This fully-resources lesson looks at the phenomenon known as the Bohr effect and describes and explains how an increased carbon dioxide concentration affects the dissociation of oxyhaemoglobin. The PowerPoint has been designed to cover the second part of point 3.1.2 (j) of the OCR A-level Biology A specification and continually ties in with the previous lesson on the role of haemoglobin. The lesson begins with a terminology check to ensure that the students can use the terms affinity, oxyhaemoglobin and dissociation. In line with this, they are challenged to draw the oxyhaemoglobin dissociation curve and are reminded that this shows how oxygen associates with haemoglobin but how it dissociates at low partial pressures. Moving forwards, a quick quiz is used to introduce Christian Bohr and the students are given some initial details of his described effect. This leads into a series of discussions where the outcome is the understanding that an increased concentration of carbon dioxide decreases the affinity of haemoglobin for oxygen. The students will learn that this reduction in affinity is a result of a decrease in the pH of the cell cytoplasm which alters the tertiary structure of the haemoglobin. Opportunities are taken at this point to challenge students on their prior knowledge of protein structures as well as the bonds in the tertiary structure. The lesson finishes with a series of questions where the understanding and application skills are tested as students have to explain the benefit of the Bohr effect for an exercising individual. These questions are differentiated to allow students of differing abilities to access the work and to be challenged

This is a fully-resourced REVISION lesson which challenges the students on their knowledge of the content in TOPIC B5 (Genetics) of the Edexcel GCSE Combined Science specification. The lesson uses an engaging PowerPoint (63 slides) and accompanying worksheets to motivate students whilst they assess their understanding of this topic. A range of exam questions, quick tasks and quiz competitions are used to test the following sub-topics: Recognising and using genetic terminology in context Constructing genetic diagrams to calculate offspring percentages for diseases caused by dominant and recessive alleles The sex chromosomes and sex determination Meiosis and the formation of haploid daughter cells The structure of DNA Extracting DNA from a fruit Genetic and environmental variation Mutations and their effect on the phenotype The mathematical element of the course is also tested throughout the lesson and students are given helpful hints on exam techniques and how to structure answers. This resource is suitable for use at the end of topic B3 or in the lead up to mocks or the actual GCSE exams.

This revision resource has been written to include a range of activities that motivate the students whilst they assess their understanding of the content found in module 2.1.5 (Biological membranes) of the OCR A-level Biology A specification. The resource includes a detailed and engaging Powerpoint (71 slides) and associated worksheets The range of activities have been designed to cover as much of the content as possible but the following sub-topics have been given particular attention: The movement of molecules by active transport which requires ATP as an immediate source of energy The movement of molecules by passive processes The use of membrane-spanning proteins in facilitated diffusion and active transport Factors that increase the rate of simple diffusion The movement of water across membranes by osmosis The effects that solutions of different water potentials can have on animal and plant cells The fluid mosaic model of membrane structure The roles of the components of the plasma cell membrane In addition to these topics, some topics from other modules such as organelles, synapses and autoimmune diseases are tested in order to challenge the students on their ability to make links between the modules. The range of activities include exam questions and understanding checks as well as quiz competitions to maintain student engagement.

This revision resource includes a range of activities that will act to engage and motivate the students whilst they assess their understanding of the Animal nutrition content (topic B6) of the CIE IGCSE Combined Science specification for examination in June and November 2020 and 2021. There are exam questions with explained answers as well as quick tasks and quiz competitions such as “Have you got the right BALANCE” where students are challenged to recognise whether a statement about the balanced diet is accurate or not. The lesson was designed to cover as much content as possible but the following topics have received particular attention: Mechanical digestion Chemical digestion by digestive enzymes Amylase and the break down of starch The adaptations of the small intestine to allow absorption The roles of the hydrochloric acid in gastric juice The break down of lipids in the small intestine The components of a balanced diet This resource includes a detailed and engaging PowerPoint (51 slides) and a worksheet which is differentiated two ways. Efforts have been made to make links to other topics such as enzymes (B4) so students can see the importance of being able to make connections in their answers

This clear and detailed lesson describes the process of oxidative phosphorylation, including the roles of the electron carriers, oxygen and the mitochondrial cristae and explains the role of chemiosmosis. The PowerPoint has been designed to cover points 5.2.2 (g) and (h) of the OCR A-level Biology A specification and includes details of the electron transport chain, proton gradients and ATP synthase. The lesson begins with a discussion about the starting point of the reaction. In the previous stages, the starting molecule was the final product of the last stage but in this stage, it is the reduced coenzymes which release their hydrogen atoms. Moving forwards, the process of oxidative phosphorylation is covered in 7 detailed steps and at each point, key facts are discussed and explored in further detail to enable a deep understanding to be developed. Students will see how the proton gradient across the inner membrane is created and that the flow of protons down the channel associated with ATP synthase results in a conformational change and the addition of phosphate groups to ADP by oxidative phosphorylation. Understanding checks are included throughout the lesson to enable the students to assess their progress and prior knowledge checks allow them to recognise the clear links to other topics and modules. This lesson has been written to tie in with the other uploaded lessons on glycolysis, the Link reaction and Krebs cycle and anaerobic respiration

An engaging lesson presentation (33 slides) that looks at the key details of asexual reproduction, examines the process in bacteria and plants and also considers the advantages and disadvantages. The lesson begins by challenging the students to discuss whether reproduction always requires two (parents). Students will see how only one parent is involved in this type of reproduction and will focus on how it takes place in bacteria. Moving forwards, students will be introduced to the methods of runners, bulbs and tubers in plants. By making connections to natural selection, students will be challenged to think about the benefits of asexual reproduction. There are regular progress checks throughout the lesson so that students can assess their understanding. This lesson is suitable for both KS3 and GCSE students

An engaging lesson presentation (58 slides) and associated worksheets that uses a combination of exam questions, quick tasks and quiz competitions to help the students to assess their understanding of the topics found within unit B1 of the AQA GCSE Biology specification. The topics that are tested within the lesson include: Eukaryotes and prokaryotes Animal and plant cells Microscopy Chromosomes Diffusion Osmosis Active transport Students will be engaged through the numerous activities including quiz rounds like "A QUESTION of CELLS" and "Take the Hotseat" whilst crucially being able to recognise those areas which need further attention

A fully resourced lesson which includes an informative lesson presentation (25 slides) and an associated worksheet that show students how to give answers to a certain number of significant figures. The answers to questions in Science are often required to be given in significant figures and this lesson guides students through this process, including the rules of rounding that must be applied for success to be likely. This lesson has been designed for GCSE students but is suitable for KS3

An informative lesson presentation (38 slides) that looks at a range of non-communicable diseases and also explores how risk factors can increase the chances of an individual having one of these diseases. The lesson begins by looking at CHD so that students can recognise that this is a non-communicable disease and check on their understanding of this key term. Moving forwards, a step by step question and answer format is used to show students how to form a long answer. Key terminology such as thrombosis and atherosclerosis are introduced using quick quiz competitions which act to maintain the engagement. The rest of the lesson focuses on a range of risk factors for cardiovascular diseases and time is taken to deepen knowledge of the human anatomy by challenging students to link the names of arteries to the organs that they supply. Progress checks have been written into the lesson at regular intervals so that students can constantly assess their understanding and any misconceptions can be addressed. This lesson has been written for GCSE students (14 - 16 year olds in the UK)

A fully-resourced lesson, which has been designed for GCSE students, and includes an engaging and informative lesson presentation (37 slides) and differentiated worksheets. This lesson explores the type of cell division known as meiosis and focuses on the use of key terminology so that students can apply their knowledge to any organism that carries out this division, and not just humans. For this reason, time is taken at the start of the lesson to go over the meaning of the terms, diploid and haploid. Students are also taught how to think about the quantity of DNA inside a cell in terms of n, so that they can see and understand how this quantity changes through the cell cycle. They are encouraged to fill in a table at each stage of the cycle to show the quantity of DNA. In this way, students will understand how a diploid parent cell goes through interphase and as a result of DNA replication, the quantity of DNA is 4n as the first meiosis division is about to start. Although this could be viewed as high end knowledge, the format of this lesson should allow all abilities to understand and therefore have more chance of being successful with meiosis questions. Students are encouraged to think for themselves to work out how many daughter cells will result at the end of two divisions and to consider the quantity of DNA found inside those cells. At this stage of the lesson, students have to summarise all they have learnt into two key points (as shown on the cover image). The remainder of the lesson gives them the opportunity to apply their knowledge with a range of questions and it is not until right at the end that they are allowed to finally relate this cell division to humans. Although this lesson has been primarily designed for GCSE students (14 - 16 year olds in the UK), it is highly suitable for A-level lessons, especially if a teacher wants to recap on this cell division before extending knowledge.

This lesson uses the example of the genetic engineering of bacteria to produce insulin to walk students through the steps involved in this process. It has been written for GCSE students and therefore includes the detail required at this level, such as the involvement of restriction enzymes and the sticky ends that their cut produces. The lesson begins by challenging students to recognise that insulin is being described by a series of clues. Some further details of this hormone are recalled to test their previous knowledge of the endocrine system and also to lead into the genetic engineering of bacteria to make this protein. Moving forwards, time is taken to go through the details of plasmids and how they act as vectors as well as the enzymes, restriction and ligase. The main task of the lesson uses a series of descriptions to go through the steps involved in the process. Words or phrases are missing from each description so students have to use the terms they’ve encountered in this lesson as well as their prior knowledge to complete the step. Discussion-provoking questions are added to encourage the students to consider why certain parts of the process occur. The lesson concludes by the consideration of other organisms which have been genetically engineered as well as some of the risks of the process, which students are asked to complete for homework. As detailed above, this lesson has been designed for GCSE students but could be used with students taking A-level Biology, who are struggling to understand the detail found at this level and need to revisit the foundations.

This is a fully-resourced revision lesson that uses a combination of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content found within Module 5.2.1 (Photosynthesis) of the OCR A-level Biology A specification. The sub-topics and specification points that are tested within the lesson include: The interrelationship between photosynthesis and respiration The structure of a chloroplast The importance of photosynthetic pigments in photosynthesis The light dependent stage of photosynthesis The fixation of carbon dioxide and the light independent stage of photosynthesis Factors affecting photosynthesis Students will be engaged through the numerous quiz rounds such as “Can you DEPEND on your knowledge” and “Photosynthesising the SAFE way” whilst crucially being able to recognise those areas which require their further attention during general revision or during the lead up to the actual A-level terminal exams

This is a fully-resourced REVISION lesson that consists of an engaging PowerPoint (129 slides) and associated worksheets that challenge the students on their knowledge of topics 4 - 6 (Community-level systems, Interaction between systems and Global challenges) of the OCR Gateway A GCSE Combined Science specification and can be assessed on PAPER 2. A wide range of activities have been written into the lesson to maintain motivation and these tasks include exam questions (with answers), understanding checks, differentiated tasks and quiz competitions. The lesson has been designed to include as much which of the content from topic 1, but the following sub-topics have been given particular attention: Identifying bacterial, fungal and viral diseases The steps in the process of genetic engineering Evolution by natural selection The development of antibiotic resistance in bacteria The prevention and reduction of the spread of pathogens Vaccinations The risk factors of CHD Genetic terminology Predicting the results of single-gene crosses Sex determination Ecological terms The carbon cycle The mathematic elements of the Combined Science specification are challenged throughout the resource. Due to the size of this resource, it is likely that it’ll be used over the course of a number of lessons and it is suitable for use as an end of topic revision aid, in the lead up to the mocks or in the lead up to the actual GCSE exams.

This lesson has been designed to cover the content as detailed in point 2.13 (The structure and function of the nervous system) of the Edexcel GCSE Biology & Combined Science specifications. Consisting of a detailed and engaging PowerPoint (38 slides) and accompanying worksheets, the range of activities will motivate the students whilst ensuring that the content is covered in detail. Students will learn how receptors, sensory neurones, the CNS, motor neurones and effectors are involved in the detection and response to a stimulus. There is a focus on the structure of the sensory and motor neurones and the presence of the myelin sheath in both of these neurones is discussed with relation to the increased speed of conduction. Students will understand that a synapses involve the diffusion of neurotransmitters and allow communication between neurones and they are briefly introduced to relay neurones but these are covered in more detail in the reflexes lesson. Progress checks are included throughout the lesson so that students can assess their understanding of the content and any misconceptions can be addressed whilst quiz competitions, like FROM NUMBERS 2 LETTERS and SAY WHAT YOU SEE, are used to introduce new terms in a fun and memorable way. This lesson has been written for GCSE-aged students who are studying the Edexcel GCSE Biology or Combined Science specifications but can be used with older students who need to know the key details of the nervous system for their A level course before taking it to greater depths

This lesson has been designed to cover the higher tier content of specification points 7.4 & 7.5 (The hormones involved in the stages of the menstrual cycle) which is found in topic 7 of the Edexcel GCSE Biology & Combined Science specifications. A wide range of activities will engage and motivate the students whilst the content is covered in detail and understanding checks are included at regular points to enable the students to self-assess their new found knowledge. Students will learn about the different stages of the menstrual cycle including menstruation and ovulation and will see how FSH, oestrogen, LH and progesterone interact to control these stages. This lesson has been designed for GCSE-aged students who are taking the Edexcel GCSE Biology or Combined Science course but it is also suitable for younger students who are looking into this topic as part of the reproduction module