A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
A Science teacher by trade, I've also been known to be found teaching Maths and PE! However, strange as it may seem, my real love is designing resources that can be used by other teachers to maximise the experience of the students. I am constantly thinking of new ways to engage a student with a topic and try to implement that in the design of the lessons.
This detailed and engaging lesson looks at the culture of transformed host cells as an in vivo method to amplify DNA fragments. Both the PowerPoint and accompanying resources have been designed to cover the third part of point 8.4.1 of the AQA A-level Biology specification and ties in with the previous two lessons in this sub-topic on producing DNA fragments and the polymerase chain reaction.
The lesson begins with the introduction of the terms transgenic and transformed. Students will learn that bacterial cells are the most commonly transformed cells so the next task challenges their recall of the structures of these cells so that plasmid DNA can be examined from that point onwards. A quick quiz competition is used to introduce the key term, vector, and then the rest of the lesson looks at the details of the five steps involved in the transformation of the host cell:
Remove and prepare the plasmid to act as a vector
Insert the DNA fragment into the vector
Transfer the recombinant plasmid into the host cell
Identify the cells which have taken up the recombinant plasmid
All the transformed host cells to replicate and express the novel gene
Time is taken to explore the finer details of each step such as the addition of the promoter and terminator regions, use of the same restriction enzyme to cut the plasmid as was used to cut the gene and the different types of marker genes. Links are continuously made to the previous lessons in this topic so that students feel confident to answer assessment questions which bring in knowledge from all of the sections.
This detailed lesson describes the structure of a nucleotide including the structure of the phosphorylated nucleotide, ATP. The engaging PowerPoint has been designed to cover point (a) of topic 6.1 as detailed in the CIE International A-level Biology specification and links are made throughout to earlier topics such as biological molecules as well as to upcoming topics like DNA structure and replication.
Students were introduced to the term monomer and nucleotide in topic 2, so the start of the lesson challenges them to recognise this latter term when only the letters U, C and T are shown. This has been designed to initiate conversations about why only these letters were used so that the nitrogenous bases can be discussed later in greater detail. Moving forwards, students will learn that a nucleotide is the monomer to a polynucleotide and that deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are two examples of this type of polymer. The main part of the lesson has been filled with various tasks that explore the structural similarities and structural differences between DNA and RNA. This begins by describing the structure of a nucleotide as a phosphate group, a pentose sugar and a nitrogenous base. Time is taken to consider the details of each of these three components which includes the role of the phosphate group in the formation of a phosphodiester bond between adjacent nucleotides on the strand. At this point students are challenged on their understanding of condensation reactions and have to identify how the hydroxyl group associated with carbon 3 is involved along with the hydroxyl group of the phosphoric acid molecule. A number of quiz rounds are used during this lesson, as a way to introduce key terms in a fun and memorable way. One of these rounds introduces adenine and guanine as the purine bases and thymine, cytosine and uracil as the pyrimidine bases and the students are shown that their differing ring structures can be used to distinguish between them. The remainder of the lesson focuses on ATP as a phosphorylated nucleotide and links are made to the hydrolysis of this molecule for energy driven reactions in cells such as active transport
Disaccharides are formed from the condensation of two monosaccharides and this lesson describes the formation of maltose, sucrose and lactose. The PowerPoint and accompanying question sheet have been designed to cover the second part of point 1.2 of the AQA A-level Biology specification but also make links to the previous lesson on monosaccharides when considering the different components of these three disaccharides.
The first section of the lesson focuses on a prefix and a suffix so that the students can recognise that the names of the common disaccharides end in -ose. In line with this, a quick quiz round is used to introduce maltose, sucrose and lactose before students are challenged on their prior knowledge as they have to describe how condensation reactions and the formation of glycosidic bonds were involved in the synthesis of each one. The main task of the lesson again challenges the students to recall details of a previous lesson as they have to identify the monomers of each disaccharide when presented with the displayed formula. Time is taken to show how their knowledge of these simple sugars will be important in later topics such as digestion, translocation in the phloem and the Lac Operon in the control of gene expression. The lesson finishes with two exam-style questions where students have to demonstrate and apply their newly acquired knowledge
This detailed and engaging lesson describes the basic structure of a mononucleotide and the similarities and differences between DNA and RNA. The PowerPoint and accompanying worksheet containing exam-style questions have been designed to cover points 2.5 (i) & (ii) of the Pearson Edexcel A-level Biology A specification.
In topic 1, the students were introduced to a number of monomers and the start of the lesson challenges them to recognise the key term nucleotide when only the letters U, C and T are shown. The next part of the lesson describes the structure of a DNA nucleotide and an RNA nucleotide so that the pentose sugar and the bases adenine, cytosine and guanine can be recognised as similarities whilst deoxyribose and ribose and thymine and uracil are seen as the differences. Time is taken to discuss how a phosphodiester bond is formed between adjacent nucleotides and their prior knowledge and understanding of condensation reactions is tested through a series of questions. Students are then introduced to the purine and pyrimidine bases and this leads into the description of the double-helical structure of DNA and the hydrogen bonds between complementary bases. The final section of the lesson describes the structure of mRNA, tRNA and rRNA and students are challenged to explain why this single stranded polynucleotide is shorter than DNA
In addition to the current understanding and prior knowledge checks, a number of quiz rounds have been written into the lesson to introduce key terms in a fun and memorable way and the final round acts as a final check on the structures of DNA and RNA.
This fully-resourced lesson describes the relationship between the structure, properties and functions of triglycerides in living organisms. The engaging PowerPoint and accompanying worksheets have been designed to be the first lesson in a series of two that cover specification points 2.1.2 (h), (i) & (j) of the OCR A-level Biology A course and the lesson contains numerous references to relevant future topics such as the importance of the myelin sheath for the conduction of an electrical impulse.
The lesson begins with a focus on the basic structure and roles of lipids, including the elements that are found in this biological molecule and some of the places in living organisms where they are found. Moving forwards, the students are challenged to recall the structure of the carbohydrates from earlier in the sub-module so that the structure of a triglyceride can be introduced. Students will learn that this macromolecule is formed from one glycerol molecule and three fatty acids and have to use their understanding of condensation reactions to draw the final structure. Time is taken to look at the difference in structure and properties of saturated and unsaturated fatty acids and students will be able to identify one from the other when presented with a molecular formula. The final part of the lesson explores how the various properties of a triglyceride mean that it has numerous roles in organisms including that of an energy store and source and as an insulator of heat and electricity.
The biological molecules sub-module is incredibly important, not just because it is found near to the start of the course, but also because of its detailed content which must be well understood to promote success with most of the other OCR A-level Biology A modules. Many hours of intricate planning have gone into the design of all of the 13 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions.
The following specification points are covered by the lessons within this bundle:
The relationship between the properties of water and its roles for living organisms
The concept of monomers and polymers and the importance of condensation and hydrolysis reactions
The chemical elements that make up biological molecules
The ring structure and properties of glucose and structure of ribose
The synthesis and breakdown of a disaccharide and a polysaccharide
The relationship between the structures, properties and functions of starch, glycogen and cellulose
The structure of a triglyceride and a phospholipid as macromolecules
The synthesis and breakdown of triglycerides
The relationship between the properties and functions of triglycerides, phospholipids and cholesterol
The general structure of an amino acid
The synthesis and breakdown of dipeptides and polypeptides
The levels of protein structure
The structure and function of globular proteins
The properties and functions of fibrous proteins
The key inorganic ions that are involved in biological processes
How to carry out and interpret the results of the chemical tests for proteins, reducing and non-reducing sugars, starch and lipids
Due to the detail of each of these lessons, it is estimated that it will take in excess of 6 weeks of allocated teaching time to cover the content.
If you would like to see the quality of the lessons, download the properties of water, glucose & ribose, amino acids and dipeptides and polypeptides lessons as these have been shared for free
The biological molecules topic is incredibly important, not just because it is found near to the start of the course, but also because of its detailed content which must be well understood to promote success with the other 18 CIE International A-level Biology topics. Many hours of intricate planning have gone into the design of all of the 11 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions.
The following specification points are covered by the lessons within this bundle:
Tests for reducing and non-reducing sugars
The iodine test for starch
The emulsion test for lipids
The biuret test for proteins
The ring forms of alpha and beta glucose
The meaning of the terms monomer, polymer, macromolecule, monosaccharide, disaccharide and polysaccharide
The formation of a glycosidic bond by a condensation reaction
The breakage of glycosidic bonds by hydrolysis reactions
The relationship between the molecular structure and functions of a triglyceride
The relationship between the structure and functions of a phospholipid
The structure of an amino acid and the formation and breakage of a peptide bond
The meaning of the different protein structures and the types of bonding that hold these molecules in shape
The molecular structure of haemoglobin and collagen as examples of globular and fibrous proteins
The relationship between the properties and roles of water in living organisms
The lesson on the biuret test for proteins and the emulsion test for lipids also contains a section which can be used for the revision of topics 2.2 and 2.3
Due to the detail of each of these lessons, it is estimated that it will take in excess of 4 weeks of allocated teaching time to cover the content.
If you would like to see the quality of the lessons, download the alpha and beta glucose, phospholipids and haemoglobin and collagen lessons as these have been shared for free
Simple and facilitated diffusion are forms of passive transport and this lesson describes the factors that increase the rate of this movement across membranes. This fully-resourced lesson is the first in a series of two that have been designed to cover specification point 2.4 of the Pearson Edexcel A-level Biology A and the involvement of channel and carrier proteins is also described and discussed.
In a number of previous lessons that covered specification points 2.1 and 2.2, students were provided with the details of gas exchange surfaces and the structure and properties of cell membranes. This lesson continually refers back to the content of these lessons so that links can be made between the movement across a cell membrane with the concentration gradient, the parts of the membrane involved and any features that may increase the rate at which the molecules move. A series of questions about the alveoli is used to demonstrate how a large surface area, a short diffusion distance and the maintenance of a steep concentration gradient will increase the rate of simple diffusion. One of two quick quiz rounds is then used to introduce temperature and size of molecule as two further factors that can affect simple diffusion. The remainder of the lesson focuses on facilitated diffusion and describes how transmembrane proteins are needed to move small, polar or large molecules from a high concentration to a lower concentration across a partially permeable membrane.
The other lesson included in this series to cover specification point 2.4 describes active transport, endocytosis and exocytosis.
This lesson describes how the polymerase chain reaction (PCR) is used to amplify DNA. The concise PowerPoint has been primarily designed to cover the detail of specification point 6.4 of the Pearson Edexcel A-level Biology A specification but also makes continual links to the previous lesson on DNA profiling where the PCR is important as well as DNA structure.
A quick quiz competition is used to introduce the PCR abbreviation before students are encouraged to discuss with the aim of identifying the enzyme involved and to recall the action of this enzyme as covered in DNA replication in topic 2. Students will learn that this reaction involves cyclical heating and cooling to a range of temperatures so another quiz is used to introduce these values. The main part of the lesson describes the main steps in the PCR and the reasons for each temperature is discussed and explained. Links are constantly made to related topics such as DNA structure are students are challenged on their understanding through exam-style questions. Time is taken to examine the key points in detail, such as the fact that the DNA polymerase used is taken from an extremophile so that it is not denatured at the high temperature.
This detailed lesson describes how the structure of a prokaryotic cell differs from the structure of an eukaryotic cell. The engaging PowerPoint and accompanying resources have been designed to cover the first part of point 2.1.2 of the AQA A-level Biology specification and describes how the size and cell structures differ and also covers the additional features that are found in some prokaryotic cells.
A clear understanding of terminology is important for A-level Biology so this lesson begins with a challenge, where the students have to add an additional prefix to their prefix and suffix table which they believe will translate as before or in front of. This leads into the discovery of the meaning of prokaryote as before nucleus and this acts to remind students that these types of cell lack this cell structure. Links to the previous lessons on the eukaryotic cells are made throughout the lesson and at this particular point, the students are asked to work out why the DNA would be described as naked and to state where it will be found in the cell. Moving forwards, the students will discover that these cells also lack membrane bound organelles and a quick quiz competition challenges them to identify the specific structure that is absent from just a single word. In addition to the naked DNA, students will learn that there are also ribosomes in the cytoplasm and will discover that these are smaller than those found in the cytoplasm of an eukaryotic cell (but the same size as those in chloroplasts and mitochondria). The remainder of the lesson focuses on the composition of the cell wall, the additional features of prokaryotic cells such as plasmids and there is also the introduction of binary fission as the mechanism by which these organisms reproduce.
This detailed lesson describes the importance of the dipole nature of water and its numerous properties to living organisms. The engaging PowerPoint and accompanying resource have been designed to cover the details of specification point 1.7 of the Edexcel A-level Biology B course and the intricate planning ensures that each role is illustrated using a specific example.
As the final lesson in the biological molecules topic, not only does this lesson cover the important content related to water but also acts as a revision tool as it checks on key topic 1 content such as condensation and hydrolysis reactions. A wide range of tasks are used to check on current understanding and prior knowledge and quick quiz competitions introduce key terms and values in a memorable way. The start of the lesson considers the structure of water molecules, focusing on the covalent and hydrogen bonds, and the dipole nature of this molecule. Time is taken to emphasise the importance of these bonds and this property for the numerous roles of water and then over the remainder of the lesson, the following properties are described and discussed and linked to real-life examples:
high specific heat capacity
polar solvent
surface tension
incompressibility
maximum density at 4 degrees Celsius
This lesson describes the formation of dipeptides & polypeptides and the different levels of protein structure. Both the engaging PowerPoint and accompanying resources have been designed to cover specification points 1.3 (ii), (iii) & (iv) of the Edexcel A-level Biology B specification and also makes continual links to previous lessons such as amino acids as well as to upcoming lessons like antibodies and enzymes so students can understand where proteins are involved.
The start of the lesson focuses on the formation of a peptide bond during a condensation reaction so that students can understand how a dipeptide is formed and therefore how a polypeptide forms when multiple reactions occur.
The main part of the lesson describes the different levels of protein structure. A step by step guide is used to demonstrate how the sequences of bases in a gene acts as a template to form a sequence of codons on a mRNA strand and how this is translated into a particular sequence of amino acids known as the primary structure. The students are then challenged to apply their understanding of this process by using three more gene sequences to work out three primary structures and recognise how different genes lead to different sequences. Moving forwards, students will learn how the order of amino acids in the primary structure determines the shape of the protein molecule, through its secondary, tertiary and quaternary structure and time is taken to consider the details of each of these. There is a particular focus on the different bonds that hold the 3D shape firmly in place and a quick quiz round then introduces the importance of this shape as exemplified by enzymes, antibodies and hormones. Students will see the differences between globular and fibrous protein and again biological examples are used to increase relevance. The lesson concludes with one final quiz round called STRUC by NUMBERS where the students have to use their understanding of the protein structures to calculate a numerical answer.
The biological molecules topic is incredibly important, not just because it is found at the start of the course, but also because of its detailed content which must be well understood to promote success with the other 9 Edexcel A-level Biology B topics. Many hours of intricate planning has gone into the design of all of the 18 lessons that are included in this bundle to ensure that the content is covered in detail, understanding is constantly checked and misconceptions addressed and that engagement is high. This is achieved through the wide variety of tasks in the PowerPoints and accompanying worksheets which include exam-style questions with clear answers, discussion points, differentiated tasks and quick quiz competitions.
The following specification points are covered by the lessons within this bundle:
The differences between monosaccharides, disaccharides and polysaccharides
The structure of glucose and ribose
The formation of disaccharides and polysaccharides from monosaccharides
The structure of starch, glycogen and cellulose
The synthesis of a triglyceride
The differences between saturated and unsaturated lipids
The relationship between the structure of lipids and their roles
The structure and properties of phospholipids
The structure of an amino acid
The formation of polypeptides and proteins
The role of ionic, hydrogen and disulphide bonding in proteins
The levels of protein structure
The structure of collagen and haemoglobin
The structure of DNA
The semi-conservative replication of DNA
A gene is a sequence of bases on DNA that codes for an amino acid sequence
The structure of mRNA
The structure of tRNA
The process of transcription
The process of translation
Base deletions, insertions and substitutions as gene mutations
The effect of point mutations on amino acid sequences
The structure of enzymes as globular proteins
The concept of specificity and the induced-fit hypothesis
Enzymes are catalysts that reduce activation energy
Understand how temperature affects enzyme activity
Enzymes catalyse a wide range of intracellular reactions as well as extracellular ones
The importance of water for living organisms
Due to the detail included in these lessons, it is estimated that it will take in excess of 2 months of allocated A-level teaching time to complete.
If you would like to see the quality of the lessons then download the monosaccharides, disaccharides and polysaccharides, glucose and ribose, triglycerides, structure of DNA and transcription lessons as these have been uploaded for free.
This clear and detailed lesson describes how ATP is formed by chemiosmosis during the process of oxidative phosphorylation. The PowerPoint has been designed to cover all of the specification points under point 5.4 of the Edexcel A-level Biology B specification and includes details of the electron transport chain, proton gradients and ATP synthase including the roles of the electron carriers, the mitochondrial membranes and oxygen.
The lesson begins with a discussion about the starting point of the reaction. In the previous stages, the starting molecule was the final product of the last stage but in this stage, it is the reduced coenzymes which release their hydrogen atoms. Moving forwards, the process of oxidative phosphorylation is covered in 7 detailed steps and at each point, key facts are discussed and explored in further detail to enable a deep understanding to be developed. Students will see how the proton gradient across the inner membrane is created and that the flow of protons down the channel associated with ATP synthase results in a conformational change and the addition of phosphate groups to ADP by oxidative phosphorylation. Understanding checks are included throughout the lesson to enable the students to assess their progress and prior knowledge checks allow them to recognise the clear links to other topics and modules.
This lesson has been written to tie in with the other uploaded lessons on the previous stages of aerobic respiration - glycolysis, the Link reaction and the Krebs cycle.
This fully-resourced lesson describes the relationship between the structure of the chloroplast and its role as the site of photosynthesis. The engaging PowerPoint and accompanying resources have been designed to cover specification point 5.7 (i) of the Edexcel A-level Biology B course.
Students were introduced to the ultrastructure of eukaryotic cells in topic 2 so this lesson has been written to build on that knowledge. A version of the quiz show POINTLESS runs throughout the lesson and this maintains engagement whilst challenging the students to recall the parts of the chloroplast based on a description which is related to their function. The following structures are covered in this lesson:
double membrane
thylakoids (grana)
stroma
intergranal lamellae
starch grains
chloroplast DNA and ribosomes
Once each structure has been recalled, a range of activities are used to ensure that key details are understood such as the role of the thylakoid membranes in the light-dependent stage and the importance of ATP and reduced NADP for the Calvin cycle.
This lesson has been specifically written to prepare students for the upcoming lessons on the light-dependent stage and light-independent stage
Respiration and photosynthesis are two of the most important biological processes, which can be poorly understood by students but unsurprisingly are commonly assessed in the terminal exams. These 8 lessons have been intricately planned so that they contain a wide range of activities that will engage the students whilst covering the key detail to try to deepen their understanding and include exam-style questions so they are prepared for the assessments.
The following specification points in topic 5 of the Edexcel A-level Biology B course are covered by these 9 fully-resourced lessons:
Cellular respiration yields ATP
The different stages of aerobic respiration
The conversion of glucose to pyruvate during glycolysis
The mitochondrial matrix as the site of the Link reaction and Krebs cycle
The production of carbon dioxide, reduced NAD and ATP in the Krebs cycle
Oxidative phosphorylation
The yield of ATP from anaerobic respiration
The production of lactate in mammalian muscles
Ethanol formation in plants
The structure of the chloroplasts
The role of thylakoid membranes in the light-dependent stage
The process of cyclic and non-cyclic photophosphorylation
The use of reduced NADP and ATP in the Calvin cycle
Understand how GALP is used as a raw material in the production of monosaccharides, amino acids and other molecules
Factors that limit photosynthesis including carbon dioxide, light intensity and temperature
Due to the detail of these lessons, it is estimated that it will take in excess of a month of A-level lessons to cover these lessons
If you would like to sample the quality of the lessons, download the link reaction, Krebs cycle and light-independent stage lessons as these have been shared for free
This lesson describes the mechanism of ventilation in mammals, including the roles of the ribcage, intercostal muscles and the diaphragm. The content of the engaging PowerPoint has been designed to cover specification point 3.1.3 (d) of the OCR A-level Biology A specification and describes the mechanism of inhalation and exhalation at rest.
The lesson begins with a focus on the diaphragm and students will discover that this sheet of muscle is found on the floor of the thoracic cavity. Whilst planning the lesson, it was deemed important to introduce this region of the body at an early stage because the best descriptions will regularly reference the changes seen in this cavity. As the mechanism of inhalation is a cascade of events, the details of this process are covered in a step by step format using bullet points. At each step, time is taken to discuss the key details which includes an introduction to Boyle’s law that reveals the inverse relationship between volume and pressure. It is crucial that students are able to describe how the actions of the diaphragm, external intercostal muscles and ribcage result in an increased volume of the thoracic cavity and a subsequent decrease in the pressure, which is below the pressure outside of the body. At this point, their recall of the structures of the mammalian gas exchange system is tested, to ensure that they can describe the pathway the air takes on moving into the lungs.
The remainder of the lesson involves a task which challenges the students to describe exhalation and then the accessory muscles involved in forced ventilation are also considered.
Respiration and photosynthesis are two of the most commonly-assessed topics in the terminal A-level exams but can be the least well understood by students. These 11 lessons have been intricately planned to contain a wide range of activities that will engage the students whilst covering the key detail to try to deepen their understanding and include exam-style questions so they are prepared for these assessments.
The following specification points in topics 5.1 and 5.2 of the AQA A-level Biology course are covered by these lessons:
The photoionisation of chlorophyll
The production of ATP and reduced NADP through the transfer of electrons and pumping of protons across the thylakoid membrane
Photolysis of water to produce protons, electrons and oxygen
The use of the products of the light-dependent reaction in the Calvin cycle
Carbon fixation involving RUBISCO
The reduction of GP to TP
The regeneration of RuBP from TP
The conversion of TP to organic substances
The environmental factors that limit the rate of photosynthesis
Respiration produces ATP
Glycolysis as the first stage of aerobic and anaerobic respiration
The conversion of pyruvate to ethanol or lactate using reduced NAD
The key details of the Link reaction, Krebs cycle and oxidative phosphorylation
The metabolic pathways of other respiratory substrates
Due to the detail of these lessons, it is estimated that it will take in excess of a month of A-level lessons to cover these specification points
If you would like to sample the quality of the lessons, download the chloroplast structure, anaerobic respiration and oxidative phosphorylation lessons as these have been shared for free
This fully-resourced lesson describes the movement of molecules by active transport, endocytosis and exocytosis. The PowerPoint and accompanying worksheets have been designed to cover the second part of specification points 2.5 (i) & (ii) of the Edexcel International A-level Biology specification and describes the role of ATP as an immediate source of energy as well as the role of the carrier proteins.
ATP is introduced at the start of the lesson and students will learn that this molecule is a phosphorylated nucleotide so they are able to make appropriate links when they cover the structure of DNA and RNA later in topic 2. Students will learn that adenosine triphosphate is the universal energy currency and that the hydrolysis of this molecule can be coupled to energy-requiring reactions within the cell and the rest of the lesson focuses on the use of this energy input for active transport, endocytosis and exocytosis. Students are challenged to answer a series of questions which compare active transport against the forms of passive transport and to use data from a bar chart to support this form of transport. In answering these questions they will discover that carrier proteins are specific to certain molecules and time is taken to look at the exact mechanism of these transmembrane proteins. A quick quiz round introduces endocytosis and the students will see how vesicles are involved along with the energy source of ATP to move large substances in or out of the cell. The lesson concludes with a link to a future topic as the students are shown how exocytosis is involved in a synapse.
