This fully-resourced lesson looks at the effects of nervous mechanisms on the heart rate. The engaging and detailed PowerPoint and accompanying resources have been designed to cover the part of point 5.1.5 (k) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the control of the heart rate by the cardiovascular centre in the medulla oblongata This lesson begins with a prior knowledge check where students have to identify and correct any errors in a passage about the conduction system of the heart. This allows the SAN to be recalled as this structure play an important role as the effector in this control system. Moving forwards, the three key parts of a control system are recalled as the next part of the lesson will specifically look at the range of sensory receptors, the coordination centre and the effector. Students are introduced to chemoreceptors and baroreceptors and time is taken to ensure that the understanding of the stimuli detected by these receptors is complete and that they recognise the result is the conduction of an impulse along a neurone to the brain. A quick quiz is used to introduce the medulla oblongata as the location of the cardiovascular centre. The communication between this centre and the SAN through the autonomic nervous system can be poorly understood so detailed explanations are provided and the sympathetic and parasympathetic divisions compared. The final task challenges the students to demonstrate and apply their understanding by writing a detailed description of the control and this task has been differentiated three ways to allow differing abilities to access the work

This is an engaging and informative lesson that looks at the meaning of excretion in detail and explores the functions of the organs involved with the excretion of carbon dioxide and urea. This lesson has been designed for students studying A-level Biology. The lesson begins by introducing the definition of excretion to the students so that they are able to recognise that the substances being removed have to have come from a metabolic process in order to be excreted. This important difference to egestion (elimination) is a key detail which they need to understand at this level. Moving forwards, a quick competition is used to meet some of the organs that are involved in excretion. The remainder of the lesson focuses on the excretion of carbon dioxide. Links are made to the transport of carbon dioxide as hydrogen carbonate ions and how the affinity of haemoglobin for oxygen is affected when the carbon dioxide concentration is high. Students will meet the idea of deamination and the ornithine cycle and the key details of these two processes are covered. Progress checks have been written into this lesson at regular intervals, which challenge the students on knowledge from this lesson and prior knowledge, to enable them to constantly assess their understanding.

This detailed lesson describes the role of the mRNA, tRNA, rRNA and amino acids during the second stage of protein synthesis - translation. Both the PowerPoint and accompanying resources have been designed to cover the second part of point 2.1.3 (g) of the OCR A-level Biology A specification and continually links back to the previous lessons in this module on the structure of DNA and RNA and the genetic code Translation is a topic which is often poorly understood and so this lesson has been written to enable the students to understand how to answer the different types of questions by knowing and including the key details of the structures involved. The lesson begins by challenging the students to consider why it is so important that the amino acids are assembled in the correct order during the formation of the chain. Moving forwards, a quick quiz round called “LOST IN TRANSLATION” is used to check on their prior knowledge of the mRNA strand, the tRNA molecules, the genetic code and the ribosomes. The next task involves a very detailed description of translation that has been divided into 14 statements which the students have to put into the correct order. By giving them a passage that consists of this considerable detail, they can pick out the important parts to use in the next task where they have to answer shorter questions worth between 3 and 4 marks. These types of questions are common in the assessments and by building up through the lesson, their confidence to answer this type should increase. The final two tasks of the lesson involve another quiz, where the teams compete to transcribe and translate in the quickest time before using all that they have absorbed to answer some questions which involve the genetic code and the mRNA codon table

This lesson focuses on the structure of RNA and specifically the similarities and differences between this nucleic acid and DNA so that students are prepared for the upcoming lessons on transcription and translation. The engaging and detailed PowerPoint and accompanying resource have been designed to cover part 1 of point 2.1.3 (g) of the OCR A-level Biology A specification which states that students should be able to describe the structure of molecules of messenger RNA, transfer RNA and ribosomal RNA. Students were introduced to nucleotides and the detailed structure of DNA in previous lessons, so this lesson is written to tie in with those and continuously challenge prior knowledge as well as understanding of the current topic. The lesson begins by reminding students that RNA is a member of the family of nucleic acids and therefore has a number of structural features that are commonly shared with DNA. A quiz round called “A FAMILY AFFAIR” is used to challenge their knowledge of DNA to recognise those features that are also found on RNA such as the chain of linked nucleotides, pentose sugars, nitrogenous bases and phosphodiester bonds. The next task pushes them to consider features that have not been mentioned and therefore are differences as they answer a structured exam-style question on how RNA differs from DNA. Students will learn that RNA is shorter than DNA and this leads into the final part of the lesson where mRNA and tRNA are introduced and again they are challenged to use the new information explain the difference in size. Brief details of transcription and then translation are provided so that students are prepared for the upcoming lessons on protein synthesis.

This fully-resourced lesson describes how DNA is replicated during interphase of the cell cycle and explains why it is known as semi-conservative replication. Both the detailed PowerPoint and accompanying resources have been designed to cover the details of point 2.1.3 (e) of the OCR A-level Biology A specification and the occurrence of spontaneous mutations is also discussed in the latter part of the lesson. As detailed in the specification, the focus of this lesson is the role of the enzymes DNA helicase and polymerase and students are also introduced to DNA ligase to enable them to understand how this enzyme functions to join the nucleic acid fragments. Time is taken to explain key details such as the assembly of strands in the 5’-to-3’ direction so that the continuous manner in which the leading strand is synthesised can be compared against that of the lagging strand. The students are constantly challenged to make links to previous topics such as DNA structure, phosphorylated nucleotides and hydrolysis reactions through a range of exam questions and answers are displayed so any misconceptions are quickly addressed. The final part of the lesson focuses on the occurrence of mistakes by DNA polymerase and also on the quantity of DNA in the cell following replication so that future links can be made to the cell cycle (as covered in module 2.1.6)

This is a detailed and engaging lesson that looks at how molecules move between areas of differing concentrations by diffusion and then explores how this occurs across cell membranes and focuses on the alveoli. The lesson begins by using a step by step format to write the definition for diffusion so that key terms such as concentration gradient are understood. Students will be introduced to this as a passive process so that they can understand how active transport differs when this is met in another lesson. Progress checks are written into the lesson at regular intervals so that students can assess their understanding against a displayed answer. Moving forwards, the lesson focuses on diffusion across cell membranes and uses the example of the exchange surface of the alveoli and blood capillaries to explore the different features which act to increase the rate of diffusion. The final part of the lesson briefly looks at how the villi in the small intestine increase the rate of diffusion. This lesson has been written for GCSE aged students. If you’re looking for a lesson on this topic but for older students, then my alternative upload “Simple diffusion” will be more suitable

This is a concise, fast-paced lesson that has been designed to enable students to discover the key structural features of a synapse and be able to write accurate descriptions of the sequence of events that occur at these structures. The neurotransmitter involved is acetyl choline and therefore this is specifically a lesson about cholinergic synapses. The lesson begins by going through the terminology associated with synapses which includes pre-synaptic terminal or knob, synaptic cleft and post-synaptic neurone. Then time is taken to look at each of the two neurones and the structures found inside the terminal or on the membranes. The main task of the lesson involves a step by step guide through the sequence of events at the synapse. This guide has been written in a bullet point format and students are challenged to use the features they have met and their own Biological knowledge to complete each point. The final part of the lesson looks at how the enzyme acetylcholinesterase is involved in the breakdown and then how the neurotransmitter is re-formed using the ATP generated in the mitochondria This lesson is written for A-level students

This is a fully-resourced revision lesson that uses a combination of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content found within Module 2.1.1 (Cell structure) of the OCR A-level Biology A specification. The sub-topics and specification points that are tested within the lesson include: The use of microscopy to observe and investigate different types of cells The use and manipulation of the magnification formula The difference between magnification and resolution The ultrastructure of eukaryotic cells and the function of the different cellular components Interpretation of electron microscope images The interrelationship between the organelles involved in the production and secretion of proteins The similarities and differences in the structure and ultrastructure of prokaryotic and eukaryotic cells Students will be engaged through the numerous quiz rounds such as “It doesn’t HURT to CONVERT” and “Word association game” whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual A-level terminal exams

This is a fully-resourced REVISION lesson that uses a combination of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content found within Topic 5 (Energy transfers in and between organisms) of the AQA A-level Biology specification. The sub-topics and specification points that are tested within the lesson include: The light dependent reaction including the production of ATP and reduced NADP and the photolysis of water The light-independent reaction to form triose phosphate and regenerate RuBP Identify environmental factors that limit the rate of photosynthesis Glycolysis as the first stage of both aerobic and anaerobic respiration The conversion of pyruvate to lactate The stages of aerobic respiration that occur in the mitochondria Losses of energy through food chains The roles of microorganisms in the nitrogen cycle The environmental issues of the use of fertilisers as seen with eutrophication Students will be engaged through the numerous quiz rounds such as “Can you DEPEND on your knowledge” and “Are you on the right PATH” whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual A-level terminal exams

This is an engaging and fully-resourced revision lesson which uses a range of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content within topic 8 (Exchange and transport in animals) of the Edexcel GCSE Biology 9-1 specification. The specification points that are covered in this revision lesson include: Explain the need for exchange surfaces and a transport system in multicellular organisms including the calculation of surface area : volume ratio Explain how alveoli are adapted for gas exchange by diffusion between air in the lungs and blood in capillaries Describe the factors affecting the rate of diffusion, including surface area, concentration gradient and diffusion distance Explain how the structure of the blood is related to its function Explain how the structure of the blood vessels is related to their function Explain how the structure of the heart and circulatory system is related to its function, including the role of the major blood vessels, the valves Describe cellular respiration as an exothermic reaction which occurs continuously in living cells to release energy for metabolic processes, including aerobic and anaerobic respiration Compare the process of aerobic respiration with the process of anaerobic respiration Calculate heart rate, stroke volume and cardiac output, using the equation cardiac output = stroke volume × heart rate The students will thoroughly enjoy the range of activities, which include quiz competitions such as Where’s LENNY?” where they compete to recognise the blood vessel being described from the clues whilst crucially being able to recognise the areas of this topic which need their further attention. This lesson can be used as revision resource at the end of the topic or in the lead up to mocks or the actual GCSE exams.