allow the students to check on their understanding. As always, the lesson finishes with a slide containing advanced terminology so that students who have aspirations to take A-level Biology can extend and deepen their knowledge

A fully- resourced lesson which looks at the chemical reaction that is anaerobic respiration and ensures that students can understand why this form of respiration can only be used for short periods of time. The lesson includes an engaging lesson presentation (39 slides), a newspaper article and application questions. The lesson begins by challenging the students to recall information about aerobic respiration to recognise that the sole reactant of anaerobic respiration is glucose. A newspaper article about two atheletes from the 10000m race has been written to challenge the students to recognise why one of the athletes wouldnt be able to compete again in the near future whilst the other could. As a result, students will be introduced to lactic acid and will learn how this poisonous substance prevents muscle contraction and causes cramps. Time is taken to ensure that students are familiar with ATP and specifically that they recognise that a much lower yield is produced in this type of respiration. A perfect opportunity is taken to get the students to carry out a mathematical calculation to compare the yields. Oxygen debt is discussed and related back to the original newspaper article. Finally, anaerobic respiration in plants and yeast is considered in terms of fermentation and the word and symbol equation is written so that it can be compared to those from animals. There are regular progress checks throughout the lesson to allow the students to check on their understanding. The lesson has been written for GCSE students but could be used with higher ability KS3 students or A-level students who want a recap before covering the topic in greater detail on their course.

This fully-resourced lesson distinguishes between active and passive, natural and artificial immunity and explains how vaccinations can be used to control disease. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 11.2 (d) of the CIE A-level Biology specification and there is also a description and discussion on the concept of herd immunity. In topic 11.1, students were introduced to the primary and secondary immune responses so the start of this lesson uses an imaginary game of TOP TRUMPS to challenge them on the depth of their understanding. This will act to remind them that a larger concentration of antibodies is produced in a quicker time in the secondary response. The importance of antibodies and the production of memory cells for the development of immunity is emphasised and this will be continually referenced as the lesson progresses. The students will learn that this response of the body to a pathogen that has entered the body through natural processes is natural active immunity. Moving forwards, time is taken to look at vaccinations as an example of artificial active immunity. Another series of questions focusing on the MMR vaccine will challenge the students to explain how the deliberate exposure to antigenic material activates the immune response and leads to the retention of memory cells. A quick quiz competition is used to introduce the variety of forms that the antigenic material can take along with examples of diseases that are vaccinated against using these methods. The eradication of smallpox is used to describe the concept of herd immunity and the students are given time to consider the scientific questions and concerns that arise when the use of this pathway is a possible option for a government. The remainder of the lesson looks at the different forms of passive immunity and describes the drawbacks in terms of the need for a full response if a pathogen is re-encountered

This is a fully-resourced REVISION lesson which challenges the students on their knowledge of the content in TOPIC B5 (Genetics) of the Edexcel GCSE Combined Science specification. The lesson uses an engaging PowerPoint (63 slides) and accompanying worksheets to motivate students whilst they assess their understanding of this topic. A range of exam questions, quick tasks and quiz competitions are used to test the following sub-topics: Recognising and using genetic terminology in context Constructing genetic diagrams to calculate offspring percentages for diseases caused by dominant and recessive alleles The sex chromosomes and sex determination Meiosis and the formation of haploid daughter cells The structure of DNA Extracting DNA from a fruit Genetic and environmental variation Mutations and their effect on the phenotype The mathematical element of the course is also tested throughout the lesson and students are given helpful hints on exam techniques and how to structure answers. This resource is suitable for use at the end of topic B3 or in the lead up to mocks or the actual GCSE exams.

This is a fully-resourced REVISION lesson which challenges the students on their knowledge of the content in TOPIC B2 (Cells and control) of the Edexcel GCSE Combined Science specification. The lesson uses an engaging PowerPoint (70 slides) and accompanying worksheets to motivate students whilst they assess their understanding of this topic. A range of exam questions, quick tasks and quiz competitions are used to test the following sub-topics: The structure of the CNS Reflex reactions and the neurones involved Synapses Mitosis and the cell cycle The use of percentile charts to monitor growth Cell differentiation and specialisation Stem cells and their potential for use in medicine There is a big emphasis on the mathematical elements of the course such as percentage change and standard form and students are given helpful hints on exam techniques and how to structure answers. This resource is suitable for use at the end of topic B2 or in the lead up to mocks or the actual GCSE exams.

This lesson describes the active loading of assimilates like sucrose at the source and the translocation along the phloem to the sink. Both the detailed PowerPoint and accompanying resources have been designed to cover point 3.1.3 (f) of the OCR A-level Biology A specification. The lesson begins by challenging the students to recognise the key term translocation when it is partially revealed and then the rest of the lesson focuses on getting them to understand how this process involves the mass flow of assimilates down the hydrostatic pressure gradient from the source to the sink. It has been written to tie in with 3.1.3 (b) where the structure of the phloem tissue was initially introduced and the students are continually challenged on this prior knowledge. A step-by-step guide is used to describe how sucrose is loaded into the phloem at the source by the companion cells. Time is taken to discuss key details such as the proton pumping to create the proton gradient and the subsequent movement back into the cells by facilitated diffusion using co-transporter proteins. Students will learn that the hydrostatic pressure at the source is high, due to the presence of the water and sucrose as cell sap, and that this difference when compared to the lower pressure at the sink leads to the movement along the phloem. A number of quick quiz rounds are included in the lesson to maintain engagement and to introduce key terms and the lesson concludes with a game of SOURCE or SINK as students have to identify whether a particular plant structure is one or the other (or both)

An engaging lesson which focuses on the key terms which are involved in the ecology topic of food chains and food webs. Although this lesson is primarily designed for GCSE students, the content is suitable with KS3 students who are looking at the ecological relationships between organisms. The lesson begins by ensuring that students are confident in the construction of a food chain and that any common mistakes such as the arrows pointing in the wrong direction are eliminated. As with the other ecology lessons that I have designed, “ecology bingo” runs throughout the lesson to engage the students but also to challenge their recognition of key terms from definitions. Key terms such as producers and consumers are revisited in this lesson. The students will recall the names for the three types of consumers, based on their diets, and will make the link between the positions of producers, herbivores and carnivores in food chains. The remainder of the lesson focuses on the construction of a food web and describing changes in the numbers of organisms when there is a change to one of the other populations. Progress checks have been written into the lesson at regular intervals so students can constantly assess their understanding.

This fully-resourced lesson explores the inheritance of genetic characteristics that involve multiple alleles and codominant alleles. The engaging and detailed PowerPoint and differentiated worksheets have been designed to cover the part of point 16.2 (b) of the CIE International A-level Biology specification which states that students should be able to use genetic diagrams to solve problems which involve codominance and multiple alleles. The main part of the lesson uses the inheritance of the ABO blood groups to demonstrate how the three alleles that are found at the locus on chromosome 9 and the codominance of the A and B alleles affects the phenotypes. Students are guided through the construction of the different genotypes and how to interpret the resulting phenotype. They are challenged to use a partially completed pedigree tree to determine the blood group for some of the family members and to explain how they came to their answer. To further challenge their ability to apply their knowledge, a series of questions about multiple alleles and codominance in animals that are not humans are used. All of the questions are followed by clear, visual mark schemes to allow the students to assess their progress and address any misconceptions

This lesson describes and explains how increasing the concentration of inhibitors affects the rate of an enzyme-catalysed reaction. The PowerPoint and accompanying resource are the last in a series of 4 lessons which cover the content detailed in point 3.2 (a) of the CIE A-level Biology specification but this lesson also covers point 3.2 [c] as competitive and non-competitive inhibitors are introduced and their differing effects on enzyme activity described and explained. The lesson begins with a made up round of the quiz show POINTLESS called “Biology opposites” and this allows students to recognise that inhibition is the opposite of stimulation. This introduces inhibitors as substances that reduce the rate of a reaction and students are challenged to use their general knowledge of enzymes to identify that inhibitors prevent the formation of the enzyme-substrate complex. Moving forwards, a quick quiz competition generates the abbreviation EIC (representing enzyme-inhibitor complex) and this introduces competitive inhibitors as substances that occupy the active site. The students are asked to apply their knowledge to a new situation to work out that these inhibitors must have a similar shape to the enzyme’s substrate molecule. A series of exam-style questions are used throughout the lesson and at this point, the students are challenged to work out that an increase in the substrate concentration would reduce the effect of a fixed concentration of a reversible competitive inhibitor. The rest of the lesson focuses on non-competitive inhibitors and time is taken to ensure that key details such as the disruption of the tertiary structure is understood and biological examples are used to increase the relevance. Again, students will learn that increasing the concentration of the inhibitor results in a greater inhibition and a reduced rate of reaction but that increasing the substrate concentration cannot reduce the effect as was observed with competitive inhibitors.

This detailed lesson describes how urea is produced from excess amino acids and then removed from the bloodstream by ultrafiltration. The PowerPoint and accompanying resources have been designed to cover point 7.19 of the Edexcel International A-level Biology specification. The first part of the lesson describes how deamination and the ornithine cycle forms urea. Although the students are not required to know the details of the cycle, it is important that they are aware of how the product of deamination, ammonia, is converted into urea (and why). Moving forwards, the rest of the lesson has been written to allow the students to discover ultrafiltration as a particular function of the nehron and to be able to explain how the mechanisms found in the glomerulus and the Bowman’s capsule control the movement of small molecules out of the blood plasma. Key terminology is used throughout and students will learn how the combination of the capillary endothelium and the podocytes creates filtration slits that allow glucose, water, urea and ions through into the Bowman’s capsule but ensure that blood cells and plasma proteins remain in the bloodstream. A number of quiz competitions are used to introduce key terms and values in a fun and memorable way whilst understanding and prior knowledge checks allow the students to assess their understanding of the current topic and to challenge themselves to make links to earlier topics. The final task of the lesson challenges the students to apply their knowledge by recognising substances found in a urine sample that shouldn’t be present and to explain why this would cause a problem

This fully-resourced lesson introduces bacteriostatic and bactericidal antibiotics and describes their differences, focusing on their modes of action. The engaging PowerPoint and accompanying resources have been designed to cover point 6.14 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification but also makes continual links to earlier lessons in topic 6 as well as related topics from the previous year such as protein synthesis from topic 2 The lesson begins by challenging the students to use their knowledge of the previous topic 6 lessons to identify the suffixes cidal and static. Students will learn that when the prefix is added, these form the full names of two types of antibiotics. Their understanding of terminology is tested further as they have to recognise that Polymyxin B is an example of a bactericidal antibiotic as its actions would result in the death of the bacterial cell. Tetracycline is used as the example of a bacteriostatic antibiotic and students will discover that its prevention of the binding of tRNA that inhibits protein synthesis and this reduction and stopping of growth and reproduction is synonymous with these drugs. Students are challenged on their knowledge of translation and will also be given time for a class discussion to understand that these antibiotics encourage the body’s immune system to overcome the pathogen in natural, active immunity. The final part of the lesson uses a quick quiz competition and a series of exam-style questions to ensure that students can recognise the different antibiotics from descriptions.

This lesson guides students through the use of a chi-squared test to determine the significance of the difference between observed and expected results. It is fully-resourced with a detailed PowerPoint and differentiated worksheets that have been designed to cover point (d) in topic 3 of A2 unit 4 of the WJEC A-level Biology specification The lesson includes a step-by-step guide to demonstrates how to carry out the test in small chunks. At each step, time is taken to explain any parts which could cause confusion and helpful hints are provided to increase the likelihood of success in exam questions on this topic. Students will understand how to use the phenotypic ratio to calculate the expected numbers and then how to find the critical value in order to compare it against the chi-squared value. A worked example is used to show the working which will be required to access the marks and then the main task challenges the students to apply their knowledge to a series of questions of increasing difficulty. This lesson has been specifically designed to tie in with the previous lessons in this topic as there are regular references to dihybrid inheritance as well as to topics in the AS units like meiosis

This fully-resourced lesson explains why the speed of transmission along myelinated axons is greater than along non-myelinated axons. The PowerPoint and accompanying resources have been designed to cover point 9.5 (iii) of the Edexcel A-level Biology B specification which states that students should understand the role of saltatory conduction in the transmission of action potentials. A wide range of activities have been written into this resource to maintain the motivation of the students whilst ensuring that the detail is covered in real depth. Interspersed with the activities are understanding checks and prior knowledge checks to allow the students to not only assess their understanding of the current topic but also challenge themselves to make links to earlier topics such as the movement of ions across membranes and biological molecules. Time at the end of the lesson is also given to future knowledge such as the involvement of autonomic motor neurones in the stimulation of involuntary muscles. Over the course of the lesson, students will learn and discover the myelin sheath wrapped around the axons of sensory and motor neurones allows these neurones to conduct impulses quickly between receptors and the CNS and between the CNS and effectors. There is a focus on this myelin sheath and specifically how the insulation is not complete all the way along which leaves gaps known as the nodes of Ranvier which allow the entry and exit of ions. Saltatory conduction is poorly understood (and explained) by a lot of students so time is taken to look at the way that the action potential jumps between the nodes and this is explained further by reference to local currents. The rest of the lesson focuses on the other two factors which are axon diameter and temperature and students are challenged to discover these two by focusing on the vampire squid.

This detailed lesson describes the gross and microscopic structure of the mammalian kidney. The engaging PowerPoint and accompanying resource have been designed to cover point 7.18 of the Edexcel International A-level Biology specification. The lesson was designed to tie in with the upcoming kidney lessons (7.19 - 7.21) on ultrafiltration, selective reabsorption and the control of mammalian plasma concentration and a common theme runs throughout to allow students to build their knowledge gradually and develop a deep understanding of this organ. Students will come to recognise the renal cortex and renal medulla as the two regions of the kidney and learn the parts of the nephron which are found in each of these regions. Time is taken to look at the vascular supply of this organ and specifically to explain how the renal artery divides into the afferent arterioles which carry blood towards the glomerulus and the efferent arterioles which carry the blood away. The main task of the lesson challenges the students to relate structure to function. Having been introduced to the names of each of the parts of the nephron, they have to use the details of the structures found at these parts to match the function. For example, they have to make the connection between the microvilli in the PCT as a sign that this part is involved in selective reabsorption.

This lesson describes the meaning of the term stem cell and the differences between totipotent, pluripotent and multipotent stem cells. The PowerPoint and accompanying worksheets have been designed to cover points 7.3 (i) and (ii) of the Edexcel A-level Biology B specification meaning that this lesson also contains discussion periods about the potential opportunities to use stem cells from embryos in medicine. The lesson begins with a knowledge recall of the structure of eukaryotic cells and the students have to use the first letters of each of the four answers to reveal the key term, stem cell. Time is then taken to consider the meaning of cellular differentiation, and this leads into the key idea that not all stem cells are equal when it comes to the number of cell types that they have the potential to differentiate into. A quick quiz round introduces the five degrees of potency, and then the students are challenged to use their understanding of terminology to place totipotency, pluripotency, multipotency, oligopotency and unipotency in the correct places on the potency continuum. Although the latter two do not have to be specifically known based on the content of specification point 7.3 (i), an understanding of their meaning was deemed helpful when planning the lesson as it should assist with the retention of knowledge about totipotency, pluripotency and multipotency. These three highest degrees of potency are the main focus of the lesson, and key details are emphasised such as the ability of totipotent cells to differentiate into any extra-embroyonic cell, which the pluripotent cells are unable to do. The morula, and inner cell mass and trophoblast of the blastocyst are used to demonstrate these differences in potency. The final part of the lesson discusses the decisions that the scientific community have to make about the use of pluripotent embryonic stem cells, adult stem cells and also multipotent foetal stem cells As there is a heavy mathematical content in the current A-level Biology exams, a Maths in a Biology context question is included in the lesson (when introducing the morula) to ensure that students continue to be prepared for the numerous calculations that they will have to tackle in the terminal exams. This resource has been differentiated two ways to allow students of differing abilities to access the work