This detailed, concise lesson describes and explains how the electron transport chain and chemiosmosis are involved in the synthesis of ATP by oxidative phosphorylation. The PowerPoint has been designed to cover point 7.6 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification and also looks at the role of the enzyme, ATP synthase. The lesson begins with a discussion about the starting point of the reaction. In the previous stages, the starting molecule was the final product of the last stage but in this stage, it is the reduced coenzymes which release their hydrogen atoms. Moving forwards, the process of oxidative phosphorylation is covered in 7 steps and at each point, key facts are discussed and explored in detail to enable a deep understanding to be developed. Students will see how the proton gradient is created and that the flow of protons down the channel associated with ATP synthase results in a conformational change and the addition of phosphate groups to ADP. Understanding checks are included throughout the lesson to enable the students to assess their progress. This lesson has been written to tie in with the other uploaded lessons on glycolysis, the Link reaction and Krebs cycle and anaerobic respiration.

This fully-resourced lesson looks at the details of glycolysis as the first stage of aerobic and anaerobic respiration and explains how the sequence of reactions results in glucose being converted to pyruvate. The engaging PowerPoint and accompanying differentiated resources have been designed to cover the second part of point 5.2 of the AQA A-level Biology specification which states that students should know glycolysis as the phosphorylation of glucose and the production and subsequent oxidation of triose phosphate. The lesson begins with the introduction of the name of the stage and then explains how the phosphorylation of the hexoses and the production of the ATP, coenzymes and pyruvate are the stages that need to be known for this specification. Time is taken to go through each of these stages and key points such as the use of ATP in phosphorylation are explained so that students can understand how this affects the net yield. A quick quiz competition is used to introduce NAD and the students will learn that the reduction of this coenzyme, which is followed by the transport of the protons and electrons to the cristae for the electron transport chain is critical for the overall production of ATP. Understanding checks, in a range of forms, are included throughout the lesson so that students can assess their progress and any misconceptions are immediately addressed. This lesson has been written to tie in with the other uploaded lessons on anaerobic respiration and the different stages of aerobic respiration (the Link reaction, Krebs cycle and oxidative phosphorylation)

This engaging and fully-resourced lesson looks at the effects of stabilising, directional and disruptive selection as the three main types of selection. The PowerPoint and accompanying resources have been designed to cover point 17.2 (b) of the CIE International A-level Biology specification which states that students should be able to identify each type of selection by its effect on different phenotypes. The lesson begins with an introduction to the mark, release, recapture method to calculate numbers of rabbits with different coloured fur in a particular habitat. This method is covered later in topic 18 so this section of the lesson is designed purely to generate changes in numbers of the organisms. Sketch graphs are then constructed to show the changes in the population size in this example. A quick quiz competition is used to engage the students whilst introducing the names of the three main types of selection before a class discussion point encourages the students to recognise which specific type of selection is represented by the rabbits. Key terminology including intermediate and extreme phenotypes and selection pressure are used to emphasise their importance during explanations. A change in the environment of the habitat and a change in the numbers of the rabbits introduces directional selection before students will be given time to discuss and to predict the shape of the sketch graph for disruptive selection. Students are challenged to apply their knowledge in the final task of the lesson by choosing the correct type of selection when presented with details of a population and answer related questions.

This detailed and fully-resourced lesson describes and explains the pressure changes in the heart and arteries and the role of the valves movements in the cardiac cycle. The PowerPoint and accompanying resources have been designed to cover point 3.1.2 (f) of the OCR A-level Biology A specification and also covers the use of the equation stroke volume x heart rate to calculate cardiac output The start of the lesson introduces the cardiac cycle as well as the key term systole, so that students can immediately recognise that the three stages of the cycle are atrial and ventricular systole followed by diastole. Students are challenged on their prior knowledge of the structure of the heart as they have to name and state the function of an atrioventricular and semi-lunar valve from an internal diagram. This leads into the key point that pressure changes in the chambers and the major arteries results in the opening and closing of these sets of valves. Students are given a description of the pressure change that results in the opening of the AV valves and shown where this would be found on the graph detailing the pressure changes of the cardiac cycle. They then have to use this as a guide to write descriptions for the closing of the AV valve and the opening and closing of the semi-lunar valves and to locate these on the graph. By providing the students with this graph, the next part of the lesson can focus on explaining how these changes come about. Students have to use their current and prior knowledge of the chambers and blood vessels to write 4 descriptions that cover the cardiac cycle. Moving forwards, the students are introduced to the stroke volume and meet normative values for this and for resting heart rate. This will lead into the calculation for cardiac output and a series of questions are used to test their ability to apply this equation as well as to calculate the percentage change which is a commonly assessed mathematical skill. This lesson has been written to tie in with the other uploaded lessons on the topics detailed in module 3.1.2 (Transport in animals)

This lesson describes the active loading of sucrose at the source and movement by mass flow to the sink down the hydrostatic pressure gradient. Both the detailed PowerPoint and accompanying resources have been designed to cover points 7.2 (g, h & i) as detailed in the CIE International A-level Biology specification. The lesson begins by challenging the students to recognise the key term translocation when it is partially revealed and then the rest of the lesson focuses on getting them to understand how this process involves the mass flow of assimilates down the hydrostatic pressure gradient from the source to the sink. It has been written to tie in with 7.1 (d) where the structure of the phloem tissue was initially introduced and the students are continually challenged on their prior knowledge. A step-by-step guide is used to describe how sucrose is loaded into the phloem at the source by the companion cells. Time is taken to discuss key details such as the proton pumping to create the proton gradient and the subsequent movement back into the cells by facilitated diffusion using co-transporter proteins. Students will learn that the hydrostatic pressure at the source is high, due to the presence of the water and sucrose as cell sap, and that this difference when compared to the lower pressure at the sink leads to the movement along the phloem. A number of quick quiz rounds are included in the lesson to maintain engagement and to introduce key terms and the lesson concludes with a game of SOURCE or SINK as students have to identify whether a plant structure is one or the other (or both)

This fully-resourced lesson describes the process of DNA replication and explains how this ensures genetic continuity between generations. Both the detailed PowerPoint and accompanying resources have been designed to cover point 1.5.2 of the AQA A-level Biology specification and also explains why it is known as semi-conservative. The main focus of this lesson is the roles of DNA helicase in the breaking the hydrogen bonds between nucleotide bases and DNA polymerase in forming the growing nucleotide strands. Students are also introduced to DNA ligase to enable them to understand how this enzyme functions to join the nucleic acid fragments. Time is taken to explain key details, such as the assembly of strands in the 5’-to-3’ direction, so that the continuous manner in which the leading strand is synthesised can be compared against that of the lagging strand. The students are constantly challenged to make links to previous topics such as DNA structure and hydrolysis reactions through a range of exam questions and answers are displayed so that any misconceptions are quickly addressed. The main task of the lesson asks the students to use the information provided in the lesson to order the sequence of events in DNA replication before discussing how the presence of a conserved strand and a newly built strand in each new DNA molecule shows that it is semi-conservative.

An engaging lesson presentation (36 slides) that looks at the three types of muscle that are found in the body and then focusses on the structure and features of the involuntary muscles, cardiac and smooth. The lesson begins by challenging the students to recall the names of the different types and then gets them to recognise that cardiac and smooth are able to contract without conscious thought. Moving forwards, time is taken to look at the details of these muscles and key terminology such as intercalated discs and gap junctions are introduced so that students can understand how they perform their different functions. There are regular progress checks throughout the lesson so that students can assess their understanding. This lesson has been designed for A-level Biology lessons.

An engaging lesson presentation (81 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within Topic 7 (Animal coordination and homeostasis) of the EDEXCEL GCSE Biology specification The topics that are tested within the lesson include: The endocrine system Thyroxine The menstrual cycle Hormonal and barrier methods of contraception Homeostasis Thermoregulation Osmoregulation Control of blood glucose concentration DIabetes Students will be engaged through the numerous activities including quiz rounds like “Have they got the right BALANCE?" and the “B7 ABBREVIATIONS” whilst crucially being able to recognise those areas which need further attention

An engaging lesson presentation (57 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within Topic 9 (Ecosystems and material cycles) of the EDEXCEL GCSE Combined Science specification The topics that are tested within the lesson include: Levels of organisation Communities Interdependence in a community Determining the number of organisms in a given area Recycling materials Deforestation Global warming Students will be engaged through the numerous activities including quiz rounds like “Number CRAZY" whilst crucially being able to recognise those areas which need further attention

This is a fully-resourced lesson which looks at how IVF is used a treatment for infertility and considers the arguments for and against this process. The lesson includes an engaging, informative and discussion provoking lesson presentation and a pair of differentiated worksheets which challenge the mathematical skills of the students when looking at the % chance of multiple births from IVF. The lesson begins by getting the students to recognise the phrase “test tube baby” and then to link this to IVF. Extra pieces of interesting information are given throughout the lesson, such as the introduction of Louise Brown at this point. A step by step guide is used to go through the key steps in the process. Questions are continually posed to the students which get them to think and attempt to verbalise their answers such as when they are questioned whether men are needed for this process. There is a focus on key terminology throughout, such as haploid and zygote and genetic screening. Students will learn that multiple births are much more common in IVF births than from natural conception and then they will be asked to manipulate data in a mathematical task with some figures from a maternity ward. As these questions are quite difficult, this worksheet has been differentiated so that all students can access the learning. Although this has been written for GCSE students, it is suitable for use with older students.

This is an engaging and discussion filled lesson which looks at the menstrual cycle and specifically focuses on the interaction of the four hormones in the cycle. This lesson has been designed for GCSE students (ages 14 - 16 in the UK) but is suitable for older students who want a recap on this topic before going into more depth. In order to understand the cycle, it is critical that students know the roles that each of the hormones perform and also can describe how one hormone affects another. The main task of the lesson goes through the steps in the cycle, but challenges the students to use their prior knowledge of the endocrine system to add in the name of the correct hormone. At appropriate points of the lesson, time is taken to relate this topic to others in Biology, such as the use of oestrogen in the contraceptive pill and also hCG as the hormone which is detected by pregnancy tests. Students will know key landmarks in the 28 day cycle and be able to relate this back to the hormones. There are progress checks throughout the lesson but the final part of the lesson involves three understanding checks where students are challenged to apply their knowledge.

This engaging lesson presentation (51 slides) and associated worksheets uses exam questions with displayed mark schemes, quick tasks and quiz competitions to enable students to assess their understanding of the topics found within module B6 of the OCR Gateway A Combined Science specification. The topics which are specifically tested within the lesson include: Genetic engineering, Health and disease, Spread of communicable diseases and preventing the spread, Non-communicable diseases, Treating CVD and Modern advances in medicine Students will enjoy the competitions such as "Is this ENGINEERED correctly" and "COMMUNICATE the word" whilst crucially being able to recognise those areas which need their further attention

A fully resourced revision lesson which uses a range of exam questions (with explained answers), quick tasks and quiz competitions to enable the students to assess their understanding of the topics found within module 5.1.5 (Plant and animal responses) of the OCR A-level Biology A specification. The topics tested within this lesson include: Investigating tropisms The mammalian nervous system The brain Reflex actions Controlling heart rate Muscle Muscle contraction Student will enjoy the range of tasks and quiz rounds whilst crucially being able to recognise any areas which require further attention

A thought-provoking lesson presentation (34 slides) that looks at each of the stages in the development of drugs and considers the potential issues that arise at each of the stages. The lesson begins by ensuring that the students know the scientific definition of a drug and then they will be told how much is spent by the NHS alone each year on medicinal drugs so they can recognise the importance of this topic. Moving forwards, each stage in the development is considered in the appropriate detail. Students are challenged to consider some stages from both a scientific angle and a business angle so they can understand why certain animals are chosen for the testing. Key terms such as placebo and double blind trial are introduced and discussion time is written into the lesson so that insightful questions can be posed by all. There are regular progress checks throughout the lesson to allow the students to check on their understanding. This lesson has been written for GCSE students but could be used with KS3 students who might be carrying out research or a project on the topic of drugs.

A fully-resourced lesson which looks at how decomposers are involved with the process of decay. The lesson includes an engaging and detailed lesson presentation (31 slides) and an associated differentiated worksheets. The lesson begins by displaying the definitions for decomposers and detritivores and challenging students to use their bingo cards to see if they can work out the words which are being described. Students will learn how these two types of organisms work together to break down matter. Moving forwards, a worked example is used to guide students through how to calculate the rate of decay from a range of different data types. Students will be challenged to act like a travel agent for decomposers to come up with the different conditions that they require. Finally, they have to bring all of the new-found knowledge together to answer a range of summary questions. These questions are differentiated two ways so that differing abilities can access the work. There are regular progress checks throughout the lesson to allow the students to check on their understanding. This lesson has been written for GCSE students (14 - 16 year olds in the UK)