This is a highly-detailed revision resource which has been designed to be used over a number of lessons and allows teachers to dip in and out of the material as fits to the requirements of their classes and students. The resource consists of an engaging and detailed powerpoint (135 slides) and worksheets which have been differentiated to allow students of differing abilities to be challenged and access the work. The lesson consists of a wide range of activities which will engage and motivate the students and includes exam questions, quiz competitions and quick tasks. The lesson has been designed to cover as many of the sub-topics within topics 4, 5 and 6 of the OCR Gateway GCSE Biology A specification but the following sub-topics have been given particular attention: Topic B4: Community-level systems Ecological terms Carbon cycle Topic B5: Genes, inheritance and selection The effect of mutations on phenotypes Single-gene crosses Sex determination Genetic terminology Topic B6: Global challenges Communicable diseases Genetic engineering Vaccinations CHD This revision resource can be used in the lead up to mocks or the actual GCSE exams and due to its size, it could be repeatably used to ensure that students develop a deep understanding of these topics.

This detailed lesson describes how the Link reaction and the Krebs cycle, that take place in the matrix, result in the complete oxidation of pyruvate. The PowerPoint and the accompanying resource have been designed to cover points 5.3 (i) & (ii) of the Edexcel A-level Biology B specification and describes how these reactions result in carbon dioxide, reduced NAD (and FAD) and ATP The lesson begins with a challenge, where the students have to recall the details of glycolysis in order to form the word matrix. This introduces the key point that these two stages occur in this part of the mitochondria and time is taken to explain why the reactions occur in the matrix as opposed to the cytoplasm like glycolysis. Moving forwards, the Link reaction is covered in 5 detailed bullet points and students have to add the key information to these points using their prior knowledge as well as knowledge provided in terms of NAD. The students will recognise that this reaction occurs twice per molecule of glucose and a quick quiz competition is used to test their understanding of the numbers of the different products of this stage. This is just one of the range of methods that are used to check understanding and all answers are explained to allow students to assess their progress. The rest of the lesson focuses on the Krebs cycle. In line with the detail of the specification, students will understand how decarboxylation and dehydrogenation reactions result in the regeneration of the oxaloacetate It is estimated that it will take about 2 hours of A-level teaching time to cover the detail of the lesson and therefore the detail of the specification point 5.3

This detailed lesson describes the different levels of protein structure and focuses on the bonds that hold these molecules in shape. Both the engaging PowerPoint and accompanying resources have been designed to cover point (i) as detailed in AS unit 1, topic 1 of the WJEC A-level Biology specification and makes continual links to previous lessons such as amino acids & peptide bonds as well as to upcoming lessons like enzymes and antibodies. The start of the lesson focuses on a gene as a sequence of bases that code for the amino acid sequence in a polypeptide and a step by step guide is used to demonstrate how the sequences of bases in a gene acts as a template to form a sequence of codons on a mRNA strand and how this is translated into a particular sequence of amino acids known as the primary structure. The students are then challenged to apply their understanding of this process by using three more gene sequences to work out three primary structures and recognise how different genes lead to different sequences. Moving forwards, students will learn how the order of amino acids in the primary structure determines the shape of the protein molecule, through its secondary, tertiary and quaternary structure and time is taken to consider the details of each of these. There is a particular focus on the different bonds that hold the 3D shape firmly in place and a quick quiz round then introduces the importance of this shape as exemplified by enzymes, antibodies and hormones. Students will see the differences between globular and fibrous protein and again biological examples are used to increase relevance. The lesson concludes with one final quiz round called STRUC by NUMBERS where the students have to use their understanding of the protein structures to calculate a numerical answer.

An engaging lesson presentation (66 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within module B3 of the OCR Gateway A GCSE Combined Science specification. The topics that are tested within the lesson include: Nervous system Reflexes Hormones Negative feedback The menstrual cycle Controlling reproduction Using hormones to treat infertility Students will be engaged through the numerous activities including quiz rounds like "From Numbers 2 LETTERS" and "Take the IVF Hotseat" whilst crucially being able to recognise those areas which need further attention

This lesson describes the effects of gene mutations can have on amino acid sequences, as illustrated by sickle cell anaemia. The engaging and detailed PowerPoint and accompanying resources are part of the first lesson in a series of 2 lessons which have been designed to cover point (f) in topic 3 of A2 unit 4 of the WJEC A-level Biology specification and includes substitutions, deletions and insertions In order to understand how a change in the base sequence can affect the order of the amino acids, students must be confident in their understanding and application of protein synthesis which was covered earlier in this topic. Therefore, the start of the lesson focuses on transcription and translation and students are guided through the use of the codon table to identify amino acids. Moving forwards, a task called known as THE WALL is used to introduce to the names of three types of gene mutation whilst challenging the students to recognise three terms which are associated with the genetic code. The main focus of the lesson is substitutions and how these mutations may or may not cause a change to the amino acid sequence. The students are challenged to use their knowledge of the degenerate nature of the genetic code to explain how a silent mutation can result. Students will learn that a substitution is responsible for the new allele that causes sickle cell anaemia and they are tested on their understanding through an exam-style question. As with all of the questions, a mark scheme is included in the PowerPoint which can be displayed to allow the students to assess their understanding. The rest of the lesson looks at base deletions and base insertions and students are introduced to the idea of a frameshift mutation. One particular task challenges the students to evaluate the statement that base deletions have a bigger impact on primary structure than base substitutions. This is a differentiated task and they have to compare the fact that the reading frame is shifted by a deletion against the change in a single base by a substitution

This is a fully-resourced and engaging REVISION LESSON which challenges the students on their knowledge and understanding of the content of module 2.1.2 (Biological molecules) of the OCR A-level Biology A specification. As this topic tends to be poorly understood by students, the lesson has been designed to include a wide range of activities that include differentiated exam questions, quick tasks and quiz competitions which will engage the students whilst they assess their progress. It has been designed to cover as much of the specification as possible but the following sub-topics have received particular attention: Formation of polysaccharides by glycosidic bonds between monomers Recognising monosaccharides, disaccharides and polysaccharides The structure of starch and glycogen in relation to their function as stores and providers of energy Water as a solvent with a high specific heat capacity and a high specific latent heat of vaporisation Structure and bonding in proteins The structure of globular and fibrous proteins as demonstrated by haemoglobin and collagen The structure and function of cellulose Links are made to other topics so that students are able to see how questions can include parts from different Biological concepts

This is a fully-resourced lesson which uses exam-style questions, engaging quiz competitions, quick tasks and discussion points to challenge students on their understanding of the content of topics B1 & B6 - B9, that will assessed on PAPER 2. It has been specifically designed for students on the Pearson Edexcel GCSE Combined Science course who will be taking the FOUNDATION TIER examinations but is also suitable for students taking the higher tier who need to ensure that the key points of each of the sub-topics are embedded. The lesson has been written to take place in numerous shops that could be found on the high street as well as at an urban park to allow the following sub-topics to be covered: Eukaryotes and prokaryotes The prefixes of size and converting between units The cell structures of animal and plant cells The structure of the heart and the circulatory system The features of the alveoli which enable efficient gas exchange Calculating cardiac output Temperature and photosynthesis The role of enzymes in reactions The functions of the components of blood The homeostatic control of blood glucose by insulin secretion Diabetes type I and II Calculating BMI and the link between obesity and diabetes type II The hormones involved in the menstrual cycle The different methods of contraception Estimating population size using sampling results The carbon cycle In order to maintain challenge whilst ensuring that all abilities can access the questions, the majority of the tasks have been differentiated and students can ask for extra support when they are unable to begin a question. Due to the extensiveness of this revision lesson, it is estimated that it will take in excess of 3/4 teaching hours to complete the tasks and therefore this can be used at different points throughout the duration of the course as well as acting as a final revision before the PAPER 2 exam

This is an engaging revision lesson which uses a range of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content within topic 6 (Groups in the Periodic Table) of the Edexcel GCSE Chemistry specification. The specification points that are covered in this revision lesson include: Explain why some elements can be classified as alkali metals (group 1), halogens (group 7) or noble gases (group 0), based on their position in the periodic table Describe the pattern in reactivity of the alkali metals, lithium, sodium and potassium, with water; and use this pattern to predict the reactivity of other alkali metals Explain this pattern in reactivity in terms of electronic configurations Recall the colours and physical states of chlorine, bromine and iodine at room temperature Describe the pattern in the physical properties of the halogens, chlorine, bromine and iodine, and use this pattern to predict the physical properties of other halogens Describe the reactions of the halogens, chlorine, bromine and iodine, with metals to form metal halides, and use this pattern to predict the reactions of other halogens Describe the relative reactivity of the halogens chlorine, bromine and iodine, as shown by their displacement reactions with halide ions in aqueous solution, and use this pattern to predict the reactions of astatine Explain the relative reactivity of the halogens in terms of electronic configurations Explain why the noble gases are chemically inert, compared with the other elements, in terms of their electronic configurations The students will thoroughly enjoy the range of activities, which include quiz competitions such as “Make sure you check every passage PERIODICALLY” where they have to scan summary passages about the table and decide if it is 100% correct whilst crucially being able to recognise the areas of this topic which need their further attention. This lesson can be used as revision resource at the end of the topic or in the lead up to mocks or the actual GCSE exams

This fully-resourced lesson describes the roles of the SAN, AVN, the bundle of His and Purkyne tissue in the coordination of the heartbeat. The PowerPoint and accompanying resources have been designed to cover points 7.12 (i) & (ii) of the Edexcel International A-level Biology specification and also describes the myogenic nature of cardiac muscle. The lesson begins with the introduction of the SAN as the natural pacemaker and then time is given to study each step of the conduction of the impulse as it spreads away from the myogenic tissue in a wave of excitation. The lesson has been written to make clear links to the cardiac cycle and the structure of the heart and students are challenged on their knowledge of this system from topic 1. Moving forwards, students are encouraged to consider why a delay would occur at the AVN and then they will learn that the impulse is conducted along the Bundle of His to the apex so that the contraction of the ventricles can happen from the bottom upwards. The structure of the cardiac muscle cells is discussed and the final task of the lesson challenges the students to describe the conducting tissue, with an emphasis on the use of key terminology

This lesson describes the basic structure of mononucleotides and the resulting structural similarities and differences between DNA and RNA. The PowerPoint and accompanying resource have been designed to cover points 2.9 (i) and (ii) of the Edexcel International A-level Biology specification and makes regular links to upcoming lessons which cover DNA replication and protein synthesis. In a lesson in topic 1, the students were introduced to monosaccharides as an example of a monomer and were informed that a nucleotide was another example. In line with this, the start of the lesson challenges them to recognise the key term nucleotide when only the letters U, C and T are shown. The next part of the lesson describes the structure of a DNA nucleotide and an RNA nucleotide so that the pentose sugar and the bases adenine, cytosine and guanine can be recognised as similarities whilst deoxyribose and ribose and thymine and uracil are seen as the differences. Time is taken to discuss how a phosphodiester bond is formed between adjacent nucleotides and their prior knowledge and understanding of condensation reactions is tested through a series of questions. Students are then introduced to the purine and pyrimidine bases and this leads into the description of the double-helical structure of DNA and the hydrogen bonds between complementary bases. The final section of the lesson describes the structure of mRNA, tRNA and rRNA and students are challenged to explain why this single stranded polynucleotide is shorter than DNA In addition to the current understanding and prior knowledge checks, a number of quiz rounds have been written into the lesson to introduce key terms in a fun and memorable way and the final round acts as a final check on the structures of DNA and RNA.

This fully-resourced lesson explores how reproductive isolation can potentially lead to the formation of a new species by speciation . The engaging PowerPoint and accompanying resources have been designed to cover point 5.19 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification which states that students should understand how isolation reduces gene flow between populations which can lead to allopatric or sympatric speciation. The lesson begins by using the example of a hinny, which is the hybrid offspring of a horse and a donkey, to challenge students to recall the biological classification of a species. Moving forwards, students are introduced to the idea of speciation and the key components of this process, such as isolation and selection pressures, are covered and discussed in detail. Understanding and prior knowledge checks are included throughout the lesson to allow the students to not only assess their progress against the current topic but also to make links to earlier topics in the specification. Time is taken to look at the details of allopatric speciation and how the different mutations that arise in the isolated populations and genetic drift will lead to genetic changes. The example of allopatric speciation in wrasse fish because of the isthmus of Panama is used to allow the students to visualise this process. The final part of the lesson considers sympatric speciation and again a wide variety of tasks are used to enable a deep understanding to be developed.

This lesson focuses on the structure of RNA and specifically the similarities and differences between this nucleic acid and DNA. The engaging and detailed PowerPoint and accompanying resource have been designed to cover part 1 of point 4.2 of the AQA A-level Biology specification which states that students should be able to describe the structure of molecules of messenger RNA and transfer RNA as well as understand the concept of a genome and proteome. Students were introduced to the detailed structure of DNA in previous lessons covering specification point 4.1, so this lesson is written to tie in with those and continuously challenge prior knowledge as well as understanding of the current topic. The lesson begins with the introduction of the term genome and proteome and students are challenged to make the link between the genes in an organism and all of the proteins that can be produced by these sequence of bases. Moving forwards, students will learn that RNA is a member of the family of nucleic acids and therefore has a number of structural features that were previously seen in DNA. A quiz round called “A FAMILY AFFAIR” is used to challenge their knowledge of DNA to recognise those features that are also found on RNA such as the chain of linked nucleotides, pentose sugars, nitrogenous bases and phosphodiester bonds. The next task pushes them to consider features that have not been mentioned and therefore are differences as they answer a structured exam-style question on how RNA differs from DNA. Students will learn that RNA is shorter than DNA and this leads into the final part of the lesson where mRNA and tRNA are introduced and again they are challenged to use the new information explain the difference in size. Brief details of transcription and then translation are provided so that students are prepared for the upcoming lessons on protein synthesis.

This detailed and engaging lesson focuses on the importance of the excretion of carbon dioxide and urea in humans. It also looks at how the urea is formed as a result of deamination in the liver and as such covers the Core and Supplement content of the early section of topic 13 of the CIE IGCSE Biology specification. The lesson begins with a “Crack the code” type task which will enable the students to learn the meaning of excretion and specifically how it relates to the products of metabolism. Excretion is often confused with egestion by students so this misconception is addressed immediately and as a result they will understand that carbon dioxide and urea have to be excreted whereas faeces is egested. Moving forwards, time is taken to explain why carbon dioxide needs to be excreted and links are made to the earlier topic of enzymes and how a fall in pH could affect their activity. The rest of the lesson focuses on the formation of urea in the liver. Whilst learning about deamination, students will also be introduced to the process of assimilation and the production of rge plasma protein fibrinogen is used to explain the importance of this function of the liver. In addition to understanding checks and prior knowledge checks, quiz competitions are included in the lesson to introduce key terms in a fun and memorable way. This lesson has been designed for students studying the CIE IGCSE Biology course but is also suitable for older students who are starting the topic of excretion or the functions of the liver and want to recall the key facts.

This lesson describes the non-specific responses of the body to infection which include inflammation, lysozyme action, interferon and phagocytosis. The detailed PowerPoint and accompanying resources have been primarily designed to cover the content of point 6.8 of the Edexcel International A-level Biology specification but key details such as antigen-presentation are also introduced to prepare students for upcoming lessons on the immune response (6.9 & 6.10). At the start of the lesson, the students are challenged to recall that cytosis is a suffix associated with transport mechanisms and this introduces phagocytosis as a form of endocytosis which takes in pathogens and foreign particles. This emphasis on key terminology runs throughout the course of the lesson and students are encouraged to consider how the start or end of a word can be used to determine meaning. The process of phagocytosis is then split into 5 key steps and time is taken to discuss the role of opsonins as well as the fusion of lysosomes and the release of lysozymes. A series of application questions are used to challenge the students on their ability to make links to related topics including an understanding of how the hydrolysis of the peptidoglycan wall of a bacteria results in lysis. Students will be able to distinguish between neutrophils and monocytes from a diagram and at this point, the role of macrophages and dendritic cells as antigen-presenting cells is described so that it can be used in the next lesson. The importance of cell signalling for an effective immune response is discussed and the rest of the lesson focuses on the release of two chemicals - interferons and histamine. During the interferon section, references are made to a previous lesson on HIV structure and action so students can understand how the release of these signalling proteins helps neighbouring cells to heighten their anti-viral defences. A step by step guide is used to describe the release of histamine in the inflammatory response and the final task challenges students to use this support to form a detailed answer regarding the steps in inflammation.

This detailed lesson describes the transport of sodium and potassium ions in the maintenance of resting potential and how an action potential is formed. The engaging PowerPoint and accompanying resources have been designed to cover the detail included in points 9.5 (i) & (ii) of the Edexcel A-level Biology B specification. This topic is commonly assessed in the terminal exams so a lot of time has been taken to design this resource to include a wide range of activities that motivate the students whilst ensuring that the content is covered in the depth of detail that will allow them to have a real understanding. Interspersed within the activities are understanding checks and prior knowledge checks to enable the students to not only assess their progress against the current topic but also to challenge themselves on the links to earlier topics such as methods of movements across cell membranes. There are also a number of quiz competitions which are used to introduce key terms and values in a fun and memorable way and discussion points to encourage the students to consider why a particular process or mechanism occurs. Over the course of the lesson, the students will learn and discover how the movement of ions across the membrane causes the membrane potential to change. They will see how the resting potential is maintained through the use of the sodium/potassium pump and potassium ion leakage. There is a real focus on depolarisation to allow students to understand how generator potentials can combine and if the resulting depolarisation then exceeds the threshold potential, a full depolarisation will occur. At this point in the lesson students will discover how the all or nothing response explains that action potentials have the same magnitude and that instead a stronger stimulus is linked to an increase in the frequency of the transmission. The rest of the lesson challenges the students to apply their knowledge to explain how repolarisation and hyperpolarisation result and to suggest advantages of the refractory period for nerve cells.

This is a fully-resourced revision lesson that uses a combination of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content found within Topic 5 (Atomic Physics) of the CIE IGCSE Physics specification The sub-topics and specification points (from both the core and supplement sections), that are tested within this revision lesson include: Atomic model Nucleus Detection of radioactivity Characteristics of the three kinds of emission Radioactive decay Half-life Students will be engaged through the numerous quiz rounds whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual exams

This detailed lesson outlines the characteristics features of the kingdoms Protoctista, Fungi, Plantae and Animalia. The engaging PowerPoint and accompanying resources have been designed to cover point 18.2 [c] of the CIE International A-level Biology specification which states that students should be able to describe the features of these four eukaryotic kingdoms. This lesson begins with a knowledge recall as students have to recognise that prior to 1990, kingdom was the highest taxa in the classification hierarchy. Moving forwards, they will recall the names of the five kingdoms and immediately be challenged to split them so that the prokaryotae kingdom is left on its own. The features of this kingdom are given so that the lesson can focus on the four eukaryotic kingdoms. Students are constantly challenged on their understanding of the current topic as well as that of earlier topics, as demonstrated by a differentiated task about the structure and function of cellulose which was covered in topic 2. This task is found in the section of the lesson where the main constituent of the wall can be used to distinguish between plantae, fungi and prokaryotae. Quick quiz competitions, such as SAY WHAT YOU SEE are used to introduce key terms in a fun and memorable way. The final part of the lesson looks at the protoctista kingdom and students will come to understand how these organisms tend to share a lot of animal or plant-like features.

This fully-resourced lesson will prepare students for the range of mathematical-based questions that they may face on Paper 2 & 4. It is specificallly designed for students who have studied the Extended subject content (Core & Supplement) as detailed on the CIE IGCSE Chemistry specification. The lesson contains a wide range of activities which includes 8 quiz competition rounds spread across the duration of the lesson to maintain engagement whilst the students assess their understanding. The mathematical skills covered in this lesson include: Calculating the number of sub-atomic particles in atoms and ions Writing chemical formulae for ionic compounds Identifying isotopes Using Avogadro’s constant to calculate the number of particles Calculating the relative formula mass Calculating amount in moles using the mass and the relative formula mass Balancing chemical symbol equations Calculating reacting masses Gas calculations using molar volume Calculating concentration of solutions Titration calculations Deducing the empirical formula Calculating energy changes in reactions Most of the resources have been differentiated two ways to allow students of differing abilities to access the work whilst still being challenged. In addition, step by step guides are used to demonstrate how to carry out some of the more difficult calculations such as the harder mole calculations and calculating masses in reactions. Due to the extensiveness of this lesson, it is estimated that it will take in excess of 3 teaching hours to complete all of the tasks and questions

Students commonly confuse the two forms of cell division, so this revision lesson has been designed to address those mistakes and misconceptions. The PowerPoint and accompanying resources have been planned to challenge the students on their understanding of the details of points 1.2.1, 1.2.2 and 6.1.2 of the AQA GCSE biology and combined science specifications. The lesson goes through each of the three stages of the cell cycle including mitosis, to ensure that students can describe the key events and state the outcome in terms of the daughter cells. The lesson contains a series of tasks which include exam questions, discussions and a quiz which allow the students to assess their understanding. The final part of the lesson focuses on meiosis and specifically the differences to mitosis in terms of the number of cell divisions, the gametes formed, and their genetic make up. This lesson has been designed to be used for revision purposes in the lead up to the GCSE exams or in preparation for an end of topic test or mocks.

An engaging lesson presentation (73 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit C5 of the OCR Gateway A GCSE Chemistry specification. The topics that are tested within the lesson include: Percentage yield Concentration of solution Titrations Titration calculations Gas calculations Rate of reaction Factors affecting the rate of reaction Reversible reactions Equilibrium position Students will be engaged through the numerous activities including quiz rounds like “Under PRESSURE” and “Number CRAZY” whilst crucially being able to recognise those areas which need further attention