This engaging lesson describes the relationship of the fibrous and globular structure of proteins to their function. The PowerPoint and accompanying resource have been primarily designed to cover specification point (j) as detailed in AS unit 1, topic 1 of the WJEC A-level Biology course but due to the detailed coverage of haemoglobin, the start of this lesson could also be used when teaching lessons that cover specification points in AS unit 2, topic 3 on adaptations for transport By the end of the lesson, students will be able to describe that the interactions of the hydrophobic and hydrophilic R groups results in different shapes which differ in their solubility in water and be able to explain the importance of this property with reference to the individual functions of proteins, specifically collagen and haemoglobin. They will also be able to name key individual details for each protein, such as haemoglobin being a conjugated protein and collagen having repeating units and being wound into a triple helix Extra time has gone into the planning of this lesson to ensure that links are continuously made to previous topics such as amino acids and the levels of protein structure as well as to upcoming topics

This fully-resourced lesson describes the light-dependent stage, including the production of ATP by cyclic and non-cyclic photophosphorylation. The detailed PowerPoint and accompanying resources have been designed to cover specification points 5.7 (ii) & (iii) of the Edexcel A-level Biology course and has been planned to link with the previous lesson on the structure of the chloroplast and to prepare for the next lesson on the light-independent stage. This is a topic which students tend to find difficult so this lesson has been intricately planned to walk them through each of the key steps of the light-dependent stage. Time is taken to describe the roles of the major protein complexes that are embedded in the thylakoid membrane and this includes the two photosystems, the proton pump and ATP synthase. A series of exam-style questions have been written that link to other biological topics in this course such as cell structure and membrane transport as well as application questions to challenge them to apply their understanding. Some of these resources have been differentiated to allow students of differing abilities to access the work and to be pushed at the same time. Students will learn that there are two pathways that the electron can take from PSI and at the completion of the two tasks which describe each of these pathways, they will understand how ATP is generated in non-cyclic and cyclic fashion. The final task of the lesson asks them to compare these two forms of photophosphorylation to check that they understand when photolysis is involved and reduced NADP is formed. Due to the detail included in this lesson, it is estimated that it will take in excess of 2.5 hours of allocated A-level teaching time to complete.

This fully-resourced lesson describes how polygenic inheritance gives rise to phenotypes that show continuous variation. The engaging PowerPoint and accompanying resources have been primarily designed to cover points 3.20 (i) & 3.21 of the Edexcel International A-level Biology specification but also includes activities to challenge the students on previous concepts in topics 3 and 2. The students begin the lesson by having to identify phenotype and species from their respective definitions so that a discussion can be encouraged where they will recognise that phenotypic variation within a species is due to both genetic and environmental factors. The main part of the the lesson focuses on these genetic factors, and describes how mutation and the events of meiosis contribute to this variation. A range of activities, which include exam-style questions and quick quiz rounds, are used to challenge the students on their knowledge and understanding of substitution mutations, deletions, insertions, the genetic code, crossing over and independent assortment. Moving forwards, the concept of multiple alleles is introduced and students will learn how the presence of more than 2 alleles at a locus increases the number of phenotypic variants. Another quick quiz round is used to introduce polygenic inheritance and the link is made between this inheritance of genes at a number of loci as an example of continuous variation. The final part of the lesson describes a few examples where environmental factors affect phenotype, such as chlorosis in plants. As this is the final lesson in topic 3, the numerous activities can be used for revision purposes and to demonstrate the links between different biological topics.

This revision resource has been written to include a range of activities that motivate the students whilst they assess their understanding of the content found in module 2.1.5 (Biological membranes) of the OCR A-level Biology A specification. The resource includes a detailed and engaging Powerpoint (71 slides) and associated worksheets The range of activities have been designed to cover as much of the content as possible but the following sub-topics have been given particular attention: The movement of molecules by active transport which requires ATP as an immediate source of energy The movement of molecules by passive processes The use of membrane-spanning proteins in facilitated diffusion and active transport Factors that increase the rate of simple diffusion The movement of water across membranes by osmosis The effects that solutions of different water potentials can have on animal and plant cells The fluid mosaic model of membrane structure The roles of the components of the plasma cell membrane In addition to these topics, some topics from other modules such as organelles, synapses and autoimmune diseases are tested in order to challenge the students on their ability to make links between the modules. The range of activities include exam questions and understanding checks as well as quiz competitions to maintain student engagement.

This revision resource includes exam questions, understanding checks and quiz competitions, all of which have been designed with the aim of motivating and engaging the students whilst they assess their understanding of the content found in topic 1.2 (Respiration and the respiratory system in humans) of the WJEC GCSE Biology specification. The range of activities have been designed to cover as much of the content as possible but the following sub-topics have been given particular attention: The need and purpose of the respiratory system The function of the mucus and cilia in the trachea and the effect of smoking on these structures The structure of the alveolus and its blood supply The mechanisms of inspiration and expiration The process of aerobic respiration and the release of energy in the form of ATP Anaerobic respiration and the production of lactic acid

The range of exam questions, understanding checks and quiz competitions that have been written into this revision lesson will help to motivate and engage the students whilst they assess their understanding of the content found in topic 1.3 (Digestion and the digestive system in humans) of the WJEC GCSE Biology specification. The resource includes a detailed and engaging Powerpoint (51 slides) and an associated worksheet, which has been differentiated to help differing abilities to access the work. The range of activities have been designed to cover as much of the content as possible but the following sub-topics have been given particular attention: The movement of food by peristalsis The role of carbohydrase, protease and lipase enzymes in digestion The tests for the presence of starch and glucose The roles of the stomach and small intestine in digestion The function of bile in the break down of fats The need for a balanced diet and implication for health of excess sugar and salt in foods

This revision resource includes a range of activities that will act to engage and motivate the students whilst they assess their understanding of the Animal nutrition content (topic B6) of the CIE IGCSE Combined Science specification for examination in June and November 2020 and 2021. There are exam questions with explained answers as well as quick tasks and quiz competitions such as “Have you got the right BALANCE” where students are challenged to recognise whether a statement about the balanced diet is accurate or not. The lesson was designed to cover as much content as possible but the following topics have received particular attention: Mechanical digestion Chemical digestion by digestive enzymes Amylase and the break down of starch The adaptations of the small intestine to allow absorption The roles of the hydrochloric acid in gastric juice The break down of lipids in the small intestine The components of a balanced diet This resource includes a detailed and engaging PowerPoint (51 slides) and a worksheet which is differentiated two ways. Efforts have been made to make links to other topics such as enzymes (B4) so students can see the importance of being able to make connections in their answers

This revision resource contains an engaging and detailed PowerPoint (66 slides) and associated worksheets, all of which are differentiated to allow students of different abilities to access the work. The range of activities that include exam questions with explained answers and quiz competitions covers the content within topic 11 (Air and water) of the CIE IGCSE Chemistry specification for examination in June and November 2020 and 2021. The resource was written to cover as much of the content as possible but the following topics have received particular attention: The fractional distillation of air to separate oxygen and nitrogen The composition of clean air The variety of reactions that form carbon dioxide The changes in the atmospheric levels of carbon dioxide and the link to global warming The common pollutants and their effects on health and buildings The treatment of water to make it safe The chemical tests for water The conditions needed for the Haber Process Efforts have been made during the design of this lesson to make connections between topic 11 and the other topics in order to show students how important it is to make Biological links. In addition, there is a big emphasis on mathematical skills and guidance is given throughout to break down any barriers that students may have with these types of questions.

This fully-resourced lesson has been designed to cover the specification points about sex-linked characteristics as detailed in the supplement section of topic 17 (inheritance) of the CIE IGCSE Biology specification This resource consists of an engaging and detailed PowerPoint and an accompanying worksheet, which has been differentiated two ways so students who find the tasks difficult are given assistance to result in good outcomes. The lesson builds on the knowledge from earlier in the topic on monohybrid crosses and sex determination to show students how to draw genetic diagrams to calculate offspring outcomes when the gene is carried on the sex chromosomes. Step by step guides are used to demonstrate how to write the genotypes and gametes in these disorders by including the sex chromosomes to show gender. The lesson focuses on red-green colour blindness and haemophilia and builds up to questions on a pedigree tree to challenge the students to apply their new knowledge. This lesson has been designed for GCSE-aged students who are studying the CIE IGCSE Biology course but is suitable for A-level students who are looking at these types of genetic disorders.

This resource has been designed to cover the higher tier content of specification point 5.3.6 as detailed in the AQA GCSE Biology & Combined Science specifications. The lesson takes the format of a day at a fertility clinic and students will see how three couples, who are at different stages of their currently unsuccessful journey to getting pregnant, are advised and the treatments that could be on offer to them. Discussion points are included throughout the lesson to encourage the students to talk about the Biology and to allow any misconceptions to be addressed if and when they arise. In addition, previous knowledge checks are regular so that the links between this topic and earlier ones such as the hormones in human reproduction and contraception can be made. Students will learn how a fertility drug may be made available and will be challenged to explain why FSH and LH would be the reproductive hormones contained in these substances. The main focus of the lesson is IVF treatment and this main task culminates with students gaining a number of key points in the for and against argument before being challenged to continue this as a set homework in the form of an evaluation. Quiz competitions are used to introduce key terms in a fun and memorable way and the final task is a mathematical skills check where students will be able to compare the high number of multiple births that are associated with this treatment as compared to the number from natural births. This lesson has been designed for students studying the AQA GCSE Biology or Combined Science course but is suitable for older students who are looking at this topic.

This fully-resourced revision lesson covers the CORE and SUPPLEMENT sections of topic P4 (Properties of waves, including light and sound) of the CIE IGCSE Combined Science specification. The engaging PowerPoint and acccompanying resource have been written to include a wide range of activities which include exam-style questions (with clearly explained answers), differentiated tasks and quick quiz competitions. These activities challenge the following specification points: State the meaning of speed, frequency, wavelength and amplitude Distinguish between transverse and longitudinal waves and give examples Describe how waves can undergo reflection and refraction and that the latter is caused by a change in the wave speed Recall and use the law of reflection Describe the main features of the EM spectrum State that all waves travel at the speed of light in a vacuum and recall this speed Describe the uses of the EM waves Describe the longitudinal nature of sound waves Recall and use the equation to calculate wave speed Describe how to measure the speed of sound in air and ripples on water surfaces Recall that sound waves can be ultrasound To fall in line with the greater mathematical content of the specification, there is a large emphasis on a range of mathematical skills in this lesson which includes the use of standard form. Due to the detail of this lesson, it is estimated that it will take in excess of 2 hours of IGCSE-allocated teaching time to cover the content and this allows this to be used at the end of the topic or in the lead up to mock or terminal examinations.

A fully-resourced lesson, which explores how changes to the sequence of bases on DNA may or may not alter protein structure. The engaging PowerPoint and accompanying resources have been designed to cover point 8.1 of the AQA A-level Biology specification and it builds on the knowledge gained during topic 4 when gene mutations were first introduced. A quiz runs throughout the lesson where students compete to recognise key terms from their definitions and the lesson begins with an edition of this round as they are challenged to recognise the definition for primary structure. Other terms that arise during the lesson relate to the different gene mutations, the genetic code and mutagenic agents. The focus of the lesson is to support students in their explanations of how a particular mutation can result in a change in the primary structure as well as being able to explain why a substitution mutation may not. In this way, their understanding of the degenerate and non-overlapping nature of the genetic code will be tested and any misconceptions can be addressed. The main section of the lesson covers substitution, deletion and addition mutations before translocation, inversion and duplication mutations are introduced. Links are made to the latter parts of topic 8 so students can understand how the change in the sequence of bases may disrupt gene expression. The final part of the lesson looks at a range of mutagenic agents that can increase the rate of mutation.

This detailed and engaging lesson describes the structural similarities and differences between DNA and RNA. The PowerPoint and accompanying worksheet containing exam-style questions have been designed to cover point 1.5.1 of the AQA A-level Biology specification. In the first lesson of topic 1, the students were introduced to a number of monomers which included a nucleotide. In line with this, the start of the lesson challenges them to recognise the key term nucleotide when only the letters U, C and T are shown. The next part of the lesson describes the structure of a DNA nucleotide and an RNA nucleotide so that the pentose sugar and the bases adenine, cytosine and guanine can be recognised as similarities whilst deoxyribose and ribose and thymine and uracil are seen as the differences. Time is taken to discuss how a phosphodiester bond is formed between adjacent nucleotides and their prior knowledge and understanding of condensation reactions is tested through a series of questions. Students are then introduced to the purine and pyrimidine bases and this leads into the description of the double-helical structure of DNA and the hydrogen bonds between complementary bases. The final section of the lesson describes the structure of mRNA, tRNA and rRNA and students are challenged to explain why this single stranded polynucleotide is shorter than DNA In addition to the current understanding and prior knowledge checks, a number of quiz rounds have been written into the lesson to introduce key terms in a fun and memorable way and the final round acts as a final check on the structures of DNA and RNA.

This fully-resourced lesson describes how phenotype is the result of an interaction between genotype and the environment and can be affected by multiple alleles at many gene loci. The engaging PowerPoint and accompanying resources have been primarily designed to cover points 3.14 (i) & 3.15 of the Pearson Edexcel A-level Biology A specification but also includes activities to challenge the students on previous concepts in topics 3 and 2. The students begin the lesson by having to identify phenotype and species from their respective definitions so that a discussion can be encouraged where they will recognise that phenotypic variation within a species is due to both genetic and environmental factors. The main part of the the lesson focuses on these genetic factors, and describes how mutation and the events of meiosis contribute to this variation. A range of activities, which include exam-style questions and quick quiz rounds, are used to challenge the students on their knowledge and understanding of substitution mutations, deletions, insertions, the genetic code, crossing over and independent assortment. Moving forwards, the concept of multiple alleles is introduced and students will learn how the presence of more than 2 alleles at a locus increases the number of phenotypic variants. Another quick quiz round is used to introduce polygenic inheritance and the link is made between this inheritance of genes at a number of loci as an example of continuous variation. The final part of the lesson describes a few examples where environmental factors affect phenotype, such as chlorosis in plants. As this is the final lesson in topic 3, the numerous activities can be used for revision purposes and to show the links between different biological topics.

This lesson describes the light-dependent stage of photosynthesis and focuses on the mechanisms involved in the production of ATP and reduced NADP. The detailed PowerPoint and accompanying resources have been designed to cover the details of point 5.2.1 (d) of the OCR A-level Biology A specification and has been specifically planned to link with the previous lesson on the structure of the chloroplast and photosynthesis and to prepare the students for the next lesson on the light-independent stage. The light-dependent stage is a process which students can find difficult to understand in the necessary detail so this lesson has been planned to walk them through all of the key details. Time is taken to describe the roles of the major protein complexes that are embedded in the thylakoid membrane and this includes the two photosystems, the cytochrome proton pump and ATP synthase. A series of exam-style questions have been written that link to other biological topics in this course such as eukaryotic cell structures and membrane transport as well as application questions to challenge them to apply their understanding. Some of these resources have been differentiated to allow students of differing abilities to access the work and to be pushed at the same time. Students will learn that there are two pathways that the electron can take from PSI and at the completion of the two tasks which describe each of these pathways, they will understand how ATP is generated in non-cyclic and cyclic photophosphorylation. The final task of the lesson asks them to compare these two forms of photophosphorylation to check that they understand when photolysis is involved and reduced NADP is formed. Due to the detail included in this lesson, it is estimated that it will take in excess of 2.5 hours of allocated A-level teaching time to complete.

This lesson describes how the eyepiece graticule and stage micrometer are used in the measurement of cells. The engaging PowerPoint and accompanying resources have been designed to cover point 1.1 [c] of the CIE A-level Biology specification and also includes a number of tasks that have been written to ensure that students are able to recognise the millimetre, micrometre and nanometre as units of size and that they are able to convert between them. As this content is part of topic 1.1, it is likely that this lesson on the measurement of cells and the units of size will be one of the first that students will encounter in this A-level course. With this in mind, this lesson and the next two on microscopes and calculating actual size have been specifically written to contain a wide variety of tasks, including an ongoing quiz competition. This will act to maintain engagement in a topic that can sometimes discourage students at this early stage of the course whilst ensuring that the key content is covered and understanding is constantly checked. A step by step guide walks them through the use of the scale on the stage micrometer to identify the size of the divisions of the eyepiece graticule and then they are challenged to apply this method to a series of questions. Useful hints are provided throughout the lesson and students will be able to confidently convert between metres, millimetres, micrometres and nanometres by the end of the lesson A quiz scoresheet is included with the lesson so that teachers can keep track of the points won in the different rounds and add them to those won in the upcoming lessons in topic 1.1

This fully-resourced lesson describes how reproductive isolation can lead to allopatric and sympatric speciation. The engaging PowerPoint and accompanying resources have been designed to cover point 3.2 (iii) of the Edexcel A-level Biology B specification. The lesson begins by using the example of a hinny, which is the hybrid offspring of a horse and a donkey, to challenge students to recall the biological classification of a species. Moving forwards, students are introduced to the idea of speciation and the key components of this process, such as isolation and selection pressures, are covered and discussed in detail. Understanding and prior knowledge checks are included throughout the lesson to allow the students to not only assess their progress against the current topic but also to make links to earlier topics in the specification. Time is taken to look at the details of allopatric speciation and how the different mutations that arise in the isolated populations and genetic drift will lead to genetic changes. The example of allopatric speciation in wrasse fish because of the isthmus of Panama is used to allow the students to visualise this process. The final part of the lesson considers sympatric speciation and again a wide variety of tasks are used to enable a deep understanding to be developed.

This fully-resourced lesson describes the ultrastructure of an eukaryotic cell and describes the relationship between the structure and function of the organelles. The detailed and engaging PowerPoint and accompanying resources have been designed to cover point 2.1 (v) of the Edexcel A-level Biology B specification As cells are the building blocks of living organisms, it makes sense that they would be heavily involved in all of the 10 topics in the Edexcel A-level B course and intricate planning has ensured that links are made to topic 1 and details are provided to link to the upcoming topics. A wide range of activities, that include exam-style questions, class discussion points and quick quiz competitions, will maintain motivation and engagement whilst covering the finer details of the following structures and organelles: nucleus nucleolus ribosomes rough endoplasmic reticulum Golgi apparatus lysosomes smooth endoplasmic reticulum mitochondria cell surface membrane centrioles vacuole (+ tonoplast) chloroplasts cell wall As mentioned above, all of the worksheets have been differentiated to support students of differing abilities whilst maintaining challenge Due to the detail that is included in this lesson, it is estimated that it will take in excess of 3 hours of allocated A-level teaching time to cover the work

This lesson describes the relationship between the structure and function of the xylem and phloem in transport. The engaging and detailed PowerPoint and accompanying resources have been designed to cover point 4.7 (i) of the Edexcel A-level Biology B specification. The lessons begins by challenging the students to identify the substances that a plant needs for the cellular reactions, where they are absorbed and where these reactions occur in a plant. The aim of this task is to get the students to recognise that water and mineral ions are absorbed in the roots and needed in the leaves whilst the products of photosynthesis are in the leaves and need to be used all over the plant. Students will be reminded that the xylem and phloem are part of the vascular system responsible for transporting these substances and then the rest of the lesson focuses on linking structure to function. A range of tasks which include discussion points, exam-style questions and quick quiz rounds are used to describe how lignification results in the xylem as a hollow tube of xylem cells to allow water to move as a complete column. They will also learn that the narrow diameter of this vessel allows capillary action to move water molecules up the sides of the vessel. The same process is used to enable students to understand how the structures of the companion cells allows assimilates to be loaded before being moved to the sieve tube elements through the plasmodesmata.