This lesson describes the structure and function of synapses in nerve impulse transmission and focuses on acetylcholine as a neurotransmitter. The PowerPoint and accompanying resources have been designed to cover point 8.6 (i) of the Edexcel International A-level Biology specification, using a cholinergic synapse as the main example The lesson begins by using a version of the WALL from “Only Connect” which asks the students to group 12 words into three groups of 4. Not only will this challenge their prior knowledge from topics earlier in this topic but it will also lead to the discovery of four of the structures that are found in a synapse. Moving forwards, students are introduced to acetylcholine as the neurotransmitter involved at cholinergic synapses and they will start to add labels to the structures found in the pre-synaptic bulb. Time is taken to focus on certain structures such as the voltage gated channels as these types of channel were met previously when looking at the depolarisation of a neurone. There is plenty of challenge and discovery as students are pushed to explain why organelles like mitochondria would be found in large numbers in the bulb. With this process being a cascade of events, a bullet point format is used to ensure that the key content is taken in by the students and again key points like exocytosis and the action of acetylcholinesterase are discussed further. Understanding checks and prior knowledge checks are included throughout the lesson so that students can not only assess their progress against the current topic but also see whether they can make links to earlier topics.

This lesson describes how the structure of arteries, arterioles, capillaries, venules and veins in the mammalian circulatory system relate to their functions. The PowerPoint and accompanying resources are part of the second lesson in a series of 2 lessons which have been designed to cover specification point (b) of topic 3 in AS unit 2 of the WJEC A-level Biology A specification. The first lesson in this series covers the structure and function of the human heart and its associated blood vessels This lesson has been written to build on any prior knowledge from GCSE or earlier in this topic to enable students to fully understand why a particular type of blood vessel has particular features. Students will be able to make the connection between the narrow lumen and elastic tissue in the walls of arteries and the need to maintain the high pressure of the blood. A quick version of the GUESS WHO game is used to introduce smooth muscle and collagen in the tunica media and externa and again the reason for their presence is explored and explained. Moving forwards, it is quite likely that some students will not be aware of the transition vessels that are the arterioles. This section begins with an understanding of the need for these vessels because the structural and functional differences between arteries and capillaries is too significant. The action of the smooth muscle in the walls of these vessels is discussed and students will be challenged to describe a number of situations that would require blood to be redistributed. The middle part of the lesson looks at the role of the capillaries in exchange and links are made to diffusion to ensure that students can explain how the red blood cells pressing against the endothelium results in a short diffusion distance. The remainder of the lesson considers the structure of the veins and students are challenged to explain how the differences to those observed in arteries is due to the lower blood pressure found in these vessels.

This lesson describes the structure and function of the human heart and names the blood vessels associated with this organ . The PowerPoint and accompanying resources are part of the first lesson in a series of 2 lessons that have been designed to cover point (b) in topic 3 of AS unit 2 of the WJEC A-level Biology specification As this topic was covered at GCSE, the lesson has been planned to build on this prior knowledge whilst adding the key details which will enable students to provide A-level standard answers. The primary focus is the identification of the different structures of the heart but it also challenges their ability to recognise the important relationship to function. For example, time is taken to ensure that students can explain why the atrial walls are thinner than the ventricular walls and why the right ventricle has a thinner wall than the left ventricle. Opportunities are taken throughout the lesson to link this topic to the others found in topic 3 including those which have already been covered like circulatory systems as well as those which are upcoming such as the initiation of heart action. There is also an application question where students have to explain why a hole in the ventricular septum would need to be repaired if it doesn’t naturally close over time.

This lesson describes the Krebs cycle as a stage of aerobic respiration that liberates energy to produce ATP and reduced NAD and releases carbon dioxide. The PowerPoint and accompanying resource have been designed to cover specification point [c] in topic 3 of A2 unit 3 of the WJEC A-level Biology specification. The lesson begins with a version of the Impossible game where students have to spot the connection between 8 of the 9 terms and will ultimately learn that this next stage is called the Krebs cycle. The main part of the lesson challenges the students to use descriptions of the main steps of the cycle to continue their diagram of the reactions. Students are continually exposed to key terminology such as decarboxylation and dehydrogenation and they will learn where carbon dioxide is lost and reduced NAD and FAD are generated. They will also recognise that ATP is synthesised by substrate level phosphorylation. The final task challenges them to apply their knowledge of the cycle to work out the numbers of the different products and to calculate the number of ATP that must be produced in the next stage This lesson has been designed to tie in with the other uploaded lessons on glycolysis and the electron transport chain (in oxidative phosphorylation).

This lesson describes the concept of homeostasis using negative feedback control and also describes the role of positive feedback. The PowerPoint and accompanying resources have been designed to cover specification points (a & b) in topic 7 of A2 unit 3 of the WJEC A-level Biology specification and explains how this feedback control maintains systems within narrow limits but has also been planned to provide important details for upcoming topics such as osmoregulation. The normal ranges for blood glucose concentration, blood pH and body temperature are introduced at the start of the lesson to allow students to recognise that these aspects have to be maintained within narrow limits. A series of exam-style questions then challenge their recall of knowledge from AS units 1 & 2 and the earlier topics in A2 unit 3 as they have to explain why it’s important that each of these aspects is maintained within these limits. The students were introduced to homeostasis at GCSE, so this process is revisited and discussed, to ensure that students are able to recall that this is the maintenance of a state of dynamic equilibrium. A quick quiz competition is used to reveal negative feedback as a key term and students will learn how this form of control reverses the original change and biological examples are used to emphasise the importance of this system for restoring levels to the limits (and the optimum). The remainder of the lesson explains how positive feedback differs from negative feedback as it increases the original change and the role of oxytocin in birth and the movement of sodium ions into a neurone are used to exemplify the action of this control system.

This lesson describes how the cells of the proximal tubule in the nephron of the kidney are adapted for reabsorption. The PowerPoint and accompanying resource which is filled with tasks have been designed to cover specification point [e] in topic 7 of A2 unit 3 of the WJEC A-level Biology specification and builds on the knowledge gained in the previous lessons on the structure of the nephron and the functions of the mammalian kidney. The lesson begins by challenging the students to recall the substances that are found in the glomerular filtrate so that each of them can be considered over the course of the rest of the lesson. Moving forwards, the first of the numerous discussion points which are included in the lesson is used to get students to predict the component of the filtrate which won’t be found in the urine when they are presented with pie charts from each of these situations. Upon learning that glucose is 100% reabsorbed, along with most of the ions and some of the water, the rest of the lesson focuses on describing the relationship between the structure of the proximal tubule and the function of selective reabsorption. Again, this section begins by encouraging the students to discuss and to predict which structures they would expect to find in a section of the kidney if the function is to reabsorb. They are given the chance to see the structure (as shown in the cover image) before each feature is broken down to explain its importance. Time is taken to look at the role of the cotransporter proteins to explain how this allows glucose, along with sodium ions, to be reabsorbed from the lumen of the PCT into the epithelial cells. The final part of the lesson focuses on urea and how the concentration of this substance increases along the tubule as a result of the reabsorption of some of the water.

An informative lesson presentation (30 slides) that ensures that students know the meaning of the independent, dependent and control variables in an investigation and are able to identify them. Students are challenged to use their definitions to spot the independent and dependent variable from an investigation title. Moving forwards, they are shown how they can use tables and graphs to identify them. The rest of the lesson focuses on the control variables and how these have to be controlled to produce valid results This lesson is suitable for students of all ages studying Science as it is such a key skill

This clear and concise lesson explains how the inheritance of two or more genes that have loci on the same autosome demonstrates autosomal linkage. The engaging PowerPoint and associated resource have been designed to cover the part of point 6.1.2 (b[ii]) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the use of phenotypic ratios to identify autosomal linkage. This is a topic which can cause confusion for students so time was taken in the design to split the concept into small chunks. There is a clear focus on how the number of original phenotypes and recombinants can be used to determine linkage and suggest how the loci of the two genes compare. Important links to other topics such as crossing over in meiosis are made to enable students to understand how the random formation of the chiasma determines whether new phenotypes will be seen in the offspring or not. Linkage is an important cause of variation and the difference between observed and expected results and this is emphasised on a number of occasions. The main task of the lesson acts as an understanding check where students are challenged to analyse a set of results involving the inheritance of the ABO blood group gene and the nail-patella syndrome gene to determine whether they have loci on the same chromosome and if so, how close their loci would appear to be. This lesson has been written to tie in with the other lessons from module 6.1.2 (Patterns of Inheritance)

A whole lesson on the topic of active transport which includes a concise lesson presentation (20 slides) and a set of questions that are used to check on the students’ understanding. This lesson is designed for GCSE students (14 - 16 year olds in the UK) but could be used with A-level students who are covering the topic of movement across cell membranes. The main focus of the lesson is to get students to understand that this is an active process which moves substances against the concentration gradient and therefore needs energy for this process. The final part of the lesson looks at the different types of questions that can accompany this topic and a step-by-step guide is used to answer a difficult longer answer question as a class.

A fully-resourced lesson that looks at the topic of osmosis and how the movement of water between a cell and the solution can affect the appearance of an animal and a plant cell. This lesson includes a detailed and engaging lesson presentation (42 slides) and differentiated worksheets that include exam questions that can be set as homework. There is a lot of key terminology associated with this topic and time is taken to ensure that students understand the meaning of each of these terms before moving forwards. Students are introduced to the different types of solutions and then a step-by-step guide is used to show them how to compare the water potential of the solution and the cell and then how this will determine which was water moves. The main task is differentiated so that students are challenged and can access the work. This lesson has been designed for GCSE students (14 - 16 year olds in the UK) but is also suitable for A-level students

A fully-resourced lesson which looks at the structures of arteries, veins and capillaries and ensures that students can relate these features to their respective functions. The lesson includes an engaging lesson presentation (41 slides) and a differentiated worksheet The lesson begins by getting the students to come up with a really simple rule to remind themselves that arteries carry blood away from the heart. They are then challenged to extend this definition by considering the pressure of the blood found in arteries. Students will learn that most arteries carry oxygenated blood but will consider and recall the artery which is the exception to the rule. Students are shown a diagram of the basic structure of the artery and the reasons for the narrow lumen and thick muscular wall are explained. Moving forwards, students are challenged to use the work on arteries to sketch a diagram of a vein and to explain why they have given this vessel certain features. A quick competition is then used to check their understand of the work so far whilst introducing valves and again they are given a chance to work out which blood vessel would need these structures in their lumen. The remainder of the lesson focuses on the capillary and time is taken to relate the features to an actual example involving the alveoli of the lungs. There are regular progress checks throughout the lesson to allow the students to check on their understanding. As always, the lesson finishes with a slide containing advanced terminology so that students who have aspirations to take A-level Biology can extend and deepen their knowledge

A resourced lesson which looks at three of the main components of blood and ensures that students can relate their features to their function. The lesson includes an engaging lesson presentation (31 slides) and an associated worksheet The lesson begins by challenging the students to recognise blood from a description of some of its contents. This will enable students to identify some of the substances like hormones and urea that are carried in the plasma. Moving forwards, the rest of the lesson takes a format where the students have to act as recruitment consultants. They have been given 3 job roles to fill and once they have decided on the right candidates for the job, they need to be able to explain why these have been chosen. Students will go study the red and white blood cells and platelets, focusing on how their different specialised features enable them to effectively carry out their respective functions. Students will be able to compare the cells in terms of size, number of nuclei and ultimately explain why they have their features. There are regular progress checks throughout the lesson to allow the students to check on their understanding. This lesson has been designed for GCSE students but is perfectly suitable to be used with KS3 students who are studying the circulatory system

A resourced lesson which looks at the chemical reaction that is aerobic respiration and ensures that students can apply their knowledge to application questions which challenge them to make links to related topics. The lesson includes an engaging lesson presentation (27 slides) and an associated worksheet containing questions. The lesson begins by challenging the students to recognise a definition for breathing and a definition for respiration. This is aimed at helping them to understand that these are different processes as this is a common misconception made by students. Moving forwards, key details about aerobic respiration are introduced to the students through a range of tasks which include competitions to maintain engagement. Time is taken to ensure that students become familiar with ATP and understand that this is the energy store which will be broken down to release energy for the activities that occur in a living organism. The remainder of the lesson challenges the students to take their new found knowledge of aerobic respiration and apply it to range of unfamiliar situations such as explaining why a root hair cell would have such a large number of mitochondria. There are regular progress checks throughout the lesson to allow the students to check on their understanding. As always, the lesson finishes with a slide containing advanced terminology so that students who have aspirations to take A-level Biology can extend and deepen their knowledge

This concise lesson has been designed to cover the content found in specification point 4.1.3.2 (Osmosis) of topic 1 of the AQA GCSE Biology & Combined Science specifications. This resource contains an engaging PowerPoint (23 slides) and accompanying worksheets, some of which have been differentiated to help students of different abilities to take on the task at hand. The lesson begins with the introduction of the term, osmosis, and then students are challenged to use their knowledge of diffusion to write a definition for this method of movement of water molecules. A series of questions which check understanding are included at this early point of the lesson to ensure that the key points are known and any misconceptions are quickly addressed. Students are also challenged with an application question as these can often cause them the most problems. Moving forwards, the rest of the lesson focuses on an osmosis investigation. Scientific skills are tested during a range of tasks as well as numerical skills and guidance is given on how to calculate percentage change. As stated at the top, this lesson has been designed for GCSE-aged students who are studying the AQA GCSE Biology course, but can be used with younger students who are keen to learn about osmosis

This lesson has been designed to cover the content of specification point 4.1.2.1 (Chromosomes) and 4.1.2.2 (Mitosis and the cell cycle) of the AQA GCSE Biology and Combined Science course. Cell division is a topic which can cause students a number of problems so this lesson has been designed to ensure that the key details are covered and checked constantly. As well as the understanding and previous knowledge checks, quiz competitions are written into the lesson to maintain engagement and motivation. The lesson begins with the introduction of the term cell cycle and students will learn that the cycle consists of three stages. The key details of each of these stages is covered during the main part of the lesson so that students can meet the specification requirements of being able to describe the main events. Time is allotted for discussion to encourage students to converse about important points such as what happens to the replicated chromosomes during mitosis to enable identical daughter cells to be produced. Opportunities are taken to make links to other topics such as animal and plant cells as students are challenged to recall the functions of some sub-cellular structures. The final part of the lesson involves a series of summary questions which challenges the students to not only recall content but also to apply to unfamiliar organisms and it is not until the final question that they will answer a question about the cell cycle in humans.

This fully-resourced lesson has been designed to cover both the foundation and higher tier content of specification point 5.3.2 (Control of blood glucose concentration) as found in topic 5 of the AQA GCSE Biology & Combined Science specifications. This resource contains an engaging PowerPoint (37 slides) and accompanying worksheets, some of which have been differentiated so that students of different abilities can access the work. The resource is filled with a wide range of activities, each of which has been designed to engage and motivate the students whilst ensuring that the key Biological content is covered in detail. Understanding checks are included throughout so that the students can assess their grasp of the content. In addition, previous knowledge checks make links to content from earlier topics such as the endocrine system and literacy checks ensure that the students can spell and recognise the key words, which is extremely important considering how many terms begin with the letter g in this homeostatic control system. The following content is covered in this lesson: The receptors, coordination centre and effectors in the control of blood glucose concentration The release of insulin when high blood glucose levels are detected The conversion of glucose to glycogen for storage in liver and muscle cells The causes and treatments of diabetes type I and II The release of glucagon when low blood glucose levels are detected The interaction of insulin and glucagon in a negative feedback cycle As stated at the top, this lesson has been designed for GCSE-aged students who are studying the AQA GCSE Biology or Combined Science courses, but it can be used with A-level students who need to go back over the key points before looking at the homeostatic control in more detail

This lesson has been designed to cover the content as detailed in point 5.2.1 (The structure and function of the human nervous system) of the AQA GCSE Biology & Combined Science specifications. Consisting of a detailed and engaging PowerPoint (38 slides) and accompanying worksheets, the range of activities will motivate the students whilst ensuring that the content is covered in detail. Students will learn how receptors, sensory neurones, the CNS, motor neurones and effectors are involved in the detection and response to a stimulus. Reflex reactions are also considered and discussed so that students can recognise how these automatic and rapid responses avoid damage and pain to humans. Progress checks are included throughout the lesson so that students can assess their understanding of the content and any misconceptions can be addressed whilst quiz competitions, like FROM NUMBERS 2 LETTERS and YOU DO THE MATH, are used to introduce new terms and important values in a fun and memorable way. This lesson has been written for GCSE-aged students who are studying the AQA GCSE Biology or Combined Science specifications but can be used with older students who need to know the key details of the nervous system for their A level course before taking it to greater depths

This resource, which consists of an engaging and detailed PowerPoint and a differentiated worksheet, has been designed to cover the content in the supplement section of topic 14.4 in the CIE IGCSE Biology specification, specifically the control of blood glucose concentration and the symptoms and treatment of diabetes type I. A wide range of activities are found across the lesson which will engage and motivate the students whilst the important content is covered and understanding and previous knowledge checks are included at regular points so students can assess their progress. The following content is covered across this resource: The release of insulin by the pancreas when high glucose levels are detected The role of the liver and muscle cells in the conversion of glucose to glycogen Negative feedback in this homeostatic control mechanism Diagnosis and treatment of type I diabetes Type I diabetes as an autoimmune disease (link to topic 10) The release of glucagon and the role of the liver cells when blood glucose concentration is low As shown above, links are made to other topics where possible so students can recognise the importance of making connections between related subjects. This lesson has been designed for students studying on the CIE IGCSE Biology course but is suitable for older students who are looking at this topic at A-level and need to recall the key details

This resource has been designed to cover the higher tier content of specification point 7.8 as detailed in the Edexcel GCSE Biology & Combined Science specifications. The lesson takes the format of a day at a fertility clinic and students will see how three couples, who are at different stages of their currently unsuccessful journey to getting pregnant, are advised and the treatments that could be on offer to them. Discussion points are included throughout the lesson to encourage the students to talk about the Biology and to allow any misconceptions to be addressed if and when they arise. In addition, previous knowledge checks are regular so that the links between this topic and earlier ones such as the hormones in the menstrual cycle and contraception can be made. Students will be introduced to the abbreviation ART before learning how clomifene is used to treat infertility in women do not ovulate. Time is taken to explore alternative fertility drugs and students are challenged to explain why FSH and LH would be the reproductive hormones contained in these substances. The main focus of the lesson is IVF treatment and the main task culminates with students gaining a number of key points in the for and against argument before being challenged to continue this as a set homework in the form of an evaluation. Quiz competitions are used to introduce key terms in a fun and memorable way and the final task is a mathematical skills check where students will be able to compare the high number of multiple births that are associated with this treatment as compared to the number from natural births. This lesson has been designed for students studying the Edexcel GCSE Biology or Combined Science course but is also suitable for older students who are looking at this topic

This is a fully-resourced lesson consisting of an engaging PowerPoint and differentiated worksheets which have been designed to cover the content of points 7.15 & 7.16 as detailed on the Edexcel GCSE Biology & Combined Science specifications. This point states that students should be able to describe the cause of diabetes type I and II and describe how they are both controlled. There are links made throughout the lesson between this topic and the control of blood glucose concentration from specification point 7,13 and 7.14 The lesson has been designed to take the format of a diabetic clinic where the students perform the duties of the attending doctor. They will move through the different expectations of the role which includes identifying symptoms, diagnosis of type I or II and communication with the patients to reveal the findings. The wide range of activities will enable the students to learn how to spot that someone is suffering from diabetes and the similarities and differences between the different types so they can determine which one is being presented. The summary tasks challenge the students to construct a letter to a patient who is suffering from type II and to identify the correct type from another doctor’s letter. Understanding and previous knowledge checks are interspersed with quiz competitions, like the one shown in the cover image, which make the learning fun and memorable and enable the students to assess their progress. This lesson has been designed for students studying the Edexcel GCSE Biology or Combined Science course but is suitable for both younger and older students who are focusing on this disease