This revision resource includes exam questions, understanding checks and quiz competitions, all of which have been designed with the aim of motivating and engaging the students whilst they assess their understanding of the content found in topic 5 (Enzymes) of the CIE IGCSE Biology specification for examination in June and November 2020 and 2021. This revision resource contains an engaging PowerPoint (25 slides) and associated worksheet. The range of activities have been designed to cover as much of the Core and supplement content as possible but the following sub-topics have been given particular attention: Define enzymes as proteins that function as biological catalysts Explain enzyme action with reference to active site, substrate and enzyme-substrate complex Explain the specificity of enzymes Explain the effect of changes of temperature on enzyme activity Explain the effect of changes of pH on enzyme activity Describe what happens to an enzyme when it is denatured

This lesson has been designed to cover the content as detailed in points 2.15, 2.16 and 2.17 (The eye as a sensory receptor and the correction of eye defects) of the Edexcel GCSE Biology specification. Consisting of a detailed and engaging PowerPoint (54 slides) and accompanying worksheets, the range of activities will motivate the students whilst ensuring that the content is covered in detail. Students will learn how the structures of the eye enable it to function as a sensory receptor, with a particular focus on the role of the cornea, lens, iris and the rod and cone cells in the retina. In addition, students will understand how eye defects such as short-sightedness and cataracts can cause problems for vision and can be corrected. Progress checks are included throughout the lesson so that students can assess their understanding of the content and any misconceptions can be addressed whilst quiz competitions are used to introduce new terms in a fun and memorable way. This lesson has been written for GCSE-aged students who are studying the Edexcel GCSE Biology specification but can be used with younger students who have a real interest in this sensory receptor as well as older students who need to know the key details for their A level course.

This fully-resourced lesson is clear and concise and has been written to explain how the inheritance of two or more genes that have loci on the same chromosome demonstrates linkage. The engaging PowerPoint and associated resource have been designed to cover point 3.8 (i and ii) of the Pearson Edexcel A-level Biology (Salters Nuffield) specification which states that students should know the meaning of a gene locus and understand the linkage of genes on a chromosome. This is a topic which can cause confusion for students so time was taken in the design to split the concept into small chunks. There is a clear focus on how the number of original phenotypes and recombinants can be used to determine linkage and suggest how the loci of the two genes compare. Important links to other topics such as crossing over in meiosis are made to enable students to understand how the random formation of the chiasma determines whether new phenotypes will be seen in the offspring or not. Linkage is an important cause of variation and the difference between observed and expected results and this is emphasised on a number of occasions. The main task of the lesson acts as an understanding check where students are challenged to analyse a set of results involving the inheritance of the ABO blood group gene and the nail-patella syndrome gene to determine whether they have loci on the same chromosome and if so, how close their loci would appear to be.

This lesson describes the relationship between the structure and function of the vacuole, chloroplast and cell wall, as found in plant cells. Additional structures, such as the nucleus and mitochondria, were covered in the previous lesson on the structure of eukaryotic animal cells and the detailed content of these two lessons has been designed in parallel to cover the main content of point 2.1.1 of the AQA A-level Biology specification. The lesson begins with a task called REVERSE GUESS WHO which will challenge the students to recognise a cell structure from a description of its function. This will remind students that plant cells are eukaryotic and therefore contain a cell-surface membrane, a nucleus (+ nucleolus), a mitochondria, a Golgi apparatus, ribosomes and rough and smooth endoplasmic reticulum like the animal cells. Moving forwards, the rest of the lesson focuses on the relationship between the structure and function of the vacuole, chloroplast and cellulose cell wall. When considering the vacuole, key structures such as the tonoplast are described as well as critical functions including the maintenance of turgor pressure. A detailed knowledge of the structure of the chloroplast at this early stage of their A-level studies will increase the likelihood of a clear understanding of photosynthesis when covered in topic 5. For this reason, time is taken to consider the light-dependent and light-independent reactions and to explain how these stages are linked. The final part of the lesson challenges the students on their knowledge of cellulose as a polysaccharide as previously covered in topic 1. In addition to the focus on plant cells, the presence of chloroplasts and a cell wall in algae and the latter in fungi is also described. The previous lesson which contains the content that ties in closely with this one has been uploaded under the title “Structure of eukaryotic (animal) cells”

This detailed lesson describes the structure and properties of the cell membrane, focusing on the phospholipid bilayer and membrane proteins. Fully resourced, the PowerPoint and accompanying worksheets have been designed to cover the first part of point 2.3 of the AQA A-level Biology specification and clear links are made to Singer and Nicholson’s fluid mosaic model The fluid mosaic model is introduced at the start of the lesson so that it can be referenced at appropriate points throughout the lesson. Students were introduced to phospholipids in topic 1 and so an initial task challenges them to spot the errors in a passage describing the structure and properties of this molecule. This reminds them of the bilayer arrangement, with the hydrophilic phosphate heads protruding outwards into the aqueous solutions on the inside and the outside of the cell. In a link to some upcoming lessons on the transport mechanisms, the students will learn that only small, non-polar molecules can move by simple diffusion and that this is through the tails of the bilayer. This introduces the need for transmembrane proteins to allow large or polar molecules to move into the cell by facilitated diffusion and active transport. Proteins that act as receptors as also introduced and an opportunity is taken to make a link to an upcoming topic so that students can understand how hormones or drugs will bind to target cells in this way. Moving forwards, the structure of cholesterol is covered and students will learn that this hydrophobic molecule sits in the middle of the tails and therefore acts to regulate membrane fluidity. The final part of the lesson challenges the students to apply their newly-acquired knowledge to a series of questions where they have to explain why proteins may have moved when two cells are used and to suggest why there is a larger proportion of these proteins in the inner mitochondrial membrane than the outer membrane.

This fully-resourced lesson describes the use of vaccinations to protect individuals and populations and the differences between active and passive immunity. The engaging PowerPoint and accompanying resources have been designed to cover the fourth part of point 2.4 of the AQA A-level Biology specification and there is also a description and discussion on the concept of herd immunity. The previous lesson finished with a series of exam questions where students observed differences between the primary and secondary immune responses so the start of this lesson uses an imaginary game of TOP TRUMPS to challenge them on the depth of their understanding. This will act to remind them that a larger concentration of antibodies is produced in a quicker time in the secondary response. The importance of antibodies and the production of memory cells for the development of immunity is emphasised and this will be continually referenced as the lesson progresses. The students will learn that this response of the body to a pathogen that has entered the body through natural processes is natural active immunity. Moving forwards, time is taken to look at vaccinations as an example of artificial active immunity. Another series of questions focusing on the MMR vaccine will challenge the students to explain how the deliberate exposure to antigenic material activates the immune response and leads to the retention of memory cells. A quick quiz competition is used to introduce the variety of forms that the antigenic material can take along with examples of diseases that are vaccinated against using these methods. The eradication of smallpox is used to describe the concept of herd immunity and the students are given time to consider the scientific questions and concerns that arise when the use of this pathway is a possible option for a government. The remainder of the lesson looks at the different forms of passive immunity and describes the drawbacks in terms of the need for a full response if a pathogen is reencoutered.

This is a fast-paced lesson which uses a range of tasks and quick competitions to compare the diagnosis, symptoms and treatment of Diabetes mellitus Type I and II. Students are continually challenged throughout the lesson to build and deepen their knowledge of these conditions and consider how they can be controlled through hormone injections or lifestyle changes. Clear links are made to related topics such as auto-immune diseases and the endocrine system and progress checks have been written into the lesson to allow students to assess their understanding of all of these topics. The final part of the lesson involves the students writing a letter to an individual who has type II, explaining how this diagnosis was done, giving details of the condition and recommending lifestyle changes. This task is differentiated so that students who are finding it difficult can still access the learning. This lesson has been written for A-level students. If you are looking for a lesson for younger students on this topic, then my other upload “Diabetes Type I and II” will be more suitable.

This is an engaging and informative lesson that looks at the meaning of excretion in detail and explores the functions of the organs involved with the excretion of carbon dioxide and urea. This lesson has been designed for students studying A-level Biology. The lesson begins by introducing the definition of excretion to the students so that they are able to recognise that the substances being removed have to have come from a metabolic process in order to be excreted. This important difference to egestion (elimination) is a key detail which they need to understand at this level. Moving forwards, a quick competition is used to meet some of the organs that are involved in excretion. The remainder of the lesson focuses on the excretion of carbon dioxide. Links are made to the transport of carbon dioxide as hydrogen carbonate ions and how the affinity of haemoglobin for oxygen is affected when the carbon dioxide concentration is high. Students will meet the idea of deamination and the ornithine cycle and the key details of these two processes are covered. Progress checks have been written into this lesson at regular intervals, which challenge the students on knowledge from this lesson and prior knowledge, to enable them to constantly assess their understanding.

This is a concise, fast-paced lesson that has been designed to enable students to discover the key structural features of a synapse and be able to write accurate descriptions of the sequence of events that occur at these structures. The neurotransmitter involved is acetyl choline and therefore this is specifically a lesson about cholinergic synapses. The lesson begins by going through the terminology associated with synapses which includes pre-synaptic terminal or knob, synaptic cleft and post-synaptic neurone. Then time is taken to look at each of the two neurones and the structures found inside the terminal or on the membranes. The main task of the lesson involves a step by step guide through the sequence of events at the synapse. This guide has been written in a bullet point format and students are challenged to use the features they have met and their own Biological knowledge to complete each point. The final part of the lesson looks at how the enzyme acetylcholinesterase is involved in the breakdown and then how the neurotransmitter is re-formed using the ATP generated in the mitochondria This lesson is written for A-level students

This is an engaging and fully-resourced revision lesson which uses a range of exam questions, understanding checks, quick tasks and quiz competitions to enable students to assess their understanding of the content within topic 8 (Exchange and transport in animals) of the Edexcel GCSE Biology 9-1 specification. The specification points that are covered in this revision lesson include: Explain the need for exchange surfaces and a transport system in multicellular organisms including the calculation of surface area : volume ratio Explain how alveoli are adapted for gas exchange by diffusion between air in the lungs and blood in capillaries Describe the factors affecting the rate of diffusion, including surface area, concentration gradient and diffusion distance Explain how the structure of the blood is related to its function Explain how the structure of the blood vessels is related to their function Explain how the structure of the heart and circulatory system is related to its function, including the role of the major blood vessels, the valves Describe cellular respiration as an exothermic reaction which occurs continuously in living cells to release energy for metabolic processes, including aerobic and anaerobic respiration Compare the process of aerobic respiration with the process of anaerobic respiration Calculate heart rate, stroke volume and cardiac output, using the equation cardiac output = stroke volume × heart rate The students will thoroughly enjoy the range of activities, which include quiz competitions such as Where’s LENNY?” where they compete to recognise the blood vessel being described from the clues whilst crucially being able to recognise the areas of this topic which need their further attention. This lesson can be used as revision resource at the end of the topic or in the lead up to mocks or the actual GCSE exams.

This is a fully-resourced REVISION lesson that consists of an engaging PowerPoint (87 slides) and associated worksheets that challenge the students on their knowledge of the content of Topic 1 (Lifestyle, Health and Risk) of the Edexcel A-Level Biology A (Salters-Nuffield) specification. A wide range of activities have been written into the lesson to maintain motivation and these tasks include exam questions (with answers), understanding checks, differentiated tasks and quiz competitions. The lesson has been designed to include as much which of the content from topic 1, but the following specification points have been given particular attention: The differences between monosaccharides, disaccharides and polysaccharides, including glycogen and starch (amylose and amylopectin). Be able to relate the structures of monosaccharides, disaccharides and polysaccharides to their roles in providing and storing energy Know how monosaccharides join to form disaccharides (sucrose, lactose and maltose) and polysaccharides (glycogen and amylose) through condensation reactions forming glycosidic bonds, and how these can be split through hydrolysis reactions. Know how a triglyceride is synthesised by the formation of ester bonds during condensation reactions between glycerol and three fatty acids. Understand the course of events that leads to atherosclerosis Know how factors such as genetics, diet, age, gender, high blood pressure, smoking and inactivity increase the risk of cardiovascular disease Know the benefits and risks of treatments for CVD Understand the blood-clotting process and its role in CVD Understand how the structures of arteries and veins) relate to their functions. Understand the importance of water as a solvent in transport, including its dipole nature. This lesson can be used at numerous points over the duration of the course, as an end of topic revision aid, in the lead up to the mocks or in the lead up to the actual A-level exams.

This engaging and detailed REVISION resource has been written to encourage students to evaluate their understanding of the content found in MODULE 4.1.1 (Communicable diseases, disease prevention and the immune system) of the OCR A-Level Biology specification. The resource contains a motivating PowerPoint (86 slides) and associated worksheets which have been differentiated to support students of differing abilities in their access of the work. The lesson includes a wide range of activities such as exam questions, quick tasks and quiz competitions to motivate the students whilst they recognise those areas of the specification which require even more attention. The lesson has been designed to cover as much of the content in module 4.1.1 as possible but the following sub-topics have been given particular attention: Communicable diseases caused by bacteria, viruses and fungi Bacteria as pathogens Antigen-presenting cells The specific immune response Antibiotics and the existence of resistant strains Preventing the spread of pathogens Vaccinations Primary defences of the human body In addition to content from this module, links are made to earlier modules and challenges posed so that students can see how connections between the modules have to be made to be successful. This resource is suitable for use at the end of the module, in the lead up to AS or A2 mocks or in the lead up to the actual A-level exams.

This revision resource includes exam questions, understanding checks and quiz competitions, all of which have been designed with the aim of motivating and engaging the students whilst they assess their understanding of the content found in topic 10 (Diseases and immunity) of the CIE IGCSE Biology specification for examination in June and November 2020 and 2021. This revision resource contains an engaging PowerPoint (37 slides) and associated worksheets, some of which have been differentiated to help and challenge differing abilities. The range of activities have been designed to cover as much of the Core and Supplement content as possible but the following sub-topics have been given particular attention: Pathogens as disease causing microorganisms that cause transmissible diseases when they are spread Pathogens can be spread through direct or indirect contact Vaccinations as a form of active immunity that leads to the production of memory cells Examples of passive immunity The human body’s defence systems to include the white blood cells Diabetes type I as an example of an autoimmune disease

This lesson has been designed to cover the content set out in specification point 2.5 (g) of the WJEC GCSE Biology specification which states that students should understand that hormones are chemical messengers which control many body functions. A wide range of activities have been written into the lesson with the aim of engaging and motivating the students whilst ensuring that the content is covered in detail. These activities include a number of quiz competitions which will challenge the students to identify an endocrine organ when presented with three organs as well as introducing them to the names of some of the hormones released by the pituitary gland. The following content is covered in this lesson: The location of the pituitary, adrenal and thyroid glands in the human body The location of the pancreas, ovaries and testes in the human body The hormones which are secreted by the endocrine glands The effects of the hormones on their target organs This lesson has been written for GCSE-aged students who are studying on the WJEC Biology course but it is suitable for younger students who are looking at this as one of the different organ systems

This fully-resourced lesson covers the content of the first part of specification point 5.1.3 (d) of the OCR A-level Biology A specification that states that students should be able to demonstrate and apply an understanding of the structures and roles of synapses in nervous transmission. The majority of the lesson uses the cholinergic synapse as the example but other neurotransmitters are considered to provide the students with a wider view of this topic. The lesson begins by using a version of the WALL (as shown in the cover image) which asks the students to group 12 words into three groups of 4. Not only will this challenge their prior knowledge from topics earlier in this module but it will also lead to the discovery of four of the structures that are found in a synapse. Moving forwards, students are introduced to aectylcholine as the neurotransmitter involved at cholinergic synapses and they will start to add labels to the structures found in the pre-synaptic bulb. Time is taken to focus on certain structures such as the voltage gated channels as these types of channel were met previously when looking at the depolarisation of a neurone. There is plenty of challenge and discovery as students are pushed to explain why organelles like mitochondria would be found in large numbers in the bulb. With this process being a cascade of events, a bullet point format is used to ensure that the key content is taken in by the students and again key points like exocytosis and the action of acetylcholinesterase are discussed further. The final part of the lesson challenges the application aspect of the specification as students are introduced to unfamiliar situations in terms of synapses with new drugs like MDMA and are asked to work out and explain how these affect the nervous transmission. Understanding checks and prior knowledge checks are included throughout the lesson so that students can not only assess their progress against the current topic but also see whether they can make links to earlier topics. This lesson has been designed for students studying the OCR A-level Biology A course but could be used with very able GCSE students who are keen to develop their understanding of synapses over and above the small detail that is provided at that level. This lesson also ties in nicely with the other uploaded lessons from module 5.1.3 (neuronal communication) which are sensory receptors, neurones, nerve impulses and summation.

This engaging lesson covers the final details of specification point 6.4.2 of the AQA A-level Biology specification which states that students should be able to describe the causes and control of diabetes mellitus type I and II. The lesson has been designed to take place in a diabetes clinic where students will be challenged to perform a number of roles such as diagnosing a patient with either type I or II and to write a letter to this patient explaining how the disease was caused and any treatments that will be recommended to control the disease. It has been planned to build on the knowledge that they will have of these diseases from GCSE and links are made to other A-level topics such as the beta cells of the pancreas which they considered during the lesson on the control of blood glucose concentration. This lesson has been designed for students taking the AQA A-level Biology course and runs alongside the uploaded lesson on the control of blood glucose concentration as well as the other lessons that have been added on topic 6