A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
This lesson describes and explains how increasing the concentration of inhibitors affects the rate of an enzyme-controlled reaction. The PowerPoint and accompanying resource are the last in a series of 5 lessons which cover the content detailed in point 1.4.2 of the AQA A-level Biology specification and describes the effect of both competitive and non-competitive inhibitors.
The lesson begins with a made up round of the quiz show POINTLESS called “Biology opposites” and this will get the students to recognise that inhibition is the opposite of stimulation. This introduces inhibitors as substances that reduce the rate of a reaction and students are challenged to use their general knowledge of enzymes to identify that inhibitors prevent the formation of the enzyme-substrate complex. Moving forwards, a quick quiz competition generates the abbreviation EIC (representing enzyme-inhibitor complex) and this introduces competitive inhibitors as substances that occupy the active site. The students are asked to apply their knowledge to a new situation to work out that these inhibitors have a similar shape to the enzyme’s substrate molecule. A series of exam-style questions are used throughout the lesson and at this point, the students are challenged to work out that an increase in the substrate concentration would reduce the effect of a fixed concentration of a reversible competitive inhibitor. The rest of the lesson focuses on non-competitive inhibitors and time is taken to ensure that key details such as the disruption of the tertiary structure is understood and biological examples are used to increase the relevance. Again, students will learn that increasing the concentration of the inhibitor results in a greater inhibition and a reduced rate of reaction but that increasing the substrate concentration cannot reduce the effect as was observed with competitive inhibitors.
This lesson describes how the immune system uses molecules on the surface of a cell to identify it, focusing on the identification of pathogens by their antigens. The PowerPoint and accompanying resources which are differentiated are part of the 1st lesson in the series of 7 that cover the content detailed in topic 2.4 of the AQA A-level Biology specification. As this is the first lesson in topic 2.4, it has been specifically planned to introduce a number of key concepts which include phagocytosis, T and B cells, antibodies and memory cells so that students are prepared for upcoming lessons.
The lesson begins by challenging the students to use their knowledge of cells to recall the common internal components of a cell before they are informed that all cells also have molecules on their outer membrane. Students will recognise that these molecules are used by the immune system for identification before a quick quiz competition reveals that this allows toxins, abnormal body cells and pathogens to be identified. Moving forwards, the next part of the lesson focuses on the antigens that are found on the outside of a pathogen and links are made to upcoming lesson topics which include:
phagocytosis following the identification of a pathogen
antigen-presentation by macrophages and dendritic cells
production of antibodies which are specific to the antigens
the use of antigens in a vaccination program
The final task challenges the students to describe and explain how antigen variability will affect disease and disease prevention and this task has been differentiated two ways to allow students of differing abilities to be challenged and supported.
This lesson describes the mode of actions of macrophages, neutrophils and lymphocytes. The engaging PowerPoint and accompanying resource have been primarily designed to cover point 6.7 (i) of the Edexcel A-level Biology B specification but includes an introduction to antigen-presentation so that the students are prepared for upcoming lessons on the cell-mediated and humoral responses.
At the start of the lesson, the students are challenged to recall that cytosis is a suffix associated with transport mechanisms and this introduces phagocytosis as a form of endocytosis which takes in pathogens and foreign particles. This emphasis on key terminology runs throughout the course of the lesson and students are encouraged to consider how the start or end of a word can be used to determine meaning. The process of phagocytosis is then split into 5 key steps and time is taken to discuss the role of opsonins as well as the fusion of lysosomes and the release of lysozymes. A series of application questions are used to challenge the students on their ability to make links to related topics including an understanding of how the hydrolysis of the peptidoglycan wall of a bacteria results in lysis. Students will be able to distinguish between neutrophils and monocytes from a diagram and at this point, the role of macrophages and dendritic cells as antigen-presenting cells is described so that it can be used in the next lesson. The lesson concludes with an introduction to lymphocytes so that initial links between phagocytosis and the specific immune responses are made.
This lesson describes the role of the hypothalamus and the mechanisms of thermoregulation that maintain the body in dynamic equilibrium during exercise. The PowerPoint has been designed to cover point 7.12 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification.
Students were introduced to homeostasis at GCSE and this lesson has been written to build on that knowledge and to add the key detail needed at this level. Focusing on the three main parts of a homeostatic control system, the students will learn about the role of the internal and peripheral thermoreceptors, the thermoregulatory centre in the hypothalamus and the range of effectors which bring about the responses to restore optimum levels.
The following responses are covered in this lesson:
Vasodilation
Increased sweating
Body hairs
In each case, time is taken to challenge students on their ability to make links to related topics such as the arterioles involved in the redistribution of blood and the high specific latent heat of vaporisation of water.
This lesson describes and explains how production is affected by a range of farming practices designed to increase the efficiency of energy transfer. The PowerPoint and accompanying resources are part of the third lesson in a series of 3 which have been designed to cover the detail included in specification point 5.3 of the AQA A-level Biology specification.
Over the course of the lesson, a range of tasks which include exam-style questions with displayed mark schemes, guided discussion periods and quick quiz competitions will introduce and consider the following farming practices:
raising herbivores to reduce the number of trophic levels in a food chain
intensely rearing animals to reduce respiratory losses in human food chains
the use of fungicides, insecticides and herbicides
the addition of artificial fertilisers
The ethical issues raised by these practices are also considered and alternative methods discussed such as the addition of natural predators and the use of organic fertilisers like manure
As this is the last lesson in topic 5.3, it has been specifically planned to challenge the students on their knowledge of the previous two lessons and this includes a series of questions linking farming practice to the formula to calculate net production
This detailed lesson describes how the ventilation rate is controlled by the ventilation centre in the medulla oblongata. The engaging PowerPoint and accompanying resource have been designed to cover the second part of point 7.13 (ii) in unit 5 of the Edexcel International A-level Biology specification.
The previous lesson described the control of heart rate so this lesson has been written to tie in with this and to use this knowledge to further the students understanding of the control of ventilation rate. The lesson begins with a focus on the muscles involved in ventilation, specifically the diaphragm and external intercostal muscles, so that students can understand how their contraction results in an increase in the volume of the thoracic cavity. Boyle’s law is briefly introduced to allow students to recognise the relationship between volume and pressure so that the movement of air with the pressure gradient can be described. Time is then taken to consider the importance of inhalation and an exam-style question challenges the students to explain that a constant supply of oxygen to the alveoli is needed to maintain a steep concentration gradient with the surrounding capillaries. The students are then tasked with writing a description of exhalation at rest using the description of inhalation as their guide. The rest of the lesson focuses on the mechanisms involved in increasing the rate and depth of breathing during exercise. Students will use their knowledge of the control of heart rate to recall that chemoreceptors detect changes in oxygen and carbon dioxide and blood pH and that the medulla oblongata processes the sensory information that it receives before coordinating a response. The final task challenges them to use the information provided in this lesson and the previous one to order 10 detailed descriptions so they can form a complete passage about this control system
This bundle of 4 lessons covers the content of module 5.1.1 of the OCR A-level Biology A specification, titled communication and homeostasis. As this module tends to be one of the first to be taught in the second year of the course, it’s extremely important that links are made to upcoming topics as well as challenging the students on their prior knowledge of modules 2 - 4. This is achieved through a wide range of tasks, that include exam-style questions, differentiated tasks and guided discussion periods. Quick quiz competitions are also used to introduce key terms and values in a fun and memorable way.
The following specification points are covered by the 4 lesson PowerPoints and accompanying resources included in this bundle:
The communication between cells by cell signalling
The principles of homeostasis
The differences between negative and positive feedback
The physiological and behavioural responses involved in temperature control in endotherms and ectotherms
As detailed above, these lessons have been specifically planned to tie in with the other parts of module 5, including neuronal communication, hormonal communication and animal and plant responses.
If you would like to sample the quality of the lessons in this bundle, then download the principles of homeostasis and temperature control in ectotherms lessons as these have been uploaded for free
This lesson describes the processes that take place during interphase, mitosis and cytokinesis and outlines how checkpoints regulate the cell cycle. The PowerPoint and accompanying resources have been designed to cover points 2.1.6 (a & b) of the OCR A-level Biology specification and prepares the students for the upcoming lessons on the main stages of mitosis and its significance in life cycles
The students were introduced to the cell cycle at GCSE so this lesson has been planned to build on that knowledge and to emphasise that the M phase which includes mitosis (nuclear division) only occupies a small part of the cycle. The students will learn that interphase is the main stage and that this is split into three phases, G1, S and G2. A range of tasks which include exam-style questions, guided discussion points and quick quiz competitions are used to introduce key terms and values and to describe the main processes that occur in a very specific order. There is also a focus on the checkpoints, such as the restriction point that occurs before the S phase to ensure that the cell is ready for DNA replication. Extra time is taken to ensure that key terminology is included and understood, such as sister chromatid and centromere, and this focus helps to show how it is possible for genetically identical daughter cells to be formed at the end of the cycle. Important details of mitosis are introduced so students are ready for the next lesson, before the differences in cytokinesis in animal and plant cells are described.
This lesson describes the main stages of meiosis, focusing on the events which contribute to genetic variation and explains its significance in life cycles. The detailed PowerPoint and accompanying resources have been designed to cover points 2.1.6 (f) & (g) of the OCR A-level Biology A specification and includes description of crossing over, independent assortment, independent segregation and the production of haploid gametes
In order to understand how the events of meiosis like crossing over and independent assortment and independent segregation can lead to variation, students need to be clear in their understanding that DNA replication in interphase results in homologous chromosomes as pairs of sister chromatids. Therefore the beginning of the lesson focuses on the chromosomes in the parent cell and this first part of the cycle and students will be introduced to non-sister chromatids and the fact that they may contain different alleles which is important for the exchange that occurs during crossing over. Time is taken to go through this event in prophase I in a step by step guide so that the students can recognise that the result can be new combinations of alleles that were not present in the parent cell. Moving forwards, the lesson explores how the independent assortment and segregation of chromosomes and chromatids during metaphase I and II and anaphase I and II respectively results in genetically different gametes. The key events of all of the 8 phases are described and there is a focus on key terminology to ensure that students are able to describe genetic structures in the correct context. The final part of the lesson looks at the use of a mathematical expression to calculate the possible combinations of alleles in gametes as well as in a zygote following the random fertilisation of haploid gametes. Understanding and prior knowledge checks are interspersed throughout the lesson as well as a series of exam-style questions which challenge the students to apply their knowledge to potentially unfamiliar situations.
This lesson has been specifically planned to lead on from the previous two lessons on the cell cycle and the main stages of mitosis and constant references are made throughout to encourage students to make links and also to highlight the differences between the two types of nuclear division
Meiosis, genetic inheritance and the control of gene expression are some of the harder topics on this A-level Biology course and all three are covered in topic 16 (Inherited change) of the CIE A-level Biology specification. The 10 lessons included in this bundle have been planned at length and contain a wide range of tasks that cover the detailed content whilst checking on understanding and key terms and values are introduced through engaging quiz competitions.
The following topic 16 specification points are covered by these lessons:
Topic 16.1
The meaning of a homologous pair of chromosomes
The behaviour of chromosomes in animal and plant cells during meiosis
Genetic variation is caused by crossing over, random assortment and the random fusion of gametes at fertilisation
Topic 16.2
The meaning of key genetic terms
Using genetic diagrams to solve problems involving mohohybrid and dihybrid crosses, including those involving autosomal linkage, sex linkage, codominance, multiple alleles and gene interactions
Use the chi-squared test to test the significance of differences between observed and expected results
Gene mutations occur by substitution, deletion and insertion and may affect the phenotype
Topic 16.3
The genetic control of protein production in a prokaryote as shown by the lac operon
The function of transcription factors in gene expression in eukaryotes
Gibberellins and DELLA protein repressors
If you would like to sample the quality of the lessons included in this bundle, then download the autosomal linkage and chi-squared test lessons as these have been uploaded for free
The mathematical element of the OCR A-level Biology A specification is substantial and every year, there are a large number of exam questions that require the application of a range of mathematical skills. Therefore, a clear understanding of how and when to apply these skills is closely related to success on this course and the following calculations are covered by the 9 lessons that are included in this bundle:
Using the chi-squared test to determine significance between the observed and expected results of a genetic cross
Using the Hardy Weinberg principle to calculate the frequency of an allele or a genotype in a population
Calculating the standard deviation to measure the spread of data
Using the Student’s t-test to compare the means of two sets of data
Calculating the temperature coefficient
Calculating the proportion of polymorphic gene loci
Using and interpreting Simpson’s index of diversity to calculate the biodiversity of a habitat
Using the Spearman’s rank correlation coefficient to consider the relationship of the data
The use and manipulation of the magnification formula
A revision lesson is also included in this bundle which acts as a fun and engaging revision of the range of calculations
This lesson describes the relationship between the size of an organism or structure and its surface to volume ratio. The PowerPoint and accompanying worksheets have been designed to cover point 3.1 of the AQA A-level Biology specification and also have been specifically planned to prepare the students for the upcoming lessons in topic 3 on gas exchange and absorption in the ileum.
The students are likely to have been introduced to the ratio at GCSE, but understanding of its relevance tends to be mixed. Therefore, real life examples are included throughout the lesson that emphasise the importance of the surface area to volume ratio in order to increase this relevance. A lot of students worry about the maths calculations that are associated with this topic so a step by step guide is included at the start of the lesson that walks them through the calculation of the surface area, the volume and then the ratio. Through worked examples and understanding checks, SA/V ratios are calculated for cubes of increasing side length and living organisms of different size. These comparative values will enable the students to conclude that the larger the organism or structure, the lower the surface area to volume ratio. A differentiated task is then used to challenge the students to explain the relationship between the ratio and the metabolic demands of an organism and this leads into the next part of the lesson, where the adaptations of larger organisms to increase the ratio at their exchange surfaces is covered. The students will calculate the SA/V ratio of a human alveolus (using the surface area and volume formulae for a sphere) and will see the significant increase that results from the folding of the membranes. This is further demonstrated by the villi and the microvilli on the enterocytes that form the epithelial lining of these folds in the ileum. The final part of the lesson introduces Fick’s law of diffusion so that students are reminded that the steepness of a concentration gradient and the thickness of a membrane also affect the rate of diffusion.
This lesson bundle contains 16 lessons which have been designed to cover the Edexcel International A-level Biology specification points which focus on the structure of DNA and RNA, their roles in replication and protein synthesis, and genetics and inheritance. The lesson PowerPoints are highly detailed, and along with their accompanying worksheets, they have been planned at length to contain a wide range of engaging tasks which cover the following A-level Biology content found in topics 2, 3 and 6 of the course:
2.9 (i): Know the basic structure of mononucleotides (deoxyribose or ribose linked to a phosphate and a base, including thymine, uracil, adenine, cytosine or guanine) and the structures of DNA and RNA (polynucleotides composed of mononucleotides linked by condensation reactions to form phosphodiester bonds)
2.9 (ii): Know how complementary base pairing and the hydrogen bonding between two complementary strands are involved in the formation of the DNA double helix
2.10 (i): Understand the process of DNA replication, including the role of DNA polymerase
2.11: Understand the nature of the genetic code
2.12: Know that a gene is a sequence of bases on a DNA molecule that codes for a sequence of amino acids in a polypeptide chain
2.13 (i): understand the process of protein synthesis (transcription and translation), including the role of RNA polymerase, translation, messenger RNA, transfer RNA, ribosomes and the role of start and stop codons
2.13 (ii): Understand the roles of the DNA template (antisense) strand in transcription, codons on messenger RNA and anticodons on transfer RNA
2.14 (i): Understand how errors in DNA replication can give rise to mutations (substitution, insertion and deletion of bases)
2.14 (ii): Know that some mutations will give rise to cancer or genetic disorders, but that many mutations will have no observable effect
2.15 (i): Know the meaning of the terms: gene, allele, genotype, phenotype, recessive, dominant, codominance, homozygote and heterozygote
2.15 (ii): Understand patterns of inheritance, including the interpretation of genetic pedigree diagrams, in the context of monohybrid inheritance
2.15 (iii): Understand sex linkage on the X chromosome, including red-green colour blindness in humans
2.16: Understand how the expression of a gene mutation in people with cystic fibrosis impairs the functioning of the gaseous exchange, digestive and reproductive systems
2.17 (i): Understand the uses of genetic screening, including the identification of carriers, pre-implantation genetic diagnosis (PGD) and prenatal testing, including amniocentesis and chorionic villus sampling
2.17 (ii): Understand the implications of prenatal genetic screening
3.9 (i): Know that a locus is the location of genes on a chromosome
3.9 (ii): Understand the linkage of genes on a chromosome
3.18: Understand how cells become specialised through differential gene expression, producing active mRNA, leading to the synthesis of proteins which, in turn, control cell processes or determine cell structure in animals and plants
3.19: Understand how one gene can give rise to more than one protein through posttranscriptional changes to messenger RNA (mRNA).
3.20 (i): Phenotype is an interaction between genotype and the environment
3.21: Understand how some phenotypes are affected by multiple alleles for the same gene at many loci (polygenic inheritance) as well as the environment and how this can give rise to phenotypes that show continuous variation
6.17: Know how DNA can be amplified using the polymerase chain reaction (PCR)
This lesson outlines how penicillin acts on bacteria and why antibiotics do not affect viruses. The PowerPoint and accompanying resources have been designed to cover point 10.2 (a) of the CIE A-level Biology specification and also introduces the concept of bactericidal and bacteriostatic antibiotics, as illustrated by penicillin and tetracycline.
The lesson begins with an engaging task, where the students have to identify the surnames of famous scientists from their descriptions to reveal the surname Fleming. This introduces Sir Alexander Fleming as the microbiologist who discovered penicillin in 1928. Time is taken to describe penicillin as a group of antibiotics that contain a beta-lactam ring in their molecular structure. Using this information and their knowledge of bacterial cell structure from topic 1, the students have to complete a passage describing how penicillin inhibits the formation of cross links in cell wall synthesis. A series of exam-style questions are then used to make links to the upcoming topic of antibiotic resistance.
The next part of the lesson focuses on the differences between bactericidal and bacteriostatic antibiotics and the students will learn that penicillin is bactericidal as the weakening of the cell wall leads to lysis and death. Tetracycline is used as the example of a bacteriostatic antibiotic and students will discover that it is the prevention of the binding of tRNA that inhibits protein synthesis and that this reduction and prevention of growth and reproduction is synonymous with these antimicrobial agents. Students are challenged on their knowledge of translation and will also be given time for a class discussion to understand that these antibiotics work in tandem the body’s immune system to overcome the pathogen
The final part of the lesson explains why antibiotics are ineffective against viruses.
This lesson describes the movement of water from the root to the leaf and includes the transpiration stream and the cohesion-tension theory. The PowerPoint and accompanying resources have been designed to cover point (n) of topic 3 in AS unit 2 of the WJEC A-level Biology specification
This lesson has been written to follow on from a previous lesson, which finished with the description of the transport of the water and mineral ions from the endodermis to the xylem. Students are immediately challenged to use this knowledge to understand root pressure and the movement by mass flow down the pressure gradient. Moving forwards, time is taken to study the details of transpiration pull and the interaction between cohesion, tension and adhesion in capillary action is explained. Understanding is constantly checked through a range of tasks and prior knowledge checks are also written into the lesson to challenge the students to make links to previously covered topics such as the structure of the transport tissues. The final part of the lesson considers the journey of water through the leaf and ultimately out of the stomata in transpiration. A step by step guide using questions to discuss and answer as a class is used to support the students before the final task challenges them to summarise this movement out of the leaf.
This fully-resourced lesson describes the events of the cell cycle so that students can understand how the genetic material behaves in interphase, mitosis and cytokinesis. The detailed PowerPoint and accompanying resources have been designed to cover specification points 2.3 (i), (ii) and (iii) as detailed in the Edexcel A-level Biology B specification.
Depending upon the exam board taken at GCSE, the knowledge and understanding of mitosis and the cell cycle will differ considerably between students and there may be a number of misconceptions. This was considered at all points during the planning of the lesson and to address existing errors, key points are emphasised throughout. The cell cycle is introduced at the start of the lesson and the quantity of DNA inside the parent cell is described as diploid and as 2n. A quiz competition has been written into the lesson and this runs throughout, challenging the students to identify the quantity of DNA in the cell (in terms of n) at different points of the cycle. Moving forwards, the first real focus is interphase and the importance of DNA replication is explained so that students can initially recognise that there are pairs of identical sister chromatids and then can understand how they are separated later in the cycle. The main part of the lesson focuses on prophase, metaphase, anaphase and telophase and describes how the chromosomes behave in these stages. An exam style question will check on their knowledge of the organelles from 2.1 and this acts to remind them that centrioles are responsible for the production of the spindle apparatus, Students will understand how the cytoplasmic division that occurs in cytokinesis results in the production of genetically identical daughter cells. This leads into a series of understanding and application questions where students have to identify the various roles of mitosis in living organisms as well as tackling a Maths in a Biology context question. The lesson concludes with a final round of MITOSIS SNAP where they only shout out this word when a match is seen between the name of a phase, an event and a picture
This fully-resourced lesson distinguishes between active and passive, natural and artificial immunity and explains how vaccinations can be used to control disease. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 11.2 (d) of the CIE A-level Biology specification and there is also a description and discussion on the concept of herd immunity.
In topic 11.1, students were introduced to the primary and secondary immune responses so the start of this lesson uses an imaginary game of TOP TRUMPS to challenge them on the depth of their understanding. This will act to remind them that a larger concentration of antibodies is produced in a quicker time in the secondary response. The importance of antibodies and the production of memory cells for the development of immunity is emphasised and this will be continually referenced as the lesson progresses. The students will learn that this response of the body to a pathogen that has entered the body through natural processes is natural active immunity. Moving forwards, time is taken to look at vaccinations as an example of artificial active immunity. Another series of questions focusing on the MMR vaccine will challenge the students to explain how the deliberate exposure to antigenic material activates the immune response and leads to the retention of memory cells. A quick quiz competition is used to introduce the variety of forms that the antigenic material can take along with examples of diseases that are vaccinated against using these methods. The eradication of smallpox is used to describe the concept of herd immunity and the students are given time to consider the scientific questions and concerns that arise when the use of this pathway is a possible option for a government. The remainder of the lesson looks at the different forms of passive immunity and describes the drawbacks in terms of the need for a full response if a pathogen is re-encountered
This fully-resourced lesson describes the structure, different roles and modes of action of the B and T lymphocytes in the specific immune response. The detailed PowerPoint and accompanying resources have been designed to cover point 4.1.1 (f) as detailed in the OCR A-level Biology A specification and the structure of antibodies and the roles of memory cells is also briefly introduced so that students are prepared for an upcoming lesson on the secondary immune response (4.1.1 g)
Antigen presentation was introduced at the end of the previous lesson so the task at the start of this lesson challenges students to recognise the name of this process and then they have to spot the errors in the passage that describes the details of this event. This reminds them that contact between the APC and T lymphocytes is necessary to elicit a response which they will come to recognise as the cellular response. A series of quick quiz rounds reveals key terms in a memorable way and one that is introduced is helper T cells. Time is then taken to describe the importance of cell signalling for an effective response and students will learn how the release of chemicals by these cells activates other aspects of the response. The role of the killer T cells and their production of cytotoxins is also described before an exam-style question is used to check on their understanding at this point of the lesson. This leads into the section of the lesson that deals with the humoral response and students will understand how this involves the antibodies that are produced by the plasma cells that are the result of clonal selection and expansion. The T and B memory cells are also introduced so that students can understand how they are retained in the body even after the pathogen has been overcome and will play a critical role in the development of immunity. The remainder of the lesson focuses on the role of the antibodies and the attachment of phagocytes to opsonins
This fully-resourced lesson describes genetic biodiversity as the number of genes in a population and considers how it can be assessed. The engaging PowerPoint and accompanying differentiated resources have been primarily designed to cover point 4.2.1 (e) of the OCR A-level Biology A specification but also introduces inheritance and codominance so that students are prepared for these genetic topics when they are covered in module 6.1.2
In order to understand that 2 or more alleles can be found at a gene loci, students need to be confident with genetic terminology. Therefore the start of the lesson focuses on key terms including gene, locus, allele, recessive, genotype and phenotype. A number of these will have been met at GCSE, as well as during the earlier lessons in module 2.1.3 when considering meiosis, so a quick quiz competition is used to check on their recall of the meanings of these terms. The CFTR gene is then used as an example to demonstrate how 2 alleles results in 2 different phenotypes and therefore genetic diversity. Moving forwards, students will discover that more than 2 alleles can be found at a locus and they are challenged to work out genotypes and phenotypes for a loci with 3 alleles (shell colour in snails) and 4 alleles (coat colour in rabbits). Two calculations are provided to the students that can calculate the % of loci with more than one allele and the proportion of polymorphic gene loci. At this point, the students are introduced to codominance and again they are challenged to apply their understanding to a new situation by working out the number of phenotypes in the inheritance of blood groups. The lesson concludes with a brief consideration of the HLA gene loci, which is the most polymorphic loci in the human genome, and students are challenged to consider how this sheer number of alleles can affect the chances of tissue matches in organ transplantation
This lesson bundle contains 5 detailed lesson PowerPoints and their accompanying resources which have been designed to cover the content of module 5.1.4 (Hormonal communication) of the OCR A-level Biology A specification. They contain a wide variety of tasks which include exam-style questions with displayed mark schemes that challenge the students on their current understanding as well as their ability to make links to previously covered topics.
The following specification points are covered in this bundle:
Endocrine communication by hormones
The structure and functions of the adrenal glands
The histology of the pancreas
The regulation of blood glucose concentration by the release of insulin and glucagon
The control of insulin secretion
The difference between type I and II diabetes mellitus
The potential treatments for diabetes mellitus
If you would like to sample the quality of the lessons in this bundle, then download the endocrine communication lesson as this has been uploaded for free
