An engaging lesson presentation (81 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within Topic 7 (Animal coordination and homeostasis) of the EDEXCEL GCSE Biology specification The topics that are tested within the lesson include: The endocrine system Thyroxine The menstrual cycle Hormonal and barrier methods of contraception Homeostasis Thermoregulation Osmoregulation Control of blood glucose concentration DIabetes Students will be engaged through the numerous activities including quiz rounds like “Have they got the right BALANCE?" and the “B7 ABBREVIATIONS” whilst crucially being able to recognise those areas which need further attention

An engaging lesson presentation (75 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B7(Ecology) of the AQA GCSE Biology specification (specification unit B4.7). The topics that are tested within the lesson include: Communities Abiotic factors Biotic factors Levels of organisation Recycling materials Decomposition Deforestation Global warming Trophic levels Pyramids of biomass Transfer of biomass Students will be engaged through the numerous activities including quiz rounds like “Number CRAZY" whilst crucially being able to recognise those areas which need further attention

This lesson describes how the primary structure determines the secondary structure, 3D structure and properties of a protein. The detailed and engaging PowerPoint and accompanying resources have been designed to cover points 2.6 (ii) & (iii) of the Edexcel International A-level Biology specification but also makes specific reference to genes and protein synthesis and therefore introduces students to processes covered later in topic 2. The start of the lesson focuses on the formation of a peptide bond during a condensation reaction so that students can understand how a dipeptide is formed and therefore how a polypeptide forms when multiple reactions occur. The main part of the lesson describes the different levels of protein structure. A step by step guide is used to demonstrate how the sequences of bases in a gene acts as a template to form a sequence of codons on a mRNA strand and how this is translated into a particular sequence of amino acids known as the primary structure. The students are then challenged to apply their understanding of this process by using three more gene sequences to work out three primary structures and recognise how different genes lead to different sequences. Moving forwards, students will learn how the order of amino acids in the primary structure determines the shape of the protein molecule, through its secondary, tertiary and quaternary structure and time is taken to consider the details of each of these. There is a particular focus on the different bonds that hold the 3D shape firmly in place and a quick quiz round then introduces the importance of this shape as exemplified by enzymes, antibodies and hormones. The lesson concludes with one final task where the students have to identify three errors in a passage about the hydrolysis of a dipeptide or polypeptide.

This detailed and fully-resourced lesson describes the relationship between the structure and function of the polysaccharides: glycogen, starch and cellulose. The engaging PowerPoint and accompanying resources have been designed to cover point 1.1 (iv) as it is detailed in the Edexcel A-level Biology B specification and clear links are also made to the previous lessons in this topic where the monosaccharides and disaccharides were introduced. By the end of this lesson, students should understand how key structural features like the 1 - 4 and 1 - 6 glycosidic bonds and the hydrogen bonds dictate whether the polysaccharide chain is branched or unbranched and also whether it spirals or not. A range of activities are used to motivate and engage the students as they discover that glycogen is stored in liver and muscle cells, which it is able to do because of its compact structure. They are encouraged to discuss why the branched structure of this polysaccharide means that it can act as an immediate source of energy and they will recognise that hydrolysis reactions at the multiple ends of this chain will release glucose. Following on from the description of the structure of glycogen, students are challenged to design an exam question in the form of a comparison table so that it can be completed as the lesson progresses once they learn more about starch and cellulose. This includes a split in the starch section of the table so that the differing structures and properties of amylose and amylopectin can be considered. In the final part of the lesson, time is taken to focus on the formation of cellulose microfibrils and macrofibrils to explain how plant cells have the additional strength needed to support the whole plant. Due to the detail included in this lesson, it is estimated that it will take in excess of 2 hours of allocated teaching time to complete

This detailed lesson describes the role of the strand of mRNA, the tRNA molecules, the amino acids and the ribosome during the second stage of protein synthesis - translation. Both the PowerPoint and accompanying resources have been designed to cover the second part of point 6.2 (d) of the CIE International A-level Biology specification and ties in with the first part of this specification point which covered transcription. Translation is a topic which is often poorly understood and so this lesson has been written to enable the students to understand how to answer the different types of questions by knowing and including the key details of the structures involved. The lesson begins by challenging the students to consider why it is so important that the amino acids are assembled in the correct order during the formation of the chain. Moving forwards, a quick quiz round called “LOST IN TRANSLATION” is used to check on their prior knowledge of the mRNA strand, the tRNA molecules, the genetic code and the ribosomes. The next task involves a very detailed description of translation that has been divided into 14 statements which the students have to put into the correct order. By giving them a passage that consists of this considerable detail, they can pick out the important parts to use in the next task where they have to answer shorter questions worth between 3 and 4 marks. These types of questions are common in the assessments and by building up through the lesson, their confidence to answer this type should increase. The final two tasks of the lesson involve another quiz called “The protein synthesis game”, where the teams compete to transcribe and translate in the quickest time before using all the information from the lessons on protein synthesis to answer some questions which involve the genetic code and the mRNA codon table.

This fully-resourced lesson describes how evolution can come through natural selection and acts on variation to bring about adaptations. The PowerPoint and accompanying resources have been designed to cover specification points 3.2 (i) & (ii) of the Edexcel A-level Biology B specification and considers a range of different behavioural, anatomical and physiological adaptations. President Trump’s error ridden speech about antibiotics is used at the beginning of the lesson to remind students that this is a treatment for bacterial infections and not viruses as he stated. 2 quick quiz competitions are used to introduce MRSA and then to get the students to recognise that they can use this abbreviation to remind them to use mutation, reproduce, selection (and survive) and allele in their descriptions of evolution through natural selection. The main task of the lesson challenges the students to form a description that explains how this strain of bacteria developed resistance to methicillin to enable them to see the principles of natural selection. This can then be used when describing how the anatomy of the modern-day giraffe has evolved over time. The concept of convergent evolution is introduced and links are made to the need for modern classification techniques. Moving forwards, students will understand how natural selection leads to adaptations and a quick quiz competition introduces the different types of adaptation and a series of tasks are used to ensure that the students can distinguish between anatomical, behavioural and physiological adaptations. The Marram grass is used to test their understanding further, before a step by step guide describes how the lignified cells prevent a loss of turgidity. Moving forwards, the students are challenged to explain how the other adaptations of this grass help it to survive in its environment. The final part of the lesson focuses on the adaptations of the anteater and links are made to the topic of classification hierarchy which was covered at the start of topic 3… Due to the extensiveness of this lesson and the detail contained within the resources, it is estimated that it will take in excess of 2 hours of allocated A-level teaching time to deliver this lesson.

This fully-resourced lesson describes the light independent reaction of photosynthesis and explains how reduced NADP is used to form a simple sugar. The detailed PowerPoint and accompanying resources have been designed to cover the second part of point 5.1 of the AQA A-level Biology specification and lengthy planning has ensured that links are continually made to the previous lesson on the light-dependent reaction so that students can understand how the products of that stage are essential for the Calvin cycle The lesson begins with an existing knowledge check where the students are challenged to recall the names of structures, substances and reactions from the light-dependent stage in order to reveal the abbreviations of the main 3 substances in the light-independent stage. This immediately introduces RuBP, GP and TP and students are then shown how these substances fit into the cycle. The main section of the lesson focuses on the three phases of the Calvin cycle and time is taken to explore the key details of each phase and includes: The role of RuBisCO in carbon fixation The role of the products of the light-dependent stage, ATP and reduced NADP, in the reduction of GP to TP The use of the majority of the TP in the regeneration of RuBP A step-by-step guide, with selected questions for the class to consider together, is used to show how 6 turns of the cycle are needed to form the TP that will then be used to synthesise 1 molecule of glucose. A series of exam-style questions are included at appropriate points of the lesson and this will introduce limiting factors as well as testing their ability to answer questions about this stage when presented with an unfamiliar scientific investigation. The mark schemes are included in the PowerPoint so students can assess their understanding and any misconceptions are immediately addressed. This lesson has been specifically written to tie in with the previous lessons on the structure of a chloroplast and the light-dependent stage as well as upcoming lesson on limiting factors

This fully-resourced lesson focuses on the events of meiosis which specifically contribute to genetic variation. The detailed PowerPoint and accompanying resources have been designed to cover the 4th and final part of point 4.3 of the AQA A-level Biology specification which states that students should be able to describe how meiosis produces daughter cells that are genetically different from each other. In order to understand how the events of meiosis like crossing over and random assortment and independent segregation can lead to variation, students need to be clear in their understanding that DNA replication in interphase results in homologous chromosomes as pairs of sister chromatids. Therefore the beginning of the lesson focuses on the chromosomes in the parent cell and this first part of the cycle and students will be introduced to non-sister chromatids and the fact that they may contain different alleles which is important for the exchange that occurs during crossing over. Time is taken to go through this event in prophase I in a step by step guide so that the students can recognise that the result can be new combinations of alleles that were not present in the parent cell. Moving forwards, the lesson explores how the independent segregation of chromosomes and chromatids during anaphase I and II results in genetically different gametes. The final part of the lesson looks at the use of a mathematical expression to calculate the possible combinations of alleles in gametes as well as in a zygote following the random fertilisation of haploid gametes. Understanding and prior knowledge checks are interspersed throughout the lesson as well as a series of exam questions which challenge the students to apply their knowledge to potentially unfamiliar situations. Due to the detail of this lesson, it is estimated that this will take about 2 hours of A-level teaching time to deliver

This fully-resourced lesson explores how projects to sequence the genomes of both simple and complex organisms can be used. Both the detailed PowerPoint and accompanying resources have been designed to cover the content of point 8.3 of the AQA A-level Biology specification. The start of the lesson describes each step of Sanger’s chain termination method and demonstrates how this method has paved the way for other projects. The use of the modified nucleotides are explained and links are made to the topic 4 and 2 where protein synthesis and DNA replication were first introduced. Students will learn how the radioactively-labelled nucleotide at the end of each fragment allows the next base to be determined. Key processes like gel electrophoresis are introduced and details provided to support the students when this is encountered in greater detail in 8.4.3. Moving forwards, the applications of sequencing in simple organisms like viruses and bacteria are explored and the students are challenged on their prior knowledge of bacterial pathogenesis and current understanding of sequencing through a series of exam-style questions. The final part of the lesson looks at the difficulties of translating genome knowledge into proteome knowledge and considers the development of automated methods. Due to the detail and extensiveness of this lesson, it is estimated that it will take in excess of 2 hours of allocated A-level teaching time to cover all of the points which have been written into the various tasks

This fully-resourced lesson describes how the structure of the xylem tissue allows water to be transported in the stem and leaves. Written for AQA A-level Biology, the engaging and detailed PowerPoint and the accompanying worksheets cover the 1st part of specification point 3.4.2 (mass transport in plants) and includes a detailed description of the cohesion-tension theory. The first part of the lesson focuses on the relationship between the structure and function of the xylem tissue. A number of quiz competitions have been included in the lesson to maintain engagement and to introduce key terms. The 1st round does just that and results in the introduction of lignin which leads into the explanation of how the impregnation of this substance in the cell walls result in the death and subsequent decay of the cell structures. Students are encouraged to discuss how the formation of this hollow tube enables the transport of water to be effective. Moving forwards, other structures such as the bordered pits are introduced and an understanding of their function is tested later in the lesson. The remainder of the lesson focuses on the transport of water in the stem and leaves by root pressure and the transpiration pull, which includes cohesion, tension and adhesion. The lesson has been designed to make links to information covered earlier in the lesson as well to topics from earlier in the specification such as cell structures and biological molecules Due to the extensiveness of this lesson, it is estimated that it will take in excess of 2/3 A-level teaching hours to cover the detail included in this lesson.

A fully-resourced lesson that looks at the different sampling methods that can be used to estimate the populations of animals and plants in a habitat and to analyse how their distribution is affected, The lesson includes a detailed and engaging lesson presentation (56 slides) and differentiated worksheets so that students of different abilities are challenged and can access the work. The lesson begins by looking at the use of a quadrat to estimate the population of plants in a habitat. There is a focus on the mathematical calculations associated with the method and students are given hints and worked examples so that any common misconceptions are addressed. Moving forwards, students are introduced to the capture-mark-recapture technique to sample animals. The rest of the lesson looks at alternative pieces of apparatus, such as the sweep net, and discusses situations when these would be used. This lesson has been written for GCSE students (14 - 16 year olds in the UK) but is appropriate for both younger students who are learning about ecology and also for A-level students who need a recap on this topic.

This is a highly detailed and engaging lesson that covers the detail of the 2nd part of specification point 6.2.1 of the AQA A-level Biology specification which states that students should be able to describe the establishment of resting potential, the changes in membrane potential that lead to depolarisation and the importance of the refractory period. This topic is commonly assessed in the terminal exams so a lot of time has been taken to design this resource to include a wide range of activities that motivate the students whilst ensuring that the content is covered in the depth of detail that will allow them to have a real understanding. Interspersed within the activities are understanding checks and prior knowledge checks to enable the students to not only assess their progress against the current topic but also to challenge themselves on the links to earlier topics such as methods of movements across cell membranes and saltatory conduction. There are also a number of quiz competitions which are used to introduce key terms and values in a fun and memorable way and discussion points to encourage the students to consider why a particular process or mechanism occurs. Over the course of the lesson, the students will learn and discover how the movement of ions across the membrane causes the membrane potential to change. They will see how the resting potential is maintained through the use of the sodium/potassium pump and potassium ion leakage. There is a real focus on depolarisation to allow students to understand how generator potentials can combine and if the resulting depolarisation then exceeds the threshold potential, a full depolarisation will occur. At this point in the lesson students will discover how the all or nothing response explains that action potentials have the same magnitude and that instead a stronger stimulus is linked to an increase in the frequency of the transmission. The rest of the lesson challenges the students to apply their knowledge to explain how repolarisation and hyperpolarisation result and to suggest advantages of the refractory period for nerve cells. This lesson has been designed for students studying the AQA A-level Biology course and ties in nicely with other uploaded lessons on mammalian sensory receptors and the structures and functions of the neurones.

This fully-resourced lesson is highly detailed and in combination with the uploaded lesson on the causes of diabetes type I and II, it covers all of specification point 6.4.2 of the AQA A-level Biology specification which states that students should be able to describe the homeostatic control of blood glucose concentration using negative feedback mechanisms that release insulin or glucagon. A wide range of activities will maintain motivation and engagement whilst the content is covered in detail to enable the students to explain how the receptors in the pancreas detect the concentration change and how the hormones attaching to receptor sites on the liver triggers a series of events in this effector organ. This is a topic which has a huge amount of difficult terminology so time is taken to look at all of the key words, especially those which begin with the letter G so students are able to use them accurately in the correct context. The action of adrenaline is also considered and linked to the breakdown of glycogen to glucose during glycogenolysis. This lesson has been written for students studying on the AQA A-level Biology course and ties in with the already mentioned lesson on diabetes but also with the other uploaded lessons on topic 6 such as nerve impulses and kidney function

This detailed lesson describes the role of the mRNA, tRNA, amino acids and the ribosome during the second stage of protein synthesis - translation. Both the PowerPoint and accompanying resources have been designed to cover the third part of point 4.2 of the AQA A-level Biology specification and ties in with the previous lessons in this topic on RNA and transcription. Translation is a topic which is often poorly understood and so this lesson has been written to enable the students to understand how to answer the different types of questions by knowing and including the key details of the structures involved. The lesson begins by challenging the students to consider why it is so important that the amino acids are assembled in the correct order during the formation of the chain. Moving forwards, a quick quiz round called “LOST IN TRANSLATION” is used to check on their prior knowledge of the mRNA strand, the tRNA molecules, the genetic code and the ribosomes. The next task involves a very detailed description of translation that has been divided into 14 statements which the students have to put into the correct order. By giving them a passage that consists of this considerable detail, they can pick out the important parts to use in the next task where they have to answer shorter questions worth between 3 and 4 marks. These types of questions are common in the assessments and by building up through the lesson, their confidence to answer this type should increase. The final two tasks of the lesson involve another quiz, where the teams compete to transcribe and translate in the quickest time before using all that they have learnt to answer some questions which involve the genetic code and the mRNA codon table.

A fully-resourced lesson, which explores how changes to the sequence of bases on DNA may or may not alter protein structure. The engaging PowerPoint and accompanying resources have been designed to cover point 8.1 of the AQA A-level Biology specification and it builds on the knowledge gained during topic 4 when gene mutations were first introduced. A quiz runs throughout the lesson where students compete to recognise key terms from their definitions and the lesson begins with an edition of this round as they are challenged to recognise the definition for primary structure. Other terms that arise during the lesson relate to the different gene mutations, the genetic code and mutagenic agents. The focus of the lesson is to support students in their explanations of how a particular mutation can result in a change in the primary structure as well as being able to explain why a substitution mutation may not. In this way, their understanding of the degenerate and non-overlapping nature of the genetic code will be tested and any misconceptions can be addressed. The main section of the lesson covers substitution, deletion and addition mutations before translocation, inversion and duplication mutations are introduced. Links are made to the latter parts of topic 8 so students can understand how the change in the sequence of bases may disrupt gene expression. The final part of the lesson looks at a range of mutagenic agents that can increase the rate of mutation.

An engaging lesson presentation (43 slides) that uses exam questions, quick tasks and competitions to enable students to assess their understanding of the topics within module 6.1.3 of the OCR A-Level Biology A specification. All of the exam questions have displayed mark schemes and explanations so that students can recognise any errors or misconceptions. Competition rounds included in this lesson are "From numbers 2 letters" and "Is this SEQUENCED correctly".

A fully resourced revision lesson which uses a range of exam questions (with explained answers), quick tasks and quiz competitions to enable the students to assess their understanding of the topics found within module 3 (Exchange and transport) of the OCR A-level Biology specification. The topics tested within this lesson include: Exchange surfaces Mammalian gaseous exchange system Tissues in the gaseous exchange system Transport in animals Blood vessels Exchange at the capillaries ECG Transport of oxygen Transport in plants Transport tissues Movement of water through plants Transpiration Translocation Student will enjoy the range of tasks and quiz rounds whilst crucially being able to recognise any areas which require further attention

This fully-resourced lesson covers the content of the first part of specification point 6.2.2 of the AQA A-level Biology specification that states that students should be able to describe the detailed structure of a cholinergic synapse and a neuromuscular junction and be able to compare the transmission across both of these structures. The majority of the lesson uses the cholinergic synapse as the example but other neurotransmitters and drugs are considered so students are prepared to describe the differing effects on the synapse. The lesson begins by using a version of the WALL (as shown in the cover image) which asks the students to group 12 words into three groups of 4. Not only will this challenge their prior knowledge from topics earlier in this module but it will also lead to the discovery of four of the structures that are found in a synapse. Moving forwards, students are introduced to aectylcholine as the neurotransmitter involved at cholinergic synapses and they will start to add labels to the structures found in the pre-synaptic bulb. Time is taken to focus on certain structures such as the voltage gated channels as these types of channel were met previously when looking at the depolarisation of a neurone. There is plenty of challenge and discovery as students are pushed to explain why organelles like mitochondria would be found in large numbers in the bulb. With this process being a cascade of events, a bullet point format is used to ensure that the key content is taken in by the students and again key points like exocytosis and the action of acetylcholinesterase are discussed further. The next part of the lesson challenges the application aspect of the specification as students are introduced to unfamiliar situations in terms of synapses with new drugs like MDMA and are asked to work out and explain how these affect the nervous transmission. The final part of the lesson focuses on the NMJ and challenges the students to use the knowledge gained from earlier in the lesson to develop their understanding of these junctions. Time is taken to look at the structure of the sarcolemma to enable students to understand how the binding of the acetylcholine leads to the wave of depolarisation passing to the transverse tubules. Understanding checks and prior knowledge checks are included throughout the lesson so that students can not only assess their progress against the current topic but also see whether they can make links to earlier topics. This lesson has been designed for students studying the AQA A-level Biology course but could be used with very able GCSE students who are keen to develop their understanding of synapses over and above the small detail that is provided at that level. This lesson also ties in nicely with the other uploaded lessons from topic 6

This lesson describes and explains the changes in membrane potential of neurones, focusing on resting potential, depolarisation and repolarisation. The detailed PowerPoint and accompanying resources have been planned to cover the content of point (6) of topic 15.1 of the CIE A-level Biology specification. Hyperpolarisation and the refractory period are not covered in this lesson, but during a lesson titled “The refractory period” which covers specification point (8). This topic is commonly assessed in the terminal exams so a lot of time has been taken to design this resource to include a wide range of activities that motivate the students whilst ensuring that the content is covered in the depth of detail that will allow them to have a deep understanding. Interspersed within the activities are understanding checks and prior knowledge checks to enable the students to not only assess their progress against the current topic but also to challenge themselves on the links to earlier topics such as methods of movements across cell membranes. There are also several quiz competitions which introduce key terms and values in a fun and memorable way and discussion points to encourage the students to consider why a particular process or mechanism occurs. Over the course of the lesson, the students will learn and discover how the movement of ions across the membrane causes the membrane potential to change. They will see how the resting potential is maintained through the use of the sodium/potassium pump and potassium ion leakage. There is a real focus on depolarisation to allow students to understand how generator potentials can combine and if the resulting depolarisation then exceeds the threshold potential, a full depolarisation will occur. At this point in the lesson students will discover how the all or nothing response explains that action potentials have the same magnitude and that instead a stronger stimulus is linked to an increase in the frequency of the transmission. The rest of the lesson challenges the students to apply their knowledge to understand repolarisation.