This engaging lesson describes the relationship between the structure, properties and functions of a phopholipid and cholesterol. The PowerPoint has been written as the second lesson in a series of two that cover specification points 2.1.2 (h), (i) & (j) of the OCR A-level Biology A course and there is a particular focus on their roles in membranes to link to module 2.1.5. In the previous lesson, the students met triglycerides and a quick quiz round called FAMILY AFFAIR is used at the start of the lesson to challenge the students on their knowledge of the structure of this macromolecule to identify the shared features in a phospholipid. This then allows the differences to be introduced, such as the presence of a phosphate group in place of the third fatty acid. Moving forwards, the students will learn that the two fatty acid tails are hydrophobic whilst the phosphate head is hydrophilic which leads into a key discussion point where the class has to consider how it is possible for the phospholipids to be arranged when both the inside and outside of a cell is an aqueous solution. The outcome of the discussion is the introduction of the bilayer which is critical for the lesson in module 2.1.5 on the fluid mosaic model. Students are briefly introduced to facilitated diffusion and reminded of active transport so they can recognise that proteins will be found in the membrane to allow for movement of large or polar molecules. The remainder of the lesson focuses on cholesterol, beginning with the structure. The hydrophobic nature of this molecule is then considered and discussed so that they can understand its role in the regulation of membrane fluidity. That just leaves one final quiz round which identifies vitamin D, testosterone and oestrogen as three substances that are formed from cholesterol

This fully-resourced lesson describes the regulatory mechanisms that control gene expression at a transcriptional level. The detailed PowerPoint and accompanying resources have been designed to cover the first part of point 6.1.1 (b) as detailed in the OCR A-level Biology A specification which states that the students knowledge should include the lac operon and examples of transcription factors in eukaryotes. . This is one of the more difficult concepts in this A-level course and therefore key points are reiterated throughout this lesson to increase the likelihood of student understanding and to support them when trying to make links to actual biological examples in living organisms. There is a clear connection to transcription and translation as covered in module 2.1.3, so the lesson begins by reminding students that in addition to the structural gene in a transcription unit, there is the promotor region where RNA polymerase binds. Students are introduced to the idea of transcription factors and will understand how these molecules can activate or repress transcription by enabling or preventing the binding of the enzyme. At this point, students are challenged on their current understanding with a series of questions about DELLA proteins so they can see how these molecules prevent the binding of RNA polymerase. Their understanding is then tested again with another example with oestrogen and the ER receptor. The final and main section of the lesson focuses on the lac operon and immediately an opportunity is taken to challenge their knowledge of biological molecules with a task where they have to spot the errors in a passage describing the formation and breakdown of this disaccharide. Students will be able to visualise the different structures that are found in this operon and time is taken to go through the individual functions. A step by step guide is used to walk students through the sequence of events that occur when lactose is absent and when it is present before they are challenged to apply their understanding to an exam question.

This lesson describes how communication occurs between cells by cell signalling. The PowerPoint and accompanying resource have been designed to cover point 5.1.1 (b) of the OCR A-level Biology A specification and focuses on the use of the nervous system for communication between the CNS and effectors and the release of hormones to bring about responses. As this is one of the first lessons to be delivered in module 5, this lesson has been specifically planned to prepare students for the upcoming topics of neuronal and hormonal communication. Students begin by learning that cell signalling governs the basic activities of cells and coordinates multiple cell actions. Moving forwards, the next part of the lesson focuses on the nervous system and students will learn that an electrical impulse will be conducted on a somatic or an autonomic motor neurone depending upon the type of muscle to be stimulated. This provides some introductory information for modules 5.1.3 and 5.1.5. The remainder of the lesson describes how the hormones that are secreted by the cells of endocrine glands allow communication with target cells and the different actions of peptide and steroid hormones is considered.

This lesson describes the gross structure of the human gas exchange system and the functions of the structural components like goblet cells. The PowerPoint and accompanying resources have been designed to cover points 9.1 (a & c) of the CIE A-level Biology specification and has been specifically planned to prepare students for an upcoming lesson where the gas exchange between the alveoli and the blood is described. The lesson is filled with a range of activities such as guided discussion periods, exam-style questions (with markschemes) and quiz competitions and these run alongside the slides containing the detailed A-level Biology content to cover the following features: The incomplete rings of cartilage, ciliated pseudostratified columnar epithelium and goblet cells in the trachea The narrowing airways of the primary, secondary and tertiary bronchi The elastic fibres and smooth muscle in the terminal and respiratory bronchioles The pleural cavity and fluid of the lungs When describing the production of mucus by the goblet cells in the trachea, time is taken to consider cystic fibrosis and the inheritance of this autosomal recessive disorder. Students will be supported in working out genotypes from a pedigree tree to prepare them for topic 16 (Inherited change)

This lesson describes the in situ and ex situ methods of maintaining biodiversity, and discusses the advantages and disadvantages associated with both. The engaging PowerPoint and accompanying worksheets have been primarily designed to cover point 4.2.1 (h) of the OCR A-level Biology A specification but the lesson has been carefully planned to enable links to be made to some related topics which are found later in the course such as classification, evolution through natural selection and the Founder effect. Hours of research has gone into the planning of this lesson to source interesting examples that increase the relevance of the biological content concerning in situ conservation, and these include the Lizard National Nature Reserve in Cornwall, the Lake Télé Community reserve in the Republic of Congo and the marine conservation zone in the waters surrounding Tristan da Cunha. Students will learn how this form of active management conserves habitats and species in their natural environment, with the aim of minimising human impact whilst maintaining biodiversity. The main issues surrounding this method are discussed, including the fact that the impact of this conservation may not be significant if the population has lost much of its genetic diversity and that despite the management, the conditions that caused the species to become endangered may still be present. A number of quick quiz competitions are interspersed throughout the lesson to introduce key terms and values in a fun and memorable way and one of these challenges them to use their knowledge of famous scientists to reveal the surname, Fossey. Dian Fossey was an American conservationist and her years of study of the mountain gorillas is briefly discussed along with the issue that wildlife reserves can draw poachers and tourists to the area, potentially disturbing the natural habitat. To enrich their understanding of ex situ conservation, the better known examples of ZSL London zoo, Kew Gardens and the Millennium Seed Bank Project in Wakehurst are used. Students will understand how conserving animal species outside of their natural habitat enables human intervention that ensures the animals are fed and given medical assistance when needed as well as reproductive assistance to increase the likelihood of the successful breeding of endangered species. As with the in situ method, the disadvantages are also discussed and there is a focus on the susceptibility of captive populations to diseases as a result of their limited genetic diversity. The final part of the lesson considers how seed banks can be used to ensure that plant species avoid extinction and how the plants can be bred asexually to increase plant populations quickly. Due to the extensiveness of this lesson, it is estimated that it will take in excess of 2/3 hours of allocated A-level teaching time to cover the tasks and content that is included in the lesson.

This lesson has been designed to cover the content as detailed in points 2.15, 2.16 and 2.17 (The eye as a sensory receptor and the correction of eye defects) of the Edexcel GCSE Biology specification. Consisting of a detailed and engaging PowerPoint (54 slides) and accompanying worksheets, the range of activities will motivate the students whilst ensuring that the content is covered in detail. Students will learn how the structures of the eye enable it to function as a sensory receptor, with a particular focus on the role of the cornea, lens, iris and the rod and cone cells in the retina. In addition, students will understand how eye defects such as short-sightedness and cataracts can cause problems for vision and can be corrected. Progress checks are included throughout the lesson so that students can assess their understanding of the content and any misconceptions can be addressed whilst quiz competitions are used to introduce new terms in a fun and memorable way. This lesson has been written for GCSE-aged students who are studying the Edexcel GCSE Biology specification but can be used with younger students who have a real interest in this sensory receptor as well as older students who need to know the key details for their A level course.

This lesson has been written to cover the part of specification point 6.4.3 of the AQA A-level Biology specification which states that students should be able to describe how water and glucose are reabsorbed in the proximal convoluted tubule. It has specifically been designed to build on the knowledge gained in the previous lessons on the structure of the nephron and ultrafiltration. The lesson begins by challenging the students to recall the substances that are found in the glomerular filtrate so that each of them can be considered over the course of the rest of the lesson. Moving forwards, the first of the numerous discussion points which are included in the lesson is used to get students to predict the component of the filtrate which won’t be found in the urine when they are presented with pie charts from each of these situations. Upon learning that glucose is 100% reabsorbed, along with most of the ions and some of the water, the rest of the lesson focuses on describing the relationship between the structure of the PCT and the function of selective reabsorption. Again, this section begins by encouraging the students to discuss and to predict which structures they would expect to find in a section of the kidney if the function is to reabsorb. They are given the chance to see the structure (as shown in the cover image) before each feature is broken down to explain its importance. Time is taken to look at the role of the cotransporter proteins to explain how this allows glucose, along with sodium ions, to be reabsorbed from the lumen of the PCT into the epithelial cells. The final part of the lesson focuses on urea and how the concentration of this substance increases along the tubule as a result of the reabsorption of some of the water. This lesson has been designed for students studying on the AQA-A level Biology course and ties in nicely with the other lessons from 6.4.3 as well as the other uploaded lessons from topic 6

This lesson looks at the use of the polymerase chain reaction (PCR) as an in vitro method to amplify DNA fragments as part of the recombinant DNA technology process. The clear PowerPoint has been designed to cover the second part of point 8.4.1 of the AQA A-level Biology specification. A quick quiz competition is used to introduce the PCR abbreviation before students are encouraged to discuss the identity of the enzyme involved and to recall the action of this enzyme. Students will learn that this reaction involves cyclical heating and cooling to a range of temperatures so the next part of this lesson looks at these particular temperatures so the important parts of each of the steps can be understood. Time is taken to examine the key points in detail, such as the specific DNA polymerase that is used and how it is not denatured at the high temperature as well as the involvement of the primers.

This fully-resourced lesson describes the behaviour of chromosomes during interphase, mitosis and cytokinesis in the cell cycle. The detailed PowerPoint and accompanying resources have been designed to cover the first half of point 2.2 as detailed in the AQA A-level Biology specification whereas uncontrolled cell division and cancer and binary fission are covered in upcoming lessons. Depending upon the exam board taken at GCSE, the knowledge and understanding of mitosis and the cell cycle will differ considerably between students and there may be a number of misconceptions. This was considered at all points during the planning of the lesson and to address existing errors, key points are emphasised throughout. The cell cycle is introduced at the start of the lesson and the quantity of DNA inside the parent cell is described as diploid and as 2n. A quiz competition has been written into the lesson and this runs throughout, challenging the students to identify the quantity of DNA in the cell (in terms of n) at different points of the cycle. Moving forwards, the first real focus is interphase and the importance of DNA replication is explained so that students can initially recognise that there are pairs of identical sister chromatids and then can understand how they are separated later in the cycle. The main part of the lesson focuses on prophase, metaphase, anaphase and telophase and describes how the chromosomes behave in these stages. Centrioles were not covered in the topic 2.1 lessons on cell structures so a quick task will introduce them to these organelles who are responsible for the production of the spindle apparatus, Students will understand how the cytoplasmic division that occurs in cytokinesis results in the production of genetically identical daughter cells. This leads into a series of understanding and application questions where students have to identify the various roles of mitosis in living organisms as well as tackling a Maths in a Biology context question. The lesson concludes with a final round of MITOSIS SNAP where they only shout out this word when a match is seen between the name of a phase, an event and a picture.

This fully-resourced lesson distinguishes between active and passive, natural and artificial immunity and explains how vaccinations can be used to control disease. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 11.2 (d) of the CIE A-level Biology specification and there is also a description and discussion on the concept of herd immunity. In topic 11.1, students were introduced to the primary and secondary immune responses so the start of this lesson uses an imaginary game of TOP TRUMPS to challenge them on the depth of their understanding. This will act to remind them that a larger concentration of antibodies is produced in a quicker time in the secondary response. The importance of antibodies and the production of memory cells for the development of immunity is emphasised and this will be continually referenced as the lesson progresses. The students will learn that this response of the body to a pathogen that has entered the body through natural processes is natural active immunity. Moving forwards, time is taken to look at vaccinations as an example of artificial active immunity. Another series of questions focusing on the MMR vaccine will challenge the students to explain how the deliberate exposure to antigenic material activates the immune response and leads to the retention of memory cells. A quick quiz competition is used to introduce the variety of forms that the antigenic material can take along with examples of diseases that are vaccinated against using these methods. The eradication of smallpox is used to describe the concept of herd immunity and the students are given time to consider the scientific questions and concerns that arise when the use of this pathway is a possible option for a government. The remainder of the lesson looks at the different forms of passive immunity and describes the drawbacks in terms of the need for a full response if a pathogen is re-encountered

This resource contains an engaging and detailed lesson PowerPoint and accompanying worksheets which cover the content of both the Core and Supplement sections of topic 14.2 (Sense organs) as detailed in the CIE IGCSE Biology specification. Understanding checks are included at regular points throughout the lesson to allow the students to self-assess their progress and quiz competitions like SAY WHAT YOU SEE and LOOK into these WORDS introduce key terms in a fun and memorable way. The following content is covered across this resource: The function of the cornea, retina, lens, optic nerve and iris Identifying these structures and the pupil, fovea and blind spot on a diagram The roles of the rods and cones in the retina and their distribution Explain the pupil reflex in terms of the antagonistic action of the muscles in the iris Accommodation to view near and distant objects Sense organs and the stimuli to which they respond This lesson has been designed for GCSE-aged students who are studying the CIE IGCSE Biology course but is suitable for both younger and older students who are studying this organ

A fully resourced revision lesson that uses a combination of exam questions, understanding checks, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within modules B1, B2 and B3 of the OCR Gateway A GCSE Biology specification as will be covered in Biology paper 1 The topics that are tested within the lesson include: Cell structures What happens in cells Respiration Photosynthesis Supplying the cell The challenge of size The nervous system The endocrine system Maintaining internal environments Students will be engaged through the numerous quiz rounds whilst crucially being able to recognise those areas which require further attention

This engaging lesson presentation (58 slides) and associated worksheets uses exam questions with displayed mark schemes, quick tasks and quiz competitions to enable students to assess their understanding of the topics found within module B4 of the OCR Gateway A GCSE Biology specification. The topics which are specifically tested within the lesson include: Ecosystems, Competition and interdependence, Pyramids of biomass, Efficiency of biomass transfer, The carbon cycle and Decomposers Students will enjoy the competitions such as "Number CRAZY" and "Take the HOTSEAT" whilst crucially being able to recognise those areas which need their further attention

An engaging lesson presentation (64 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B1 (Cell Biology) of the AQA GCSE Combined Science specification (specification point 4.1). The topics that are tested within the lesson include: Eukaryotes and prokaryotes Animal and plant cells Microscopy Chromosomes The cell cycle including mitosis Stem cells Diffusion Osmosis Active transport Students will be engaged through the numerous activities including quiz rounds like “SPOT the CELL” and “Take the Hotseat” whilst crucially being able to recognise those areas which need further attention