NB-This resource has been edited since the last review* [30/9/17] Screening for genetic disorders lesson created in accordance to the NEW AQA Specification (9-1). Designed for a higher ability TRILOGY(combined science) class, although content can be adjusted to suit any ability. Includes: slide animations, embedded videos and practice questions with answers on slides as well as a quiz. This video contains many videos and is a great lesson to spark a debate. I'd appreciate a review after your lesson :) AQA spec link: 6.1.7 Relevant chapter: B13 Genetics and reproduction. AQA Biology third edition textbook-Page 214-215. Some disorders are inherited. These disorders are caused by the inheritance of certain alleles. • Polydactyly (having extra fingers or toes) is caused by a dominant allele. • Cystic fibrosis (a disorder of cell membranes) is caused by a recessive allele. Students should make informed judgements about the economic, social and ethical issues concerning embryo screening, given appropriate information. WS 1.3 Appreciate that embryo screening and gene therapy may alleviate suffering but consider the ethical issues which arise.

This lesson has been created in accordance to the NEW AQA Specification (9-1) for my combined/additional science class (Year 9-KS4). Includes: slide animations, embedded video, worksheet, quiz, practice exam questions and answers have also been included within the slides. This resource is suitable for separate science students. AQA spec link: Relevant chapter: B5-Communicable diseases . AQA Biology third edition textbook-Page 90-91. *The new specification requires students to know the following; Students should be able to describe the non-specific defence systems of the human body against pathogens, including the: • skin • nose • trachea and bronchi • stomach. Students should be able to explain the role of the immune system in the defence against disease. If a pathogen enters the body the immune system tries to destroy the pathogen. White blood cells help to defend against pathogens by: • phagocytosis • antibody production • antitoxin production.

The history of genetics lesson created in accordance to the NEW AQA Specification (9-1). Designed for a separates class. Includes: embedded videos and timers, slide animations, practice questions with answers on slides, worksheet and an interactive quiz. NB: If you are unable to play videos a URL link can be found in the slide notes. AQA spec link: 4.6.3.3 Relevant chapter: B15 Genetics and evolution. AQA Biology trilogy edition textbook-Page 234-235 Students are required to know the following; Students should be able to: • describe the development of our understanding of genetics including the work of Mendel • understand why the importance of Mendel’s discovery was not recognised until after his death. In the mid-19th century Gregor Mendel carried out breeding experiments on plants. One of his observations was that the inheritance of each characteristic is determined by ‘units’ that are passed on to descendants unchanged. In the late 19th century behaviour of chromosomes during cell division was observed. WS 1.1 Our current understanding of genetics has developed over time. In the early 20th century it was observed that chromosomes and Mendel’s ‘units’ behaved in similar ways. This led to the idea that the ‘units’, now called genes, were located on chromosomes. In the mid-20th century the structure of DNA was determined and the mechanism of gene function worked out. This scientific work by many scientists led to the gene theory being developed.

Inheritance in action lesson created in accordance to the NEW AQA Specification (9-1). Designed for higher ability class, although content can be adjusted to suit any ability. Includes: embedded videos and timers, slide animations, practice questions with answers on slides and an interactive quiz. AQA spec link: 6.1.6 Relevant chapter: B13 Genetics and reproduction. AQA Biology third edition textbook-Page 208-209. Students should be able to explain the terms: • gamete • chromosome • gene • allele • dominant • recessive • homozygous • heterozygous • genotype • phenotype. Some characteristics are controlled by a single gene, such as: fur colour in mice; and red-green colour blindness in humans. Each gene may have different forms called alleles. The alleles present, or genotype, operate at a molecular level to develop characteristics that can be expressed as a phenotype. A dominant allele is always expressed, even if only one copy is present. A recessive allele is only expressed if two copies are present (therefore no dominant allele present). If the two alleles present are the same the organism is homozygous for that trait, but if the alleles are different they are heterozygous. Most characteristics are a result of multiple genes interacting, rather than a single gene. Students should be able to understand the concept of probability in predicting the results of a single gene cross, but recall that most phenotype features are the result of multiple genes rather than single gene inheritance. MS 2e Students should be able to use direct proportion and simple ratios to express the outcome of a genetic cross. MS 1c, 3a Students should be able to complete a Punnett square diagram and extract and interpret information from genetic crosses and family trees. MS 2c, 4a (HT only) Students should be able to construct a genetic cross by Punnett square diagram and use it to make predictions using the theory of probability.

C10-Chemical analysis-Pure substances and mixtures lesson created in accordance to the NEW AQA Specification (9-1). Designed for a low ability year 11 class, although content can be adjusted to suit any ability. Includes: slide animations, embedded videos and practice questions with answers on slides as well as a interactive review task. If for any reason the video link does not work, a URL has also been included in the notes. AQA spec link: 5.8.1.1 and 5.8.1.2 In chemistry, a pure substance is a single element or compound, not mixed with any other substance. Pure elements and compounds melt and boil at specific temperatures. Melting point and boiling point data can be used to distinguish pure substances from mixtures. In everyday language, a pure substance can mean a substance that has had nothing added to it, so it is unadulterated and in its natural state, eg pure milk. Students should be able to use melting point and boiling point data to distinguish pure from impure substances. Many products are complex mixtures in which each chemical has a particular purpose. Formulations are made by mixing the components in carefully measured quantities to ensure that the product has the required properties. Formulations include fuels, cleaning agents, paints, medicines, alloys, fertilisers and foods. Students should be able to identify formulations given appropriate information. Students do not need to know the names of components in proprietary products.

How plants use glucose lesson created in accordance to the NEW AQA Specification (9-1). Designed for a higher ability class, although content can be adjusted to suit any ability. Includes powerpoint timers, slide animations, embedded video’s, practice questions, peer assessment worksheet and mini review. *Top paper friendly tip: the information in the ‘How to use glucose’ worksheet can also be found in the textbook therefore isn’t required to be printed.* NB: If you are unable to play embedded videos please view slide notes for link. AQA spec link: 4.4.1.3 Relevant chapter: B8 Photosynthesis. AQA Biology third edition textbook-Page 128-129 Students are required to know the following; The glucose produced in photosynthesis may be: •• used for respiration •• converted into insoluble starch for storage •• used to produce fat or oil for storage •• used to produce cellulose, which strengthens the cell wall •• used to produce amino acids for protein synthesis. To produce proteins, plants also use nitrate ions that are absorbed from the soil. AT 8-Tests to identify starch, glucose and proteins using simple qualitative reagents

Genetic engineering lesson created in accordance to the NEW AQA Specification (9-1). Designed for higher ability (trilogy/combined) class, although content can be adjusted to suit any ability. Includes: embedded videos and timers, slide animations, practice questions with answers on slides. NB: If you are unable to play videos a URL link can be found in the slide notes. AQA spec link: 4.6.2.4 Relevant chapter: B13 Variation and evolution. AQA Biology trilogy edition textbook-Page 186-187. Students are required to know the following; Students should be able to explain the potential benefits and risks of genetic engineering in agriculture and in medicine and that some people have objections. Concerns about GM crops include the effect on populations of wild flowers and insects. Some people feel the effects of eating GM crops on human health have not been fully explored.

Classification lesson created in accordance to the NEW AQA Specification (9-1). Designed for higher ability class, although content can be adjusted to suit any ability. Includes: embedded videos and timers, slide animations, practice questions with answers on slides, worksheet and an interactive quiz. NB: If you are unable to play videos a URL link can be found in the slide notes. AQA spec link: 4.6.4 Relevant chapter: B14 Genetics and evolution. AQA combined trilogy edition textbook-Page 198-199 Students are required to know the following; Traditionally living things have been classified into groups depending on their structure and characteristics in a system developed by Carl Linnaeus. Linnaeus classified living things into kingdom, phylum, class, order, family, genus and species. Organisms are named by the binomial system of genus and species. Students should be able to use information given to show understanding of the Linnaean system. Students should be able to describe the impact of developments in biology on classification systems.

C13-The Earth’s atmosphere-Our evolving atmosphere lesson created in accordance to the NEW AQA Specification (9-1). Designed for a mixed ability year 11 separates class, although content can be adjusted to suit any ability. Includes: slide animations, embedded videos, and homework with answers as well as a interactive review task. If for any reason the video link does not work, a URL has also been included in the notes. For further enquiries please email paperfriendlyresources@gmail.com AQA spec link: 4.9.1.1, 2, 4 AQA spec link: For 200 million years, the proportions of different gases in the atmosphere have been much the same as they are today: • about four-fifths (approximately 80%) nitrogen • about one-fifth (approximately 20%) oxygen • small proportions of various other gases, including carbon dioxide, water vapour, and noble gases. Volcanoes also produced nitrogen which gradually built up in the atmosphere and there may have been small proportions of methane and ammonia. Algae and plants decreased the percentage of carbon dioxide in the atmosphere by photosynthesis. Carbon dioxide was also decreased by the formation of sedimentary rocks and fossil fuels that contain carbon. Students should be able to: • describe the main changes in the atmosphere over time and some of the likely causes of these changes • describe and explain the formation of deposits of limestone, coal, crude oil, and natural gas.

Diet, exercise and disease lesson created in accordance to the NEW AQA Specification (9-1). Designed for a higher ability class, although content can be adjusted to suit any ability. Includes powerpoint timers, slide animations, embedded video's, worksheet and mini review. NB: If you are unable to play embedded videos please view slide notes for link. AQA spec link: 4.2.2.6 Relevant chapter: B7 Non-communicable diseases. AQA Biology combined textbook-Page 104-105 Students are required to know the following; • discuss the human and financial cost of these non-communicable diseases to an individual, a local community, a nation, or globally • explain the effect of lifestyle factors including diet, alcohol, and smoking on the incidence of non-communicable diseases at local, national, and global levels. Risk factors are linked to an increased rate of a disease. They can be: • aspects of a person’s lifestyle • substances in the person’s body or environment. A causal mechanism has been proven for some risk factors, but not in others. • The effects of diet and exercise on cardiovascular disease. • Obesity as a risk factor for Type 2 diabetes. Many diseases are caused by the interaction of a number of factors. Students should be able to understand the principles of sampling as applied to scientific data in terms of risk factors. Students should be able to translate information between graphical and numerical forms; and extract and interpret information from charts, graphs and tables in terms of risk factors. Students should be able to use a scatter diagram to identify a correlation between two variables in terms of risk factors.

The human Kidney lesson created in accordance to the NEW AQA Specification (9-1) for my separates class (Year 10-KS4). This is a printer friendly resource it includes an: embedded video, slide animations and a mini exam question. As i taught this lesson in two parts it's only fair i upload the other presentation also (2 for the price of 1). **Knowledge of other parts of the urinary system, the structure of the kidney, and the structure of a nephron is not required.** AQA spec link: 5.3.3 Relevant chapter: B12-Homeostasis in action. ( Note: This topic is for BIOLOGY only not for combined science students). AQA Biology third edition textbook-Page 185-186 *The new specification requires students to know the following; Students should be able to describe the function of kidneys in maintaining the water balance of the body. The kidneys produce urine by filtration of the blood and selective reabsorption of useful substances such as glucose, some ions, And water. Knowledge of other parts of the urinary system, the structure of the kidney, and the structure of a nephron is not required. Students should be able to translate tables and bar charts of glucose, ions, and urea before and after filtration. Students should be able to describe the effect of ADH on the permeability of the kidney tubules. The water level in the body is controlled by the hormone ADH which acts on the kidney tubules. ADH is released by the pituitary gland when the blood is too concentrated and it causes more water to be reabsorbed back into the blood from the kidney tubules. This is controlled by negative feedback.

Theories of evolution lesson created in accordance to the NEW AQA Specification (9-1). Designed for a separates class. Includes: embedded videos and timers, slide animations, practice questions with answers on slides, worksheet and an interactive quiz. NB: If you are unable to play videos a URL link can be found in the slide notes. AQA spec link: 4.6.3.1 Relevant chapter: B15 Genetics and evolution. AQA Biology trilogy edition textbook-Page 236-237 Students are required to know the following; Charles Darwin, largely as a result of observations on a round the world expedition, linked to developing knowledge of geology and fossils, proposed the theory of natural selection: • Individual organisms within a particular species show a wide range of variation for a characteristic. • Individuals with characteristics most suited to the environment are more likely to survive to breed successfully. • The characteristics that have enabled these individuals to survive are then passed on to the next generation. Other theories, including that of Jean-Baptiste Lamarck, are based mainly on the idea that changes that occur in an organism during its lifetime can be inherited. We now know that in the vast majority of cases this type of inheritance cannot occur. A study of creationism is not required.

Types of reproduction lesson created in accordance to the NEW AQA Specification (9-1). Designed for a separates class, although content can be adjusted to suit any ability. Includes: slide animations, embedded videos and practice questions with answers on slides as well as a quiz. AQA spec link: 6.1.1 Relevant chapter: B13 Genetics and reproduction. AQA Biology third edition textbook-Page 196-197. Specification requires students to know the following; Students should understand that meiosis leads to non-identical cells being formed while mitosis leads to identical cells being formed. Sexual reproduction involves the joining (fusion) of male and female gametes: • sperm and egg cells in animals • pollen and egg cells in flowering plants. In sexual reproduction there is mixing of genetic information which leads to variety in the offspring. The formation of gametes involves meiosis. Asexual reproduction involves only one parent and no fusion of gametes. There is no mixing of genetic information. This leads to genetically identical offspring (clones). Only mitosis is involved. Biology only-6.1.3 Advantages of sexual reproduction: • produces variation in the offspring • if the environment changes variation gives a survival advantage by natural selection • natural selection can be speeded up by humans in selective breeding to increase food production. Advantages of asexual reproduction: • only one parent needed • more time and energy efficient as do not need to find a mate • faster than sexual reproduction • many identical offspring can be produced when conditions are favourable Good luck with your lesson!

Genetic engineering lesson created in accordance to the NEW AQA Specification (9-1). Designed for higher ability (trilogy/combined) class, although content can be adjusted to suit any ability. Includes: embedded videos and timers, slide animations, practice questions with answers on slides, worksheet and an interactive quiz. NB: If you are unable to play videos a URL link can be found in the slide notes. AQA spec link: 4.6.2.4 Relevant chapter: B13 Variation and evolution. AQA Biology trilogy edition textbook-Page 184-185. Students are required to know the following; Students should be able to describe genetic engineering as a process which involves modifying the genome of an organism by introducing a gene from another organism to give a desired characteristic. Plant crops have been genetically engineered to be resistant to diseases or to produce bigger better fruits. Bacterial cells have been genetically engineered to produce useful substances such as human insulin to treat diabetes. Students should be able to explain the potential benefits and risks of genetic engineering in agriculture and in medicine and that some people have objections. In genetic engineering, genes from the chromosomes of humans and other organisms can be ‘cut out’ and transferred to cells of other organisms. Crops that have had their genes modified in this way are called genetically modified (GM) crops. GM crops include ones that are resistant to insect attack or to herbicides. GM crops generally show increased yields. Concerns about GM crops include the effect on populations of wild flowers and insects. Some people feel the effects of eating GM crops on human health have not been fully explored. Modern medical research is exploring the possibility of genetic modification to overcome some inherited disorders. (HT) Students should be able to describe the main steps in the process of genetic engineering. In genetic engineering: • enzymes are used to isolate the required gene; this gene is inserted into a vector, usually a bacterial plasmid or a virus • the vector is used to insert the gene into the required cells • genes are transferred to the cells of animals, plants, or microorganisms at an early stage (egg or embryo) in their development so that they develop with desired characteristics.

Hormones and menstrual cycle lesson created in accordance to the NEW AQA Specification (9-1) for my separates class (Year 10-KS4). Includes: slide animations, embedded video, worksheet and practice questions with mark scheme. This resource is suitable for combined science students. *Note-For higher tier only* AQA spec link:5.3.4 Relevant chapter: B11 -Hormonal coordination . AQA Biology third edition textbook-Page 170-171. *The new specification requires students to know the following; Students should be able to explain the interactions of FSH, oestrogen, LH and progesterone, in the control of the menstrual cycle. Students should be able to extract and interpret data from graphs showing hormone levels during the menstrual cycle.

C2-Development of the periodic table homework created in accordance to the NEW AQA Specification (9-1). This is a great flip learning activity, give yourself a little break and allow your students to present their timelines/fact sheets :) For further enquiries please email paperfriendlyresources@gmail.com Also available via instagram: Paperfriendlyresourcesuk AQA spec link: 4.1.2.2