This lesson describes the concept of homeostasis using negative feedback control and also describes the role of positive feedback. The PowerPoint and accompanying resources have been designed to cover specification points (a & b) in topic 7 of A2 unit 3 of the WJEC A-level Biology specification and explains how this feedback control maintains systems within narrow limits but has also been planned to provide important details for upcoming topics such as osmoregulation. The normal ranges for blood glucose concentration, blood pH and body temperature are introduced at the start of the lesson to allow students to recognise that these aspects have to be maintained within narrow limits. A series of exam-style questions then challenge their recall of knowledge from AS units 1 & 2 and the earlier topics in A2 unit 3 as they have to explain why it’s important that each of these aspects is maintained within these limits. The students were introduced to homeostasis at GCSE, so this process is revisited and discussed, to ensure that students are able to recall that this is the maintenance of a state of dynamic equilibrium. A quick quiz competition is used to reveal negative feedback as a key term and students will learn how this form of control reverses the original change and biological examples are used to emphasise the importance of this system for restoring levels to the limits (and the optimum). The remainder of the lesson explains how positive feedback differs from negative feedback as it increases the original change and the role of oxytocin in birth and the movement of sodium ions into a neurone are used to exemplify the action of this control system.

This detailed lesson describes the absorption of water, the movement through the root and the role of the endodermis. Both the PowerPoint and accompanying resource have been designed to cover specification points (j, k & l) in topic 3 of AS unit 2 of the WJEC A-level Biology specification and includes descriptions of the apoplast, symplast and vacuolar pathways and the Casparian strip. The lesson begins by looking at the specialised features of the root hair cell so that students can understand how these epidermal cells absorb water and mineral ions from the soil. Moving forwards, students are introduced to key terminology such as epidermis and root cortex before time is taken to look at the different pathways that water and minerals use to transverse across the cortex. Discussion points are included throughout the lesson to encourage the students to think about each topic in depth and challenges them to think about important questions such as why the apoplast pathway is needed for the water carrying the ions. The main part of the lesson focuses on the role of the endodermis in the transport of the water and ions into the xylem. Students will be introduced to the Casparian strip and will learn how this layer of cells blocks the apoplast pathway. A step by step method using class questions and considered answers is used to guide them through the different steps and to support them when writing the detailed description. This lesson has been written to tie in with the next lesson on the pathways and mechanisms by which water and mineral ions are transported to the leaves.

This lesson describes the movement of water from the root to the leaf and includes the transpiration stream and the cohesion-tension theory. The PowerPoint and accompanying resources have been designed to cover point (n) of topic 3 in AS unit 2 of the WJEC A-level Biology specification This lesson has been written to follow on from a previous lesson, which finished with the description of the transport of the water and mineral ions from the endodermis to the xylem. Students are immediately challenged to use this knowledge to understand root pressure and the movement by mass flow down the pressure gradient. Moving forwards, time is taken to study the details of transpiration pull and the interaction between cohesion, tension and adhesion in capillary action is explained. Understanding is constantly checked through a range of tasks and prior knowledge checks are also written into the lesson to challenge the students to make links to previously covered topics such as the structure of the transport tissues. The final part of the lesson considers the journey of water through the leaf and ultimately out of the stomata in transpiration. A step by step guide using questions to discuss and answer as a class is used to support the students before the final task challenges them to summarise this movement out of the leaf.

This lesson describes how the cells of the proximal tubule in the nephron of the kidney are adapted for reabsorption. The PowerPoint and accompanying resource which is filled with tasks have been designed to cover specification point [e] in topic 7 of A2 unit 3 of the WJEC A-level Biology specification and builds on the knowledge gained in the previous lessons on the structure of the nephron and the functions of the mammalian kidney. The lesson begins by challenging the students to recall the substances that are found in the glomerular filtrate so that each of them can be considered over the course of the rest of the lesson. Moving forwards, the first of the numerous discussion points which are included in the lesson is used to get students to predict the component of the filtrate which won’t be found in the urine when they are presented with pie charts from each of these situations. Upon learning that glucose is 100% reabsorbed, along with most of the ions and some of the water, the rest of the lesson focuses on describing the relationship between the structure of the proximal tubule and the function of selective reabsorption. Again, this section begins by encouraging the students to discuss and to predict which structures they would expect to find in a section of the kidney if the function is to reabsorb. They are given the chance to see the structure (as shown in the cover image) before each feature is broken down to explain its importance. Time is taken to look at the role of the cotransporter proteins to explain how this allows glucose, along with sodium ions, to be reabsorbed from the lumen of the PCT into the epithelial cells. The final part of the lesson focuses on urea and how the concentration of this substance increases along the tubule as a result of the reabsorption of some of the water.

An informative lesson presentation (30 slides) that ensures that students know the meaning of the independent, dependent and control variables in an investigation and are able to identify them. Students are challenged to use their definitions to spot the independent and dependent variable from an investigation title. Moving forwards, they are shown how they can use tables and graphs to identify them. The rest of the lesson focuses on the control variables and how these have to be controlled to produce valid results This lesson is suitable for students of all ages studying Science as it is such a key skill

This detailed lesson looks at the structure of the mitochondrion and explains how the specific features allow the stages of aerobic respiration to take place in this organelle. The engaging PowerPoint and accompanying resource have been designed to cover point 5.2.2 (b) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of the inner and outer mitochondrial membranes, cristae, matrix and mitochondrial DNA. The lesson begins with a version of “GUESS WHO” where students have to use a series of structural clues to whittle the 6 organelles down to just 1 - the mitochondrion. Moving forwards, the key components of the organelle are identified on a diagram. Students are introduced to the stages of respiration so that they can make a link to the parts of the cell and the mitochondria where each stage occurs. Students will learn that the presence of decarboxylase and dehydrogenase enzymes in the matrix along with coenzymes and oxaloacetate allows the Link reaction and the Krebs cycle to run. Finally, time is taken to introduce the electron transport chain and the enzyme, ATP synthase, so that students can begin to understand how the flow of protons across the inner membrane results in the production of ATP. This lesson has been designed to tie in with the other uploaded lessons on the stages of respiration.

A really engaging and detailed lesson presentation (44 slides) and associated differentiated worksheets that looks at communicable diseases in plants and challenges students to diagnose these diseases in plants. During the lesson the students will take on the role of the “Treeage” (triage) nurse and have to direct each plant to the correct ward in the “CASUALTREE” according to the pathogen which has infected them. They will also have to explain how the symptoms which they have identified were caused and explain the future for this plant, during their time as the “Tree surgeon”. The three diseases included in the lesson are tobacco mosaic virus, crown gall disease and powdery mildew disease. There are regular progress checks throughout the lesson so that students can assess their understanding and there is a set homework included as part of the lesson. This lesson has been designed for GCSE students but is also suitable for A-level students looking at the communicable diseases topic

This detailed lesson describes the principles of DNA sequencing and has been designed to cover the first part of point 6.1.3 (a) of the OCR A-level Biology A specification. Fred Sanger’s chain termination method is used as the example to guide the students through the details of each step. The lesson begins with a focus on the common ingredients of the process such as DNA polymerase, DNA nucleotides and primers. Links are made to module 2.1.3 where nucleic acids were initially met through a series of prior knowledge check questions. Time is then taken to explain why these short lengths of synthesised nucleotides are necessary and this will support students when primers are met in the PCR and genetic engineering. Moving forwards, students will recognise how the modification to the nucleotide means that the chain terminates once a modified nucleotide is added into the sequence and that these have been radioactively labelled. Gel electrophoresis is introduced and an outline of the process given to provide knowledge to build on when this is encountered later in the module. A series of exam-style questions allow students to assess their understanding of this potentially difficult topic before students are encouraged to consider the limitations of the method so they are prepared to meet the new methods in upcoming lessons. A number of quiz competitions run throughout the lesson to maintain engagement and to introduce terms and values in a memorable way

A detailed lesson presentation (37 slides) and associated worksheets that guide students through the DNA sequencing method called pyrosequencing. The lesson focusses on the numerous enzymes and substrates which are involved in the cascade of events which eventually leads to the production of light when the conversion from luciferin to oxyluciferin occurs. A step by step guide is used to show the students how these events occur and the different outcomes are explored. There are regular progress checks throughout the lesson so that students can assess their understanding of this topic and the links to similar topics. This lesson has been designed for A-level students and above

An engaging and informative lesson presentation (30 slides) that looks at some of the uses of stem cells in medicine. The lesson begins by challenging the students to define some key terms such as undifferentiated which are associated with these cells. Moving forwards, students will look at the uses of embryonic stem cells including in the treatment of Parkinson’s disease and for tests in drug trials. Students are challenged to consider for homework why the uses of these cells remains controversial. This lesson is designed for GCSE students

A detailed and engaging lesson presentation (52 slides) and accompanying worksheet that looks at competition between organisms and the different types of relationships that exist as a result of this interaction. The lesson begins by looking at the meaning of the biological term, "competition", and then introduces this when it occurs between the same species and different species. Students are challenged to consider the different resources that animals compete for before an activity based competition is used to get them to recognise how this competition can cause changes to the population size. Moving forwards, students will meet the three main types of ecological relationship and look at them in greater detail, with predation being a main focus. There are regular progress checks throughout the lesson (with displayed answers) so that students can assess their understanding. This lesson has been designed for GCSE students but can be used with more-able KS3 students who are looking at ecosystems and the relationships that exist within them

A fully resourced lesson which includes an informative lesson presentation (34 slides) and differentiated worksheets that show students how to convert between units so they are confident to carry out these conversions when required in Science questions. The conversions which are regularly seen at GCSE are covered as well as some more obscure ones which students have to be aware of. A number of quiz competitions are used throughout the lesson to maintain motivation and to allow the students to check their progress in an engaging way This lesson has been designed for GCSE students but is suitable for KS3

A fully-resourced lesson that looks at the topic of osmosis and how the movement of water between a cell and the solution can affect the appearance of an animal and a plant cell. This lesson includes a detailed and engaging lesson presentation (42 slides) and differentiated worksheets that include exam questions that can be set as homework. There is a lot of key terminology associated with this topic and time is taken to ensure that students understand the meaning of each of these terms before moving forwards. Students are introduced to the different types of solutions and then a step-by-step guide is used to show them how to compare the water potential of the solution and the cell and then how this will determine which was water moves. The main task is differentiated so that students are challenged and can access the work. This lesson has been designed for GCSE students (14 - 16 year olds in the UK) but is also suitable for A-level students

An engaging lesson presentation and associated worksheet that looks at the use of antibiotics to treat bacterial infections and the raises the issue of the potential over-use of these substances. The lesson begins by getting the students to recognise the difference between three key terms that begin with anti (antibiotics, antivirals, antiseptics). Students will be introduced to the idea that antibiotics are specific to a small range of bacteria and therefore the correct one has to be selected before being prescribed. Moving forwards, students will meet the idea of the zone of inhibition and will understand how the size of this zone can be used as an indicator to the effectiveness of the treatment. Students are shown how to calculate the size of the zone and then are tested on their ability to apply this mathemetical knowledge. Finally, time is taken to look at the links to the topic of natural selection to explain how some bacteria are resistant to certain antibiotics. There are regular progress checks throughout the lesson so that students can assess their understanding. This lesson has been designed for GCSE students but could be used as an introduction with A-level Biology students who are about to begin the topic of immunity.

A fully-resourced lesson which looks at the structures of arteries, veins and capillaries and ensures that students can relate these features to their respective functions. The lesson includes an engaging lesson presentation (41 slides) and a differentiated worksheet The lesson begins by getting the students to come up with a really simple rule to remind themselves that arteries carry blood away from the heart. They are then challenged to extend this definition by considering the pressure of the blood found in arteries. Students will learn that most arteries carry oxygenated blood but will consider and recall the artery which is the exception to the rule. Students are shown a diagram of the basic structure of the artery and the reasons for the narrow lumen and thick muscular wall are explained. Moving forwards, students are challenged to use the work on arteries to sketch a diagram of a vein and to explain why they have given this vessel certain features. A quick competition is then used to check their understand of the work so far whilst introducing valves and again they are given a chance to work out which blood vessel would need these structures in their lumen. The remainder of the lesson focuses on the capillary and time is taken to relate the features to an actual example involving the alveoli of the lungs. There are regular progress checks throughout the lesson to allow the students to check on their understanding. As always, the lesson finishes with a slide containing advanced terminology so that students who have aspirations to take A-level Biology can extend and deepen their knowledge

A resourced lesson which looks at three of the main components of blood and ensures that students can relate their features to their function. The lesson includes an engaging lesson presentation (31 slides) and an associated worksheet The lesson begins by challenging the students to recognise blood from a description of some of its contents. This will enable students to identify some of the substances like hormones and urea that are carried in the plasma. Moving forwards, the rest of the lesson takes a format where the students have to act as recruitment consultants. They have been given 3 job roles to fill and once they have decided on the right candidates for the job, they need to be able to explain why these have been chosen. Students will go study the red and white blood cells and platelets, focusing on how their different specialised features enable them to effectively carry out their respective functions. Students will be able to compare the cells in terms of size, number of nuclei and ultimately explain why they have their features. There are regular progress checks throughout the lesson to allow the students to check on their understanding. This lesson has been designed for GCSE students but is perfectly suitable to be used with KS3 students who are studying the circulatory system

A resourced lesson which looks at the chemical reaction that is aerobic respiration and ensures that students can apply their knowledge to application questions which challenge them to make links to related topics. The lesson includes an engaging lesson presentation (27 slides) and an associated worksheet containing questions. The lesson begins by challenging the students to recognise a definition for breathing and a definition for respiration. This is aimed at helping them to understand that these are different processes as this is a common misconception made by students. Moving forwards, key details about aerobic respiration are introduced to the students through a range of tasks which include competitions to maintain engagement. Time is taken to ensure that students become familiar with ATP and understand that this is the energy store which will be broken down to release energy for the activities that occur in a living organism. The remainder of the lesson challenges the students to take their new found knowledge of aerobic respiration and apply it to range of unfamiliar situations such as explaining why a root hair cell would have such a large number of mitochondria. There are regular progress checks throughout the lesson to allow the students to check on their understanding. As always, the lesson finishes with a slide containing advanced terminology so that students who have aspirations to take A-level Biology can extend and deepen their knowledge

A fully- resourced lesson which looks at the chemical reaction that is anaerobic respiration and ensures that students can understand why this form of respiration can only be used for short periods of time. The lesson includes an engaging lesson presentation (39 slides), a newspaper article and application questions. The lesson begins by challenging the students to recall information about aerobic respiration to recognise that the sole reactant of anaerobic respiration is glucose. A newspaper article about two atheletes from the 10000m race has been written to challenge the students to recognise why one of the athletes wouldnt be able to compete again in the near future whilst the other could. As a result, students will be introduced to lactic acid and will learn how this poisonous substance prevents muscle contraction and causes cramps. Time is taken to ensure that students are familiar with ATP and specifically that they recognise that a much lower yield is produced in this type of respiration. A perfect opportunity is taken to get the students to carry out a mathematical calculation to compare the yields. Oxygen debt is discussed and related back to the original newspaper article. Finally, anaerobic respiration in plants and yeast is considered in terms of fermentation and the word and symbol equation is written so that it can be compared to those from animals. There are regular progress checks throughout the lesson to allow the students to check on their understanding. The lesson has been written for GCSE students but could be used with higher ability KS3 students or A-level students who want a recap before covering the topic in greater detail on their course.

A fully-resourced lesson which looks at the structure of the human heart and its associated vessels and ensures that students know the journey which blood takes through this organ. The lesson includes an engaging lesson presentation (25 slides), a diagram to label and a worksheet to summarise the journey. The lesson begins with a bit of fun as students see the script to part of an episode from Friends. Students will recognise the alternative definition of the heart and ultimately recall that the function of this organ is to pump blood around the body. Moving forwards, the main task of the lesson involves labelling the four chambers and the blood vessels which bring blood towards and away from the heart. Students are given useful hints along the way to enable them to discover the answers rather than simply being given a finished diagram. Time is taken to look at the valves and discuss their function so that students can understand this role when they encounter them in veins. The lesson concludes with one final task that challenges the students to detail the journey of blood through the heart. There are regular progress checks throughout the lesson to allow the students to check on their understanding. As always, the lesson finishes with a slide containing advanced terminology so that students who have aspirations to take A-level Biology can extend and deepen their knowledge

This concise lesson has been designed to cover the content found in specification point 4.1.3.2 (Osmosis) of topic 1 of the AQA GCSE Biology & Combined Science specifications. This resource contains an engaging PowerPoint (23 slides) and accompanying worksheets, some of which have been differentiated to help students of different abilities to take on the task at hand. The lesson begins with the introduction of the term, osmosis, and then students are challenged to use their knowledge of diffusion to write a definition for this method of movement of water molecules. A series of questions which check understanding are included at this early point of the lesson to ensure that the key points are known and any misconceptions are quickly addressed. Students are also challenged with an application question as these can often cause them the most problems. Moving forwards, the rest of the lesson focuses on an osmosis investigation. Scientific skills are tested during a range of tasks as well as numerical skills and guidance is given on how to calculate percentage change. As stated at the top, this lesson has been designed for GCSE-aged students who are studying the AQA GCSE Biology course, but can be used with younger students who are keen to learn about osmosis