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A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.

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A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
Translation (AQA A-level Biology)
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Translation (AQA A-level Biology)

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This detailed lesson describes the role of the mRNA, tRNA, amino acids and the ribosome during the second stage of protein synthesis - translation. Both the PowerPoint and accompanying resources have been designed to cover the third part of point 4.2 of the AQA A-level Biology specification and ties in with the previous lessons in this topic on RNA and transcription. Translation is a topic which is often poorly understood and so this lesson has been written to enable the students to understand how to answer the different types of questions by knowing and including the key details of the structures involved. The lesson begins by challenging the students to consider why it is so important that the amino acids are assembled in the correct order during the formation of the chain. Moving forwards, a quick quiz round called “LOST IN TRANSLATION” is used to check on their prior knowledge of the mRNA strand, the tRNA molecules, the genetic code and the ribosomes. The next task involves a very detailed description of translation that has been divided into 14 statements which the students have to put into the correct order. By giving them a passage that consists of this considerable detail, they can pick out the important parts to use in the next task where they have to answer shorter questions worth between 3 and 4 marks. These types of questions are common in the assessments and by building up through the lesson, their confidence to answer this type should increase. The final two tasks of the lesson involve another quiz, where the teams compete to transcribe and translate in the quickest time before using all that they have learnt to answer some questions which involve the genetic code and the mRNA codon table.
Transformed host cells (AQA A-level Biology)
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Transformed host cells (AQA A-level Biology)

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This detailed and engaging lesson looks at the culture of transformed host cells as an in vivo method to amplify DNA fragments. Both the PowerPoint and accompanying resources have been designed to cover the third part of point 8.4.1 of the AQA A-level Biology specification and ties in with the previous two lessons in this sub-topic on producing DNA fragments and the polymerase chain reaction. The lesson begins with the introduction of the terms transgenic and transformed. Students will learn that bacterial cells are the most commonly transformed cells so the next task challenges their recall of the structures of these cells so that plasmid DNA can be examined from that point onwards. A quick quiz competition is used to introduce the key term, vector, and then the rest of the lesson looks at the details of the five steps involved in the transformation of the host cell: Remove and prepare the plasmid to act as a vector Insert the DNA fragment into the vector Transfer the recombinant plasmid into the host cell Identify the cells which have taken up the recombinant plasmid All the transformed host cells to replicate and express the novel gene Time is taken to explore the finer details of each step such as the addition of the promoter and terminator regions, use of the same restriction enzyme to cut the plasmid as was used to cut the gene and the different types of marker genes. Links are continuously made to the previous lessons in this topic so that students feel confident to answer assessment questions which bring in knowledge from all of the sections.
Unit 2 B3: Blood flow through the heart (Pearson BTEC Sport & Exercise Science)
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Unit 2 B3: Blood flow through the heart (Pearson BTEC Sport & Exercise Science)

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This lesson describes and explains how the contraction of the heart chambers during atrial and ventricular systole and the relaxation during diastole causes blood to flow through the heart. The engaging PowerPoint and accompanying resource have been designed to cover the first part of point B3 of UNIT 2 of the Pearson BTEC Level 3 National Diploma in Sport and Exercise Science specification. The students will have already encountered aspects of the cardiac cycle in unit 1 and this lesson aims to build on that knowledge. Students will be reminded that the sequence of events known as the cardiac cycle can be split into three parts, which are atrial systole, ventricular systole and diastole. There is a particular focus on the role of the AV and semi-lunar valves in the control of blood flow and students are challenged to explain how pressure changes cause these valves to open or close. The final task of the lesson involves a quiz round called “RECYCLE THIS?” where the teams have to use their knowledge of the cardiac cycle and the function and anatomy of the heart and blood vessels from a previous lesson to spot any errors in the description of blood flow through the heart This lesson has been specifically designed to tie in with the next lesson outlined in the specification on the neural control of the cardiac cycle
Unit 2 B1: Location and anatomy of blood vessels (Pearson BTEC S & ES)
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Unit 2 B1: Location and anatomy of blood vessels (Pearson BTEC S & ES)

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This detailed lesson describes how the anatomy and location of the arteries, arterioles, capillaries, venules and veins enables them to perform their functions. The engaging PowerPoint and accompanying resource have both been designed to cover the 2nd part of point B1 in UNIT 2 of the Pearson BTEC Level 3 National Diploma in Sport and Exercise Science specification. The aorta, vena cava, pulmonary artery and pulmonary vein were covered in the previous lesson on the function and anatomy of the heart so this lesson focuses on the location and anatomy of the 5 different types of blood vessels. Students will have met arteries, veins and capillaries at GCSE so this lesson builds on that knowledge whilst introducing the arterioles and venules. Time is taken to look at the structure of the artery and specifically at how the narrow lumen and thick wall allows this blood vessel to maintain the high pressure of blood and also withstand it. The importance of the arterioles for decreasing this pressure is explained and then students will discuss how the location of capillaries next to tissues allows for a fast rate of diffusion. The rest of the lesson describes how venules connect capillaries to a vein and the structure of this final blood vessel is compared against arteries, where students have to explain why it has a wider lumen with valves and a thinner wall. A series of quiz rounds are used to maintain engagement whilst introducing key terms and values.
Structure of blood vessels (Edexcel A-level PE)
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Structure of blood vessels (Edexcel A-level PE)

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This detailed lesson describes how the structure of the arteries, veins and capillaries enables these blood vessels to perform their functions. The engaging PowerPoint and accompanying resource have both been designed to cover the 3rd part of point 1.2.5 as detailed in the Edexcel A-level PE specification. The aorta, vena cava, pulmonary artery and pulmonary vein were covered in a previous lesson on the structure of the heart so this lesson focuses on the location and structure of these 3 different types of blood vessels. Students will have met arteries, veins and capillaries at GCSE so this lesson builds on that knowledge whilst also introducing the arterioles and venules to deepen their understanding. Time is taken to look at the structure of the artery and specifically at how the narrow lumen and thick wall allows this blood vessel to maintain the high pressure of blood and also withstand it. Students will learn that arterioles are involved in the redistribution of blood and then are challenged to describe and explain when blood would be shunted away from the kidney. Moving forwards, the students are encouraged to discuss how the location of capillaries next to tissues enables a fast rate of diffusion. The rest of the lesson describes how venules connect capillaries to a vein and the structure of this final blood vessel is compared against arteries, where students have to explain a vein has a wider lumen with valves and a thinner wall. A series of quiz rounds are used throughout the lesson to maintain engagement whilst introducing key terms and values.
Bohr shift (AQA A-level PE)
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Bohr shift (AQA A-level PE)

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This fully-resourced lesson explains how a shift of the oxyhaemoglobin dissociation curve is a beneficial phenomenon for exercising individuals. Both the detailed PowerPoint and accompanying resources have been designed to cover the 2nd part of the transportation of oxygen section as detailed in the Applied Anatomy and physiology unit of the AQA A-level PE specification. The previous lesson introduced the transportation of oxygen by haemoglobin and the oxyhaemoglobin dissociation curve so this lesson has been written to build on that knowledge and this is immediately checked at the start of the lesson by getting the students to recall key terms as well as the shape of the curve. A quick quiz competition, called SPORTS SCIENCE, is used to challenge their knowledge of the names of famous sports people to identify the surname of the scientist, Christian Bohr. They are told that this effect describes how an increase in the concentration of a substance affects the dissociation curve and are encouraged to predict what this substance might be. By shifting the curve to the right, students will learn that the affinity of haemoglobin is reduced. The curve is used to show how the saturation of haemoglobin is less at low partial pressures of oxygen when there is increased carbon dioxide concentration before they are challenged to summarise the effect on the dissociation before applying all of their knowledge to a final sporting situation. The final task has been differentiated 2 ways so that students of differing abilities are able to access the work
Glycolytic energy system (OCR A-level PE)
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Glycolytic energy system (OCR A-level PE)

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This fully-resourced lesson describes the specific stages of the glycolytic energy system and explains its role in ATP production for exercise. Both the PowerPoint and accompanying resources have been designed to cover the content of the “Energy systems and ATP resynthesis” section of the OCR A-level PE specification so that students know the type of reaction, fuel used, site of the reaction and ATP yield. The lesson begins by challenging the students to explain which out of stored ATP, phosphocreatine and glycogen in a muscle would be depleted after 10 seconds of intense exercise. This introduces glycogen as the starting substance in the glycolytic system and students will use their prior knowledge to recognise that the 1st step in this system involves the breakdown of glycogen to glucose. The main part of the lesson focuses on glycolysis and the key details of this step are discussed and explained, such as the net yield of ATP. Moving forwards, the students will learn how the product of glycolysis, pyruvate, is converted to lactate but does not result in the formation of any more ATP and this small yield of just 2 ATP means that this system is quickly fatigued. The lesson finishes by covering the duration of exercise that can be supported by the glycolytic system as the dominant energy provider. This lesson has been specifically written to tie in with the next lesson on the aerobic system as well as making links to a previous lesson on the ATP-PC system.
Structure of nucleotides (CIE International A-level Biology)
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Structure of nucleotides (CIE International A-level Biology)

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This detailed lesson describes the structure of a nucleotide including the structure of the phosphorylated nucleotide, ATP. The engaging PowerPoint has been designed to cover point (a) of topic 6.1 as detailed in the CIE International A-level Biology specification and links are made throughout to earlier topics such as biological molecules as well as to upcoming topics like DNA structure and replication. Students were introduced to the term monomer and nucleotide in topic 2, so the start of the lesson challenges them to recognise this latter term when only the letters U, C and T are shown. This has been designed to initiate conversations about why only these letters were used so that the nitrogenous bases can be discussed later in greater detail. Moving forwards, students will learn that a nucleotide is the monomer to a polynucleotide and that deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are two examples of this type of polymer. The main part of the lesson has been filled with various tasks that explore the structural similarities and structural differences between DNA and RNA. This begins by describing the structure of a nucleotide as a phosphate group, a pentose sugar and a nitrogenous base. Time is taken to consider the details of each of these three components which includes the role of the phosphate group in the formation of a phosphodiester bond between adjacent nucleotides on the strand. At this point students are challenged on their understanding of condensation reactions and have to identify how the hydroxyl group associated with carbon 3 is involved along with the hydroxyl group of the phosphoric acid molecule. A number of quiz rounds are used during this lesson, as a way to introduce key terms in a fun and memorable way. One of these rounds introduces adenine and guanine as the purine bases and thymine, cytosine and uracil as the pyrimidine bases and the students are shown that their differing ring structures can be used to distinguish between them. The remainder of the lesson focuses on ATP as a phosphorylated nucleotide and links are made to the hydrolysis of this molecule for energy driven reactions in cells such as active transport
Disaccharides (AQA A-level Biology)
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Disaccharides (AQA A-level Biology)

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Disaccharides are formed from the condensation of two monosaccharides and this lesson describes the formation of maltose, sucrose and lactose. The PowerPoint and accompanying question sheet have been designed to cover the second part of point 1.2 of the AQA A-level Biology specification but also make links to the previous lesson on monosaccharides when considering the different components of these three disaccharides. The first section of the lesson focuses on a prefix and a suffix so that the students can recognise that the names of the common disaccharides end in -ose. In line with this, a quick quiz round is used to introduce maltose, sucrose and lactose before students are challenged on their prior knowledge as they have to describe how condensation reactions and the formation of glycosidic bonds were involved in the synthesis of each one. The main task of the lesson again challenges the students to recall details of a previous lesson as they have to identify the monomers of each disaccharide when presented with the displayed formula. Time is taken to show how their knowledge of these simple sugars will be important in later topics such as digestion, translocation in the phloem and the Lac Operon in the control of gene expression. The lesson finishes with two exam-style questions where students have to demonstrate and apply their newly acquired knowledge
Nucleotides, DNA & RNA (Edexcel A-level Biology A)
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Nucleotides, DNA & RNA (Edexcel A-level Biology A)

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This detailed and engaging lesson describes the basic structure of a mononucleotide and the similarities and differences between DNA and RNA. The PowerPoint and accompanying worksheet containing exam-style questions have been designed to cover points 2.5 (i) & (ii) of the Pearson Edexcel A-level Biology A specification. In topic 1, the students were introduced to a number of monomers and the start of the lesson challenges them to recognise the key term nucleotide when only the letters U, C and T are shown. The next part of the lesson describes the structure of a DNA nucleotide and an RNA nucleotide so that the pentose sugar and the bases adenine, cytosine and guanine can be recognised as similarities whilst deoxyribose and ribose and thymine and uracil are seen as the differences. Time is taken to discuss how a phosphodiester bond is formed between adjacent nucleotides and their prior knowledge and understanding of condensation reactions is tested through a series of questions. Students are then introduced to the purine and pyrimidine bases and this leads into the description of the double-helical structure of DNA and the hydrogen bonds between complementary bases. The final section of the lesson describes the structure of mRNA, tRNA and rRNA and students are challenged to explain why this single stranded polynucleotide is shorter than DNA In addition to the current understanding and prior knowledge checks, a number of quiz rounds have been written into the lesson to introduce key terms in a fun and memorable way and the final round acts as a final check on the structures of DNA and RNA.
Triglycerides (OCR A-level Biology)
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Triglycerides (OCR A-level Biology)

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This fully-resourced lesson describes the relationship between the structure, properties and functions of triglycerides in living organisms. The engaging PowerPoint and accompanying worksheets have been designed to be the first lesson in a series of two that cover specification points 2.1.2 (h), (i) & (j) of the OCR A-level Biology A course and the lesson contains numerous references to relevant future topics such as the importance of the myelin sheath for the conduction of an electrical impulse. The lesson begins with a focus on the basic structure and roles of lipids, including the elements that are found in this biological molecule and some of the places in living organisms where they are found. Moving forwards, the students are challenged to recall the structure of the carbohydrates from earlier in the sub-module so that the structure of a triglyceride can be introduced. Students will learn that this macromolecule is formed from one glycerol molecule and three fatty acids and have to use their understanding of condensation reactions to draw the final structure. Time is taken to look at the difference in structure and properties of saturated and unsaturated fatty acids and students will be able to identify one from the other when presented with a molecular formula. The final part of the lesson explores how the various properties of a triglyceride mean that it has numerous roles in organisms including that of an energy store and source and as an insulator of heat and electricity.
Module 2.1.2: Biological molecules (OCR A-level Biology A)
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Module 2.1.2: Biological molecules (OCR A-level Biology A)

13 Resources
The biological molecules sub-module is incredibly important, not just because it is found near to the start of the course, but also because of its detailed content which must be well understood to promote success with most of the other OCR A-level Biology A modules. Many hours of intricate planning have gone into the design of all of the 13 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions. The following specification points are covered by the lessons within this bundle: The relationship between the properties of water and its roles for living organisms The concept of monomers and polymers and the importance of condensation and hydrolysis reactions The chemical elements that make up biological molecules The ring structure and properties of glucose and structure of ribose The synthesis and breakdown of a disaccharide and a polysaccharide The relationship between the structures, properties and functions of starch, glycogen and cellulose The structure of a triglyceride and a phospholipid as macromolecules The synthesis and breakdown of triglycerides The relationship between the properties and functions of triglycerides, phospholipids and cholesterol The general structure of an amino acid The synthesis and breakdown of dipeptides and polypeptides The levels of protein structure The structure and function of globular proteins The properties and functions of fibrous proteins The key inorganic ions that are involved in biological processes How to carry out and interpret the results of the chemical tests for proteins, reducing and non-reducing sugars, starch and lipids Due to the detail of each of these lessons, it is estimated that it will take in excess of 6 weeks of allocated teaching time to cover the content. If you would like to see the quality of the lessons, download the properties of water, glucose & ribose, amino acids and dipeptides and polypeptides lessons as these have been shared for free
Topic 2: Biological molecules (CIE International A-level Biology)
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Topic 2: Biological molecules (CIE International A-level Biology)

11 Resources
The biological molecules topic is incredibly important, not just because it is found near to the start of the course, but also because of its detailed content which must be well understood to promote success with the other 18 CIE International A-level Biology topics. Many hours of intricate planning have gone into the design of all of the 11 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions. The following specification points are covered by the lessons within this bundle: Tests for reducing and non-reducing sugars The iodine test for starch The emulsion test for lipids The biuret test for proteins The ring forms of alpha and beta glucose The meaning of the terms monomer, polymer, macromolecule, monosaccharide, disaccharide and polysaccharide The formation of a glycosidic bond by a condensation reaction The breakage of glycosidic bonds by hydrolysis reactions The relationship between the molecular structure and functions of a triglyceride The relationship between the structure and functions of a phospholipid The structure of an amino acid and the formation and breakage of a peptide bond The meaning of the different protein structures and the types of bonding that hold these molecules in shape The molecular structure of haemoglobin and collagen as examples of globular and fibrous proteins The relationship between the properties and roles of water in living organisms The lesson on the biuret test for proteins and the emulsion test for lipids also contains a section which can be used for the revision of topics 2.2 and 2.3 Due to the detail of each of these lessons, it is estimated that it will take in excess of 4 weeks of allocated teaching time to cover the content. If you would like to see the quality of the lessons, download the alpha and beta glucose, phospholipids and haemoglobin and collagen lessons as these have been shared for free
Simple & facilitated diffusion (Edexcel A-level Biology A)
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Simple & facilitated diffusion (Edexcel A-level Biology A)

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Simple and facilitated diffusion are forms of passive transport and this lesson describes the factors that increase the rate of this movement across membranes. This fully-resourced lesson is the first in a series of two that have been designed to cover specification point 2.4 of the Pearson Edexcel A-level Biology A and the involvement of channel and carrier proteins is also described and discussed. In a number of previous lessons that covered specification points 2.1 and 2.2, students were provided with the details of gas exchange surfaces and the structure and properties of cell membranes. This lesson continually refers back to the content of these lessons so that links can be made between the movement across a cell membrane with the concentration gradient, the parts of the membrane involved and any features that may increase the rate at which the molecules move. A series of questions about the alveoli is used to demonstrate how a large surface area, a short diffusion distance and the maintenance of a steep concentration gradient will increase the rate of simple diffusion. One of two quick quiz rounds is then used to introduce temperature and size of molecule as two further factors that can affect simple diffusion. The remainder of the lesson focuses on facilitated diffusion and describes how transmembrane proteins are needed to move small, polar or large molecules from a high concentration to a lower concentration across a partially permeable membrane. The other lesson included in this series to cover specification point 2.4 describes active transport, endocytosis and exocytosis.
Amplifying DNA using the PCR (Edexcel A-level Biology A)
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Amplifying DNA using the PCR (Edexcel A-level Biology A)

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This lesson describes how the polymerase chain reaction (PCR) is used to amplify DNA. The concise PowerPoint has been primarily designed to cover the detail of specification point 6.4 of the Pearson Edexcel A-level Biology A specification but also makes continual links to the previous lesson on DNA profiling where the PCR is important as well as DNA structure. A quick quiz competition is used to introduce the PCR abbreviation before students are encouraged to discuss with the aim of identifying the enzyme involved and to recall the action of this enzyme as covered in DNA replication in topic 2. Students will learn that this reaction involves cyclical heating and cooling to a range of temperatures so another quiz is used to introduce these values. The main part of the lesson describes the main steps in the PCR and the reasons for each temperature is discussed and explained. Links are constantly made to related topics such as DNA structure are students are challenged on their understanding through exam-style questions. Time is taken to examine the key points in detail, such as the fact that the DNA polymerase used is taken from an extremophile so that it is not denatured at the high temperature.
Structure of prokaryotic cells (AQA A-level Biology)
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Structure of prokaryotic cells (AQA A-level Biology)

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This detailed lesson describes how the structure of a prokaryotic cell differs from the structure of an eukaryotic cell. The engaging PowerPoint and accompanying resources have been designed to cover the first part of point 2.1.2 of the AQA A-level Biology specification and describes how the size and cell structures differ and also covers the additional features that are found in some prokaryotic cells. A clear understanding of terminology is important for A-level Biology so this lesson begins with a challenge, where the students have to add an additional prefix to their prefix and suffix table which they believe will translate as before or in front of. This leads into the discovery of the meaning of prokaryote as before nucleus and this acts to remind students that these types of cell lack this cell structure. Links to the previous lessons on the eukaryotic cells are made throughout the lesson and at this particular point, the students are asked to work out why the DNA would be described as naked and to state where it will be found in the cell. Moving forwards, the students will discover that these cells also lack membrane bound organelles and a quick quiz competition challenges them to identify the specific structure that is absent from just a single word. In addition to the naked DNA, students will learn that there are also ribosomes in the cytoplasm and will discover that these are smaller than those found in the cytoplasm of an eukaryotic cell (but the same size as those in chloroplasts and mitochondria). The remainder of the lesson focuses on the composition of the cell wall, the additional features of prokaryotic cells such as plasmids and there is also the introduction of binary fission as the mechanism by which these organisms reproduce.
Fluid mosaic membrane (CIE International A-level Biology)
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Fluid mosaic membrane (CIE International A-level Biology)

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This detailed lesson describes the fluid mosaic model of membrane structure and outlines the roles of the different components . Fully resourced, the PowerPoint and accompanying worksheets have been designed to cover specification point 4.1 (a) of the CIE International A-level Biology specification but as the membranes and target cells are discussed, points 4.1 (b) and © are also partially covered The fluid mosaic model is introduced at the start of the lesson so that it can be referenced at appropriate points throughout the lesson. Students were introduced to phospholipids in topic 2 and so an initial task challenges them to spot the errors in a passage describing the structure and properties of this molecule. This reminds them of the bilayer arrangement, with the hydrophilic phosphate heads protruding outwards into the aqueous solutions on the inside and the outside of the cell. In a link to some upcoming lessons on the transport mechanisms, the students will learn that only small, non-polar molecules can move by simple diffusion and that this is through the tails of the bilayer. This introduces the need for transmembrane proteins to allow large or polar molecules to move into the cell by facilitated diffusion and active transport. Proteins that act as receptors as also introduced and an opportunity is taken to make a link to an upcoming topic so that students can understand how hormones or drugs will bind to target cells in this way. Moving forwards, the structure of cholesterol is covered and students will learn that this hydrophobic molecule sits in the middle of the tails and therefore acts to regulate membrane fluidity. The final part of the lesson challenges the students to apply their newly-acquired knowledge to a series of questions where they have to explain why proteins may have moved when two cells are used and to suggest why there is a larger proportion of these proteins in the inner mitochondrial membrane than the outer membrane.
The significance of water (Edexcel A-level Biology B)
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The significance of water (Edexcel A-level Biology B)

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This detailed lesson describes the importance of the dipole nature of water and its numerous properties to living organisms. The engaging PowerPoint and accompanying resource have been designed to cover the details of specification point 1.7 of the Edexcel A-level Biology B course and the intricate planning ensures that each role is illustrated using a specific example. As the final lesson in the biological molecules topic, not only does this lesson cover the important content related to water but also acts as a revision tool as it checks on key topic 1 content such as condensation and hydrolysis reactions. A wide range of tasks are used to check on current understanding and prior knowledge and quick quiz competitions introduce key terms and values in a memorable way. The start of the lesson considers the structure of water molecules, focusing on the covalent and hydrogen bonds, and the dipole nature of this molecule. Time is taken to emphasise the importance of these bonds and this property for the numerous roles of water and then over the remainder of the lesson, the following properties are described and discussed and linked to real-life examples: high specific heat capacity polar solvent surface tension incompressibility maximum density at 4 degrees Celsius
Formation of polypeptides & protein structures (Edexcel A-level Biology B)
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Formation of polypeptides & protein structures (Edexcel A-level Biology B)

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This lesson describes the formation of dipeptides & polypeptides and the different levels of protein structure. Both the engaging PowerPoint and accompanying resources have been designed to cover specification points 1.3 (ii), (iii) & (iv) of the Edexcel A-level Biology B specification and also makes continual links to previous lessons such as amino acids as well as to upcoming lessons like antibodies and enzymes so students can understand where proteins are involved. The start of the lesson focuses on the formation of a peptide bond during a condensation reaction so that students can understand how a dipeptide is formed and therefore how a polypeptide forms when multiple reactions occur. The main part of the lesson describes the different levels of protein structure. A step by step guide is used to demonstrate how the sequences of bases in a gene acts as a template to form a sequence of codons on a mRNA strand and how this is translated into a particular sequence of amino acids known as the primary structure. The students are then challenged to apply their understanding of this process by using three more gene sequences to work out three primary structures and recognise how different genes lead to different sequences. Moving forwards, students will learn how the order of amino acids in the primary structure determines the shape of the protein molecule, through its secondary, tertiary and quaternary structure and time is taken to consider the details of each of these. There is a particular focus on the different bonds that hold the 3D shape firmly in place and a quick quiz round then introduces the importance of this shape as exemplified by enzymes, antibodies and hormones. Students will see the differences between globular and fibrous protein and again biological examples are used to increase relevance. The lesson concludes with one final quiz round called STRUC by NUMBERS where the students have to use their understanding of the protein structures to calculate a numerical answer.
Topic 1: Biological molecules (Edexcel A-level Biology B)
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Topic 1: Biological molecules (Edexcel A-level Biology B)

18 Resources
The biological molecules topic is incredibly important, not just because it is found at the start of the course, but also because of its detailed content which must be well understood to promote success with the other 9 Edexcel A-level Biology B topics. Many hours of intricate planning has gone into the design of all of the 18 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions. The following specification points are covered by the lessons within this bundle: The differences between monosaccharides, disaccharides and polysaccharides The structure of glucose and ribose The formation of disaccharides and polysaccharides from monosaccharides The structure of starch, glycogen and cellulose The synthesis of a triglyceride The differences between saturated and unsaturated lipids The relationship between the structure of lipids and their roles The structure and properties of phospholipids The structure of an amino acid The formation of polypeptides and proteins The role of ionic, hydrogen and disulphide bonding in proteins The levels of protein structure The structure of collagen and haemoglobin The structure of DNA The semi-conservative replication of DNA A gene is a sequence of bases on DNA that codes for an amino acid sequence The structure of mRNA The structure of tRNA The process of transcription The process of translation Base deletions, insertions and substitutions as gene mutations The effect of point mutations on amino acid sequences The structure of enzymes as globular proteins The concept of specificity and the induced-fit hypothesis Enzymes are catalysts that reduce activation energy Understand how temperature affects enzyme activity Enzymes catalyse a wide range of intracellular reactions as well as extracellular ones The importance of water for living organisms Due to the detail included in these lessons, it is estimated that it will take in excess of 2 months of allocated A-level teaching time to complete. If you would like to see the quality of the lessons then download the monosaccharides, disaccharides and polysaccharides, glucose and ribose, triglycerides, structure of DNA and transcription lessons as these have been uploaded for free.