This fully-resourced lesson describes the roles of the hypothalamus and the pituitary gland in the control of mammalian plasma concentration. The engaging PowerPoint and accompanying resources have been designed to cover point 7.21 of the Edexcel International A-level Biology specification The principles of homeostasis and negative feedback were covered in an earlier lesson in topic 7, so this lesson acts to build on that knowledge and challenges them to apply their knowledge. A wide range of activities have been included in the lesson to maintain motivation and engagement whilst the understanding and prior knowledge checks will allow the students to assess their progress as well as challenge themselves to make links to other Biology topics. The lesson begins with a discussion about how the percentage of water in urine can and will change depending on the blood water potential. Students will quickly be introduced to osmoregulation and they will learn that the osmoreceptors and the osmoregulatory centre are found in the hypothalamus. A considerable amount of time is taken to study the cell signalling between the hypothalamus and the posterior pituitary gland by looking at the specialised neurones (neurosecretory cells). Links are made to the topics of neurones, nerve impulses and synapses and the students are challenged to recall the cell body, axon and vesicles. The main section of the lesson forms a detailed description of the body’s detection and response to a low blood water potential. The students are guided through this section as they are given 2 or 3 options for each stage and they have to use their knowledge to select the correct statement. The final task asks the students to write a detailed description for the opposite stimulus and this task is differentiated so those who need extra assistance can still access the work.

This lesson describes the role of myelination in saltatory conduction. The PowerPoint and accompanying worksheet have been designed to cover point 8.5 of the Edexcel International A-level Biology specification and includes constant references to the earlier lessons on the structure of neurones and the conduction of an action potential along an axon. A wide range of activities have been written into this resource to maintain the motivation of the students whilst ensuring that the detail is covered in depth. Interspersed with the activities are understanding checks and prior knowledge checks to allow the students to not only assess their understanding of the current topic but also challenge themselves to make links to earlier topics such as the movement of ions across membranes and biological molecules. Time at the end of the lesson is also given to future knowledge such as the involvement of autonomic motor neurones in the stimulation of involuntary muscles. Over the course of the lesson, students consider the structure of the myelin sheath and specifically how the insulation is not complete all the way along which leaves gaps known as the nodes of Ranvier which allow the entry and exit of ions. Saltatory conduction tends to be poorly explained by students so time is taken to look at the way that the action potential jumps between the nodes and this is explained further by reference to local currents. The rest of the lesson focuses on the other two factors which are axon diameter and temperature and students are challenged to discover these two by focusing on the vampire squid.

This lesson describes the role of the posterior pituitary gland and ADH in the homeostatic balance of blood water potential. The PowerPoint and accompanying resources have been designed to cover specification points (f & g) in topic 7 of A2 unit 3 of the WJEC A-level Biology specification. Students learnt about the principles of homeostasis and negative feedback in an earlier lesson in this topic, so this lesson acts to build on that knowledge and challenges them to apply their knowledge. A wide range of activities have been included in the lesson to maintain motivation and engagement whilst the understanding and prior knowledge checks will allow the students to assess their progress as well as challenge themselves to make links to other Biology topics. The lesson begins with a discussion about how the percentage of water in urine can and will change depending on the blood water potential. Students will quickly be introduced to osmoregulation and they will learn that the osmoreceptors and the osmoregulatory centre are found in the hypothalamus. A considerable amount of time is taken to study the cell signalling between the hypothalamus and the posterior pituitary gland by looking at the specialised neurones (neurosecretory cells). Links are made to the topics of neurones, nerve impulses and synapses and the students are challenged to recall the cell body, axon and vesicles. The main section of the lesson forms a detailed description of the body’s detection and response to a low blood water potential. The students are guided through this section as they are given 2 or 3 options for each stage and they have to use their knowledge to select the correct statement. The final task asks the students to write a detailed description for the opposite stimulus

This lesson describes the key events of the eukaryotic cell cycle and specifically focuses on those that occur in interphase. The PowerPoint and accompanying resources have been designed to cover point (a) in topic 6 of AS unit 1 of the WJEC A-level Biology specification and also introduces the stages of mitosis and cytokinesis to prepare students for the upcoming lesson on the significance of this type of cell division. The students were introduced to the cell cycle at GCSE so this lesson has been planned to build on that knowledge and to emphasise that the M phase which includes mitosis (nuclear division) only occupies a small part of the cycle. The students will learn that interphase is the main stage and that this is split into three phases, G1, S and G2. A range of tasks which include exam-style questions, guided discussion points and quick quiz competitions are used to introduce key terms and values and to describe the main processes that occur in a very specific order. Extra time is taken to ensure that key terminology is included and understood, such as sister chromatid and centromere, and this focus helps to show how it is possible for genetically identical daughter cells to be formed at the end of the cycle.

This lesson describes how the antagonistic action of the radial and circular muscles of the iris causes the pupil to dilate or contract. The PowerPoint has been designed to cover point 8.2 (ii) of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification. The students may have encountered this concept at GCSE, so this lesson has been written to build on that knowledge and includes key A-level details such as the innervation of the smooth muscles by divisions of the autonomic nervous system. Students will learn how the contraction of the radial muscles pulls the iris radially and enlarges the pupil, allowing more light to enter when an individual is in a room with dim light and that this contraction is the result of the conduction of an electrical impulse along a sympathetic motor neurone.

This concise lesson acts as an introduction to topic 5.3, Energy and Ecosystems, and describes how plant biomass is formed, measured and estimated. The engaging PowerPoint is the 1st in a series of 3 lessons which have been designed to cover the detailed content of topic 5.3 of the AQA A-level Biology specification. A quiz round called REVERSE Biology Bingo runs throughout the lesson and challenges students to recognise the following key terms from descriptions called out by the bingo caller: community ecosystem abiotic factor photosynthesis respiratory substrate biomass calorimetry The ultimate aim of this quiz format is to support the students to understand that any sugars produced by photosynthesis that are not used as respiratory substrates are used to form biological molecules that form the biomass of a plant and that this can be estimated using calorimetry. Due to the clear link to photosynthesis, a series of prior knowledge checks are used to challenge the students on their knowledge of this cellular reaction but as this is the first lesson in the topic, the final section of the lesson looks forwards and introduces the chemical energy store in the plant biomass as NPP and students will also meet GPP and R so they are partially prepared for the next lesson.

This lesson describes how iPS cells are formed from fibroblasts and discusses why this method is less controversial than the use of embryonic stem cells. The PowerPoint and accompanying resources are part of the 2nd lesson in a series of 2 lessons which covers the content of point 7.3 (stem cells) of the Edexcel A-level biology B specification. The lesson begins with a SPOT THE ERRORS task, where students have to use their knowledge of pluripotent cells from the previous lesson to identify the 3 errors and make corrections. The aim of this task is to remind them that pluripotent cells are found in embryos and can divide in unlimited numbers before finally becoming fully differentiated somatic cells. Moving forwards, the students are introduced to fibroblasts as examples of these somatic cells and the opportunity is taken to challenge their knowledge of collagen as this is a substance produced by these cells. The answers are embedded into the PowerPoint to allow the students to assess their recall of this topic 1 content. A quick quiz is used to introduce the acronym iPS and students will learn that fibroblasts can be reprogrammed to form induced pluripotent cells using specific transcription factors. The remainder of the lesson challenges them to answer questions about the use of iPS cells in regenerative medicine after reading a passage about an example. This allows them to recognise that deriving these cells from adult tissues as opposed to embryonic stem cells raises less problems and the transplant into the same person reduces the risk of rejection.

This lesson describes the biological meaning of species, populations, gene pool and allele frequency and explains how these terms are linked. The PowerPoint and accompanying resources are part of the 1st lesson in a series of 2 lessons that cover the detail of specification point 7.2 (Populations) of the AQA A-level biology. The two living species of the African elephant, the forest and bush elephant, are used as examples to demonstrate the meaning of species and to show how they exist as one or more populations. A quick quiz introduces the term gene pool in an engaging way and then the allele frequency of three versions of the GBA gene demonstrates how these frequencies can change in small populations. In doing so, students are briefly introduced to genetic drift which they will encounter in an upcoming topic. The students are challenged throughout the lesson with understanding checks and prior knowledge checks as well as exam-based questions where they have to comment on the validity of a scientist’s conclusion. The other lesson in topic 7.2 is the Hardy-Weinberg principle.

This fully-resourced lesson looks at the blood circulation in a mammal and considers how the pulmonary circulation differs from the systemic circulation. The engaging PowerPoint and accompanying resources have been designed to cover the third part of point 3.4.1 of the AQA A-level Biology specification The lesson begins with a focus on the double circulatory system and checks that students are clear in the understanding that the blood passes through the heart twice per cycle of the body. Beginning with the pulmonary circulation, students will recall that the pulmonary artery carries the blood from the right ventricle to the lungs. An opportunity is taken at this point to check on their knowledge of inhalation and the respiratory system as well as the gas exchange between the alveoli and the capillary bed. A quick quiz is used to introduce arterioles and students will learn that these blood vessels play a crucial role in the changes in blood pressure that prevent the capillaries from damage. When looking at the systemic circulation, time is taken to look at the coronary arteries and renal artery as students have to be aware of these vessels in addition to the ones associated with the heart. In the final part of the lesson, students are challenged to explain how the structure of the heart generates a higher pressure in the systemic circulation and then to explain why the differing pressures are necessary. This lesson has been written to tie in with the other uploaded lessons from topic 3.4.1 (mass transport in animals)

A detailed lesson presentation (37 slides) and associated worksheets that looks at the different pieces of evidence that scientists use to support evolution and discusses how these support the theory. The lesson begins by challenging students to decide which piece of evidence is the key piece in supporting evolution (fossils). Students will then have to arrange a number of statements to describe how a fossil is formed. Students are introduced to the fossil record and questions are used to check that they understand where the oldest fossils would be found. Moving forwards, students are given three pieces of evidence that would be observed in the fossil record and they are challenged to explain how each of these supports the theory of evolution. Quick competitions are then used to get the students to see some extinct organisms in the Dodo and Woolly Mammoth and again they are questioned on how extinct animals support the theory of evolution. Further evidence in rapid changes in species and molecular comparison is discussed. There are regular progress checks throughout the lesson so that students can assess their understanding and there is a set homework included.

A detailed and engaging lesson presentation (43 slides) and accompanying worksheets that introduces students to the disease, Diabetes (mellitus), and focusses on the similarities and differences between types I and II. The lesson begins by challenging the students mathematically to get the answers 1 and 2 and then to see whether they can link these numbers to a disease. A variety of tasks, which includes competitions and progress checks, are used to get the students to recognise the differences and state which of the types they belong to. This lesson has been designed for GCSE students and can be used with higher level students. However, a lesson more appropriate for A-level Biology students is named “Diabetes Mellitus Type I and II” and is available in my resources

This lesson revisits the topic of random and systematic errors and also challenges students on other scientific skills such as identifying variables. Students tend to find this topic confusing, so the PowerPoint and accompanying resources have been designed to support them to identify whether an error is random or systematic and then to understand what to do next. The lesson guides the students through a series of real life examples and shows them how to spot each type of error. There is a considerable mathematical element to this lesson, including the calculation of means or missing values in a table. The lesson concludes with a series of exam-style questions where the students have to apply their understanding of identifying errors, variables and calculating means.

This revision lesson challenges students to explain the results of an osmosis investigation and to calculate accelerations using 2 equations. The PowerPoint and accompanying resources have been designed to check on the understanding of these two topics as detailed in the AQA GCSE biology, physics and combined specifications. The lesson contains a range of tasks including worked examples, exam questions and quizzes which will remind students that water molecules move across partially permeable membranes by osmosis and how changes in the mass of a potato can be used to compare water concentrations in the potato and solution. Students will also recall that acceleration can be calculated from velocity-time graphs using change in velocity/time as well as through the use of F=ma.

A concise lesson presentation (20 slides) and associated worksheet that guides students through phylogenetic trees and helps them to be able to interpret these diagrams. The lesson begins by stating three key points about the trees which will form the basis of their understanding. Moving forwards, a series of questions with explained answers are used to show how common ancestors in the past can be used to work out which present day organisms are the most closely related. Students are given lots of opportunities to assess their understanding and check that they can explain. This lesson has been written for GCSE but could be used as a recap for those students studying at A-level

This lesson has been designed to cover the content of the 1st part of specification point 6.1.2 of the AQA A-level Biology specification which states that students should know the basic structure of a Pacinian corpuscle and be able to use its function as a representation of sensory receptors. By the end of the lesson students will understand that sensory receptors respond to specific stimuli and how a generator potential is established. The lesson begins by using a quiz to get the students to recognise the range of stimuli which can be detected by receptors. This leads into a task where the students have to form 4 sentences to detail the stimuli which are detected by certain receptors and the energy conversion that happen as a result. Students will be introduced to the idea of a transducer and learn that receptors always convert to electrical energy which is the generator potential. The remainder of the lesson focuses on the Pacinian corpuscle and how this responds to pressure on the skin. The involvement of sodium and potassium ions is introduced so discussions on how the membrane potential changes from resting potential in the establishment of a generator potential are encouraged. This lesson has been written for students studying on the AQA A-level Biology course and ties in nicely with other uploaded lessons which cover the content of topic 6

This is a fast-paced lesson which goes through the main steps of selective breeding and looks at the potential risks of this process. The lesson begins by looking at the characteristics of a number of organisms that would be selected. Time is taken to ensure that students understand that selective breeding is not a new thing and has been going on for a very long time and therefore some of the problems associated with this are now being experienced. The actual process is reduced down into 5 steps which can be recalled and applied to questions. The remainder of the lesson looks at the potential issues with selective breeding. The reduction in the nose size of pugs is explored as an example of the health problems which bred animals may face. This lesson has been written for GCSE students.

This lesson describes how to prepare and examine microscope slides and the use of staining in light microscopy. The PowerPoint and accompanying resources have been designed to cover points 2.1.1 (b & c) of the OCR A-level Biology A specification and describe how the eyepiece graticule and stage micrometer are used to measure the size of an object with a light microscope and the use of eosin and methylene blue. The main task of this lesson involves a step by step guide which walks students through the methodology and the use of the scale on the stage micrometer to identify the size of the divisions of the eyepiece graticule and this will need them to convert between units. Moving forwards, the students are challenged to apply this method to a series of exam-style questions and the mark scheme is displayed on the PowerPoint so that they can assess their understanding. In the last lesson, they were briefly introduced to the idea that some specimens need to be stained as light passes completely through transparent samples and the remainder of the lesson builds on this knowledge. Students will learn that cell populations, structures within cells and biological tissues can be distinguished using stains and a series of questions will challenge them to make links to biological molecules, organelles and infections. Links are also made to the upcoming topic of epithelial tissue in the respiratory system. This lesson has been specifically written to tie in with the previous lesson on light and electron microscopes and 2 rounds of the sub-module quiz competition are found in this lesson.

This lesson describes how communication occurs between cells by cell signalling. The PowerPoint and accompanying resource have been designed to cover point 5.1.1 (b) of the OCR A-level Biology A specification and focuses on the use of the nervous system for communication between the CNS and effectors and the release of hormones to bring about responses. As this is one of the first lessons to be delivered in module 5, this lesson has been specifically planned to prepare students for the upcoming topics of neuronal and hormonal communication. Students begin by learning that cell signalling governs the basic activities of cells and coordinates multiple cell actions. Moving forwards, the next part of the lesson focuses on the nervous system and students will learn that an electrical impulse will be conducted on a somatic or an autonomic motor neurone depending upon the type of muscle to be stimulated. This provides some introductory information for modules 5.1.3 and 5.1.5. The remainder of the lesson describes how the hormones that are secreted by the cells of endocrine glands allow communication with target cells and the different actions of peptide and steroid hormones is considered.

A whole lesson on the topic of active transport which includes a concise lesson presentation (20 slides) and a set of questions that are used to check on the students’ understanding. This lesson is designed for GCSE students (14 - 16 year olds in the UK) but could be used with A-level students who are covering the topic of movement across cell membranes. The main focus of the lesson is to get students to understand that this is an active process which moves substances against the concentration gradient and therefore needs energy for this process. The final part of the lesson looks at the different types of questions that can accompany this topic and a step-by-step guide is used to answer a difficult longer answer question as a class.

Amino acids are the monomers of polypeptides and this lesson describes their structure and makes links to related topics such as genes and dipeptides. The engaging PowerPoint has been designed to cover the first part of point 1.4.1 of the AQA A-level Biology specification and provides a clear introduction to the following lesson on the formation of dipeptides and polypeptides. The lesson begins with a prior knowledge check, where the students have to use the 1st letters of 4 answers to uncover a key term. This 4-letter key term is gene and the lesson begins with this word because it is important for students to understand that these sequences of bases on DNA determine the specific sequence of amino acids in a polypeptide. Moving forwards, students are given discussion time to work out that there are 64 different DNA triplets and will learn that these encode for the 20 amino acids that are common to all organisms. The main task of the lesson is an observational one, where students are given time to study the displayed formula of 4 amino acids. They are not allowed to draw anything during this time but will be challenged with 3 multiple choice questions at the end. This task has been designed to allow the students to visualise how the 20 amino acids share common features in an amine and an acid group. A quick quiz round introduces the R group and time is taken to explain how the structure of this side chain is the only structural difference, before cysteine is considered in greater detail due to the presence of sulfur atoms. Students are briefly introduced to disulfide bridges so they will recognise how particular bonds form between the R groups in the tertiary structure which is covered in the next lesson. The lesson concludes with one more quiz round called LINK TO THE FUTURE where the students will see the roles played by amino acids in the later part of the course such as translation and mineral ions.