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A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.

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A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
Molecular evidence & evolution (CIE A-level Biology)
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Molecular evidence & evolution (CIE A-level Biology)

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This lesson describes how molecular evidence can be used to reveal similarities between closely-related organisms. The PowerPoint and accompanying resources have been primarily designed to cover point 17.3 (b) of the CIE A-level Biology specification and focus on the comparison of protein structure and mitochondrial DNA but can also be used as a revision of related topics that include protein synthesis and gene mutations. The lesson begins with the introduction of convergent evolution, a process where organisms independently evolve to have similar features due to theeir habitation of similar environments. This allows the importance of molecular evidence to be considered to ensure that organisms which are closely related (in terms of evolution) are recognised. The comparison of the primary structure of a protein involved in respiration (cytochrome c) is used to demonstrate how protein sequence data can be useful. At this point, a series of exam-style questions are used to challenge the students on their knowledge of protein synthesis and gene mutations from topics 6 and 16. The remainder of the lesson considers the use of mitochondrial DNA and a study of the mtDNA genomes of 51 gibbons demonstrates how this can provide evidence of relationships, even in organisms that show high taxonomic diversity like these lesser apes.
Features of the kingdoms (CIE International A-level Biology)
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Features of the kingdoms (CIE International A-level Biology)

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This detailed lesson outlines the characteristics features of the kingdoms Protoctista, Fungi, Plantae and Animalia. The engaging PowerPoint and accompanying resources have been designed to cover point 18.2 [c] of the CIE International A-level Biology specification which states that students should be able to describe the features of these four eukaryotic kingdoms. This lesson begins with a knowledge recall as students have to recognise that prior to 1990, kingdom was the highest taxa in the classification hierarchy. Moving forwards, they will recall the names of the five kingdoms and immediately be challenged to split them so that the prokaryotae kingdom is left on its own. The features of this kingdom are given so that the lesson can focus on the four eukaryotic kingdoms. Students are constantly challenged on their understanding of the current topic as well as that of earlier topics, as demonstrated by a differentiated task about the structure and function of cellulose which was covered in topic 2. This task is found in the section of the lesson where the main constituent of the wall can be used to distinguish between plantae, fungi and prokaryotae. Quick quiz competitions, such as SAY WHAT YOU SEE are used to introduce key terms in a fun and memorable way. The final part of the lesson looks at the protoctista kingdom and students will come to understand how these organisms tend to share a lot of animal or plant-like features.
Interphase, mitosis & cytokinesis (CIE A-level Biology)
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Interphase, mitosis & cytokinesis (CIE A-level Biology)

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This lesson describes the key events that occur during interphase, mitosis and cytokinesis in the eukaryotic cell cycle. The PowerPoint and accompanying resources have been designed to cover point 5.1 [c] of the CIE A-level Biology specification and challenges the students on their knowledge of chromosomes from an earlier lesson as well as preparing them for upcoming lessons on the main stages of mitosis and its significance in life cycles The students were introduced to the cell cycle at GCSE so this lesson has been planned to build on that knowledge and to emphasise that the M phase which includes mitosis (nuclear division) only occupies a small part of the cycle. The students will learn that interphase is the main stage and that this is split into three phases, G1, S and G2. A range of tasks which include exam-style questions, guided discussion points and quick quiz competitions are used to introduce key terms and values and to describe the main processes that occur in a very specific order. There is also a focus on the checkpoints, such as the restriction point that occurs before the S phase to ensure that the cell is ready for DNA replication. Extra time is taken to ensure that key terminology is included and understood, such as sister chromatid and centromere, and this focus helps to show how it is possible for genetically identical daughter cells to be formed at the end of the cycle. Important details of mitosis are introduced so students are ready for the next lesson, before the differences in cytokinesis in animal and plant cells are described.
Sex linkage (Edexcel A-level Biology B)
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Sex linkage (Edexcel A-level Biology B)

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This fully-resourced lesson describes the inheritance of genes that are carried on the X chromosome and includes a particular focus on haemophilia in humans. The detailed PowerPoint and associated differentiated resources have been designed to cover specification point 8.2 (v) as detailed in the Edexcel A-level Biology B specification. Key genetic terminology is used throughout and the lesson begins with a check on their ability to identify the definition of homologous chromosomes. Students will recall that the sex chromosomes are not fully homologous and that the smaller Y chromosome lacks some of the genes that are found on the X. This leads into one of the numerous discussion points, where students are encouraged to consider whether females or males are more likely to suffer from sex-linked diseases and they will be challenged to find evidence to support this decision later in the lesson. In terms of humans, the lesson focuses on haemophilia and red-green colour blindness and a step-by-step guide is used to demonstrate how these specific genetic diagrams should be constructed and how the phenotypes should then be interpreted. The final tasks of the lesson challenge the students to carry out a dihybrid cross that involves a sex-linked disease and an autosomal disease before applying their knowledge to a question about chickens and how the rate of feather production in chicks can be used to determine gender. All of the tasks are differentiated so that students of differing abilities can access the work and all exam questions have fully-explained, visual markschemes to allow them to assess their progress and address any misconceptions
Taxonomic hierarchy and the binomial naming system (OCR A-level Biology)
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Taxonomic hierarchy and the binomial naming system (OCR A-level Biology)

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This lesson covers the biological classification of a species, taxonomic hierarchy and the binomial system of naming species. The engaging PowerPoint and accompanying resources have been designed to cover points 4.2.2 (a) & (b) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply an understanding of these three topics. The lesson begins by looking at the meaning of the term population in Biology so that the term species can be introduced. A hinny, which is the hybrid offspring of a horse and a donkey, is used to explain how these two organisms must be members of different species because they are unable to produce fertile offspring. Moving forwards, students will learn that species is the lowest taxon in the modern-day classification hierarchy. The first of a number of rounds of a competition is used to engage the students whilst they learn the names of the 7 other taxa and the horse and the donkey from the earlier example are used to complete the hierarchy. Students will understand that the binomial naming system was introduced by Carl Linnaeus to provide a universal name for each species and they will be challenged to apply their knowledge by completing a hierarchy for a modern-day human, by spotting the correct name for an unfamiliar organism and finally by suggesting advantages of this system.
Adaptations & natural selection (OCR A-level Biology)
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Adaptations & natural selection (OCR A-level Biology)

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This fully-resourced lesson describes how the mechanism of natural selection results in changes in a population that are known as adaptations. The PowerPoint and accompanying resources have been designed to cover specification points 4.2.2 (g), (h) and (i) as detailed in the OCR A-level Biology A specification and also considers how antibiotic resistance has implications for human populations. President Trump’s error ridden speech about antibiotics is used at the beginning of the lesson to remind students that this is a treatment for bacterial infections and not viruses as he stated. Moving forwards, 2 quick quiz competitions are used to introduce MRSA and then to get the students to recognise that they can use this abbreviation as a reminder to use mutation, reproduce, selection (and survive) and allele in their descriptions of evolution through natural selection. The main task of the lesson challenges the students to form a description that explains how this strain of bacteria developed resistance to methicillin to enable them to see the principles of natural selection. This can then be used when describing how the anatomy of the modern-day giraffe has evolved over time. The concept of convergent evolution is introduced and links are made to the need for modern classification techniques which was considered in the previous sub-module. Moving forwards, students will understand how natural selection leads to adaptations and a quick quiz competition introduces the different types of adaptation and a series of tasks are used to ensure that the students can distinguish between anatomical, behavioural and physiological adaptations. The Marram grass is used to test their understanding further, before a step by step guide describes how the lignified cells prevent a loss of turgidity. Moving forwards, the students are challenged to explain how the other adaptations of this grass help it to survive in its environment. A series of exam-style questions on the Mangrove family will challenge them to make links to other topics such as osmosis and the mark schemes are displayed to allow them to assess their understanding. The final part of the lesson focuses on the adaptations of the anteater and again current understanding of this topic is tested alongside prior knowledge of classification hierarchy. Due to the extensiveness of this lesson and the detail contained within the resources, it is estimated that it will take in excess of 2/3 hours of allocated A-level teaching time to deliver this lesson.
Producing DNA fragments (AQA A-level Biology)
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Producing DNA fragments (AQA A-level Biology)

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This detailed lesson explores how a range of methods are used to produce fragments of DNA as part of the recombinant DNA technology process. Both the engaging PowerPoint and accompanying resources have been written to cover the first part of point 8.4.1 of the AQA A-level Biology specification and also provides information that will prove useful for the other lessons in this sub-topic on the polymerase chain reaction and using transformed host cells. The lesson begins with a definition of recombinant DNA technology so that students can begin to understand how this process involves the transfer of DNA fragments from one species to another. Links are made to the genetic code and transcription and translation mechanisms, which were met in topic 4, in order to explain how the transferred gene can be translated in the transgenic organism. Moving forwards, the method involving reverse transcriptase and DNA polymerase is introduced and their knowledge of the structure of the polynucleotides and the roles of enzymes is challenged through questions and discussion points. Restriction enzymes are then introduced and time is taken to look at the structure of a restriction site as well as the production of sticky ends due to the staggered cut on the DNA. A series of exam-style questions with displayed mark schemes are used to allow the students to assess their current understanding. The final part of the lesson looks at the production of synthetic genes of any sequence using gene machines and a series of application questions are used to push the students to consider how this advance in technology could be utilised. As well as understanding and prior knowledge checks, quick quiz competitions are used throughout the lesson to introduce key terms such as cDNA and EcoR1 in a memorable way.
Energy transfer between trophic levels (Edexcel A-level Biology B)
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Energy transfer between trophic levels (Edexcel A-level Biology B)

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This lesson describes how energy is transferred between trophic levels using the terms net and gross primary productivity and calculates the efficiency of this transfer. The PowerPoint and accompanying resources have been designed to cover points 10.2 (i) and (ii) of the Edexcel A-level Biology B specification and the content of the lesson also accounts for the loss of energy between different levels and describes the farming practices that act to reduce these losses. Due to the fact that the productivity of plants is dependent on photosynthesis, a series of exam-style questions have been written into the lesson which challenge the students to explain how the structure of the leaf as well as the light-dependent and light-independent reactions are linked to GPP. All of the exam questions have mark schemes that are included in the PowerPoint to allow students to immediately assess their understanding. A number of quick quiz competitions as well as guided discussion points are used to introduce the formulae that calculate NPP and N and to recognise the meaning of the components. Once again, this is immediately followed with an opportunity to apply their understanding to selected questions and the students will have to calculate the efficiency of energy transfer. The remainder of the lesson focuses on the ways that energy is lost at each trophic level and the biology behind the following farming practices are discussed: raising herbivores to reduce the number of trophic levels in a food chain intensely rearing animals to reduce respiratory losses in human food chains the use of fungicides, insecticides and herbicides the addition of artificial fertilisers The ethical issues raised by these practices are also considered and alternative methods discussed such as the addition of natural predators and the use of organic fertilisers like manure
Edexcel GCSE Combined Science Topic B4 REVISION (Natural selection and genetic modification)
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Edexcel GCSE Combined Science Topic B4 REVISION (Natural selection and genetic modification)

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This is a fully-resourced REVISION lesson which challenges the students on their knowledge of the content in TOPIC B4 (Natural selection and genetic modification) of the Edexcel GCSE Combined Science specification. The lesson uses an engaging PowerPoint (65 slides) and accompanying worksheets to motivate students whilst they assess their understanding of this topic. A range of exam questions, differentiated tasks and quiz competitions are used to test the following sub-topics: The discovery of key fossils and their implications for human evolution The dating of stone tools Evolution by natural selection Antibiotic resistance in bacteria as evidence for natural selection The domain and kingdom classification methods Genetic engineering of bacteria to produce human insulin The benefits and risks of genetic engineering and selective breeding The mathematical element of the course is also tested throughout the lesson and students are given helpful hints on exam techniques and how to structure answers. This resource is suitable for use at the end of topic B4 or in the lead up to mocks or the actual GCSE exams.
Gene mutations (WJEC A-level Biology)
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Gene mutations (WJEC A-level Biology)

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This lesson describes the effects of gene mutations can have on amino acid sequences, as illustrated by sickle cell anaemia. The engaging and detailed PowerPoint and accompanying resources are part of the first lesson in a series of 2 lessons which have been designed to cover point (f) in topic 3 of A2 unit 4 of the WJEC A-level Biology specification and includes substitutions, deletions and insertions In order to understand how a change in the base sequence can affect the order of the amino acids, students must be confident in their understanding and application of protein synthesis which was covered earlier in this topic. Therefore, the start of the lesson focuses on transcription and translation and students are guided through the use of the codon table to identify amino acids. Moving forwards, a task called known as THE WALL is used to introduce to the names of three types of gene mutation whilst challenging the students to recognise three terms which are associated with the genetic code. The main focus of the lesson is substitutions and how these mutations may or may not cause a change to the amino acid sequence. The students are challenged to use their knowledge of the degenerate nature of the genetic code to explain how a silent mutation can result. Students will learn that a substitution is responsible for the new allele that causes sickle cell anaemia and they are tested on their understanding through an exam-style question. As with all of the questions, a mark scheme is included in the PowerPoint which can be displayed to allow the students to assess their understanding. The rest of the lesson looks at base deletions and base insertions and students are introduced to the idea of a frameshift mutation. One particular task challenges the students to evaluate the statement that base deletions have a bigger impact on primary structure than base substitutions. This is a differentiated task and they have to compare the fact that the reading frame is shifted by a deletion against the change in a single base by a substitution
Semi-conservative replication of DNA (CIE International A-level Biology)
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Semi-conservative replication of DNA (CIE International A-level Biology)

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This fully-resourced lesson describes how DNA is replicated during interphase and explains why it is semi-conservative replication. Both the detailed PowerPoint and accompanying resources have been designed to cover the details of point 6.1 © of the CIE International A-level Biology specification The main focus of this lesson is the roles of DNA helicase in breaking the hydrogen bonds between nucleotide bases and DNA polymerase incorporating the phosphorylated nucleotides into the sequence. Students are also introduced to DNA ligase to enable them to understand how this enzyme functions to join the nucleic acid fragments. Time is taken to explain key details such as the assembly of strands in the 5’-to-3’ direction so that the continuous manner in which the leading strand is synthesised can be compared against that of the lagging strand. The students are constantly challenged to make links to previous topics such as DNA structure, phosphorylated nucleotides and hydrolysis reactions through a range of exam questions and answers are displayed so any misconceptions are quickly addressed. The main task of the lesson asks the students to use the information provided in the lesson to order the sequence of events in DNA replication before discussing how the presence of a conserved strand and a newly built strand in each new DNA molecule shows that it is semi-conservative.
Spearman's rank correlation (CIE A-level Biology)
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Spearman's rank correlation (CIE A-level Biology)

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This lesson describes how to use the Spearman’s rank correlation to analyse the relationships between the distribution of species and abiotic and biotic factors. The PowerPoint and accompanying exam-style question are the first lesson in a series of 2 which have been designed to cover point 18.1 (e) of the CIE A-level Biology specification and challenges the students on their knowledge of the t-test as covered in topic 17 as well as preparing students for the next lesson on the use of the Pearson’s linear correlation formula. As with the lessons on the t-test and Simpson’s index of diversity, a step by step guide is used to walk the students through the use of the formula to generate the rank coefficient and to determine whether there is a positive correlation, no correlation or a negative correlation. The students are also reminded of the null hypothesis and will be shown how to accept or reject this hypothesis and to determine significance. The students will work through an example with the class and then are given the opportunity to apply their newly-acquired knowledge to an exam-style question which assesses whether there is a relationship between light intensity and % plant cover in a habitat. The mark scheme is displayed on the PowerPoint so the students can assess their understanding and address any misconceptions that may arise
Biuret test & 1.4.1 REVISION (AQA A-level Biology)
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Biuret test & 1.4.1 REVISION (AQA A-level Biology)

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This lesson describes the biuret test for proteins and then uses a range of activities to challenge the students on their knowledge of topic 1.4.1. The engaging PowerPoint and accompanying resources are part of the last lesson in a series of 3 lessons which have been designed to cover the content detailed in topic 1.4.1 (General properties of proteins) of the AQA A-level Biology specification. The first section of the lesson describes the steps in the biuret test and challenges the students on their recall of the reducing sugars and starch tests from topic 1.2 to recognise that this is a qualitative test that begins with the sample being in solution. The students will learn that the addition of sodium hydroxide and then copper sulphate will result in a colour change from light blue to lilac if a protein is present. The remainder of the lesson uses exam-style questions with displayed mark schemes, understanding checks and quick quiz competitions to engage and motivate the students whilst they assess their understanding of this topic. The following concepts are tested during this lesson: The general structure of an amino acid The formation of dipeptides and polypeptides through condensation reactions The primary, secondary, tertiary and quaternary structure of a protein Biological examples of proteins and their specific actions (e.g. antibodies, enzymes, peptide hormones)
Active transport (CIE International A-level Biology)
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Active transport (CIE International A-level Biology)

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This fully-resourced lesson describes the processes of active transport, endocytosis and exocytosis and explains the need for ATP. The PowerPoint and accompanying worksheets have been designed to cover the second part of point 4.2 (a) of the CIE International A-level Biology specification. The first part of 4.2 (a), concerning simple and facilitated diffusion, was covered in the previous lesson. The start of the lesson challenges the students to use their prior knowledge of biological molecules to come up with the abbreviation ATP and they will learn that this is a phosphorylated nucleotide that contains adenine, ribose and three phosphate groups. Students may not have known this as the energy currency from GCSE so time is taken to explain that this molecule must be broken down to release energy and students are challenged to recall which type of reaction will be involved and to predict the products of such a reaction. This hydrolysis of ATP can be coupled to energy-requiring reactions within the cell and the rest of the lesson focuses on the use of this energy for active transport, endocytosis and exocytosis. Students are challenged to answer a series of questions which compare active transport against the forms of passive transport and to use data from a bar chart to support this form of transport. In answering these questions they will discover that carrier proteins are specific to certain molecules and time is taken to look at the exact mechanism of these transmembrane proteins. A quick quiz round introduces endocytosis and the students will see how vesicles are involved along with the energy source of ATP to move large substances in or out of the cell. The lesson concludes with a link to a future topic as the students are shown how exocytosis is involved in a synapse.
Continuous & discontinuous variation (CIE A-level Biology)
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Continuous & discontinuous variation (CIE A-level Biology)

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This fully-resourced lesson describes the differences between continuous and discontinuous variation. The engaging PowerPoint and accompanying resources have been designed to cover point 17.1 (a) of the CIE A-level Biology specification but also acts as a revision of topic 16 as it challenges students on their knowledge of gene mutations and meiosis. The students begin the lesson by having to identify phenotype and species from their respective definitions so that a discussion can be encouraged where they will recognise that phenotypic variation within a species is due to both genetic and environmental factors. The main part of the the lesson focuses on these genetic factors, and describes how mutation and the events of meiosis contribute to this variation. A range of activities, which include exam-style questions and quick quiz rounds, are used to challenge the students on their knowledge and understanding of substitution mutations, deletions, insertions, the genetic code, crossing over and independent assortment. Moving forwards, the concept of multiple alleles is introduced and students will learn how the presence of more than 2 alleles at a locus increases the number of phenotypic variants. Another quick quiz round is used to introduce polygenic inheritance and the link is made between this inheritance of genes at a number of loci as an example of continuous variation. In line with the title of the lesson, the next task challenges them to recognise descriptions and examples which apply to the different types of variations. The final part of the lesson introduces a few examples where environmental factors affect phenotype, such as chlorosis in plants, so that students are prepared for the following lesson.
Properties and roles of water (OCR A-level Biology)
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Properties and roles of water (OCR A-level Biology)

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This detailed lesson describes the relationship between the structure, properties and roles of water for living organisms. The engaging PowerPoint and accompanying resource have been designed to cover the details of specification point 2.1.2 (a) of the OCR A-level Biology A course and has been specifically designed to ensure that each role is illustrated using an example in prokaryotes or eukaryotes. As this is the first lesson in the biological molecules sub-module (2.1.2), which is a topic that students tend to find difficult or potentially less engaging, the planning has centred around the inclusion of a wide variety of tasks to cover the content whilst maintaining motivation and engagement. These tasks include current understanding and prior knowledge checks, discussion points and quick quiz competitions to introduce key terms and values in a memorable way. The start of the lesson considers the structure of water molecules, focusing on the covalent and hydrogen bonds, and the dipole nature of this molecule. Time is taken to emphasise the importance of these bonds and this property for the numerous roles of water and then over the remainder of the lesson, the following properties are described and discussed and linked to real-life examples: As a solvent to act as a transport medium in blood plasma Molecules are attracted by cohesive forces to enable transport in the xylem High latent heat of vaporisation for thermoregulation High specific heat capacity for the maintenance of a stable environment Peak density in the liquid form allowing ice to float The final part of the lesson introduces condensation and hydrolysis reactions and students will learn that a clear understanding of these reactions is fundamental as they will reappear throughout the module in the synthesis and breakdown of biological molecules.
Ventilation and gas exchange in insects (OCR A-level Biology)
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Ventilation and gas exchange in insects (OCR A-level Biology)

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This lesson describes the mechanisms of ventilation and gas exchange in insects. The PowerPoint and accompanying worksheets are the part of the second lesson in a series of 2 lessons which have been designed to cover the details that are set out in point 3.1.1 (f) of the OCR A-level Biology A specification. The first lesson in this series describes ventilation and gas exchange in bony fish In the previous lesson, the students were introduced to the different circulatory systems of mammals and bony fish and this knowledge is checked upon at the start of this lesson. This is relevant because the open circulatory system of an insect explains how oxygen is not transported in the blood but instead is absorbed from the body fluid that bathes the tissues. The next part of the lesson describes the structure of the spiracles, tracheae and tracheoles in the tracheal system and explains how this system is responsible for the delivery of oxygen to the open end of the tracheole for gas exchange with this fluid. As the tracheae are supported by chitin, which is similar in structure and function to cellulose and keratin respectively, a series of exam-style questions are used to challenge the students on their knowledge of those polymers from module 2.1.2 (biological molecules). As always, the mark scheme is embedded in the powerpoint so students can assess their understanding and progress. The final part of the lesson describes how squeezing of the tracheoles by the flight muscles and the changes in the volume of the thorax as a result of the movement of the wings are similar to mechanisms observed in mammals.
Nucleotides (OCR A-level Biology)
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Nucleotides (OCR A-level Biology)

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This detailed lesson describes the structure of a nucleotide and a phosphorylated nucleotide and explains how polynucleotides are synthesised and broken down. The engaging PowerPoint has been designed to cover points [a], [b] and [c] of module 2.1.3 as detailed in the OCR A-level Biology A specification and links are made throughout to earlier topics such as biological molecules. Students were introduced to the term monomer and nucleotide in the previous module, so the start of the lesson challenges them to recognise this latter term when only the letters U, C and T are shown. This has been designed to initiate conversations about why only these letters were used so that the nitrogenous bases can be discussed later in greater detail. Moving forwards, students will learn that a nucleotide is the monomer to a polynucleotide and that deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are two examples of this type of polymer. The main part of the lesson has been filled with various tasks that explore the structural similarities and structural differences between DNA and RNA. This begins by describing the structure of a nucleotide as a phosphate group, a pentose sugar and a nitrogenous base. Time is taken to consider the details of each of these three components which includes the role of the phosphate group in the formation of a phosphodiester bond between adjacent nucleotides on the strand. At this point students are challenged on their understanding of condensation reactions and have to identify how the hydroxyl group associated with carbon 3 is involved along with the hydroxyl group of the phosphoric acid molecule. A number of quiz rounds are used during this lesson, as a way to introduce key terms in a fun and memorable way. One of these rounds introduces adenine and guanine as the purine bases and thymine, cytosine and uracil as the pyrimidine bases and the students are shown that their differing ring structures can be used to distinguish between them. The remainder of the lesson focuses on ADP and ATP as phosphorylated nucleotides and links are made to the hydrolysis of this molecule for energy driven reactions in cells such as active transport
The roles of enzymes & mechanism of action (OCR A-level Biology)
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The roles of enzymes & mechanism of action (OCR A-level Biology)

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This fully-resourced lesson describes the roles of enzymes in catalysing both intracellular and extracellular reactions and the mechanism of enzyme action. The engaging PowerPoint and accompanying resources have been designed to cover points 2.1.4 (a, b & c) of the OCR A-level Biology A specification and includes descriptions of Fischer’s lock and key hypothesis and Koshland’s induced-fit model as well as a focus on catalase and the digestive enzymes as intracellular and extracellular enzymes respectively. The lesson has been specifically planned to tie in with module 2.1.2 where protein structure and globular proteins were covered. This prior knowledge is tested through a series of exam-style questions along with current understanding and mark schemes are included in the PowerPoint so that students can assess their answers. Students will learn that enzymes are large globular proteins which contain an active site that consists of a small number of amino acids. Emil Fischer’s lock and key hypothesis is introduced to enable students to recognise that their specificity is the result of an active site that is complementary in shape to a single type of substrate. Time is taken to discuss key details such as the control of the shape of the active site by the tertiary structure of the protein. The induced-fit model is described so students can understand how the enzyme-susbtrate complex is stabilised and then students are challenged to order the sequence of events in an enzyme-controlled reaction. The final part of the lesson focuses on intracellular and extracellular enzymes. The students are challenged on their recall of the roles of DNA helicase and polymerase in DNA replication before they are challenged on their ability to apply their knowledge and understanding to an unfamiliar situation with questions about catalase and its role in the decomposition of hydrogen peroxide. The lesson concludes with one further set of exam-style questions that challenge their knowledge of carbohydrates, lipids and proteins from module 2.1.3 as they have to recognise some extracellular digestive enzymes from descriptions of their substrates.
The sliding filament model of MUSCULAR CONTRACTION (OCR A-level Biology A)
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The sliding filament model of MUSCULAR CONTRACTION (OCR A-level Biology A)

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This is a fully-resourced lesson that covers the content of specification point 5.1.5 (l) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of the sliding filament model of muscular contraction. The wide range of activities included in the lesson will engage and motivate the students whilst the understanding and previous knowledge checks will not only allow them to assess their progress but also challenge them to make links to other Biology topics. The lesson begins by using an idea from the quiz show POINTLESS to get them to recognise that myology is the study of muscles. This leads nicely into the next task, where they have to identify three further terms (from 12) which will also begin with myo and are the names of structures involved in the arrangement of skeletal muscle. Key terminology is used throughout the lesson so that students feel comfortable when they encounter this in questions. Students are introduced to the sarcomere and the bands and zones that are found within a myofibril so they can discover how most of these structures narrow but the A band, which is the length of the myosin filament, stays the same length between resting and contracted muscle. This has been designed to lead into a discussion point where they are encouraged to consider how the sarcomere can narrow but the lengths of the myofilaments can remain the same. The main task of the lesson involves the formation of a bullet point description of the sliding filament model where one event is the trigger for the next. Time is taken during this section to focus on the involvement of the calcium ions but also ATP and the idea of the sources of this molecule, including creatine phosphate, are discussed in more detail later in the lesson. The final part of the lesson involves students having to apply their knowledge by describing the effect on muscle contraction when a part of a structure is unable to function correctly. This lesson has been designed for students studying the OCR A-level Biology course and ties in nicely with the other lessons on this particular topic such as neuromuscular junctions as well as the other uploaded lessons from module 5