This fully-resourced lesson explores the inheritance of sex-linked diseases in humans and then challenges the students to apply their knowledge to examples in other animals. The detailed PowerPoint and associated differentiated resources have been designed to cover the part of point 6.1.2 (b[i]) of the OCR A-level Biology A specification which states that students should be able to demonstrate and apply their knowledge and understanding of genetic diagrams which include sex-linkage. Key genetic terminology is used throughout and the lesson begins with a check on their ability to identify the definition of homologous chromosomes. Students will recall that the sex chromosomes are not fully homologous and that the smaller Y chromosome lacks some of the genes that are found on the X. This leads into one of the numerous discussion points, where students are encouraged to consider whether females or males are more likely to suffer from sex-linked diseases. In terms of humans, the lesson focuses on haemophilia and red-green colour blindness and a step-by-step guide is used to demonstrate how these specific genetic diagrams should be constructed and how the phenotypes should then be interpreted. The final tasks of the lesson challenge the students to carry out a dihybrid cross that involves a sex-linked disease and an autosomal disease before applying their knowledge to a question about chickens and how the rate of feather production in chicks can be used to determine gender. All of the tasks are differentiated so that students of differing abilities can access the work and all exam questions have fully-explained, visual markschemes to allow them to assess their progress and address any misconceptions.

An engaging lesson presentation which looks at the two types of animal stem cells, exploring their important differences and briefly looking at their potential uses in medicine. The lesson begins by looking at the meaning of the term differentiation and then challenging students to draw a simple conclusion once they know that stems cells are undifferentiated cells. Time is taken to look into this part of the knowledge in depth but then students are given the key points which must be understood for them to move forwards. Students are told that there are two types of animal stem cells before a quiz competition is used to get them to predict which one of the two is being described by the clues. The answers to the competition then have to be used to write a summary passage about the two types. Students are also told that stem cells exist in plants in the form of meristem cells. Finally, Parkinson’s disease and Diabetes mellitus Type I are used as examples of conditions that could be potentially treated with stem cells.

A thought-provoking lesson presentation (34 slides) that looks at each of the stages in the development of drugs and considers the potential issues that arise at each of the stages. The lesson begins by ensuring that the students know the scientific definition of a drug and then they will be told how much is spent by the NHS alone each year on medicinal drugs so they can recognise the importance of this topic. Moving forwards, each stage in the development is considered in the appropriate detail. Students are challenged to consider some stages from both a scientific angle and a business angle so they can understand why certain animals are chosen for the testing. Key terms such as placebo and double blind trial are introduced and discussion time is written into the lesson so that insightful questions can be posed by all. There are regular progress checks throughout the lesson to allow the students to check on their understanding. This lesson has been written for GCSE students but could be used with KS3 students who might be carrying out research or a project on the topic of drugs.

A detailed lesson presentation and associated question worksheet which uses a step by step guide and numerous worked examples to show students how to draw genetic crosses to calculate offspring percentages. Before students are able to draw genetic diagrams, they need to understand and be able to use genetic terminology so this is the focus for the start of the lesson. Time is taken to go over the meaning of dominant and recessive alleles, genotypes and phenotypes. Moving forwards, students will be challenged to link genotypes to phenotypes for both dominant and recessive disorders and common misconceptions such as carriers in recessive disorders are explained. Finally, a 5 step guide is used to walk students through drawing genetic diagrams. Students are then given a chance to apply their new-found knowledge to questions about the inheritance of cystic fibrosis and polydactyly. Progress checks have been written into the lesson at regular intervals so that students can assess their understanding. This lesson has been designed for GCSE students but is perfectly suitable for A-level students who are studying the topic of monogenic inheritance

An engaging and informative lesson presentation (40 slides) that looks at the different steps that have to be taken when trying to identify potential donors for organ transplants. Links are made throughout the lesson to related topics such as the human defence systems and blood groups. The lesson begins by challenging the students to use their knowledge of the body’s defences to explain why closely matching tissues is critical when choosing a donor. Moving forwards, students will see how the four blood groups in the ABO system need to receive certain bloods and can only be given to certain others. There is a brief discussion of the HLA antigens and why this needs to be matched. The remainder of the lesson focuses on immuno-suppressant drugs and the advantages and disadvantages to individuals of taking these drugs. Progress checks have been written into the lesson at regular intervals to allow the students to constantly assess their understanding and any misconceptions to be addressed. This lesson has been written for GCSE students

A fully-resourced lesson which looks at how auxins are involved in the response to the stimuli and gravity. The lesson includes an engaging lesson presentation (29 slides) and associated worksheets which have been differentiated. The lesson begins by challenging students to consider the different stimuli that a plant will respond to. There is focus throughout the lesson on the use of key terminology and students will start immediately by meeting the different types of tropisms. A quick competition is used to introduce the students to auxins and the key details of these chemicals are discussed. They will see how they are produced in the tips of shoots and roots and cause cell elongation in the shoots. A summary task is used to get the students to explain how a plant grow towards a light source. The next task challenges the students to apply their knowledge as a range of experimental data is shown to them and they have to predict how the plant would respond and explain - this task has been differentiated two ways so those students who need extra assistance can access the learning. The final part of the lesson looks at gravitropism and all of the learning is brought together to explain how the shoots grow away and the roots towards. This lesson has been written for GCSE students.

An engaging lesson presentation (34), accompanied by a summary worksheet, which together explore the factors which change the rate of transpiration and focuses on the explanation behind each factor. The lesson begins by introducing the term, transpiration, and linking this to the structure of a leaf to ensure that students know that water is lost as water vapour out of the stomata. Students are provided with an analogy of plants being like clothes on a washing line to challenge them to come up with some of the factors involved. Time is taken to look specifically at humidity as this is a factor which is commonly misunderstood. Moving forwards, students are challenged to draw sketch graphs to predict whether increasing each of these factors will increase the rate of transpiration or decrease it. A series of questions to lead to answers is used to show the students how to explain the effect of increasing the light intensity. The remainder of the lesson looks at a potometer and how it can be used to calculate the rate. The mathematical skills of the students are challenged during a range of tasks and then linked back to the Science so they can recognise which features of plants will help to reduce water loss. Progress checks are written into this lesson at regular intervals to allow students to assess their understanding and a number of quick competitions act to maintain engagement. This lesson has been written for GCSE students but is suitable for A-level students who are studying the plants topic

A fast-paced lesson that explores the meaning of “health” and introduces the idea of communicable and non-communicable diseases. The lesson begins by showing the students an example of a health survey so they can complete a definition of the meaning of this term. Despite being widely used in the English language, the actual Scientific definition is not always well known by students so this 1st task is an important one. Moving forwards, students are given 5 minutes to see if they can fill an A-Z with the names of different diseases. Students will learn that diseases can be grouped as communicable or non-communicable and will be encouraged to discuss what the determining factor is on this classification. A quiz competition called “TO COM or NOT TO COM” is a play on words of Shakespeare’s famous saying but acts to test whether the students can distinguish a number of diseases as being spread by pathogens or not. After each disease is revealed, time is taken to look at the details of some of them like cystic fibrosis and the zika virus. The lesson concludes with the example of the human-papilloma virus and the connection between this and cervical cancer so that students can recognise that sometimes both types of disease are involved. This lesson has been written for GCSE students (14 - 16 year olds in the UK) but could be used with younger students who are looking at the healthy living topic.

This lesson describes and explains how increasing the concentration of inhibitors affects the rate of an enzyme-catalysed reaction. The PowerPoint and accompanying resource are the last in a series of 4 lessons which cover the content detailed in point 3.2 (a) of the CIE A-level Biology specification but this lesson also covers point 3.2 [c] as competitive and non-competitive inhibitors are introduced and their differing effects on enzyme activity described and explained. The lesson begins with a made up round of the quiz show POINTLESS called “Biology opposites” and this allows students to recognise that inhibition is the opposite of stimulation. This introduces inhibitors as substances that reduce the rate of a reaction and students are challenged to use their general knowledge of enzymes to identify that inhibitors prevent the formation of the enzyme-substrate complex. Moving forwards, a quick quiz competition generates the abbreviation EIC (representing enzyme-inhibitor complex) and this introduces competitive inhibitors as substances that occupy the active site. The students are asked to apply their knowledge to a new situation to work out that these inhibitors must have a similar shape to the enzyme’s substrate molecule. A series of exam-style questions are used throughout the lesson and at this point, the students are challenged to work out that an increase in the substrate concentration would reduce the effect of a fixed concentration of a reversible competitive inhibitor. The rest of the lesson focuses on non-competitive inhibitors and time is taken to ensure that key details such as the disruption of the tertiary structure is understood and biological examples are used to increase the relevance. Again, students will learn that increasing the concentration of the inhibitor results in a greater inhibition and a reduced rate of reaction but that increasing the substrate concentration cannot reduce the effect as was observed with competitive inhibitors.

This detailed lesson describes how an endotherm regulates its temperature through behaviour and also physiologically. The engaging PowerPoint and accompanying resources have been designed to cover specification point 9.9 (vii) of the Edexcel A-level Biology B specification and includes descriptions of the roles of the autonomic nervous system, thermoreceptors, hypothalamus and skin. A wide range of activities have been written into this lesson so that students remain motivated throughout and take a genuine interest in the content. Understanding checks allow the students to assess their progress whilst the prior knowledge checks on topics such as enzymes and denaturation demonstrate the importance of being able to make connections and links between topics from across the specification. In addition to these checks, quiz competitions like HAVE an EFFECT which is shown in the cover image are used to introduce key terms and values in a fun and memorable way. The lesson begins by introducing the key term, endotherm, and challenging students to use their prior knowledge and understanding of terminology to suggest what this reveals about an organism. Moving forwards, students will learn how the heat generated by metabolic reactions is used as a source of internal heat. The main part of the lesson focuses on thermoregulation in humans (mammals) and time is taken to focus on the key components, namely the sensory receptors, the thermoregulatory centre in the hypothalamus and the responses brought about by the skin. The important details of why the transfer of heat energy between the body and the environment actually leads to a decrease in temperature are explored and discussed at length to ensure understanding is complete. Students are challenged to write a detailed description of how the body detects and responds to a fall in body temperature and this task is differentiated for those students who need some extra assistance. The peripheral thermoreceptors are introduced and this leads into the final section of the lesson that considers behavioural responses in humans and other animals.

This fully-resourced lesson looks at the use of electrocardiograms to aid the diagnosis of abnormal heart rhythms. The engaging PowerPoint and accompanying resources have been designed to cover point 7.12 (iii) of the Edexcel International A-level Biology specification but also can be used as a revision lesson as the students are challenged on their prior knowledge of the cardiac cycle and heart structure as covered in topic 1. The lesson has been written to take place in an imaginary cardiology ward where the students are initially challenged on their knowledge of the symptoms and risk factors of CVD before looking at testing through the use of ECGs and diagnosis. The main focus of the lesson is the ECG and a quiz competition is used to introduce the reference points of P, QRS and T before time is taken to explain their representation with reference to the cardiac cycle. Moving forwards, a SPOT the DIFFERENCE task is used to challenge the students to recognise differences between sinus rhythm and some abnormal rhythms including tachycardia and atrial fibrillation. Bradycardia is used as a symptom of sinus node disfunction and the students are encouraged to discuss this symptom along with some others to try to diagnose this health problem. This lesson has been designed to tie in with the lesson that covers the previous specification point on the normal electrical activity of the heart and the myogenic nature of cardiac muscle

This lesson describes how to prepare and examine microscope slides and the use of staining in light microscopy. The PowerPoint and accompanying resources have been designed to cover points 2.1.1 (b & c) of the OCR A-level Biology A specification and describe how the eyepiece graticule and stage micrometer are used to measure the size of an object with a light microscope and the use of eosin and methylene blue. The main task of this lesson involves a step by step guide which walks students through the methodology and the use of the scale on the stage micrometer to identify the size of the divisions of the eyepiece graticule and this will need them to convert between units. Moving forwards, the students are challenged to apply this method to a series of exam-style questions and the mark scheme is displayed on the PowerPoint so that they can assess their understanding. In the last lesson, they were briefly introduced to the idea that some specimens need to be stained as light passes completely through transparent samples and the remainder of the lesson builds on this knowledge. Students will learn that cell populations, structures within cells and biological tissues can be distinguished using stains and a series of questions will challenge them to make links to biological molecules, organelles and infections. Links are also made to the upcoming topic of epithelial tissue in the respiratory system. This lesson has been specifically written to tie in with the previous lesson on light and electron microscopes and 2 rounds of the sub-module quiz competition are found in this lesson.

This fully-resourced revision lesson uses a range of activities to challenge the students on their knowledge of proteins from module 2.1.2. The engaging PowerPoint and accompanying resources have been designed to test the intricate details of specification points 2.1.2 (k), (l), (m), (n), (o) & (q) The range of activities include exam-style questions with displayed mark schemes, understanding checks and quick quiz competitions that will engage and motivate the students whilst they assess their understanding of this topic. The following concepts are tested during this lesson: The general structure of an amino acid The formation of dipeptides and polypeptides through condensation reactions The primary, secondary, tertiary and quaternary structure of a protein Biological examples of proteins and their specific actions (e.g. antibodies, enzymes, peptide hormones) The biuret test for proteins Time has been taken in the planning to make links to topics in upcoming modules such as the genetic code (2.1.3) and intracellular enzymes (2.1.4)

This lesson describes how an interaction of muscles, tendons, the skeleton and ligaments is needed for movement of the human body. The PowerPoint and accompanying resources have been designed to cover point 7.9 of the Edexcel International A-level Biology specification and also includes descriptions of antagonistic muscle pairs, extensors and flexors. At the start of the lesson, the prep room skeleton is used as the example to show that bones without muscles are bones that are unable to move (unaided). Moving forwards, the students will learn that skeletal muscles are attached to bones by bundles of collagen fibres known as tendons and as they covered the relationship between the structure and function of collagen in topic 2, a task is used that challenges their recall of these details. This will allow them to recognise that the ability of this fibrous protein to withstand tension is important for the transmission of the force from the muscle to pull on the moveable bone. A series of quick quiz competitions introduce the key terms of flexion and antagonistic and then an exam-style question challenges them to recognise the structures involved in extension at the elbow. The remainder of the lesson focuses on the role of ligaments and one final example of extension at the knee joint will demonstrate how the interaction of all of the structures met over the course of the lesson is needed for movement

This is a highly engaging and detailed lesson which looks at the physiological and behavioural responses involved in temperature control in endotherms and therefore covers specification point 5.1.1 (d) of the OCR A-level Biology A specification. A wide range of activities have been written into the PowerPoint and accompanying worksheets so that students remain motivated throughout and take a genuine interest in the content. Understanding checks allow the students to assess their progress whilst the prior knowledge checks on topics such as enzymes and denaturation demonstrate the importance of being able to make connections and links between topics from across the specification. In addition to these checks, quiz competitions like HAVE an EFFECT which is shown in the cover image are used to introduce key terms and values in a fun and memorable way. The lesson begins by introducing the key term, endotherm, and challenging students to use their prior knowledge and understanding of terminology to suggest what this reveals about an organism. Moving forwards, students will learn how the heat generated by metabolic reactions is used as a source of internal heat. The main part of the lesson focuses on thermoregulation in humans (mammals) and time is taken to focus on the key components, namely the sensory receptors, the thermoregulatory centre in the hypothalamus and the responses brought about by the skin. The important details of why the transfer of heat energy between the body and the environment actually leads to a decrease in temperature are explored and discussed at length to ensure understanding is complete. Students are challenged to write a detailed description of how the body detects and responds to a fall in body temperature and this task is differentiated for those students who need some extra assistance. The peripheral thermoreceptors are introduced and this leads into the final section of the lesson that considers behavioural responses in humans and other animals. This lesson has been designed for A-level students studying the OCR A-level Biology A course

This lesson describes how muscles, tendons, the skeleton and ligaments interact to enable movement. The PowerPoint and accompanying resources have been designed to cover point 7.1 of the Pearson Edexcel A-level Biology A (Salters Nuffield) specification and also includes descriptions of antagonistic muscle pairs, extensors and flexors. At the start of the lesson, the prep room skeleton is used as the example to show that bones without muscles are bones that are unable to move (unaided). Moving forwards, the students will learn that skeletal muscles are attached to bones by bundles of collagen fibres known as tendons and as they covered the relationship between the structure and function of collagen in topic 2, a task is used that challenges their recall of these details. This will allow them to recognise that the ability of this fibrous protein to withstand tension is important for the transmission of the force from the muscle to pull on the moveable bone. A series of quick quiz competitions introduce the key terms of flexion and antagonistic and then an exam-style question challenges them to recognise the structures involved in extension at the elbow. The remainder of the lesson focuses on the role of ligaments and one final example of extension at the knee joint will demonstrate how the interaction of all of the structures met over the course of the lesson is needed for movement

This lesson describes the structure and functions of the adrenal glands, and includes the hormones secreted by the cortex and the medulla. The detailed PowerPoint and accompanying resources have been designed to cover point 5.1.4 (b) of the OCR A-level Biology A specification This lesson has been planned to closely tie in with the previous lesson on endocrine communication, and specifically the modes of action of peptide and steroid hormones. At the start of the lesson, the students have to use the knowledge acquired in this last lesson to reveal the key term cortex and this leads into the description of the structure of the adrenal glands in terms of the outer region and the inner region known as the medulla. The main part of the lesson focuses on the range of physiological responses of the organs to the release of adrenaline. Beginning with glycogenolysis, the need for adrenaline to bind to adrenergic receptors is described including the activation of cyclic AMP. A quiz competition is used to introduce other responses including lipolysis, vasodilation, bronchodilation and an increase in stroke volume. Links to previous topics are made throughout the lesson and students are challenged on their knowledge of heart structure and polysaccharides. The final part of the lesson introduces the three zones of the adrenal cortex and the steroid hormones that they produce along with their functions. Once again, a series of exam-style questions are used to challenge their ability to apply their understanding to an unfamiliar situation and to make biological links and the mark schemes are embedded in the PowerPoint.