This engaging and fully-resourced lesson looks at examples of stabilising, directional and disruptive selection as the three main types of selection. The PowerPoint and accompanying resources have been designed to cover the 1st part of point 6.1.2 (e) of the OCR A-level Biology specification which states that students should be able to demonstrate and apply an understanding of the factors that affect the evolution of a species. The lesson begins by making a link to a topic from module 4 as the students are challenged to use the mark, release, recapture method to calculate numbers of rabbits with different coloured fur in a particular habitat. Sketch graphs are then constructed to show the changes in the population size in this example. A quick quiz competition is used to engage the students whilst introducing the names of the three main types of selection before a class discussion point encourages the students to recognise which specific type of selection is represented by the rabbits. Key terminology including intermediate and extreme phenotypes and selection pressure are used to emphasise their importance during explanations. A change in the environment of the habitat and a change in the numbers of the rabbits introduces directional selection before students will be given time to discuss and to predict the shape of the sketch graph for disruptive selection. Students are challenged to apply their knowledge in the final task of the lesson by choosing the correct type of selection when presented with details of a population and answer related questions. This lesson has been designed to tie in with another uploaded lesson on genetic drift which covers the second part of this specification point.

This fully-resourced REVISION lesson has been designed to enable the students to challenge their knowledge of the content of topic 16 (Inherited change) of the CIE A-level Biology specification. The engaging PowerPoint and accompanying differentiated worksheets will motivate the students whilst they assess their understanding of the content and identify any areas which may require further attention. The wide range of activities have been written to cover as much of the topic as possible but the following specification points have been given particular focus: Homologous pairs of chromosomes The meanings of haploid and diploid The behaviour of chromosomes in meiosis Crossing over and random assortment as causes of genetic variation The use of key genetic terminology The use of genetic diagrams to solve problems including autosomal and sex-linkage, dihybrid inheritance and gene interactions The use of the chi-squared test Gene mutations Genetic control of protein production in prokaryotes Gibberellins and how they cause the breakdown of DELLA proteins Due to the extensiveness of this resource, it is likely that it will take a number of lessons to go through all of the activities

This lesson guides students through the use of the chi-squared test to test the significance of differences between observed and expected results. It is fully-resourced with a detailed PowerPoint and differentiated task worksheets that have been designed to cover point 16.2 (d) of the CIE International A-level Biology specification which states that students should be able to use this statistical test to determine the significance. The lesson has been written to include a step-by-step guide that demonstrates how to carry out the test in small sections. At each step, time is taken to explain any parts which could cause confusion and helpful hints are provided to increase the likelihood of success in exam questions on this topic. Students will understand how to use the phenotypic ratio to calculate the expected numbers and then how to find the critical value in order to compare it against the chi-squared value. A worked example is used to show the working which will be required to access the marks and then the main task challenges the students to apply their knowledge to a series of questions of increasing difficulty.

This fully-resourced lesson explores how the presence of particular alleles at one locus can mask the expression of alleles at a second locus in gene interactions. The detailed and engaging PowerPoint and associated resources have been designed to cover the part of point 16.2 (b) of the CIE International A-level Biology specification which states that students should be able to use genetic diagrams to solve problems that involve gene interactions. This is a topic which students tend to find difficult, and therefore the lesson was written to split the topic into small chunks where examples of dominant, recessive and complimentary gene interactions are considered, discussed at length and then explained. Understanding checks, in various forms, are included throughout the lesson so that students can assess their progress and any misconceptions are immediately addressed. There are regular links to related topics such as dihybrid inheritance so that students can meet the challenge of interpreting genotypes and link to the different types of interactions

This fully-resourced lesson explores the inheritance of genetic characteristics that involve multiple alleles and codominant alleles. The engaging and detailed PowerPoint and differentiated worksheets have been designed to cover the part of point 16.2 (b) of the CIE International A-level Biology specification which states that students should be able to use genetic diagrams to solve problems which involve codominance and multiple alleles. The main part of the lesson uses the inheritance of the ABO blood groups to demonstrate how the three alleles that are found at the locus on chromosome 9 and the codominance of the A and B alleles affects the phenotypes. Students are guided through the construction of the different genotypes and how to interpret the resulting phenotype. They are challenged to use a partially completed pedigree tree to determine the blood group for some of the family members and to explain how they came to their answer. To further challenge their ability to apply their knowledge, a series of questions about multiple alleles and codominance in animals that are not humans are used. All of the questions are followed by clear, visual mark schemes to allow the students to assess their progress and address any misconceptions

This fully-resourced lesson explores sex-linkage and specifically the inheritance of sex-linked diseases in humans and then challenges the students to apply their knowledge to examples in other animals. The detailed PowerPoint and associated differentiated resources have been designed to cover the part of point 16.2 (b) of the CIE International A-level Biology specification which states that students should be able to use genetic diagrams to solve problems involving sex-linkage. Key genetic terminology is used throughout and the lesson begins with a check on their ability to identify the definition of homologous chromosomes. Students will recall that the sex chromosomes are not fully homologous and that the smaller Y chromosome lacks some of the genes that are found on the X. This leads into one of the numerous discussion points, where students are encouraged to consider whether females or males are more likely to suffer from sex-linked diseases. In terms of humans, the lesson focuses on haemophilia and red-green colour blindness and a step-by-step guide is used to demonstrate how these specific genetic diagrams should be constructed and how the phenotypes should then be interpreted. The final tasks of the lesson challenge the students to carry out a dihybrid cross that involves a sex-linked disease and an autosomal disease before applying their knowledge to a question about chickens and how the rate of feather production in chicks can be used to determine gender. All of the tasks are differentiated so that students of differing abilities can access the work and all exam questions have fully-explained, visual markschemes to allow them to assess their progress and address any misconception

This clear and concise lesson explains how the inheritance of two or more genes that have loci on the same chromosome demonstrates autosomal linkage. The engaging PowerPoint and associated resource have been designed to cover the part of point 16.2 (b) of the CIE International A-level Biology specification which states that students should be able to use genetic diagrams to solve problems that involve autosomal linkage. This is a topic which can cause confusion for students so time was taken in the design to split the concept into small chunks. There is a clear focus on how the number of original phenotypes and recombinants can be used to determine linkage and suggest how the loci of the two genes compare. Important links to other topics such as crossing over in meiosis are made to enable students to understand how the random formation of the chiasma determines whether new phenotypes will be seen in the offspring or not. Linkage is an important cause of variation and the difference between observed and expected results and this is emphasised on a number of occasions. The main task of the lesson acts as an understanding check where students are challenged to analyse a set of results involving the inheritance of the ABO blood group gene and the nail-patella syndrome gene to determine whether they have loci on the same chromosome and if so, how close their loci would appear to be.

This lesson guides students through the use of genetic diagrams to solve problems involving monohybrid and dihybrid crosses. The engaging PowerPoint and accompanying worksheets have been designed to cover the part of topic 16.2 (b) of the CIE A-level Biology specification which involves the inheritance of one or two genes As you can see from the cover image, this lesson uses a step by step guide to go through each important stage of drawing the genetic cross. Extra time is taken over step 2 which involves writing out the different possible gametes that a parent can produce. This is the step where students most commonly make mistakes so it is critical that the method is understood. Helpful hints are also given throughout, such as only writing out the different possible gametes in order to avoid creating unnecessary work. Students are shown how to answer an example question so that they can visualise how to set out their work before they are challenged to try two further questions. This first of these is differentiated so that even those students who find this very difficult are able to access the learning. The final question will enable the students to come up with the ratio 9:3:3:1 and they will be shown how they can recognise when this should be the expected ratio as this links to the chi-squared test which is covered later in the topic.

This fully-resourced lesson guides students through the use of the Hardy-Weinberg equation to calculate the frequency of alleles, genotypes and phenotypes in a population. Both the detailed PowerPoint and differentiated practice questions on a worksheet have been designed to cover the 2nd part of point 7.2 of the AQA A-level Biology specification which expects students to be able to use this mathematical model The lesson begins by looking at the equation and ensuring that students understand the meaning of each of the terms. The recessive condition, cystic fibrosis, is used as an example so that students can start to apply their knowledge and assess whether they understand which genotypes go with which term. Moving forwards, a step-by-step guide is used to show students how to answer a question. Tips are given during the guide so that common misconceptions and mistakes are addressed immediately. The rest of the lesson gives students the opportunity to apply their knowledge to a set of 3 questions, which have been differentiated so that all abilities are able to access the work and be challenged.

This lesson focuses on the use and explanation of key genetic terms which will support students in their understanding of the topic 16 (inherited change) of the CIE International A-level Biology specification. In this topic, students are expected to use genetic diagrams to solve problems and this is only possible with a clear understanding of the genetic terminology that will be used in related exam questions. As some of these terms were met at GCSE, this fully-resourced lesson has been designed to include a wide range of activities that build on this prior knowledge and provide clear explanations as to their meanings as well as numerous examples of their use in both questions and exemplary answers. The main task provides the students with an opportunity to apply their understanding by recognising a dominance hierarchy in a multiple alleles characteristic and then calculating a phenotypic ratio when given a completed genetic diagram. Other tasks include prior knowledge checks, discussion points to encourage students to consider the implementation of the genetic terms and quiz competitions to introduce new terms, maintain engagement and act as an understanding check. The 16 terms are genome, gene, chromosome, gene locus, homologous chromosomes, alleles, dominant, recessive, genotype, codominance, multiple alleles, autosomes, sex chromosomes, phenotype, homozygous and heterozygous

This lesson acts as an introduction to part b of module 6.1.2 of the OCR A-level Biology A specification and focuses on 16 key genetic terms. In this module, students are expected to be able to demonstrate and apply their knowledge and understanding of genetic diagrams and phenotypic ratios to show patterns of inheritance and this is only possible with a clear understanding of the genetic terminology that will be used in related exam questions. As some of these terms were met at GCSE, this fully-resourced lesson has been designed to include a wide range of activities that build on this prior knowledge and provide clear explanations as to their meanings as well as numerous examples of their use in both questions and exemplary answers. The main task provides the students with an opportunity to apply their understanding by recognising a dominance hierarchy in a multiple alleles characteristic and then calculating a phenotypic ratio when given a completed genetic diagram. Other tasks include prior knowledge checks, discussion points to encourage students to consider the implementation of the genetic terms and quiz competitions to introduce new terms, maintain engagement and act as an understanding check. The 16 terms are genome, gene, chromosome, gene locus, homologous chromosomes, alleles, dominant, recessive, genotype, codominance, multiple alleles, autosomes, sex chromosomes, phenotype, homozygous and heterozygous

This lesson guides students through the use of the chi-squared test to determine the significance of the difference between observed and expected results. It is fully-resourced with a detailed PowerPoint and differentiated task worksheets that have been designed to cover the part of point 7.1 of the AQA A-level Biology specification which states that students should be able to use the test to compare the goodness of fit between the observed phenotypic ratios and expected ratios. The lesson has been written to include a step-by-step guide that demonstrates how to carry out the test in small sections. At each step, time is taken to explain any parts which could cause confusion and helpful hints are provided to increase the likelihood of success in exam questions on this topic. Students will understand how to use the phenotypic ratio to calculate the expected numbers and then how to find the critical value in order to compare it against the chi-squared value. A worked example is used to show the working which will be required to access the marks and then the main task challenges the students to apply their knowledge to a series of questions of increasing difficulty. This is the final lesson of topic 7.1 (inheritance) and links are made throughout the lesson to earlier parts of this topic such as dihybrid inheritance as well as to earlier topics such as meiosis.

This fully-resourced lesson explores how the presence of particular alleles at one locus can mask the expression of alleles at a second locus in epistasis. The detailed and engaging PowerPoint and associated resources have been designed to cover the part of point 7.1 of the AQA A-level specification which states that students should be able to use fully-labelled genetic diagrams to predict or interpret the results of crosses involving epistasis. This is a topic which students tend to find difficult, and therefore the lesson was written to split the topic into small chunks where examples of dominant, recessive and complimentary epistasis are considered, discussed at length and then explained. Understanding checks, in various forms, are included throughout the lesson so that students can assess their progress and any misconceptions are immediately addressed. There are regular links to related topics such as dihybrid inheritance so that students can meet the challenge of interpreting genotypes as well as recognising the different types of epistasis. The lesson has been designed to tie in with the other uploaded lessons on the topic of inheritance (7.1), so if you like the quality of this lesson please take a moment to look at these too

This clear and concise lesson explains how the inheritance of two or more genes that have loci on the same autosome demonstrates autosomal linkage. The engaging PowerPoint and associated resource have been designed to cover the part of point 7.1 of the AQA A-level Biology specification which states that students should be able to use fully-labelled genetic diagrams to interpret the results of crosses involving autosomal linkage. This is a topic which can cause confusion for students so time was taken in the design to split the concept into small chunks. There is a clear focus on how the number of original phenotypes and recombinants can be used to determine linkage and suggest how the loci of the two genes compare. Important links to other topics such as crossing over in meiosis are made to enable students to understand how the random formation of the chiasma determines whether new phenotypes will be seen in the offspring or not. Linkage is an important cause of variation and the difference between observed and expected results and this is emphasised on a number of occasions. The main task of the lesson acts as an understanding check where students are challenged to analyse a set of results involving the inheritance of the ABO blood group gene and the nail-patella syndrome gene to determine whether they have loci on the same chromosome and if so, how close their loci would appear to be. This lesson has been written to tie in with the other 6 lessons from topic 7.1 (Inheritance) and these have also been uploaded

This fully-resourced lesson explores the inheritance of sex-linked diseases in humans and then challenges the students to apply their knowledge to examples in other animals. The detailed PowerPoint and associated differentiated resources have been designed to cover the part of point 7.1 of the AQA A-level specification which states that students should be able to use fully-labelled genetic diagrams to predict the results of crosses involving sex-linkage. Key genetic terminology is used throughout and the lesson begins with a check on their ability to identify the definition of homologous chromosomes. Students will recall that the sex chromosomes are not fully homologous and that the smaller Y chromosome lacks some of the genes that are found on the X. This leads into one of the numerous discussion points, where students are encouraged to consider whether females or males are more likely to suffer from sex-linked diseases. In terms of humans, the lesson focuses on haemophilia and red-green colour blindness and a step-by-step guide is used to demonstrate how these specific genetic diagrams should be constructed and how the phenotypes should then be interpreted. The final tasks of the lesson challenge the students to carry out a dihybrid cross that involves a sex-linked disease and an autosomal disease before applying their knowledge to a question about chickens and how the rate of feather production in chicks can be used to determine gender. All of the tasks are differentiated so that students of differing abilities can access the work and all exam questions have fully-explained, visual markschemes to allow them to assess their progress and address any misconceptions

This fully-resourced lesson covers the part of specification point 7.1 of the AQA A-level Biology specification which states that students should be able to use genetic diagrams to interpret the results of crosses involving codominant and multiple alleles. The inheritance of ABO blood groups has three alleles at the gene locus on chromosome 9 where the alleles for A and B are codominant and this is used to introduce the two concepts. A range of tasks challenges the students to write genotypes, and construct genetic diagrams to calculate phenotypic ratios. They have to apply their understanding by working out the blood groups for a number of family members when presented with an incomplete pedigree tree. The final task of the lesson challenges their application skills further but this time, the animals involved are not humans. Each question is followed by a detailed, visual mark scheme so students can assess their progress and address any misconceptions

This fully-resourced lesson challenges the students to use fully labelled genetic diagrams to interpret the results of monohybrid and dihybrid crosses as detailed in topic 7.1 (Inheritance) of the AQA A-level Biology specification. Step-by-step guides are used to demonstrate how diagrams for the inheritance of one and two genes should be constructed and a focus is given to the areas where students commonly make mistakes, such as in writing out the gametes. The main task of each section of the lesson provides an opportunity for the students to apply their understanding by calculating phenotypic ratios. All of the questions have fully-explained mark schemes and students can assess their progress and address any misconceptions immediately. Key genetic terminology is used throughout the lesson and mirrors that used in actual exam questions.